Studies of biological properties of continuous suspension ВНК-21/SUSP/ARRIAH cell line by M. I. Doronin, M. N. Guseva, D. V. Mikhalishin, A. S. Sharypov, N. S. Mudrak, N. Ye. Kamalova, B. L. Manin

“…The results of the studies of cytomorphological, karyological, cultural properties of continuous suspension ВНК-21/SUSP/ARRIAH subline of newborn Syrian hamster kidney cells intended for foot-and-mouth disease, rabies, bovine parainfluenza-3, Aujeszky’s disease virus reproduction, as well as for production of diagnostic veterinary biologicals are presented. When cultured in suspension, BHK-21/SUSP/ARRIAH cell subline undergoes selection towards hypoploidy: modal class is represented by cells with 41 chromosomes (32–40% of cells); the share of cells containing 40–42 chromosomes is 78–80%; the share of polyploids averages around 1%; the range of variation in the number of chromosomes is from 36 to 54. …”
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MicroRNA Biomarker hsa-miR-195-5p for Detecting the Risk of Lung Cancer by Lei Li, Tienan Feng, Weituo Zhang, Sumeng Gao, Ruoyang Wang, Wenwen Lv, Tengteng Zhu, Herbert Yu, Biyun Qian

“…Lung cancer is one of the leading diagnosed cancers worldwide, and microRNAs could be used as biomarkers to diagnose lung cancer. hsa-miR-195 has been demonstrated to affect the prognosis of NSCLC (non-small-cell lung cancer) in a previous study. However, the diagnostic value of hsa-miR-195-5p in lung cancer has not been investigated. …”
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Evaluation of Individual Cardiovascular Risk in Pre-Dialysis CKD Patients by Using the Ratio of Calcium–Phosphorus Product to Estimated Glomerular Filtration Rate (Ca × P/eGFR) by Krasimir Kostov, Tatyana Simeonova, Borislav Ignatov, Tsvetelina Eftimova

“…Statistical analyses were performed to identify predictors of CV risk and evaluate the diagnostic reliability of the Ca × P/eGFR ratio for predicting the risk. …”
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Identification of Parkinson’s disease using MRI and genetic data from the PPMI cohort: an improved machine learning fusion approach by Yifeng Yang, Liangyun Hu, Yang Chen, Weidong Gu, Guangwu Lin, YuanZhong Xie, Shengdong Nie

“…Furthermore, by analyzing the features selected across multiple iterations of our models, we identified stable brain region features [lh 6r (FD) and rh 46 (GI)] and key genetic markers (rs356181 and rs2736990 SNPs within the SNCA gene region; rs213202 SNP within the VPS52 gene region), highlighting their potential as reliable early diagnostic indicators for the disease.ConclusionThe AE_Stacking model, trained on MRI and genetic data, demonstrates potential in distinguishing individuals with PD. …”
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Clinical Correlations of Novel Autoantibodies in Patients with Dry Eye by Sezen Karakus, Alan N. Baer, Esen K. Akpek

“…Background. Diagnostic criteria for Sjögren’s syndrome (SS) are continually being updated in pursuit of more precise and earlier diagnosis to prevent its complications. …”
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Novel Models for the Prediction of Left Atrial Appendage Thrombus in Patients with Chronic Nonvalvular Atrial Fibrillation by Do Van Chien, Pham Thai Giang, Pham Truong Son, Le Van Truong, Pham Nguyen Son

“…The following parameters had good diagnostic performance for LAAT: LA volume index >57 mL (area under the curve (AUC), 0.72; sensitivity, 77.1%; specificity, 64.2%), LA positive strain ≤6.7% in the four-chamber view (AUC, 0.84; sensitivity, 77.1%; specificity, 77.1%), and LA negative strain rate >−0.73 s−1 in the four-chamber view (AUC, 0.83; sensitivity, 85.7%; specificity, 70.6%). …”
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Raw Cured Poultry Meat Fortified with Bee Pollen: Biomedical Research on Laboratory Animals by Maksim A. Sukhov, Tatiana M. Giro, Sergey V. Kozlov, Irina V. Ziruk

“…The research involved a MicroCC20Vet analyzer for hematological tests and a StatFax 3300 analyzer with Diacon DS diagnostic systems for biochemical tests. The histological analyses relied on the method developed by G.A. …”
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Linking obesity-associated genotype to child language development: the role of early-life neurology-related proteomics and brain myelinationResearch in context by Jian Huang, Jinyi Che, Michelle Z.L. Kee, Ai Peng Tan, Evelyn C. Law, Patricia Pelufo Silveira, Irina Pokhvisneva, Sachin Patel, Keith M. Godfrey, Lourdes Mary Daniel, Kok Hian Tan, Yap Seng Chong, Shiao-Yng Chan, Johan G. Eriksson, Dennis Wang, Jonathan Yinhao Huang

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Hormonal Influences on ADC Values in Breast Tissues: A Scoping Review of DWI in Pre- and Post-menopausal Women [version 3; peer review: 2 approved] by Neil Barnes Abraham, Abhimanyu Pradhan, Suresh Sukumar, Sneha Ravichandran, Winniecia Dkhar, Rajagopal Kadavigere

“…Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) measurements have emerged as promising tools in breast cancer diagnostics. However, the influence of hormonal status on these measurements remains unclear. …”
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Optimizing injection accuracy for Baxter’s nerve entrapment: an ultrasonography-guided approach based on anatomical surface landmarks by Jung-woo Choi, Hyung-Jin Lee, Yong-Seok Nam, Mi Young Shin, Sang-Hyun Kim, Jun-Ho Kim, In-Beom Kim

