Targeting the activated allosteric conformation of the endothelin receptor B in melanoma with an antibody-drug conjugate: mechanisms and therapeutic efficacy by Amaury Herbet, Marie Hautière, Frédéric Jean-Alphonse, Delphine Vivier, Christophe Leboeuf, Narciso Costa, Aloïse Mabondzo, Guilhem Bousquet, Franck Denat, Eric Reiter, Didier Boquet

“…RB49 could be used as a diagnostic tool for patient stratification.…”
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A computational role of blood nanofluid induced by a stenosed artery with porous medium and thermophoretic particle deposition effects by Shivalila Hangaragi, N. Neelima, N. Beemkumar, Ankur Kulshreshta, Umair Khan, Noreen Sher Akbar, Mohammad Kanan, Mona Mahmoud

“…The novel outcomes of this research highlight the effectiveness of deep learning models in predicting and analyzing stenotic blood flow conditions, contributing to improved diagnostic approaches to improve the patient's healthcare and reduce the mortality rate.…”
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Latin America’s Dengue Outbreak Poses a Global Health Threat by Michelle Teixeira de Almeida, Davi Gabriel Salustiano Merighi, Aline Biazola Visnardi, Cauê Augusto Boneto Gonçalves, Vitor Martins de Freitas Amorim, Anielle Salviano de Almeida Ferrari, Anacleto Silva de Souza, Cristiane Rodrigues Guzzo

“…In this regard, our review analyzes prevention measures and therapeutic protocols during the outbreak while addressing DENV transmission dynamics, clinical presentations, and epidemiological shifts. It also evaluates diagnostic strategies combining clinical assessment with serological and molecular testing, providing information to improve diagnostic and preventive measures. …”
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From dyspnea to Olympic qualification - A case report as a model for post-acute sequelae of COVID-19 by Baudrexl JC, Steinestel K, Gagiannis D

“…The present case highlights the need for an individualised diagnostic and therapeutic approach and that complete remission of PASC can be achieved. …”
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Delayed Speech in Children as a Symptom; Socio-demographic Features and Accompanying Clinical Diagnosis by Damla Eyuboglu, Murat Eyuboglu

“…The aim of this study was to review the clinical diagnosis of children with delayed speech who were referred to the pediatric psychiatry clinic and conduct a comparative study on the diagnostic groups in terms of their sociodemographic characteristics. …”
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The Care Pathway Delays of Cervical Cancer Patient in Morocco by Hind Mimouni, Khalid Hassouni, Boujemaa El Marnissi, Bouchra Haddou Rahou, Leila Alaoui, Rachid Ismaili, Abderraouf Hilali, Leila Loukili, Rachid Bekkali, Ahmed Nejmeddine

“…The dominant age group was 35–44, the median patient delay (PD) was 6 days, the median healthcare provider’s delay (HCP) was 21 days, the median referral delay (RD) was 17 days, the median diagnostic delay (DD) was 9.5 days, the median total diagnostic delay (TDD) was 16 days, the median treatment delay (TD) was 67 days, and the median health system interval (HSI) was 92 days. …”
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A Well-Differentiated Liposarcoma with History of Benign Prostatic: A Case Report by Hassan Tavakoli, Hadi Ahmadi Amoli, Seyed Amir Miratashi Yazdi, Mohammad Sharifi, Mina Abdolahi, Mohammad Gholizadeh

“…A 53-year-old male patient presented with lower left quadrant (LLQ) pain and melena for two weeks. Further diagnostic evaluation, including colonoscopy, revealed a 50 mm polyp in the hepatic flexure or distal of the ascending colon. …”
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Computer Tools for Diagnosing Citrus Leaf Symptoms (Part 2): Smartphone Apps for Expert Diagnosis of Citrus Leaf Symptoms by Arnold Schumann, Laura Waldo, Perseveranca Mungofa, Chris Oswalt

“… Visual identification of nutrient deficiencies in foliage is an important diagnostic tool for fine-tuning nutrient management of citrus. …”
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Rectus Abdominis Endometrioma after Caesarean Section by Igor Mishin, Anna Mishina, Sergiu Zaharia, Gheorghe Zastavnitsky

