Direct imaging with multidimensional labelling and high‐content analysis allows quantitative categorization and characterizations of individual small extracellular vesicles and nan... by Simou Sun, Sarah J. Cox‐Vázquez, Nam‐Joon Cho, Guillermo C. Bazan, Jay T. Groves

“…Abstract Small extracellular vesicles and nanoparticles (sEVPs) are cell‐secreted entities with potential as diagnostic biomarkers and therapeutic vehicles. However, significant intrinsic sEVP heterogeneity impedes analysis and understanding of their composition and functions. …”
Get full text

X-Linked Autism Type 9 Caused by a Hemizygote Pathogenic Variant in the TMLHE Gene: Etiological Diagnosis in an Adult Male with Moderate Intellectual Disability by Verhoeven WM, Pfundt R, Engelke UF, Kluijtmans LA, Egger JI

“…To prevent regressive autistic episodes in young children, it is highly recommended to consider next-generation sequencing techniques as the first step in the differential diagnostic process of autism.Keywords: epsilon-trimethyllysine hydroxylase gene, TMLHE, levocarnitine, autism, intellectual disability, contextual neuropsychology, psychopathology…”
Get full text

Efficacy of transbronchial biopsy and frequency of pneumothorax in lung transplant recipients: single center experience by Ertan Sarıbaş, Ayse Nigar Halis, Sevinç Çıtak, Gonca Gecmen, Ahmet Murat Kazan, Musatafa Vayvada, Murat Ersin Cardak, Ahmet Erdal Taşçı

“…Despite advances in immunology and genetics, TBB remains the gold standard for detecting acute rejection (AR) following lung transplantation. Given its diagnostic value, we believe that the procedure should not be avoided due to the risks of complications.…”
Get full text

Clinical symptoms of acute appendicitis correlating to its intraoperative anatomical position by Chandan Singh, Aamina Hamdule, Amey Kasbekar, Shishir Kamble

“…Furthermore, it assessed the diagnostic accuracy of clinical examination and ultrasound in determining the appendix's position. …”
Get full text

Underestimated latent tuberculosis infection burden among school contacts in China: a cross-sectional study by Jin Yin, Mei Wang, Chengguo Wu, Yaling Shi, Ying Liu, Ya Yu, Qian Su, Zhengyu Zhang, Xueyong Huang, Xiaoshuang Zhang, Jun Fan, Bo Wu

“…TST, creation tuberculin skin test (C-TST), or Interferon-gamma release assays (IGRA) were conducted for immunological diagnostic methods. The LTBI detection gap among school contacts was assessed by comparing with the data implemented by community-level medical and health care institutions from 2021 to 2022. …”
Get full text

Individualized drug therapy and survival prediction in ICU patients with acute kidney injury: construction and validation of a nomogram by Rui Yang, Xiaozhe Su, Ziqi Liu, Shuai Shao, Yinhuai Wang, Hao Su, Haiqing He

“…The predictive model demonstrated diagnostic accuracy, with AUC values for 1-year, 3-year, and 5-year survival among AKI patients of 0.827, 0.799, and 0.777 in the training dataset, and 0.760, 0.743, and 0.740 in the internal validation dataset, respectively. …”
Get full text

The Validity Of 75gms OGTT For Detection Of GDM Keeping 100gms OGTT As Gold Standard by Shazia Mehreen, Muhammad Usman, Kashif Rauf, Saima Naz, Muhammad Abdul Rab Faisal Sultan, Muhammad Akram Randhawa

“…However, the overall diagnostic accuracy of OGTT-75 g was 82.93%. Conclusion: Results of this study showed that 75 gms OGTT is highly sensitive (83.02%) and specific (82.83%) for the detection/diagnosis of gestational DM. …”
Get full text

Outer Membrane Proteome Analysis of Indian Strain of Pasteurella multocida Serotype B:2 by MALDI-TOF/MS Analysis by A. Prasannavadhana, Santosh Kumar, Prasad Thomas, Laxmi Narayan Sarangi, Santosh Kumar Gupta, Adyasha Priyadarshini, Viswas Konasagara Nagaleekar, Vijendra Pal Singh

“…Further functional in vivo study of the proteins identified are required to explore the utility of these proteins in developing diagnostics and vaccine against HS.…”
Get full text

The White Matter Functional Abnormalities in Patients with Transient Ischemic Attack: A Reinforcement Learning Approach by Huibin Ma, Zhou Xie, Lina Huang, Yanyan Gao, Linlin Zhan, Su Hu, Jiaxi Zhang, Qingguo Ding

“…Furthermore, a reinforcement learning method was used to investigate whether altered WM function could be a diagnostic indicator of TIA. Methods. We enrolled 48 patients with TIA and 41 age- and sex-matched healthy controls (HCs). …”
Get full text

Adherence to Dihydroartemisinin-Piperaquine Treatment among Patients with Uncomplicated Malaria in Northern Ghana by Abraham Rexford Oduro, Samuel Chatio, Paula Beeri, Thomas Anyorigiya, Rita Baiden, Philip Adongo, Patricia Akweongo

“…A total of 405 patients were screened; 299 were positive by rapid diagnostic testing and 216 by microscopy. The average age was 12 years and females represented 54.0%. …”
Get full text