“…This study provides anatomical guidelines for optimal transducer placement using two specific landmarks, the most inferior tip of the medial malleolus (A) and the most protruding posterior tip of the calcaneus (B), to enhance the diagnostic and therapeutic injection efficacy for proximal and distal entrapment sites.Materials and Methods Eighty-six feet from 45 fresh cadavers (25 male and 20 female) were dissected to determine Baxter’s nerve (BN) localization. …”
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The prognostic value of circulating tumor DNA in malignant melanoma patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis by Lei Liu, Shufu Hou, Aiping Zhu, Bing Yan, Linchuan Li, Dandan Song

“…Therefore, ctDNA can serve as a diagnostic and stratification tool prior to treatment, as well as an effective indicator for monitoring treatment response and disease progression.Systematic Review Registrationwww.inplasy.com, identifier INPLASY2024110018.…”
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Kidney disease among adults on tenofovir-based second-line antiretroviral therapy in Dar es Salaam, Tanzania by Sabina F. Mugusi, Grace A. Shayo, Philip G. Sasi, Lulu S. Fundikira, Eric A. Aris, Christopher R. Sudfeld, Ferdinand M. Mugusi

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Nailfold Capillaroscopy in Early Stages of Mixed Connective Tissue Disease in a Sample of Egyptian Patients by Yasser A Elmotaleb Gazar, Hesham Salah Hamoud, Sherif Mohamed Ismail

“…Nailfold capillaroscopy (NFC) is a noninvasive diagnostic tool for patients with different connective tissue diseases that permit detection of local microvascular changes that correlate with systemic vascular involvement. …”
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Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome by N. Inayet, J. O. Hayat, A. Kaul, M. Tome, A. Child, A. Poullis

“…Patients with a diagnosis of either MS or hEDS attending cardiology or rheumatology outpatients at our hospital were asked to complete SF36 RAND and Rome IV Diagnostic questionnaires. Questionnaires were also completed by patients who are members of Marfan Association UK. …”
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Older Fallers’ Comprehensive Neuromuscular and Kinematic Alterations in Reactive Balance Control: Indicators of Balance Decline or Compensation? A Pilot Study by Ringo Tang-Long Zhu, Timmi Tim Mei Hung, Freddy Man Hin Lam, Jun-Zhe Li, Yu-Yan Luo, Jingting Sun, Shujun Wang, Christina Zong-Hao Ma

“…A further longitudinal study with a larger sample is still needed to examine the diagnostic accuracies and training values of these identified neuromuscular/kinematic factors in differentiating fall risks and preventing future falls of older people, respectively.…”
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The <i>Meq</i> Genes of Nigerian Marek’s Disease Virus (MDV) Field Isolates Contain Mutations Common to Both European and US High Virulence Strains by Joseph N. Patria, Luka Jwander, Ifeoma Mbachu, Levi Parcells, Brian Ladman, Jakob Trimpert, Benedikt B. Kaufer, Phaedra Tavlarides-Hontz, Mark S. Parcells

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In Silico Screening of Putative Corynebacterium pseudotuberculosis Antigens and Serological Diagnosis for Caseous Lymphadenitis in Sheep by Enzyme-Linked Immunosorbent Assay by Daniela Droppa-Almeida, Caroline de Santana Ferreira, Ioná Brito, Sibele Borsuk, Jorge Alberto López Rodríguez, Isabel Bezerra Lima-Verde, Francine Ferreira Padilha

“…None of the specificity values preclude the potential of rPTS, rRibonuclease, or rCP40 for use in ELISA diagnostic assays since the results of this work are superior to those of other studies on CLA diagnosis described in the literature.…”
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Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms by Jozsef Nagy, Wolfgang Fenz, Stefan Thumfart, Julia Maier, Zoltan Major, Harald Stefanits, Maria Gollwitzer, Johannes Oberndorfer, Nico Stroh, Michael Giretzlehner, Michael Sonnberger, Andreas Gruber, Philip-Rudolf Rauch, Matthias Gmeiner

“…With a threshold of 0.075, the HGD index exhibited excellent diagnostic performance; in internal validation, 24 of 25 ruptured aneurysms surpassed this threshold, yielding a sensitivity of 0.96. …”
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A novel interpretable deep learning model for diagnosis in emergency department dyspnoea patients based on complete data from an entire health care system. by Ellen T Heyman, Awais Ashfaq, Ulf Ekelund, Mattias Ohlsson, Jonas Björk, Ardavan M Khoshnood, Markus Lingman

“…We aimed to design a diagnostic decision support which classifies dyspnoeic ED visits into acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), pneumonia and "other diagnoses" by using deep learning and complete, unselected data from an entire regional health care system.…”
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Unique Case Reports Associated with Ovarian Failure: Necessity of Two Intact X Chromosomes by Lakshmi Rao Kandukuri, Venkata Padmalatha, Murthy Kanakavalli, Raseswari Turlapati, Mangalipally Swapna, Metuku Vidyadhari, Govindaraghavan Saranaya, Kattera Himaja, Mamata Deenadayal, Bipin Kumar Sethi, Prasun Deb, Nalini Gupta, Baidyanath Chakraborthy, Pratibha Nallari, Lalji Singh

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