Integrative bioinformatics and machine learning approach unveils potential biomarkers linking coronary atherosclerosis and fatty acid metabolism-associated gene by Hong Li, Yongyun Xu, Aiting Wang, Chuanxin Zhao, Man Zheng, Chunyan Xiang

“…Subsequently, Lasso regression and SVM-RFE were applied to identify key hub genes and assess the diagnostic efficacy of seven FAMGs in distinguishing AS. …”
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Detection of I491F and V170F rpoB mutations associated with misdiagnosis of rifampicin resistance among patients with drug-susceptible tuberculosis treatment failure, Myanmar, 2022 by Phyu Win Ei, Mi Mi Htwe, Myat Htut Nyunt, Aye Su Mon, Zaw Myint, Wint Wint Nyunt, Su Mon Win, Sandar Aung, Wai Myat Thwe, Wah Wah Aung

“…This study aimed to find out RIF resistance missed by routine diagnostic assays using next generation genome sequencing tool. …”
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Serum matrix metalloproteinase‐7, Syndecan‐1, and CA 19‐9 as a biomarker panel for diagnosis of pancreatic ductal adenocarcinoma by Doron Yablecovitch, Moshe Nadler, Shomron Ben‐Horin, Orit Picard, Miri Yavzori, Ella Fudim, Moran Tardio Duchan, Emad Sakhnini, Alon Lang, Maor Lahav, Talia Saker, Sandra Neuman, Limor Selinger, Biana Freitz, Revital Dvir, Maria Raitses‐Gurevich, Talia Golan, Idan Levy, Ido Laish

“…We aimed to evaluate the diagnostic and prognostic performance of these serum proteins, as potential biomarkers, in patients with pancreatic ductal adenocarcinoma (PDAC) and benign pancreatic cysts. …”
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Screening of breast cancer in higher-risk Taiwanese women using contrast-enhanced mammography by Chen-Pin Chou, Yu-Ting Hong, Yun Lin, Pei-Ying Lin

“…Background: To assess the diagnostic performance of contrast-enhanced mammography (CEM) in screening higher-risk Taiwanese women for breast cancer. …”
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The Development of Methods of BLOTCHIP^®-MS for Peptidome: Small Samples in Tuberous Sclerosis by Kunio Yui, George Imataka, Kotaro Yuge, Hitomi Sasaki, Tadashi Shiohama, Kyoichi Asada, Hidehisa Tachiki

“…PMEL and SAM were significantly changed as diagnostic effects.…”
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Advantages of using T1-mapping in cardiac magnetic resonance imaging in patients with acromegaly by Alina A. Almaskhanova, Konstantin V. Melkozerov, Elena G. Przhiyalkovskaya, Natalia V. Tarbaeva, Anastasya Y. Korneluk, Raisa S. Kosharnaia, Victor Y. Kalashnikov, Zhanna E. Belaya, Galina A. Mel'nichenko, Natalia G. Mokrysheva

“…The ROC analysis (Receiver Operator Characteristic) determined the diagnostic value of post-contrast T1-mapping: AUC (Area Under the Curve)=0.906 (95% confidence interval 0.789–1.000), a sensitivity of 90%, and a specificity of 76.5%, indicating high diagnostic efficiency. …”
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Noninvasive hemodynamic assessment of type 2 diabetes mellitus using four-dimensional flow magnetic resonance imaging by Di Wu, Jiachen Ji, Yuancheng Wang, Shujun Zhang, Hong Ge, Mingzhu Fu, Yunduo Li, Shenghong Ju, Rui Li

“…The reproducibility of these measurements was assessed with Bland-Altman analysis, differences between groups were evaluated using t-tests, and their diagnostic utility for T2DM and DN was analyzed using ROC curves. …”
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Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma by Koržinek Martha, Ćelap Ivana, Fabijanec Marija, Žanić Tena, Ljubičić Neven, Baršić Neven, Verbanac Donatella, Barišić Karmela, Rajković Marija Grdić

“…Moreover, Receiver Operating Characteristic (ROC) analysis revealed poor diagnostic accuracy, for all tested parameters (AUC was 0.7 or less). …”
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Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model by KiyomitsuFujimoto, TakashiKanamoto, ShunyaOtani, RyoMiyazaki, KosukeEbina, KenNakata

“…The purpose of this study was to examine the diagnostic accuracy of ultrasound for abnormal skeletal muscle lesions, and to examine the distribution patterns of solution and cells injected into abnormal muscle lesions under ultrasound guidance. …”
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Gallbladder Wall Thickness as a Non-Invasive Tool for Prediction of Esophageal Varices in Patients with Hepatitis C Related Chronic Liver Disease by Munir Ahmed, Maliha Aziz, Shahzad Riyaz, Mohammad Salih, Rashed Nazir, Muslim Atiq

“…GBWT at a cutoff value of 3 mm predicted EVs in patients with HCV-CLD with a sensitivity of 79.37%, specificity of 89.47%, PPV of 98.04%, NPV of 39.53%, diagnostic accuracy of 80.67% with AUC of 0.882. GBWT at 3.7mm predicted advanced/high-risk varices with a sensitivity of 80.65%, specificity of 75.76%, PPV of 90.36%, NPV of 58.15%, and diagnostic accuracy of 79.37% with AUC of 0.813. …”
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Colorectal Peritoneal Metastases: A Systematic Review of Current and Emerging Trends in Clinical and Translational Research by Foteini Stefania Koumpa, Diamantis Xylas, Maciej Konopka, Dieter Galea, Kirill Veselkov, Anthony Antoniou, Akash Mehta, Reza Mirnezami

