Application of lacrimal gland ultrasonography in the evaluation of chronic ocular graft-versus-host-disease by Mingxia Zhong, Siyuan Liu, Jinghan Luo, Qin Zhang, Zhou Yang, Shanshan Zhang

“…Patients were categorized into groups according to the International Chronic oGVHD (ICCGVHD) consensus group diagnostic criteria or the 2005 National Institutes of Health (NIH) classification criteria for Chronic GVHD. …”
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Evidence Gaps and Lessons in the Early Detection of Atrial Fibrillation: A Prospective Study in a Primary Care Setting (PREFATE Study) by Josep L. Clua-Espuny, Alba Hernández-Pinilla, Delicia Gentille-Lorente, Eulàlia Muria-Subirats, Teresa Forcadell-Arenas, Cinta de Diego-Cabanes, Domingo Ribas-Seguí, Anna Diaz-Vilarasau, Cristina Molins-Rojas, Meritxell Palleja-Millan, Eva M. Satué-Gracia, Francisco Martín-Luján

“…<b>Conclusions:</b> The study underscores the feasibility and utility of AF screening in primary care but identifies critical gaps in diagnostic criteria, anticoagulation thresholds, and guideline recommendations.…”
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The role of mNGS in the diagnosis of talaromycosis and case series by Jing Zhao, Hui-Ting Su, Dong Zhang, Xue-Tong Li, Min-Ya Lu, Juan Du, Jia-Yu Guo, Yi Gao, Xin-Fei Chen, Dong-Hua Wen, Shi-Yu Jia, Yao Wang, Qi-Wen Yang

“…Conclusions Traditional diagnostic methods are limited by factors such as the long time and low sensitivity of fungal culture, the effect of prior antibiotic treatment, the invasiveness and complexities of tissue biopsies, and so on. …”
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Age-related changes in brain signal variability in autism spectrum disorder by Priyanka Sigar, Nicholas Kathrein, Elijah Gragas, Lauren Kupis, Lucina Q. Uddin, Jason S. Nomi

“…RRBs were assessed using the Autism Diagnostic Interview-Revised (ADI-RRB) scale. BSV was quantified using the root-mean-square successive difference (rMSSD) of the resting-state fMRI time series. …”
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Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo by Jean Ikanga, Jean Ikanga, Saranya Sundaram Patel, Saranya Sundaram Patel, Megan Schwinne, Caterina Obenauf, Caterina Obenauf, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Lelo Mananga, Charlotte E. Teunissen, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Emile Omba, Alvaro Alonso, Alden L. Gross

“…ObjectiveThe 2024 Alzheimer’s Association (AA) research diagnostic criteria for Alzheimer’s Disease (AD) considers fluid biomarkers, including promising blood-based biomarkers for detecting AD. …”
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Circulating Isthmin-1 Levels and Their Relationship with Diabetes and Metabolic Diseases in Kuwaiti Adults by Eman Alshawaf, Sulaiman K. Marafie, Mohamed Abu-Farha, Ahmed N. Albatineh, Tahani Alramah, Aldana Albuhairi, Yafa Al Qassar, Reem Zinoun, Rawan Shalabi, Sarah Behbehani, Dalal Mohammed, Fahad Alajmi, Mohammed A. Abdalla, Ebaa Al-Ozairi, Mohammad Shehab, Muhammad Abdul-Ghani, Fahd Al-Mulla, Jehad Abubaker

“…Furthermore, our ROC results indicate that circulatory Ism1 levels possess significant diagnostic capability for identifying individuals with obesity-related metabolic imbalances with an area under the curve of 0.764 (95% CI = 0.718, 0.811). …”
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Diagnosis and treatment of disorders of intracranial pressure: consensus statement of the Spanish Society of Neurology’s Headache Study Group by J. García-Ull, N. González-García, M. Torres-Ferrús, D. García-Azorín, I.F.J. Molina-Martínez, I. Beltrán-Blasco, S. Santos-Lasaosa, G. Latorre, A.B. Gago-Veiga, J.M. Láinez, J. Porta-Etessam, C. Nieves-Castellanos, A. Mínguez-Olaondo, A. López-Bravo, S. Quintas, N. Morollón, S. Díaz-Insa, R. Belvís, P. Irimia

