Tunable control of Cas12 activity promotes universal and fast one-pot nucleic acid detection by Zhou-Hua Cheng, Xi-Yan Luo, Sheng-Song Yu, Di Min, Shu-Xia Zhang, Xiao-Fan Li, Jie-Jie Chen, Dong-Feng Liu, Han-Qing Yu

“…Abstract The CRISPR-based detection methods have been widely applied, yet they remain limited by the non-universal nature of one-pot diagnostic approaches. Here, we report a universal one-pot fluorescent method for the detection of epidemic pathogens, delivering results within 15-20 min. …”
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Serum connexin 26 as a potential marker of non-syndromic hearing loss by Hend M. Moness, Noha M. Abdullah, Doaa El Amrousy, Reham Gamal, Hatem A. Mohamed, Mohammed A. Gomaa, Shaimaa Moustafa Hafez, Zamzam Hassan Mohamed

“…Conclusion Serum connexin 26 could be used as a good diagnostic marker to detect NSHL in children. It could be used as a potential marker for NSHL in newborns as it is more rapid and easily available than genetic study, especially in developing countries.…”
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Spectral Domain Optical Coherence Tomography Assessment of Macular and Optic Nerve Alterations in Patients with Glaucoma and Correlation with Visual Field Index by Alessio Martucci, Nicola Toschi, Massimo Cesareo, Clarissa Giannini, Giulio Pocobelli, Francesco Garaci, Raffaele Mancino, Carlo Nucci

“…To evaluate the sectorial thickness of single retinal layers and optic nerve using spectral domain optic coherence tomography (SD-OCT) and highlight the parameters with the best diagnostic accuracy in distinguishing between normal and glaucoma subjects at different stages of the disease. …”
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Plasma microRNA signatures predict prognosis in canine osteosarcoma patients. by Latasha Ludwig, Michael Edson, Heather Treleaven, Alicia M Viloria-Petit, Anthony J Mutsaers, Roger Moorehead, Robert A Foster, Ayesha Ali, R Darren Wood, Geoffrey A Wood

“…Previous studies have demonstrated the diagnostic and prognostic potential of miRNAs in canine OSA. …”
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Hydroxychloroquine-induced Sweet’s Syndrome: A Case Report and Literature Review by Gustavo Almeida-Silva, Joana Antunes, Inês Tribolet de Abreu, Filipe Monteiro, Pedro Vasconcelos, Luís Soares-Almeida, Paulo Filipe

“…Further studies are necessary to shed light on the pathophysiology behind this entity, to further facilitate diagnostic workup and treatment strategies. …”
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Risk factors for the mortality of hemodialysis patients with COVID-19 in northern Hunan province, China by Zhangxiu He, Zhong Peng, Ning Gao, Shuzhu Zhong, Fengyi Yu, Zixu Tang, Zihao Liao, Song Zhao, Gloria Umwiza, Ming Chen, Wei Long

“…The receiver operating characteristic (ROC) curve was used to determine the diagnostic value of risk factors in hemodialysis COVID-19 patients. …”
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Immunoglobulin G4-related disease with pleural involvement in an 80-year-old female patient: A case report and literature review by Liying Zhang, Li Mo

“…This study presents a case of pleural IgG4-RD and reviews the literature to elucidate the patient population, manifestations, and diagnostic and treatment characteristics of pleural IgG4-RD. …”
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Characterization of Helicobacter Pylori Infection in Patients with Gastric Ulcer by Marcos Félix Osorio Pagola, Magalys Blanca Olivert Cruz, Juan Luís de Pasos Carrazana, Alfredo Basilio Quiñones Ceballos, Mabel Vega Galindo, Anagalys Ortega Alvelay

“…Endoscopy and mucous gastric biopsy were performed for the histological and diagnostic study of the infection due to Helicobacter Pylori by means of the hematoxiline-eosine and giemsa stain respectively. …”
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Effect of Aquatic Treadmill Training on Patients with Hemiplegia after Stroke by WANG Yanan, ZHANG Tong, LIU Huilin, DU Xuejing, ZHU Xiaomin, LIU Yuanmin

“…Before and after treatment, a full digital handheld color ultrasound diagnostic instrument was used to measure the muscle thickness of obliquus externus abdominis (EO）, internal abdominal oblique (IO), transverse abdominal (TrA), rectus femoris (RF), tibialis anterior (TA) and medial gastrocnemius (MG). …”
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Metal‐based nanomaterials and nanocomposites as promising frontier in cancer chemotherapy by Sunil Kumar, Monu Kumar Shukla, Abhishek Kumar Sharma, Gururaj K. Jayaprakash, Rajiv K. Tonk, Dinesh K. Chellappan, Sachin Kumar Singh, Kamal Dua, Faheem Ahmed, Sanjib Bhattacharyya, Deepak Kumar

