Protocol for Rhapsody: a longitudinal observational study examining the feasibility of speech phenotyping for remote assessment of neurodegenerative and psychiatric disorders by Allan H Young, Rebecca Strawbridge, Ammar Al-Chalabi, Dag Aarsland, Aleksandra Podlewska, Ray Chaudhuri, Elliot Hampsey, Marton Meszaros, Caroline Skirrow, Rosie H Taylor, Lazarus Chok, Jack Weston, Emil Fristed, Olabisi Awogbemila

“…New, remotely delivered diagnostic assessments that can detect early stage NPDs by profiling speech could enable earlier intervention and fewer missed diagnoses. …”
Get full text

Performance of artificial intelligence on cervical vertebral maturation assessment: a systematic review and meta-analysis by Termeh Sarrafan Sadeghi, Seyed AmirHossein Ourang, Fatemeh Sohrabniya, Soroush Sadr, Parnian Shobeiri, Saeed Reza Motamedian

“…Quality assessment was done using Quality assessment and diagnostic accuracy Tool-2 (QUADAS-2). Quantitative analysis was conducted using hierarchical logistic regression for meta-analysis on diagnostic accuracy. …”
Get full text

Construction of nomogram model based on contrast-enhanced ultrasound parameters to predict the degree of pathological differentiation of hepatocellular carcinoma by Shu-Min Lian, Hong-Jing Cheng, Hong-Jing Li, Hui Wang

“…The prediction model was constructed by logistic regression in the training set, and the final model included three variables: mTTI, FT, and maximum diameter of a single lesion, resulting in the equation was Y=−2.360+1.674X1+1.019X2+0.753X3(2)+1.570X3(3).The area under the ROC curve (AUC) of the training set was 0.831, with a sensitivity of 82.0% and a specificity of 79.5%; the area under the ROC curve (AUC) of the testing set was 0.811, with a sensitivity of 81.0% and a specificity of 70.0%.ConclusionThe regression model constructed by combining multiple parameters can effectively improve the diagnostic performance of CEUS in predicting the pathological differentiation grade of HCC, thus providing a clinical basis and empirical support for the use of CEUS as a diagnostic imaging method for this disease.…”
Get full text

Caprini score combined with thrombotic molecular markers for predicting DVT in patients with traumatic fractures by Zhengsheng Wu, Yaoqiang Du, Xiaofeng Cai, Qian Xu

“…The combined diagnostic efficacy of the postoperative Caprini score and PIC also showed statistical significance (AUC = 0.869, P < 0.001). …”
Get full text

Preoperative prediction of multiple biological characteristics in colorectal cancer using MRI and machine learning by Qiao-yi Huang, Hui-da Zheng, Bin Xiong, Qi-ming Huang, Kai Ye, Shu Lin, Jian-hua Xu

“…Colorectal cancer (CRC) is the second most prevalent cause of oncological mortality, and its diagnostic and therapeutic decision-making processes is complex. …”
Get full text

Small Magnets, Big Future: Low-Field MRI Technology and Clinical Utility by Mohamamdreza Elhaie, Abolfazl Koozari, Iraj Abedi, Mahmoud Mohammadi-Sadr, Abbas Monsef

“…The reduced costs and accessibility afforded by low-field designs have positioned this technology to increase diagnostic MRI access globally. However, further validation of diagnostic performance and cost-utility analyses accounting for accuracy are still needed. …”
Get full text

Investigating the relationship between inflammatory cytokines and adolescent depression: a comparative analysis by Mengqi Liu, Mengqi Liu, Jie Tang, Jie Tang, Gaoyang Xu, Gaoyang Xu, Xu Chen, Xu Chen, Kun Fang, Fan He, Fan He, Yi Zheng, Yi Zheng

“…Cytokines may have promising diagnostic value in adolescent depression, but further validation with additional indicators is needed.…”
Get full text

Bayesian Estimation of the True Bovine Brucellosis Prevalence in Vaccinated and Non-Vaccinated Ecuadorian Cattle Populations, and the Sensitivity and Specificity of a Competitive a... by Ana Dolores Garrido Haro, Margoth Yolanda Barrionuevo Samaniego, Paola Moreno-Caballeros, Alexandra Burbano-Enríquez, Verónica Alexandra Salas Torres, María Cristina Galante Mulki, Constance Wielick, Jorge Ron-Román, Claude Saegerman

“…As serology is a convenient method for detecting antibodies against <i>Brucella</i>, evaluating the diagnostic performance and discriminative ability of such tests in various epidemiological settings is required. …”
Get full text

Accuracy of Lung Ultrasonography for Diagnosis of Heart Failure; a Systematic Review and Meta-analysis by Erfan Rahmani, Masoud Farrokhi, Mehrdad Farrokhi, Shadi Nouri, Atousa Moghadam Fard, Behnam Hoorshad, Ramin Atighi, Erfan Ghadirzadeh, Michael Tajik, Habibollah Afshang, Aida Naseri, Mohadeseh Asoudehfard, Shiva Samami Kojidi, Arsham Ebnemehdi, Mehdi Rezaei, Maziar Daneshvar, Amirali Makhmalbaf, Sepideh Hassanpour Khodaei, Shirin Farsi, Saber Barazandeh Rad, Fateme Nozari, Pouya Rezaei, Negar Babapour, Salman Delavar, Babak Goodarzy, Lida Zare Lahijan, Sanam Mohammadzadeh, Helena Mehran, Fatemeh Gheibi, Ramtin Shemshadigolafzani, Behnaz Dalvandi, Amir Abderam

