Role of silent mutations in KRAS-mutant tumors by Jun Lu, Chao Zhou, Feng Pan, Hongyu Liu, Haohua Jiang, Hua Zhong, Baohui Han, Xiangxiang Pan

“…Moreover, investigations into the clinical implications of silent mutations in KRAS-mutant tumors suggest potential diagnostic and therapeutic strategies. Despite being in early stages, research on KRAS silent mutations holds promise for uncovering novel insights that could inform personalized cancer treatments. …”
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Descriptive Analysis Regarding Optic Canal Variations: A Study In South Punjab Region Of Pakistan by Ponum Mirani, Ammara Rasheed, Gul Afshan, Nida Rasheed

“…These results hold practical implications for clinicians, informing diagnostic imaging, surgical planning, and interventions involving the optic canal. …”
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Assessment of Brushing Techniques in School Children and Its Association with Dental Caries, Omdurman, 2019 by Rugaia Eltayeb Hag Maki Ibrahim, Maha O. Helaly, Ehab Mohamed Abdelhlim Ahmed

“…The diagnosis was done based on the World Health Organization diagnostic criteria 2013. The data were analyzed through descriptive statistics and comparison between values using the chi-square test with a P value <0.05. …”
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ReIU: an efficient preliminary framework for Alzheimer patients based on multi-model data by Hao Jiang, Hao Jiang, Yishan Qian, Yishan Qian, Yishan Qian, Liqiang Zhang, Liqiang Zhang, Tao Jiang, Tao Jiang, Yonghang Tai, Yonghang Tai

“…The rising incidence of Alzheimer’s disease (AD) poses significant challenges to traditional diagnostic methods, which primarily rely on neuropsychological assessments and brain MRIs. …”
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Retrospective analysis of enzootic bovine leucosis spread in Republic of Dagestan considering natural and climatic conditions by A. R. Mustafayev, M. O. Baratov

“…High BLV infection levels were detected in 1988 (32.2%), 1989 (21.3%), 1991 (23.3%), 1993 (23.0%), 2005 (24.2%), 2010 (23.0%), and the lowest ones were reported in the recent years: 2020 – 1.0%, 2021 – 1.0%, 2022 – 0.5%. In2022, diagnostic testing of 875,312 serum samples was carried out, which included 476,493 sera collected from bovines in high-altitude and mountainous areas of Dagestan. …”
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Intra- and interspecific variability of <i>Mentha arvensis</i> L. and <i>M. Canadensis</i> L. by M. V. Semenova, O. L. Enina, O. V. Shelepova

“…Eight geographically dispersed populations of Mentha in different regions (European Russia, Khakassia and Far East, Western Ukraine, and Indochina) were studied. Diagnostic morphological characters and compositions of essential oil components were examined, and DNA was analyzed with ISSR markers. …”
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Diagnosis of Fanconi Anemia: Mutation Analysis by Multiplex Ligation-Dependent Probe Amplification and PCR-Based Sanger Sequencing by Johan J. P. Gille, Karijn Floor, Lianne Kerkhoven, Najim Ameziane, Hans Joenje, Johan P. de Winter

“…We describe a strategy and optimized conditions for the screening of FANCA, FANCB, FANCC, FANCE, FANCF, and FANCG and present the results obtained in a cohort of 54 patients referred to our diagnostic service since 2008. In addition, the follow up with respect to genetic counseling and carrier screening in the families is discussed.…”
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Performance of indirect adherence measures for daily oral pre-exposure prophylaxis for HIV among adolescent men who have sex with men and transgender women in Brazil. by Diana Zeballos, Laio Magno, Fabiane Soares, Jony Arrais Pinto Junior, Leila Amorim, Dirceu Greco, Alexandre Grangeiro, Inês Dourado, PrEP15-19 study group

“…<h4>Methods</h4>PrEP15-19 is a prospective, multicenter, PrEP demonstration cohort study that includes AMSM and ATGW aged 15-19 in three Brazilian cities. A diagnostic accuracy study was conducted using tenofovir-diphosphate (TFV-DP) concentrations in dried blood spots as the reference standard, along with three index tests: medication possession ratio (MPR), pill count, and self-report. …”
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The value of lung ultrasound score combined with echocardiography in assessing right heart function in patients undergoing maintenance hemodialysis and experiencing pulmonary hyper... by Ying Xia, Xin Liu

“…A receiver operating characteristic (ROC) curve and calculate the area under the curve(AUC) to compare the diagnostic efficacy of various parameters. Results Patients undergoing MHD exhibited varying degrees of reduced left ventricular (LV) and RV systolic function. …”
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Dengue Infection and Its Relationship with Evans Syndrome: A Pediatric Case by Ivan Jose Ardila Gomez, Pilar Pérez López, Mónika Rocío Hernández Carreño, Juan Camilo Barrios Torres

