Diagnostic value and safety of contact laser-assisted endobronchial ultrasound-guided tunnel drilling biopsy in mediastinal and hilar lymphadenopathy: a retrospective study by Wenyu Zhan, Tian Wang, Changqing Yang, Yubao Wang, Nansheng Wan, Jing Feng

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It depends on how you tell: a qualitative diagnostic analysis of the implementation climate for community-wide mass drug administration for soil-transmitted helminth by Judd L Walson, Saravanakumar Puthupalayam Kaliappan, Sitara Swarna Rao Ajjampur, Sarah Lawrence, Khumbo Kalua, Euripide Avokpaho, Amy Roll, Angelin Titus, Yesudoss Jacob, Marie Claire Gwayi-Chore, Félicien Chabi, Comlanvi Innocent Togbevi, Abiguel Belou Elijan, Providence Nindi, Moudachirou Ibikounle, Kumudha Aruldas, Arianna Rubin Means

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A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi. by Bum Ju Park, Sang Taek Heo, Misun Kim, Jeong Rae Yoo, Eun Jin Bae, Su Yeon Kang, Sunghoon Park, Kyeo Re Han, Keun Hwa Lee, Jae Myun Lee, Hyeyoung Lee, Yoon-Jae Song

“…Here, we developed a CRISPR-Cas12a-based diagnostic method targeting the bacterial 16S rRNA to detect O. tsutsugamushi infection of all known genotypes. …”
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Assessing the diagnostic accuracy of radiological and histological findings in the diagnosis of non-alcoholic fatty liver disease stages among patients in a tertiary hospital by Ekpe Edemekong L, Emanghe U, Ekpe EL, Obiora IC, Yemiode Itam, Akinmola OO

“…Aim and Objectives: To evaluate the diagnostic strength of ultrasound in the diagnosis of Non-alcoholic Fatty Liver Disease (NAFLD) stages. …”
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Evaluating Malaria Prevalence Using Clinical Diagnosis Compared with Microscopy and Rapid Diagnostic Tests in a Tertiary Healthcare Facility in Rivers State, Nigeria by M. N. Wogu, F. O. Nduka

“…Values of 47.2%, 95.9%, and 77.8% were obtained for sensitivity, specificity, and diagnostic accuracy, respectively, in clinical diagnosis, while RDTs had sensitivity, specificity, and diagnostic accuracy values of 73.7%, 97.3%, and 88.3%, respectively, when compared to microscopy (P<0.05). …”
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The Prevalence and Diagnostic Ratio of Familial Hypercholesterolemia (FH) and Proportion of Acute Coronary Syndrome in Japanese FH Patients in a Healthcare Record Database Study by Tamio Teramoto, Tomohiro Sawa, Satoshi Iimuro, Hyoe Inomata, Takashi Koshimizu, Iori Sakakibara, Katsutoshi Hiramatsu

“…In Japan, there are few reports on the prevalence and diagnostic ratios of FH and the proportion of ACS among FH patients in clinical settings. …”
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Feasibility of Screening Primary Aldosteronism by Aldosterone-to-Direct Renin Concentration Ratio Derived from Chemiluminescent Immunoassay Measurement: Diagnostic Accuracy and Cutoff Value by Tianqi Li, Yeshuo Ma, Ying Zhang, Yue Liu, Tingting Fu, Ri Zhang, Kai Kang, Yingchao Yang, Lixin Wang, Yinong Jiang, Yan Lu

“…The purpose of the present study was to estimate the diagnostic accuracy and cutoff value of ADRR as screening test for PA. …”
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Diagnostic Accuracy of EndoFaster® and Narrow-Band Imaging Endoscopy in Patients with Impaired Gastric Acid Secretion: A Real-Time Prospective Study by M. Cazzato, G. Esposito, G. Galli, E. Pilozzi, E. Lahner, V. D. Corleto, A. Zullo, E. Di Giulio, B. Annibale

“…Aims. To compare the diagnostic accuracy of EndoFaster® with histological evaluation for corpus atrophic gastritis through high-resolution (HR) NBI targeted biopsies. …”
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Testing of diagnostic test-systems for detection of antibodies to foot-and-mouth disease virus structural proteins with enzyme-linked immunosorbent assay for their serotype specificity by N. N. Lugovskaya, E. A. Silanteva, T. V. Okovytaya, A. A. Kharitonova, Y. M. Gochmuradov, E. A. Razgulyaeva, O. O. Budina, E. A. Yasneva

“…A total of 138 serum samples from pigs and cattle vaccinated against foot-and-mouth disease virus (FMDV) of one or two serotypes or infected with FMDV were used for testing of 24 enzyme-linked immunosorbent assay (ELISA) diagnostic tests-systems for detection of antibodies against FMDV structural proteins produced by 6 manufacturers (Federal Centre for Animal Health, Prionics, IZSLER, Innovative Diagnostics, BIONOTE and MEDIAN Diagnostics) for their serotype-specificity. …”
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Adult Nephroblastoma with Predominant Epithelial Component: A Differential Diagnostic Candidate of Papillary Renal Cell Carcinoma and Metanephric Adenoma—Report of Three Cases by Shiho Watanabe, Hiroshi Naganuma, Michio Shimizu, Satoshi Ota, Shin-ichi Murata, Naoki Nihei, Jun Matsushima, Shuji Mikami, Naoto Kuroda, Yoji Nagashima, Yukio Nakatani