“…Therefore, the Spanish Society of Neurology's Headache Study Group (GECSEN) deemed it necessary to prepare this consensus statement, including diagnostic and therapeutic algorithms to facilitate and improve the management of these disorders in clinical practice.This document was created by a committee of experts belonging to GECSEN, and is based on a systematic review of the literature, incorporating the experience of the participants, and establishes practical recommendations with levels of evidence and grades of recommendation. …”
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Evaluation of Bone Mineral Metabolism in Pre-Dialysis Chronic Kidney Disease: Quantitative Computed Tomography vs. Dual-Energy Absorptiometry and Correlation with Bone Turnover Mar... by Aydan Mutis Alan, Zehra Sezer, Ahmet Oz, Cebrail Karaca, Mevlüt Tamer Dinçer, Ahmet Murt, Fatma Beyza Sag, Selma Alagoz, Serdar Sahin, Mustafa Sait Gonen, Elif Güzel, Sinan Trabulus, Nurhan Seyahi

“…The participants’ bone and mineral status was evaluated using both QCT and DXA methods. Diagnostic measurements of the lumbar spine and femoral neck, obtained using DXA and QCT, were compared. …”
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TRACE Model: Predicting Treatment Response to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma by Wang W, Zhang Q, Cui Y, Zhang S, Li B, Xia T, Song Y, Zhou S, Ye F, Xiao W, Cao K, Chi Y, Qu J, Zhou G, Chen Z, Zhang T, Chen X, Ju S, Wang YC

“…Weilang Wang,1,&ast; Qi Zhang,2,&ast; Ying Cui,1,&ast; Shuhang Zhang,1 Binrong Li,1 Tianyi Xia,1 Yang Song,3 Shuwei Zhou,1 Feng Ye,4 Wenbo Xiao,5 Kun Cao,6 Yuan Chi,7 Jinrong Qu,8 Guofeng Zhou,9,10 Zhao Chen,11 Teng Zhang,12 Xunjun Chen,13 Shenghong Ju,1 Yuan-Cheng Wang1 1Department of Radiology, Zhongda Hospital, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, School of Medicine, Southeast University, Nanjing, 210009, People’s Republic of China; 2Center of Interventional Radiology and Vascular Surgery, Department of Radiology, Zhongda Hospital, Medical School, Southeast University, Nanjing, People’s Republic of China; 3MR Scientific Marketing, Siemens Healthineers Ltd, Shanghai, People’s Republic of China; 4Department of Diagnostic Radiology, National Cancer Center/National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People’s Republic of China; 5Department of Radiology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, People’s Republic of China; 6Department of Radiology, Peking University Cancer Hospital and Institute, Beijing, People’s Republic of China; 7Department of Radiology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China; 8Department of Radiology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou, Henan, People’s Republic of China; 9Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai, People’s Republic of China; 10Shanghai Institute of Medical Imaging, Shanghai, People’s Republic of China; 11Department of Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China; 12Institute for Artificial Intelligence in Medicine, School of Artificial Intelligence, Nanjing University of Information Science and Technology, Nanjing, People’s Republic of China; 13Department of Radiology, The People’s Hospital of Xuyi County, Huaian, Jiangsu, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yuan-Cheng Wang, Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology, Department of Radiology, Zhongda Hospital, School of Medicine, Southeast University, 87 Ding Jia Qiao Road, Nanjing, Jiangsu, 210009, People’s Republic of China, Tel +086 25 83272121, Fax +086 25 83311083, Email yuancheng_wang@seu.edu.cnPurpose: To develop and validate a predictive model for predicting six-month outcome by integrating pretreatment MRI features and one-month treatment response after TACE.Methods: A total of 108 patients with 160 hCCs from a single-arm, multicenter clinical trial (NCT03113955) were analyzed and served as the training cohort. …”
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Survey on the Status and Training Demands of Capabilities for Diagnosing and Treating Common Diseases of Primary Care General Practitioners in Hunan Province by LI Lingqi, GAO Yinyan, ZHANG Yuqin, SUN Dingkui, WU Xinyin, ZHANG Weiru