“…This study aimed to assess the diagnostic performance of lung ultrasonography (LUS) for the identification of acute heart failure in patients with suggestive manifestations. …”
Get full text

Exploring the Pathophysiology, Diagnosis, and Treatment Options of Multiple Sclerosis by Simone Lorenzut, Ilaria Del Negro, Giada Pauletto, Lorenzo Verriello, Leopoldo Spadea, Carlo Salati, Mutali Musa, Caterina Gagliano, Marco Zeppieri

“…This study concludes by highlighting the complexity of multiple MS, including its changing therapeutic landscape, diagnostic problems, and neurophysiological foundations. …”
Get full text

Real-world clinical utility of Xpert MTB/RIF Ultra in the assessment of tuberculosis in a low-TB-incidence, high-resource setting by Robert C Free, Manish Pareek, Hemu Patel, Pranabashis Haldar, Jee Whang Kim, Richard Halliwell, Nelun Perera, Gerrit Woltmann, Alison Glimour-Caunt, Raman Verma

“…Diagnostic sensitivity and specificity were calculated using positive MTB culture and clinical TB diagnosis as reference standards. …”
Get full text

Transient Elastography for Significant Liver Fibrosis and Cirrhosis in Chronic Hepatitis B: A Meta-Analysis by Xiaolong Qi, Min An, Tongwei Wu, Deke Jiang, Mengyun Peng, Weidong Wang, Jing Wang, Chunqing Zhang, on behalf of the CHESS Study Group

“…We performed the meta-analysis describing diagnostic accuracy of transient elastography (TE) for predicting CHB-related fibrosis. …”
Get full text

General practitioner use of D-dimer in suspected venous thromboembolism: historical cohort study in one geographical region in the Netherlands by Angel M R Schols, Eline Meijs, Geert-Jan Dinant, Henri E J H Stoffers, Mariëlle M E Krekels, Jochen W L Cals

“…Objectives To investigate how many general practitioner (GP)-referred venous thromboembolic events (VTEs) are diagnosed during 1 year in one geographical region and to investigate the (urgent) referral pathway of VTE diagnoses, including the role of laboratory D-dimer testing.Design Historical cohort study.Setting GP patients of 47 general practices in a demarcated geographical region of 161 503 inhabitants in the Netherlands.Participants We analysed all 895 primary care patients in whom either the GP determined a D-dimer value or who had a diagnostic work-up for suspected VTE in a non-academic hospital during 2015.Primary and secondary outcome measures The primary outcomes of this study were the total number of VTEs per year and the diagnostic pathways—including the role of GP determined D-dimer testing—of patients urgently referred to secondary care for suspected VTE. …”
Get full text

Ultrasound of the knee in rheumatology by Girish Gandikota

“…With advances in technology, cost reduction, and easy availability, it is expected that more and more clinicians will be utilizing ultrasound in their clinics in management and treatment of rheumatologic diseases. The diagnostic ability of MSK ultrasound is based on an operator's training and experience, the patient's habitus and aptly chosen clinical indications. …”
Get full text

An Approach to Fault Diagnosis for Gearbox Based on Image Processing by Yang Wang, Yujie Cheng

“…The gearbox is one of the most important parts of mechanical equipment and plays a significant role in many industrial applications. A fault diagnostic of rotating machinery has attracted attention for its significance in preventing catastrophic accidents and beneficially guaranteeing sufficient maintenance. …”
Get full text

Imaging Diagnosis of Interstitial Pneumonia with Emphysema (Combined Pulmonary Fibrosis and Emphysema) by Fumikazu Sakai, Junya Tominaga, Akiko Kaga, Yutaka Usui, Minoru Kanazawa, Takashi Ogura, Noriyo Yanagawa, Tamiko Takemura

Get full text

Novel Approaches to Diagnose COVID-19 by Solaf Jawhar Ali

“…Public health agencies are in need of developing diagnostic tools which will have a major impact in tracking the virus and suppressing the transmission. …”
Get full text

Celiac trunk angiography with balloon occlusion of splenic artery for diagnosis and treatment of splenic steal syndrome by Jocelyn Wu, MD, Justin Kim, BS, Kwabena Yamoah, MD, Lealem Aderie, BA, Nariman Nezami, MD, Adam Fang, MD

Get full text

Echocardiography diagnosis of myocardial infarction complications by N.D. Oryshchyn

“…Echocardiography is a main diagnostic method. Analysis of literature about contemporary management of mechanical complications of myocardial infarction has been performed, case reports are presented.…”
Get full text

Unusual Case of Superior Vena Cava Syndrome Caused by Intravascular Thyroid Metastasis by Vanesa Varela Pose, María Patricia Fierro Alanis, Anaberta Bermudez Naveira, Oskarina Lourdes Silva Gonzalez, Jorge Fernandez Noya, Urbano Anido Herranz, Rafael Lopez Lopez

“…This case report shows a multidisciplinary approach which helped diagnose a complicated case, where conventional diagnostic methods were not enough.…”
Get full text