The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis by Zhihui Xu, Cong Liu, Peng Wang, Xing Wang, Yuzhang Li

“…Conclusion Based on the International Classification of Diseases (ICD) and the Diagnostic and Statistical Manual of Mental Disorders (DSM) classification systems, a research framework for exercise interventions on executive function in MDD patients was constructed, demonstrating that exercise can improve inhibitory function in MDD with high evidence quality. …”
Get full text

DEVELOPING INFORMATION AND TECHNOLOGICAL COMPETENCE OF PROSPECTIVE MILITARY SAILORS by Ruslan Shevchenko, Oleh Cherniavskyi, Vasyl Shemchuk, Olena Zlobina, Natalia Benkovska, Nataliia Terentieva, Андрій Гуралюк

“…With the help of a comparative analysis based on the results of two diagnostic sections, the statistical reliability of the differences in the signs of identifying IT competence criteria before and after the training of future officers of the Ukrainian Navy was determined Considering the unique dynamics within a maritime institution of higher education, a systematic blend of lectures, discussions, practical training sessions, situational exercises, utilization of virtual technologies, and the undertaking of group and individual projects significantly elevated the level of information technology competence among future Naval Forces officers. …”
Get full text

Genetic insights into MIS-C Post-COVID-19 in Kuwaiti children: investigating monogenic factors by Mohammed Dashti, Hessa AlKandari, Hessa AlKandari, Md Zubbair Malik, Rasheeba Nizam, Sumi Elsa John, Sindhu Jacob, Arshad Channanath, Fouzeyah Othman, Safa Al-Sayed, Osama Al-Hindi, Mona Al-Mutari, Thangavel Alphonse Thanaraj, Fahd Al-Mulla

“…The findings highlight the critical role of genetic predispositions in MIS-C and suggest that further functional genomics work is necessary to explore the mechanistic contributions of these genes, facilitating the development of targeted diagnostic strategies.…”
Get full text

Diagnosis and genomic characterization of the largest western equine encephalitis virus outbreak in Uruguay during 2023–2024 by Gonzalo Tomás, Ana Marandino, Sirley Rodríguez, Gabriel Luz Wallau, Filipe Zimmer Dezordi, André Luiz Sá de Oliveira, Claudia Techera, Lucía Calleros, Sofía Grecco, Joaquín Williman, Ramiro Pérez, Lucía Bassetti, Raúl Negro, Lucía Moreira Marrero, Adriana Delfraro, Roberto Vidal, Yanina Panzera, Ruben Pérez

“…Genomic analysis also revealed mispairing in real-time PCR primers and probes that may affect official diagnostic protocols.…”
Get full text

Investigation of 23 Bile Acids in Liver Bile in Benign and Malignant Biliary Stenosis: A Pilot Study by Stanislav Rejchrt, Milos Hroch, Rudolf Repak, Tomas Fejfar, Tomas Douda, Darina Kohoutova, Eva Peterova, Jan Bures

“…More patients need to be enrolled in further studies so that the real diagnostic yield of bile acids can be determined.…”
Get full text

The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…The correlation between hematological indicators and tumor-node-metastasis (TNM) stage was assessed through Spearman’s analysis.Results: Eligible patients and healthy controls were grouped by gender. The diagnostic ability of PNI was significantly superior to other indicators to diagnose male GC (area under the curve [AUC]=0.908, 95% CI: 0.892– 0.925) and female GC (AUC=0.890, 95% CI: 0.865– 0.914). …”
Get full text

Early diagnosis and the effect of treatment compliance on the prognosis and progression of glaucomatous optic neuropathy by S.V. Diordiychuk, A.V. Kuroyedov, N.E. Fomin, O.V. Gapon’ko, V.V. Gorodnichiy, I.V. Kondrakova, N.M. Sol’nov

“…The specificity of this case report is a long-term observation period at one hospital and the use of standardized diagnostic tools. Moreover, dynamic monitoring was performed using the same devices to assess structural and functional alterations of the retina and optic nerve. …”
Get full text

Health Economic Evaluation of Patients With Colorectal Liver Metastases Randomized to ALPPS or TSH: Analysis From the LIGRO Trial by Kristina Hasselgren, MD, PhD, Martin Henriksson, PhD, Bård I. Røsok, MD, PhD, Peter N. Larsen, MD, PhD, Ernesto Sparrelid, MD, PhD, Gert Lindell, MD, PhD, Nicolai A. Schultz, MD, PhD, Bjorn A. Bjørnbeth, MD, PhD, Bengt Isaksson, MD, PhD, Magnus Rizell, MD, PhD, Anna Lindhoff Larsson, RN, Per Sandström, MD, PhD, Bergthor Björnsson, MD, PhD

“…Costs are estimated from resource use, including all surgical interventions, length of stay after interventions, diagnostic procedures and chemotherapy, and applying Swedish unit costs. …”
Get full text

Single or multiple treatments with lusutrombopag in subjects with thrombocytopenia and chronic liver disease needing an invasive procedure by Davide Scalabrini, Paolo Sciuto, Cristina Felicani, Antonia Rudilosso, Pietro Andreone

“…This condition, when present in the severe form [platelet count (PLT) less than 50 × 109/L] correlates, with an increased risk of bleeding during the main diagnostic-therapeutic procedures which cirrhotic patients usually undergone. …”
Get full text

Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma by Masahiro Nishikawa, Akihiro Inoue, Takanori Ohnishi, Shohei Kohno, Shiro Ohue, Shirabe Matsumoto, Satoshi Suehiro, Daisuke Yamashita, Saya Ozaki, Hideaki Watanabe, Hajime Yano, Hisaaki Takahashi, Riko Kitazawa, Junya Tanaka, Takeharu Kunieda