“…Nanomaterials (NMs) have unique properties that make them useful for various diagnostic and therapeutic purposes in cancer research. …”
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Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with ApcMin/+ Mutation by Michele Barone, Maria Principia Scavo, Raffaele Licinio, Michele Piombino, Nicola De Tullio, Rosanna Mallamaci, Alfredo Di Leo

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CBCT analysis of the incidence of maxillary lateral incisor dens invaginatus and its impact on periodontal supporting tissues by Yanhua Wang, Sha Su, Xing Chen, Xueting Jia

“…The reported incidence varies greatly due to diagnostic techniques, classification criteria and race. …”
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No Correlation Exists between Disease Activity and the Expression of Killer-Cell Immunoglobulin-Like Receptors in Patients with Rheumatoid Arthritis by Toshiaki Kogure, Takeshi Tatsumi, Atsushi Niizawa, Hiroshi Fujinaga, Tomoyuki Ito, Yutaka Shimada, Katsutoshi Terasawa

“…In the cross-sectional study, 15 patients (9 females and 6 males) who fulfilled the diagnostic criteria for RA were assessed. In the longitudinal study, patients who were followed-up for 3 months were assessed. …”
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Bilateral Double Ureters with Bladder Neck Diverticulum in a Nigerian Woman Masquerading as an Obstetric Fistula by Imran O. Morhason-Bello, Sikiru A. Adebayo, Rukiyat A. Abdusalam, Oluwasomidoyin O. Bello, Kehinde H. Odubamowo, Olatunji O. Lawal, E. Oluwabunmi Olapade-Olaopa, Oladosu A. Ojengbede

“…This is to showcase some diagnostic dilemma that could arise with obstetric fistula, which is generally diagnosed by clinical assessment.…”
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A 2-Year, Phase IV, Multicentre, Observational Study of Ranibizumab 0.5 mg in Patients with Neovascular Age-Related Macular Degeneration in Routine Clinical Practice: The EPICOHORT... by Sergio Pagliarini, Stephen Beatty, Blandina Lipkova, Eduardo Perez-Salvador Garcia, Stefaan Reynders, Margarita Gekkieva, Abdelkader Si Bouazza, Stefan Pilz

“…Being observational in nature, the study did not impose diagnostic/therapeutic interventions/visit schedule. …”
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Evaluating Normalization Methods for Robust Spectral Performance Assessments of Hyperspectral Imaging Cameras by Siavash Mazdeyasna, Mohammed Shahriar Arefin, Andrew Fales, Silas J. Leavesley, T. Joshua Pfefer, Quanzeng Wang

“…Hyperspectral imaging (HSI) technology, which offers both spatial and spectral information, holds significant potential for enhancing diagnostic performance during endoscopy and other medical procedures. …”
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The performance of a lateral flow SARS-CoV-2 antibody assay and semi-autonomous SARS-CoV-2 antisense and sense RNA fluorescence in situ hybridization assay in a prospective cohort... by Inge D Wijnberg, Anton J Soons, Johan G Reimerink, Marit Wiersma, Marie Christine J Plat, Tom van Gool, Gijsbert J Jansen, Cornelis Stijnis, Jack G Koning, Adam Meijer

“…At the beginning of the COVID-19 pandemic, diagnostic testing was not accessible for mildly ill or asymptomatic individuals. …”
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The role of repeat fine needle aspiration in managing indeterminate thyroid nodules by Laura Allen, Ayham Al Afif, Matthew H. Rigby, Martin J. Bullock, Jonathan Trites, S. Mark Taylor, Robert D. Hart

“…It is unclear how often rFNA provides additional diagnostic information. We sought to investigate its utility at our institution. …”
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Could serum Raftlin and GPER-1levels be new biomarkers for early detection of non-small cell lung cancer? by Aykut Eliçora, Berrak Güven, Hüseyin Engin, Gokcen Tugba Çevik, Hüseyin Fatih Sezer

“…Therefore, it was thought that GPER-1 could be evaluated as a diagnostic marker in lung cancer. However, we think that more definitive results can be obtained by determining the tissue and expression level of GPER in lung cancer with further studies.…”
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Downregulation of RIPK4 Expression Inhibits Epithelial-Mesenchymal Transition in Ovarian Cancer through IL-6 by Huan Yi, Yan-zhao Su, Rong Lin, Xiang-qin Zheng, Diling Pan, Dan-mei Lin, Xiang Gao, Rong Zhang

“…This finding may provide a novel diagnostic and therapeutic target for improving the poor prognoses of OC patients.…”
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