“…Here, we present the case of an unusual hematological and immunological complication of a patient who developed Evans syndrome during severe dengue, taking into account the concomitantly limited literature available for these two diseases, the need for a broader diagnostic approach, multidisciplinary intervention, and a more complex therapeutic approach.…”
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Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department by John E. Schneider, Jonathan Romanowsky, Philipp Schuetz, Ivana Stojanovic, Henry K. Cheng, Oliver Liesenfeld, Ljubomir Buturovic, Timothy E. Sweeney

“…While early detection and initiation of treatment reduces mortality, inappropriate treatment leads to adverse events and the development of antimicrobial resistance. Current diagnostic and prognostic solutions, including procalcitonin, lack required accuracy. …”
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Solitary fibular metastasis from lung adenocarcinoma with gene mutation: a case report by Jiechen Chen, Ahmad Alkhatatbeh, Yinbing Lin, Xiaolin Lu, Bin Chen, Hongjiang Chen, Xiaohui Lu, Hansheng Wu, Jun Hu

“…This case highlights the diagnostic challenge posed by atypical presentations of metastasis and underscores the importance of comprehensive evaluation, adherence to treatment guidelines, and a multidisciplinary approach in managing oncological patients. …”
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Correlation of Clinical, Endoscopic, and Pathological Findings among Suspected Peptic Ulcer Disease Patients in Abuja, Nigeria by Onyedika Godfrey Okoye, Oluwole Olayemi Olaomi, Alexander M.E. Nwofor, Paul Jibrin, Cephas Shallangwa Batta, Abubakar Gagarawa Yaú, Olawale A. Badejo

“…To determine the correlation between the endoscopic and pathological findings among suspected PUD patients who have been referred for diagnostic upper gastrointestinal endoscopy in National Hospital Abuja. …”
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Head and Neck Paragangliomas: 16-year Single-center Experience and Mini Review on Diagnosis, Treatment, and Follow-up by Gokce AYDEMIR, Fazil Necdet ARDIC, Cuneyt Orhan KARA, Ferda BIR

“…The additional goal is to contribute to the existing knowledge on head and neck paraganglioma, with a particular emphasis on refining diagnostic algorithms, treatment selection, and follow-up procedures. …”
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The Effectiveness of Dipstick for the Detection of Urinary Tract Infection by Isaac Dadzie, Elvis Quansah, Mavis Puopelle Dakorah, Victoria Abiade, Ebenezer Takyi-Amuah, Richmond Adusei

“…The balance between the choices of UTI diagnostic tools in most primary care settings has been settled for by the more rapid, less labour-intensive dipstick. …”
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Resnet-1DCNN-REA bearing fault diagnosis method based on multi-source and multi-modal information fusion by Xu Chen, Wenbing Chang, Yongxiang Li, Zhao He, Xiang Ma, Shenghan Zhou

“…Finally, the tree-structured parzen estimator (TPE) algorithm was utilized to realize the integration of two models in order to improve the diagnostic effect of a single model and obtain the final bearing fault diagnosis results. …”
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Comprehensive analysis pinpoints CCNA2 as a prognostic and immunological biomarker in non-small cell lung cancer by Liming Zhang, Shaoqiang Wang, Lina Wang

“…The area under the curve (AUC) of CCNA2 indicating high diagnostic accuracy. Immune infiltration and single-cell sequencing revealed that CCNA2 expression was significantly associated with immune cell infiltration, particularly in Tprolif cells. …”
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A comparison of CXR-CAD software to radiologists in identifying COVID-19 in individuals evaluated for Sars CoV-2 infection in Malawi and Zambia. by Sam Linsen, Aurélie Kamoun, Andrews Gunda, Tamara Mwenifumbo, Chancy Chavula, Lindiwe Nchimunya, Yucheng Tsai, Namwaka Mulenga, Godfrey Kadewele, Eunice Nahache Kajombo, Veronica Sunkutu, Jane Shawa, Rigveda Kadam, Matthew Arentz

“…These findings suggest that while current AI-based diagnostics like CXR-CAD show promise, their effectiveness varies significantly. …”
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Explainable machine learning framework for cataracts recognition using visual features by Xiao Wu, Lingxi Hu, Zunjie Xiao, Xiaoqing Zhang, Risa Higashita, Jiang Liu

“…Experiments on a clinical AS-OCT-NC dataset demonstrate that the proposed framework not only achieves competitive performance through comparisons with DNNs, but also has a good explanation ability, meeting the requirements of clinical diagnostic practice.…”
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Pathophysiology and Treatment of Psoriasis: From Clinical Practice to Basic Research by Yujie Gao, Tianqi Xu, Yu Wang, Yanjinhui Hu, Shaoping Yin, Zhiguo Qin, Hua Yu

“…Current psoriasis diagnoses are primarily clinician-dependent, with instrumental diagnostics serving as adjuncts. Ongoing research is progressively deciphering its molecular underpinnings; the future of psoriasis diagnostics may involve genetic and immunological profiling to pinpoint biomarkers, enabling more accurate and timely interventions. …”
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