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Informing the development of diagnostic criteria for differential diagnosis of alcohol-related cognitive impairment (ARCI) among heavy drinkers: A systematic scoping review. by Lisa Jones, Lynn Owens, Andrew Thompson, Ian Gilmore, Paul Richardson

“…<h4>Results</h4>In total, only 7 studies met our primary objective and reported on modifications to existing definitions or diagnostic criteria for ARCI. These studies revealed a lack of coordinated research and progress towards the development and standardisation of diagnostic criteria for ARCI. …”
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Relationship between Metabolic Syndrome and Ocular Microcirculation Shown by Laser Speckle Flowgraphy in a Hospital Setting Devoted to Sleep Apnea Syndrome Diagnostics by Tomoaki Shiba, Mao Takahashi, Tadashi Matsumoto, Yuichi Hori

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Multivariable Diagnostic Prediction Model to Detect Hormone Secretion Profile From T2W MRI Radiomics with Artificial Neural Networks in Pituitary Adenomas by Begumhan BAYSAL, Mehmet Bilgin ESER, Mahmut Bilal DOGAN, Muhammet Arif KURSUN

“…Outcomes were identified as 7 hormone secretion profiles [non-functioning pituitary adenoma, growth hormone-secreting adenomas, prolactinomas, adrenocorticotropic hormone-secreting adenomas, pluri-hormonal secreting adenomas (PHA), follicle-stimulating hormone and luteinizing hormone-secreting adenomas, and thyroid-stimulating hormone adenomas]. A multivariable diagnostic prediction model was developed with artificial neural networks (ANN) for 7 outcomes. …”
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Rapid diagnostic testing combined with an immediate infectious disease consultation increases the rate of septic intensive care unit patients on targeted antibiotic therapy by Evelyn Kramme, Nadja Käding, Nadja Käding, Tobias Graf, Karolin Schmoll, Heidi Linnen, Katharina Nagel, Esther Grote-Levi, Susanne Hauswaldt, Dennis Nurjadi, Dennis Nurjadi, Jan Rupp, Jan Rupp, Jan Rupp

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A Rare Case of Erdheim-Chester Disease (Non-Langerhans Cell Histiocytosis) with Concurrent Langerhans Cell Histiocytosis: A Diagnostic and Therapeutic Challenge by Hamza Hashmi, Drew Murray, John Greenwell, Marwan Shaikh, Soumit Basu, Maxwell Krem

“…We present a rare case of Erdheim-Chester disease with concurrent Langerhans cell histiocytosis which occurs in only one fifth of the cases and often presents as a diagnostic and therapeutic challenge.…”
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Real-world smartphone-based point-of-care diagnostics in primary health care to monitor HbA1c levels in people with diabetes by Sabrina Rhode, Lisa Rogge, Marthoenis Marthoenis, Till Seuring, Hendra Zufry, Till Bärnighausen, Hizir Sofyan, Jennifer Manne-Goehler, Sebastian Vollmer

“…This method could provide access to high-quality diagnostic decisions through regular and cost-effective HbA1c monitoring directly in healthcare facilities, thus providing better access to essential health services.…”
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Palmitoylation-related gene ZDHHC22 as a potential diagnostic and immunomodulatory target in Alzheimer’s disease: insights from machine learning analyses and WGCNA by Sanying Mao, Xiyao Zhao, Lei Wang, Yilong Man, Kaiyuan Li

“…This study applied WGCNA along with three machine learning algorithms—random forest, LASSO regression, and SVM–RFE—to further select key PRGs (KPRGs). The diagnostic performance of KPRGs was evaluated using Receiver Operating Characteristic (ROC) curve analysis. …”
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Perioperative infarction during coronary bypass surgery: an attempt to refine the diagnostic criteria using data from a retrospective case–control study by Lars Niclauss, Liam-Kani Roulet, Piergiorgio Tozzi, Filip Dulguerov, Ziyad Gunga, Anna Nowacka, Matthias Kirsch

“…An enzyme activity increase alone is of limited diagnostic value for perioperative MI, which is associated with greater mortality. …”
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Inactivation of SARS-CoV-2 virus in saliva using a guanidium based transport medium suitable for RT-PCR diagnostic assays. by Sukalyani Banik, Kaheerman Saibire, Shraddha Suryavanshi, Glenn Johns, Soumitesh Chakravorty, Robert Kwiatkowski, David Alland, Padmapriya P Banada

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A Case of Torsion in an Otherwise-Normal Ovary with a Giant Hematosalpinx Larger than Enlarged Ovary: Utilization of Diagnostic Laparoscopy for the Accurate Diagnosis by Sae Yu, Koji Yamanoi, Masumi Sunada, Sachiko Kitamura, Naoki Horikawa, Yoshitsugu Chigusa, Ken Yamaguchi, Akihito Horie, Junzo Hamanishi, Eiji Kondoh, Masaki Mandai

“…Three days later, she came back with increased symptoms, and we detected the mass of a complex solid cystic structure with a unilocular cyst much larger than solid component. A diagnostic laparoscopy was performed immediately, and we could make a diagnosis of torsion in an otherwise-normal ovary with a giant hematosalpinx. …”
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