“…Additionally, 77.2% (260/337) of participants lacked sufficient knowledge of clinical practice guidelines; 90.8% (306/337) of participants rarely consulted guidelines when facing decision-making difficulties, mainly because they felt guidelines could not address complex cases[50.0% (153/306) ], were unclear on how to search for guidelines[43.1% (132/306) ]and the resources available for retrieving guidelines[34.3% (105 /306) ]; participants mainly obtain the guidelines through the WeChat official account[72.5% (237/327) ] and databases such as the China National Knowledge Infrastructure [50.2% (164/327) ]. 97.0% (327/337) of participants expressed a demand for training to improve their capabilities, suggesting that training should be tailored to the specific needs of primary care institutions[60.8% (205/337) ]; the preferred approaches are advanced training in higher-level hospitals[71.3% (233/327) ]and primary care institutions with high diagnostic and treatment capabilities[56.3% (184/327) ]; the preferred training programs are on standardized treatment of common diseases[78.0% (263/337) ]and multiple coexisting diseases[69.4% (234/337) ]. …”
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MicroRNAs Expression Profile in MN1-Altered Astroblastoma by Francesca Gianno, Evelina Miele, Claudia Sabato, Elisabetta Ferretti, Simone Minasi, Francesca Romana Buttarelli, Debora Salerno, Natalia Pediconi, Giuseppe Rubens Pascucci, Francesca Guerrieri, Andrea Ciolfi, Simone Pizzi, Maura Massimino, Veronica Biassoni, Elisabetta Schiavello, Marco Gessi, Sofia Asioli, Angela Mastronuzzi, Antonio d’Amati, Giuseppina Catanzaro, Elisabetta Viscardi, David Capper, Felice Giangaspero, Manila Antonelli

“…Background/Objectives: Astroblastoma is a rare glial neoplasm more frequent in young female patients, with unclear clinical behaviors and outcomes. The diagnostic molecular alteration is a rearrangement of the Meningioma 1 (<i>MN1</i>) gene. …”
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A meta-analysis of randomized controlled trials: evaluating the efficacy of isokinetic muscle strengthening training in improving knee osteoarthritis outcomes by Wanqin Guo, Jingyang Gao, Dawazhuoma, Xiuling Mi, Ciwang, Bianba

“…The studies included were randomized controlled trials (RCTs) with participants from the plains who met the diagnostic criteria for KOA as outlined in the 2019 edition, with no restrictions on gender, age, or disease course, and no patients with advanced disease; studies where in the control group was either a non-intervention group or a group receiving treatment, other than IMST, and the experimental group received IMST alone or in addition to the treatment administered to the control group; and studies with at least two of the following outcome indicators: (i) knee flexors (Flex)/extensors (Ext) peak torque (PT), (ii) knee Flex/Ext total work (TW), (iii) knee Flex/Ext max rep total work (MRTW), (iv) knee Flex/Ext average power (AP), (v) visual analogue scale (VAS) for pain, (vi) Lequesne index (LI), (vii) Western Ontario and McMaster University Osteoarthritis Index (WOMAC), (viii) Lysholm Knee Scoring Scale (LKSS), (ix) range of motion (ROM) of the knee joint, and (x) 6-min walk test. …”
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Exploring the allometry between ear saturated water accumulation and dry mass for diagnosing winter wheat water status during the reproductive growth by Tingxuan Zhuang, Ben Zhao, Syed Tahir Ata-Ul-Karim, Gilles Lemaire, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…The study focused on developing and validating a model to quantify the water status of winter wheat during reproductive growth phase by using critical ear saturated water accumulation (SWAE) curves and water diagnostic index (WDI) based on ear, and to analyze the effect of water-nitrogen interaction on it. …”
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THE ORGANIZATION WORKS TO IMPROVE THE CLINICAL AND ECONOMIC OUTCOMES OF CARE FOR PROSTATE CANCER by O. I. Apolikhin, A. V. Sivkov, I. V. Chernishov, M. I. Katibov, O. V. Zolotukhin, I. A. Shaderkin, S. A. Leonov, D. A. Vojtko, M. Y. Prosyannikov

