Autoantibodies in systemic sclerosis: From disease bystanders to pathogenic players by Aurélien Chepy, Aurore Collet, David Launay, Sylvain Dubucquoi, Vincent Sobanski

“…The advancements surrounding Aab provide insights into new disease mechanisms and may lead to innovative diagnostic and treatment approaches.…”
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Hormonal Influences on ADC Values in Breast Tissues: A Scoping Review of DWI in Pre- and Post-menopausal Women [version 2; peer review: 2 approved] by Neil Barnes Abraham, Abhimanyu Pradhan, Suresh Sukumar, Sneha Ravichandran, Winniecia Dkhar, Rajagopal Kadavigere

“…Diffusion-Weighted Imaging (DWI) and Apparent Diffusion Coefficient (ADC) measurements have emerged as promising tools in breast cancer diagnostics. However, the influence of hormonal status on these measurements remains unclear. …”
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A Case of Acquired Reactive Perforating Dermatosis with Complete Resolution of Eruptions on Upper and Lower Limbs During the Treatment of Diabetes Mellitus and Peripheral Artery Di... by Yoshihito Mima, Tsutomu Ohtsuka, Ippei Ebato, Ryosuke Nishie, Satoshi Uesugi, Makoto Sumi, Yoshimasa Nakazato, Yuta Norimatsu

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Diastolic dysfunction evaluation by cardiovascular magnetic resonance derived E, a, e’: Comparison to echocardiography by Jérôme Lamy, Jie Xiang, Nimish Shah, Jennifer M. Kwan, Yekaterina Kim, Krishna Upadhyaya, Samuel W. Reinhardt, Judith Meadows, Robert L. McNamara, Lauren A. Baldassarre, Dana C. Peters

“…Measurements by TTE and CMR were compared using regression. The diagnostic accuracy of CMR for DD was determined.CMR derived E, A, E/A, e’ and E/e’ all correlated moderately to strongly with TTE, and more strongly when comparing studies performed closer in time (E: r = 0.68, E deceleration time: r = 0.82, A: r = 0.78, e’ r = 0.75, E/e’: r = 0.80, p = 0.001; LAVi: r = 0.79, p < 0.001; E/A: r = 0.82, p < 0.001, n = 14 within 45 days). …”
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Quality of life in people with syndromic heritable thoracic aortic disease and their relatives: a qualitative interview based study by Gry Velvin, Heidi Johansen, Gunnbjørg Aune, Kerstin Fugl-Meyer, Amy Østertun Geirdal

“…There was high degree of consensus regarding the factors emphasized as important for QoL among the various diagnostic groups and the relatives. Conclusion Based on our findings, to improve QoL in patients with sHTAD we should more effectively integrate the patient`s perspectives and voice on the elements crucial to QoL. …”
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Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications by Zhenglin He, Yishuo Ji, Yutong Yuan, Tianfang Liang, Chenglin Liu, Yiping Jiao, Yimeng Chen, Yiming Yang, Liang Han, Liang Han, Yue Hu, Yue Hu, Xianling Cong, Xianling Cong, Xianling Cong

“…In this review, we provide a comprehensive analysis of the role of miRNAs in EC, emphasizing their mechanisms in tumorigenesis, their potential as diagnostic and prognostic biomarkers, and their influence on resistance to therapy. …”
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Multifocality and Detectability of Prostate Cancer with 3-Tesla Multiparametric Magnetic Resonance Imaging: Correlation with Radical Prostatectomy Mapping Histopathology by Serdar Karadağ, Deniz Noyan Özlü, Ahmet Hacıislamoğlu, Ömer Yıldız, Halil Fırat Baytekin, Mithat Ekşi, Hakan Polat, Alper Bitkin, Ali İhsan Taşçı

