The Laboratory Diagnosis of Hepatitis B Virus by Mel Krajden, Gail McNabb, Martin Petric

“…Given the multitude of available tests and the complexity of clinical management, there is a critical need for greater coordination among clinicians, diagnostic laboratory personnel and researchers to define optimal laboratory diagnostic and monitoring assays so that the appropriate tests are used to maximize prevention and optimize treatment outcomes.…”
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Beneficial Effects of Combining Computed Tomography Enteroclysis/Enterography with Capsule Endoscopy for Screening Tumor Lesions in the Small Intestine by Hiroaki Shibata, Shinichi Hashimoto, Kensaku Shimizu, Ryo Kawasato, Tomohiro Shirasawa, Takayuki Yokota, Hideko Onoda, Takeshi Okamoto, Jun Nishikawa, Naofumi Matsunaga, Isao Sakaida

“…The diagnostic accuracy rate was also significantly higher in CTE/CE versus CTE (100% versus 95.9%, P=0.043). …”
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Exploring potential biomarkers for acute myocardial infarction by combining circadian rhythm gene expression and immune cell infiltration by Xiao Yu, Xiaopeng Zhang, Hazrat Bilal, Chang Shi, Lei Sun

“…Abstract Current diagnostic biomarkers for acute myocardial infarction (AMI), such as troponins, often lack specificity, leading to false positives under non-cardiac conditions. …”
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Early peripheral blood gene expression (Cyp4A11 and Cyp2E1) in cases of brain ischemia in addict cases admitted to Benha university hospital by Nashwa E. Ahmed, Amina M. Nagah, Omima R. Mohamed, Ghada Mohamed Mahmoud, Sania K. Elwia

“…This study explores the roles of CYP4A11, CYP2E1, miR-27b, and miR-214-3p in the pathogenesis of stroke and their potential as diagnostic markers in individuals using tramadol and cannabis. …”
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Optimal Molecular Methods in Detecting p190BCR-ABL Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature by Rebecca J. Sonu, Brian A. Jonas, Denis M. Dwyre, Jeffrey P. Gregg, Hooman H. Rashidi

“…In the era of molecular diagnostic medicine and targeted therapy, it is essential to have an understanding of the limitations of molecular assays and to follow a comprehensive diagnostic approach in order to detect common abnormalities and rare variants. …”
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Clinical and Imaging Characteristics of Smear Negative Pulmonary Tuberculosis Patients: A Comparative Study by Alem Alemayehu, Liya Wassie, Sebsib Neway, Samuel Ayele, Abraham Assefa, Kidist Bobosha, Beyene Petros, Rawleigh Howe

“…It has also been a diagnostic dilemma worldwide leading to diagnostic delays and difficulty in monitoring treatment outcomes. …”
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ANCA-Associated Vasculitic Neuropathy: A Case Report by M. Jakiševaitė, I. Navickaitė, G. Žemgulytė

“…Moreover, the only definitive diagnostic method for VN is peripheral nerve biopsy. …”
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Investigating causal relationships between plasma proteins and lung adenocarcinoma: result from proteomics and Mendelian randomization study by Ruoya Lv, Jiabin Chen, Xiaoyu Wu, Kequn Chai, Jiadong Yan, Sheng Wang

“…The AUC of this diagnostic model was 0.858. Conclusion Plasma IL20RB and SAA2 levels were closely connected with LUAD.…”
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Recognition of Depression and Anxiety among Elderly Colorectal Cancer Patients by Amy Y. Zhang, Gregory S. Cooper

“…The Seer-Medicare data, representing 14–25% of the U.S. population, was used to examine ICD-9 diagnostic rates of depressive and anxiety disorders among 56,182 colorectal cancer outpatients and 265,382 noncancer outpatients, respectively. …”
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Multivariate Analysis of the Ocular Response Analyzer’s Corneal Deformation Response Curve for Early Keratoconus Detection by Jonatán D. Galletti, Pablo R. Ruiseñor Vázquez, Fernando Fuentes Bonthoux, Tomás Pförtner, Jeremías G. Galletti