“…We also discuss the diagnostic and treatment particularities in these patients. …”
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Spontaneous and Procedural Plaque Embolisation in Native Coronary Arteries: Pathophysiology, Diagnosis, and Prevention by Giovanni Luigi De Maria, Niket Patel, George Kassimis, Adrian P. Banning

“…This review aims to assess the main aspects of both spontaneous and procedural DE, analyze their different pathophysiology, provide specific insights on the main diagnostic tools for their identification, and finally focus on the main strategies for their treatment and prevention.…”
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Ischemic Colitis in an Endurance Runner by Chase Grames, Cristóbal S. Berry-Cabán

“…This paper describes the pathophysiology, diagnostic approach, and management options.…”
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Pneumonia acquired in the Community by María Caridad Fragoso Marchante, Iris González Morales, Dianelis Sierra Martínez

“…Microorganisms responsible for this type of pneumonia are mention in this paper as well as the available diagnostic methods for germs isolation. Different guidelines for diagnosis and treatment of this disease published by several medical societies and scientific institutions are analyzed by means of a review of the stratification index of the patients used in each of them. …”
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A Rare Complication of Fine-Needle Aspiration of Neck Structures by Yazeed M. Qadadha, Nainika Nanda, Chad Ennis, Timothy McCulloch

“…Fine-needle aspiration (FNA) is a generally accepted tool for safe diagnostic evaluation in the workup of lesions and masses. …”
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Dysphagia Caused by Spindle Cell Lipoma of Hypopharynx: Presentation of Clinical Case and Literature Review by Alberto Peña-Valenzuela, Nathalia García León

“…Here, we present the first case of this lesion originated in the cricopharyngeal region, with symptoms of chronic progressive dysphagia, which can be confused with other pathologies; endoscopic and magnetic resonance imaging (MRI) evaluation are the methods of choice for its diagnostic approach. The best therapeutic approach is endoscopic resection with rapid recovery and few complications. …”
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Unsedated Transnasal Endoscopy: A Canadian Experience in Daily Practice by Sarah Cho, Naveen Arya, Katherine Swan, Maria Cirocco, Gabor Kandel, Paul Kortan, Norman Marcon

“…BACKGROUND: Esophagogastroduodenoscopy (EGD) is the most frequently performed diagnostic procedure for upper gastrointestinal disorders. …”
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Computer Tools for Diagnosing Citrus Leaf Symptoms (Part 2): Smartphone Apps for Expert Diagnosis of Citrus Leaf Symptoms by Arnold Schumann, Laura Waldo, Perseveranca Mungofa, Chris Oswalt

“… Visual identification of nutrient deficiencies in foliage is an important diagnostic tool for fine-tuning nutrient management of citrus. …”
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Use of Directional Spectra for Detection of Engine Cylinder Power Fault by Chong-Won Lee, Yun-Sik Han, Jong-Po Park

“…A diagnostic method, which uses the two-sided directional power spectra of complex-valued engine vibration signals, is presented and tested with four-cylinder compression and spark ignition engines for the diagnosis of cylinder power faults. …”
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Delayed Diagnosis of Iatrogenic Bladder Perforation in a Neonate by Antoinette S. Birs, Jose A. Perez, Mark A. Rich, Hubert S. Swana

“…The following neonatal case report of perforated bladder includes a review of the signs, symptoms, diagnostic tools, and management of bladder injury in neonates.…”
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Cryptogenic Multifocal Ulcerous Stenosing Enteritis: A Review of the Literature by Darina Kohoutová, Jolana Bártová, Ilja Tachecí, Stanislav Rejchrt, Rudolf Repák, Marcela Kopáčová, Jan Bureš

“…Deep enteroscopy enables precise diagnostic work, possible endoscopic treatment of stenoses; may obviate the need for surgery and prevent excessive small bowel resections.…”
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Susceptibility of Clinical Moraxella catarrhalis Isolates in British Columbia to Six Empirically Prescribed Antibiotic Agents by Tamara Bandet, Sue Whitehead, Edith Blondel-Hill, Ken Wagner, Naowarat Cheeptham

“…Susceptibility testing of M catarrhalis is not routinely performed in most diagnostic laboratories; rather, a comment predicting susceptibility based on the literature is attached to the report. …”
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