“…Conclusion. mpMRI exhibited an acceptable sensitivity in detecting high-risk and large Pca foci. The diagnostic accuracy is observed to be markedly diminished in small, low GS, and nonindex tumors. …”
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Semi-standardized evaluation of extraprostatic extension and seminal vesicle invasion with [18F]PSMA-1007 PET/CT: a comparison to MRI using histopathology as reference by Erland Hvittfeldt, Fredrik Hedeer, Erik Thimansson, Kevin Sandeman, David Minarik, Jacob Ingvar, Anders Bjartell, Elin Trägårdh

“…A radiologist evaluated MRI images using criteria based on Prostate Imaging–Reporting and Data System version and incorporating LCC measurement and Likert scales. We evaluated diagnostic performance with histopathology as reference, and the interrater reliability of the PET evaluations. …”
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Consistency of the Buss and Perry Aggression Questionnaire in Peruvian female university nursing students by Margarita Córdova-Delgado, Mónica Ayne Guevara-Saravia, Marlene Muñoz-Aguirre, Gladys Marcelina Puza-Mendoza, Alfredo Enrique Oyola-García

“…Introducción: la conducta agresiva forma parte de los trastornos disruptivos del control de impulsos y de la conducta establecidos en The Diagnostic and Statistical Manual of Mental Disorders – Fifth Edition (DSM-V). …”
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Radiation dosimetry performance appraisal of the optimal concentration of nitro blue tetrazolium dye in PVA composite film at low X-ray doses by Reham Albejadi, Saleh Alashrah, Yassine El-Ghoul, Zabih Ullah, Saleh A. Almatroodi

“…Purpose: Due to the extensive use of radiation in various fields, such as food safety, sterilizing surgical materials, and medical diagnostics, it is essential to minimize radiation exposure for both patients and healthcare professionals, even at low doses. …”
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Explainable AI-Based Approach for Age-Related Macular Degeneration (AMD) Detection via Fundus Imaging by Ainhoa Osa-Sanchez, Hossam Magdy Balaha, Ali Mahmoud, Ashraf Sewelam, Mohammed Ghazal, Begonya Garcia-Zapirain, Ayman El-Baz

“…This paper addresses multiple shortcomings in conventional AMD diagnostic techniques by exploring the detection and explanation of various AMD subtypes from numerical features extracted with a ViT model from fundus images through cascaded artificial intelligence (AI) models using transformers, convolutional neural networks (CNNs), and multilayer perceptrons (MLPs). …”
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Prevalence of childhood mental disorders in high-income countries: a systematic review and meta-analysis to inform policymaking by Charlotte Waddell, Christine Schwartz, Jenny Lou Barican, Donna Yung, Yufei Zheng, Katholiki Georgiades

“…Significant heterogeneity pertained to diagnostic measurement and study location. Anxiety (5.2%), attention-deficit/hyperactivity (3.7%), oppositional defiant (3.3%), substance use (2.3%), conduct (1.3%) and depressive (1.3%) disorders were the most common. …”
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Lifestyle as Risk Factor for Infectious Causes of Death in Young Dogs: A Retrospective Study in Southern Italy (2015–2017) by Lorena Cardillo, Giuseppe Piegari, Valentina Iovane, Maurizio Viscardi, Flora Alfano, Anna Cerrone, Ugo Pagnini, Serena Montagnaro, Giorgio Galiero, Giuseppe Pisanelli, Giovanna Fusco

“…A retrospective study was conducted in a 3-year period (2015–2017) on 138 dead dogs that had undergone necropsy and microbiological diagnostics. Enteritis and pneumonia were the most commonly observed lesions. …”
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A novel framework to predict ADHD symptoms using irritability in adolescents and young adults with and without ADHD by Saeedeh Komijani, Dipak Ghosal, Manpreet K. Singh, Julie B. Schweitzer, Julie B. Schweitzer, Prerona Mukherjee, Prerona Mukherjee