Comprehensive Analysis of <i>blaCTX-M1</i> Gene Expression Alongside <i>iutA</i>, <i>csgA</i>, and <i>kpsMII</i> Virulence Genes in Septicemic <i>Escherichia coli</i> Using Real-Ti... by Mohsen Karbalaei, Mojgan Esmailpour, Valentyn Oksenych, Majid Eslami

“…The key to treating these diseases is having sophisticated diagnostic tools and using antibiotics cautiously.…”
Get full text

Tumor volume changes after stereotactic, hypofractionated and conventional radiotherapy in paragangliomas of head and neck by Paweł J. Polanowski, Agnieszka R. Kotecka‐Blicharz, Andrzej Tukiendorf, Natalia J. Amrogowicz, Aleksandra M. Nasiek, Agnieszka Pietruszka, Katarzyna M. Polanowska, Krzysztof A. Składowski

“…The volumes of irradiated tumors were measured and compared based on diagnostic images performed before and after the treatment. …”
Get full text

Vertical Movement of Head, Withers, and Pelvis of High-Level Dressage Horses Trotting in Hand vs. Being Ridden by Hilary M. Clayton, Sarah Jane Hobbs, Marie Rhodin, Elin Hernlund, Mick Peterson, Rosalie Bos, Filipe Serra Bragança

Get full text

Factors Influencing Background Parenchymal Enhancement in Breast Contrast-Enhanced Mammography: A Retrospective Study by Xue J, Qu T, Li Z, Shi B, Yang G, Rong X, Li Y, Lin G, Ping Y

“…Additionally, to characterize the dynamic changes in BPE during CEM.Methods: This retrospective study included 103 women who underwent CEM at a single institution between September 2019 and November 2021 for screening or diagnostic purposes. Menopausal status and menstrual cycle phase were recorded for all patients. …”
Get full text

Cryptogenic Organizing Pneumonia with a Rare Radiographic Presentation of a Diffuse Micronodular Pattern Mimicking Miliary Lung Infiltration: A Case Report and Review of the Litera... by Jakrin Kewcharoen, Kittika Poonsombudlert, Sakda Sathirareuangchai, Wichit Sae-Ow, Hanh La, Narin Sriratanaviriyakul

“…He was then started on empiric antibiotics for community-acquired pneumonia and underwent a diagnostic bronchoscopy with alveolar lavage and transbronchial biopsies, which yielded negative cultures and unrevealing pathology. …”
Get full text

Operational Protocol for Prosthetically Guided Reconstruction of Edentulous Sites Using a Custom-Made Technique by Edoardo Brauner, Federico Laudoni, Lucia Terribile, Andrea Bellizzi, Giulia Amelina, Francesca De Angelis, Nicola Pranno, Stefano Di Carlo

“…Patients underwent meticulous preoperative planning, in which digital diagnostic wax-ups and RealGUIDE™ software for implant positioning were used. …”
Get full text

Advancing risk stratification in kidney transplantation: integrating HLA-derived T-cell epitope and B-cell epitope matching algorithms for enhanced predictive accuracy of HLA compa... by Matthias Niemann, Matthias Niemann, Benedict M. Matern, Benedict M. Matern, Gaurav Gupta, Bekir Tanriover, Fabian Halleck, Klemens Budde, Eric Spierings, Eric Spierings

Get full text

Risk Factors for Prolonged Length of Stay of Older Patients in an Academic Emergency Department: A Retrospective Cohort Study by Özcan Sir, Gijs Hesselink, Mara Van Den Bogaert, Reinier P. Akkermans, Yvonne Schoon

“…Risk factors for prolonged LOS of older patients at the ED were follows: higher number (more than one) of consultations (OR [odds ratio] 2.4, CI [confidence interval] 2.0-2.91), or diagnostic interventions (OR 1.5, CI 1.4-1.7); presenting complaints of a neurological (OR 2.2, CI 1.0-4.5) or internal medicine focus (OR 2.6, CI 1.4-4.6); patients with an altered consciousness (OR 3.3, CI 1.6-6.6); treatment by physicians of the departments of surgery (OR 3.4, CI 2.2-5.2), internal medicine (OR 2.6, CI 1.9-3.7), or pulmonology (OR 2.2, CI 1.4-3.6); and urgency category of ≥ U1. …”
Get full text

Automated diagnosis and classification of metacarpal and phalangeal fractures using a convolutional neural network: a retrospective data analysis study by Michael Axenhus, Anna Wallin, Jonas Havela, Sara Severin, Ablikim Karahan, Max Gordon, Martin Magnéli

“… Background and purpose: Hand fractures are commonly presented in emergency departments, yet diagnostic errors persist, leading to potential complications. …”
Get full text

Optimization of cultivation parameters for bovine respiratory syncytial virus strain Vologda/2019 by V. V. Kirpichenko, S. V. Kononova, I. N. Shumilova, A. A. Nesterov, M. V. Turkova, Ye. A. Bukhon, D. V. Romenskaya, A. V. Sprygin, B. L. Manin, O. P. Byadovskaya

“…In this regard, it is relevant to study the biological properties of the virus, optimize the methods of its cultivation and select the most technologically advanced methods of designing diagnostic and prevention tools for this disease. The aim of this work was to select sensitive cell systems and to optimize the cultivation parameters in selected cell cultures. …”
Get full text