Get full text

Characteristics of visual functions and their correlation with OCT-angiography of the macula in patients with small choroidal melanoma by Е.Б. Мякошина, S.V. Saakyan

“…</p> <p> <b>Conclusion</b>: the characterization of visual functions and their correlation with ophthalmoscopy is important for identifying the first signs of choroidal melanoma development.The assessment of OCT-A findings is a unique diagnostic criterion enabling to detect the first signs of macular microvascular disorders accompanying the manifestation and growth of extramacular choroidal melanoma. …”
Get full text

Clinical assessment of urinary prostate cancer antigen 3 in Chinese population: a large-scale, prospective and multicenter study by Xuan Shu, Jiaming Wang, Wen Cai, Shen Lin, Jiangfeng Li, Xueyou Ma, Yufan Ying, Yat Sai Terry Wang, Xiao Wang, Hong Chen, Chunyu Jin, Ben Liu, Liping Xie, Jindan Luo

“…Abstract Background To assess the clinical utility of PCA3 in the diagnostic accuracy, the correlation between PCA3 and biopsy or pathological characteristics and the performance of PCA3 to reduce the unnecessary biopsies in Chinese population. …”
Get full text

Molecular characterization and lineage analysis of canine astrovirus strains from dogs with gastrointestinal disease in Ecuador based on ORF-2 gene analysis by Anthony Loor-Giler, Anthony Loor-Giler, Silvana Santander-Parra, Sara Castillo-Reyes, Martín Campos, Martín Campos, Renan Mena-Perez, Renan Mena-Perez, Santiago Prado-Chiriboga, Santiago Prado-Chiriboga, Luis Nunez, Luis Nunez

“…Given the high frequency of CaAstV infections in dogs with gastroenteritis and its high genetic variability, it emphasizes the need to implement routine diagnostic measures that include this pathogen as one of the main causes of the disease and a risk agent in case of multiple infections.…”
Get full text

Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B or C by Contrast-Enhanced Magnetic Resonance Imaging by René Hako, Pavol Kristian, Peter Jarčuška, Ivana Haková, Ivana Hockicková, Ivan Schréter, Martin Janičko

“…Gd-EOB-DTPA contrast-enhanced dynamic liver MRI examination (DCE-MRI) can in the 20th minute differentiate mild stage of liver fibrosis (F1-F2) from severe stage of liver fibrosis (F3-F4) on the basis of liver surface changes, homogeneities, and quantitative contrast liver/spleen ratio-Q-LSCR. Diagnostic MRI criteria were created and named MRI Triple test. …”
Get full text

Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer by Zhiheng Lin, Fengxin Wang, Renwu Yin, Shengnan Li, Yuquan Bai, Baofang Zhang, Chenlin Sui, Hengjie Cao, Dune Su, Lianwei Xu, Honghong Wang

“…The validation of PLOD2 as a prognostic gene highlights its therapeutic potential, underscoring the critical need for integrating immunotherapy and targeted treatment strategies to enhance diagnostic and therapeutic approaches in cervical cancer.…”
Get full text

P53 and Expression of Immunological Markers May Identify Early Stage Thyroid Tumors by Marjory Alana Marcello, Elaine Cristina Morari, Lucas Leite Cunha, Aline Carolina De Nadai Silva, Dirce Maria Carraro, André Lopes Carvalho, Fernando Augusto Soares, José Vassallo, Laura Sterian Ward

“…We aimed to investigate p53 and immune cell markers utility as diagnostic and prognostic markers of differentiated thyroid cancer (DTC). …”
Get full text

Accuracy of noninvasive total haemoglobin measurement for detecting anaemia in infants: a cross-sectional study in a well-child care clinic, Khon Kaen, Thailand by Leelawadee Techasatian, Rattapon Uppala, Suchaorn Saengnipanthkul, Chamaiporn Tawiangnan, Prapassara Sirikarn, Sakuntala Supasai, Phanthila Sitthikarnkha

“…Depending on the context and available resources, it has potential to complement existing diagnostic processes, particularly in settings where rapid and noninvasive screening is prioritised.Trial registration number Thai Clinical Trials Registry (TCTR20210816002).…”
Get full text

Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus by Saowanee Chamnanya, Benyapa Kiddela, Jassada Saingamsook, Woottichai Nachaiwieng, Nongkran Lumjuan, Pradya Somboon, Jintana Yanola

Get full text

Knee phenotypes distribution according to CPAK classification in Turkish population by Vahit Emre Özden, Göksel Dikmen, Kayahan Karaytuğ, Arda Mavi, Yılmaz Onat Köylüoğlu, İsmail Remzi Tözün

“…Level of Evidence: Level III, Diagnostic Study…”
Get full text

Comparison of self-collected and healthcare worker-collected rectovaginal swabs for group B streptococcus detection in pregnancy using PCR with a commercial collection-enrichment d... by Iva Kukovica, Neža Omahen, Nika Klobučar, Martina Bučar, Anita Franko Rutar, Tina Perme, Tina Perme, Miha Lučovnik, Miha Lučovnik, Samo Jeverica, Samo Jeverica

“…Performance characteristics were calculated and compared between different diagnostics test algorithms using McNemar’s test for paired samples.ResultsOverall, GBS was detected in 18% (95% CI 13–23%; n = 40) of swabs A and 19% (95% CI 14–25%; n = 43) of swabs B. …”
Get full text