“…While irritability is not a diagnostic symptom of ADHD, temper outbursts and irritable moods are common in individuals with ADHD. …”
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Germline Mutation in KIF1Bβ Gene Associated with Loss of Heterozygosity: Usefulness of Next-Generation Sequencing in the Genetic Screening of Patients with Pheochromocytoma by Giuseppina De Filpo, Elisa Contini, Viola Serio, Andrea Valeri, Massimiliano Chetta, Daniele Guasti, Daniele Bani, Massimo Mannelli, Elena Rapizzi, Michaela Luconi, Mario Maggi, Tonino Ercolino, Letizia Canu

“…Our aim is to underline how genetic diagnosis by next-generation sequencing (NGS) can improve the management of patients affected by pheochromocytomas and paragangliomas in our routine diagnostic screening. We reported a case presentation and next-generation sequencing analysis supported by in silico studies and evaluation of mitochondrial status in KIF1Bβ tissue. …”
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Clinical features and outcomes of pseudolithiasis induced by ceftriaxone in Chinese children: a single-center observational study by Chen Jin, Chen Jin, Wen-Li Xiu, Wen-Li Xiu, Yao Liu, Yao Liu, Xi-Wei Hao, Qian Dong, Qian Dong

“…IntroductionCeftriaxone (CTX) is widely used in pediatric infectious disease treatment, although the diagnostic and therapeutic management of CTX-induced gallbladder pseudolithiasis (PL) remains challenging. …”
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An integrated investigation of mitochondrial genes in COPD reveals the causal effect of NDUFS2 by regulating pulmonary macrophages by Xiaoli Zou, Qiqing Huang, Tutu Kang, Shaoran Shen, Chenxi Cao, Jianqing Wu

“…The 32 hub MitoDEGs identified from protein-protein interaction (PPI) networks demonstrated superior overall diagnostic efficacy to non-hub MitoDEGs. Random forest (RF) analysis, least absolute shrinkage and selection operator (LASSO) regression, and Mendelian Randomization (MR) analysis of hub MitoDEGs further nominated NDUFS2, CAT, and MRPL2 as causal MitoDEGs for COPD, whose predominate expressions in pulmonary macrophages were revealed by an independent single-cell transcriptomic dataset of COPD human lungs. …”
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Laser speckle contrast imaging with principal component and entropy analysis: a novel approach for depth-independent blood flow assessment by Yu. Surkov, P. Timoshina, I. Serebryakova, D. Stavtcev, I. Kozlov, G. Piavchenko, I. Meglinski, A. Konovalov, D. Telyshev, S. Kuznetcov, E. Genina, V. Tuchin

“…The proposed approach holds great potential for non-invasive biomedical imaging, offering improved diagnostic accuracy and contrast in vascular imaging. …”
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Antibiotic Resistance of Enteric Bacteria in HIV-Infected Patients at the Banka Ad-Lucem Hospital, West Region of Cameroon by Ornella J. T. Ngalani, Armelle T. Mbaveng, Wiliane J. T. Marbou, Roland Y. Ngai, Victor Kuete

“…Stool samples from one-hundred HIV-positive patients with enteric disorders and forty HIV negative patients with enteric disorders were examined for the presence of bacteria by different diagnostic techniques. CD4+ T-lymphocyte count and serum hs-CRP of HIV-positive and HIV-negative patients were examined, respectively, by flux cytometry and the ELISA solid-phase direct sandwich method. …”
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Association of The MCP-1 rs1024611 Polymorphism with Polycystic Ovary Syndrome in A Population of Indian Women: A Case-Control Study by Jijo Francis, Honey Sebastian, Saley Daniel, Leyon Varghese, Sareena Gilvaz, Ragitha Thenkattil Sankarankutty, Siji Susan George, Pulikkottil Raphael Varghese, Suresh Kumar Raveendran

“…In the Indian population, its prevalence varies from 3.7 to 22.5%depending on ethnicity and diagnostic criteria. Chronic inflammation plays a pivotal role in PCOS pathogenesis.The monocyte chemoattractant protein-1 (MCP-1) is an important chemotactic factor for inflammatory response ofmonocytes. …”
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