“…Main outcome measures were corneal-thickness-corrected corneal resistance factor (ccCRF), combinations of corneal descriptors, and their diagnostic performance. Results. Thirty-seven descriptors differed significantly in means between groups, and among them ccCRF afforded the highest individual diagnostic performance. …”
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Quantification of Free Circulating DNA and Differential Methylation Profiling of Selected Genes as Novel Non-Invasive Biomarkers for Endometriosis Diagnosis by Moncef Benkhalifa, Pierre Alain Menoud, David Piquemal, Jack Y. Hazout, Sami Mahjoub, Mohammed Zarquaoui, Noureddine Louanjli, Rosalie Cabry, Andre Hazout

“…Despite decades of research, full pathophysiology, a diagnostic roadmap, and clinical management strategies for endometriosis are not yet fully elucidated. …”
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Microbial and Inflammatory Salivary Biomarkers of Periodontal Diseases by Aram Mohammed Sha, Hayder Raad Abdulbaqi, Syed Saad Bin Qasim

“…The most up to date studies examining the microbial and inflammatory biomarkers with both diagnostic and prognostic values in saliva were reviewed for the purpose of this study.  …”
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Integrating electrocardiogram and fundus images for early detection of cardiovascular diseases by K. A. Muthukumar, Dhruva Nandi, Priya Ranjan, Krithika Ramachandran, Shiny PJ, Anirban Ghosh, Ashwini M, Aiswaryah Radhakrishnan, V. E. Dhandapani, Rajiv Janardhanan

“…Abstract Cardiovascular diseases (CVD) are a predominant health concern globally, emphasizing the need for advanced diagnostic techniques. In our research, we present an avant-garde methodology that synergistically integrates ECG readings and retinal fundus images to facilitate the early disease tagging as well as triaging of the CVDs in the order of disease priority. …”
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Cardiac Transthyretin Amyloidosis: Hidden in Plain Sight by Constantine N. Logothetis, Joel Fernandez, Damian A. Laber

“…This vignette provides an example of the clinical presentation, diagnostic work-up, and treatment of a patient with cardiac transthyretin amyloidosis. …”
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Intracranial Aneurysms Treated with a Novel Coated Low-Profile Flow Diverter (p48 HPC)—A Single-Center Experience and an Illustrative Case Series by Nadja Krug, Jan S. Kirschke, Christian Maegerlein, Kornelia Kreiser, Maria Wostrack, Bernhard Meyer, Carolin Albrecht, Claus Zimmer, Tobias Boeckh-Behrens, Dominik Sepp

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Whole Exome Sequencing Uncovers Germline Variants of Cancer-Related Genes in Sporadic Pheochromocytoma by Milena Urbini, Margherita Nannini, Annalisa Astolfi, Valentina Indio, Valentina Vicennati, Matilde De Luca, Giuseppe Tarantino, Federica Corso, Maristella Saponara, Lidia Gatto, Donatella Santini, Guido Di Dalmazi, Uberto Pagotto, Renato Pasquali, Andrea Pession, Guido Biasco, Maria A. Pantaleo

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Deep learning reconstruction of zero-echo time sequences to improve visualization of osseous structures and associated pathologies in MRI of cervical spine by Malwina Kaniewska, Fabio Zecca, Carina Obermüller, Falko Ensle, Eva Deininger-Czermak, Maelene Lohezic, Roman Guggenberger

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Smartphone Photography as a Teledentistry Method to Evaluate Anterior Composite Restorations by Haleh Valizadeh-Haghi, Safa Valizadeh-Haghi, Nasim Naslseraji, Hamed Zandian

“…Sensitivity, specificity, positive and negative predictive values, and diagnostic accuracy of the photographic method relative to face-to-face method were calculated. …”
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Unusual presentation of secondary CNS lymphoma with punctate intralesional and intraventricular hemorrhage by Daniel De-Liang Loh, Ira Sun, Shiong Wen Low, Pin Lin Kei

“…Primary and secondary central nervous system lymphomas are infrequently encountered entities that present nonspecifically for which imaging plays a critical role in the diagnostic process. The conventional wisdom is that the presence of intralesional hemorrhage in an immunocompetent patient strongly counts against the diagnosis of lymphoma; however more recent evidence suggests that the distinction is more nuanced. …”
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Magnetic Apposition across the Epiglottis: Radiographic and Operative Correlation of a Rare Hypopharyngeal Foreign Body by Yeli Pi, Shilpa Radhakrishnan, Yaser Alrajhi, Ravi Bhargava

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