“…Acquired data were then divided into hierarchical thematic categories (imaging modalities, translational biomarkers (diagnostic/prognostic/therapeutic), and delivery techniques) and subcategories. …”
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Impact of delayed pelvic imaging on the staging of biochemical recurrence in prostate cancer patients using [18F]DCFPYL PET/CT: a retrospective evaluation by Ana Rodríguez-Pajuelo, Miriam Guerra-Gómez, Juan Ignacio Cuenca Cuenca, José María Freire-Macías, José Manuel Jiménez-Hoyuela García, Rosa María Álvarez-Pérez

“…Abstract Purpose The aim of this study was to evaluate the added diagnostic value of additional second stage pelvic scanning as part of the [18F]DCFPYL PET/CT procedure in patients treated for prostate cancer (PCa) who have biochemical recurrence (BR). …”
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Protocol for development of an assessment tool for competency of ECG interpretation: expert consensus by the RAND/UCLA appropriateness method and cross-sectional testing using mult... by Shinji Inaba, Toshi A Furukawa, Osamu Yamaguchi, Masatsugu Sakata, Kazumichi Yamamoto, Tomohiro Kaga, Muhammad Wannous

“…Introduction Although the ECG is an important diagnostic tool in medical practice, the competency of ECG interpretation is considered to be poor. …”
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Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores by Timing Liu, Alagu Sankareswaran, Gordon Paterson, Genes & Health Research Team, Diane P. Fraser, Sam Hodgson, Qin Qin Huang, Teng Hiang Heng, Meera Ladwa, Nick Thomas, David A. van Heel, Michael N. Weedon, Chittaranjan S. Yajnik, Richard A. Oram, Giriraj R. Chandak, Hilary C. Martin, Sarah Finer

“…Using linked health records from the Genes & Health cohort (n = 38,344) we defined two reference groups meeting stringent diagnostic criteria: 31 T1D cases, 1842 T2D cases, and after excluding these, two further groups: 839 insulin-treated diabetic individuals with ambiguous features and 5174 non-diabetic controls. …”
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Comparative study of PCR test kits for ASFV DNA detection by M. S. Krasnikova, S. P. Yatsentyuk, M. B. Bryusova, A. D. Kozlova, М. А. Gergel

“…The results of this study demonstrate the need for control of the manufactured diagnostic kits used in state programs for animal disease monitoring.…”
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Upskilling or deskilling? Measurable role of an AI-supported training for radiology residents: a lesson from the pandemic by Mattia Savardi, Alberto Signoroni, Sergio Benini, Filippo Vaccher, Matteo Alberti, Pietro Ciolli, Nunzia Di Meo, Teresa Falcone, Marco Ramanzin, Barbara Romano, Federica Sozzi, Davide Farina

“…Abstract Objectives This article aims to evaluate the use and effects of an artificial intelligence system supporting a critical diagnostic task during radiology resident training, addressing a research gap in this field. …”
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The Role of Positron Emission Tomography Imaging in Breast Implant Illness by Siham Azahaf, MD, Karlinde A. Spit, MD, Christel J.M. de Blok, MD, PhD, Peter Bult, MD, PhD, Prabath W.B. Nanayakkara, MD, PhD, FRCP

“…However, given inherent limitations, further research is warranted to fully assess its potential diagnostic utility in breast implant illness.…”
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A customizable multiplex protein microarray for antibody testing and its application for tick-borne and other infectious diseases by Hari Krishnan Krishnamurthy, Vasanth Jayaraman, Karthik Krishna, Tianhao Wang, Kang Bei, Chithra Changalath, Shiny Matilda, Alex J. Rai, Renata Welc-Falęciak, Agnieszka Pawełczyk, Lucas S. Blanton, Aleš Chrdle, Andrea Fořtová, Daniel Růžek, Gheyath K. Nasrallah, Laith J. Abu-Raddadi, Duaa W. Al-Sadeq, Marah Abed Alhakim Abdallah, Daniele Lilleri, Chiara Fornara, Piera D’Angelo, Milena Furione, Maria Söderlund-Venermo, Klaus Hedman, Dimosthenis Chochlakis, Eirini Makridaki, Artemis Ntoula, Anna Psaroulaki, Angélica Escárcega-Ávila, John J. Rajasekaran

“…The diagnostic tests currently available for tick-borne diseases are severely limited in their ability to provide accurate results and cannot detect multiple pathogens in a single run. …”
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Autism spectrum disorder, social anxiety and obsessive–compulsive disorders: beyond the comorbidity by Liliana Dell’Osso, Giulia Amatori, Chiara Bonelli, Benedetta Nardi, Enrico Massimetti, Ivan Mirko Cremone, Stefano Pini, Barbara Carpita

“…In the analysis of PAS-SV scores, the ASD group once again achieved the highest scores after the PD individuals, although this time the difference was not statistically significant compared to the other diagnostic groups. Discussion These findings highlight the central role of the autism spectrum in SAD and OCD diagnoses. …”
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Diagnosis of Gestational Diabetes Mellitus with Point-of-Care Methods for Glucose versus Hospital Laboratory Method Using Isotope Dilution Gas Chromatography-Mass Spectrometry as R... by Karl Kristensen, Anne-Marie Wangel, Anastasia Katsarou, Nael Shaat, David Simmons, Helena Fadl, Kerstin Berntorp

“…Diagnosis was based on the World Health Organization 2013 diagnostic thresholds for fasting (n=135), 1 h (n=52), and 2 h (n=135) glucose measurements. …”
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