“…Then the patient is directed to the second stage of inter-regional urology center (ITC), whose task in the diagnostic phase is to verify the diagnosis.    In case of confirmation of the diagnosis by an urologist of ITC there was created the interactive consultation on the basis of remote Advisory portal Nethealth.ru together with leading research Institute of urology and regional urology center they identified the clinical significance of the disease and subsequent treatment strategy. …”
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Clinical Recommendations of Russian Gastroenterological Association and RENDO Endoscopic Society on Diagnosis and Treatment of Gastritis and Duodenitis by V. T. Ivashkin, I. V. Maev, T. L. Lapina, E. D. Fedorov, A. A. Sheptulin, A. S. Trukhmanov, A. V. Kononov, R. A. Abdulkhakov, O. P. Alexeeva, S. A. Alekseenko, D. N. Andreev, E. K. Baranskaya, N. N. Dekhnich, I. L. Klyaritskaya, R. S. Kozlov, E. A. Kogan, M. P. Korolev, N. V. Korochanskaya, S. A. Kurilovich, M. A. Livsan, M. F. Osipenko, P. V. Pavlov, S. S. Pirogov, A. S. Sarsenbaeva, V. I. Simanenkov, A. S. Tertychny, A. V. Tkachev, Yu. P. Uspensky, I. B. Khlynov, V. V. Tsukanov

“…The recommendations condense current knowledge on the aetiology and pathogenesis of gastritis and duodenitis, as well as laboratory and instrumental diagnostic techniques, main approaches to aetiological H. pylori eradication and treatment of dyspeptic states.…”
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QuickStroop for screening for minimal hepatic encephalopathy in patients with cirrhosis by Christian Labenz, Simon J. Gairing, Leonard Kaps, Alena F. Ehrenbauer, Eva M. Schleicher, Sophie Mengel, Julius F.M. Egge, Maria M. Gabriel, Peter R. Galle, Heiner Wedemeyer, Alexander Zipprich, Cristina Ripoll, Robin Greinert, Benjamin Maasoumy

“…In this study, we validated QuickStroop for patients in Germany with cirrhosis and demonstrate a good diagnostic accuracy for detecting MHE, especially in patients below 60 years of age. …”
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Evaluating the controlled reopening of nightlife during the COVID-19 pandemic: a matched cohort study in Sitges, Spain, in May 2021 (Reobrim Sitges) by Mercè Marzo-Castillejo, Joan Colom, Betlem Salvador-González, Josep Basora, Oriol Cunillera Puértolas, Sara Contreras-Martos, Darío López Gallegos, Mateo Acedo Anta, Jesús Almeda Ortega

“…To attend the event, participants were required to be older than 17 years, with a negative rapid antigen diagnostic test (Ag-RDT) on the same afternoon, without a positive reverse-transcription PCR (RT-PCR) or Ag-RDT and/or symptoms associated with COVID-19 in the previous 7 days, to not having knowingly been in close contact with someone infected in the previous 10 days and to not have knowingly had close contact with someone with a suspicion of COVID-19 in the previous 48 hours. …”
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Viral Hepatitis B and Its Implications for Public Health in DR Congo: A Systematic Review by Marcellin Mengouo Nimpa, Hermès Karemere, Christian Ngandu, Franck-Fortune Mboussou, M. Carolina Danovaro-Holliday, Dalau Nkamba, André Bita Fouda, Bienvenu Nguejio, Sifa Kakozi, Aimé Mwana-Wabene Cikomola, Jean-Crispin Mukendi, Dieudonné Mwamba, Moise Désiré Yapi, Richard Bahizire Riziki, Cedric Mwanga, John Otomba, Jean Baptiste Nikiema, Boureima Hama Sambo, Daniel Katuashi Ishoso

“…The review essentially analyzed the viral hepatitis B (HBV) vaccination status of study subjects, diagnostic means, HBV genotypes in DR Congo, seroprevalence of HBV infection, subjects’ level of knowledge and perceptions of HBV, co-infection/comorbidity with HBV infection, factors associated with HBV infection and public health issues raised by HBV infection. …”
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Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics by Ivan Rankovic, Ivana Babic, Jelena Martinov Nestorov, Jelena Bogdanovic, Maja Stojanovic, Jovanka Trifunovic, Nikola Panic, Mihailo Bezmarevic, Jelena Jevtovic, Dusan Micic, Vladimir Dedovic, Nemanja Djuricic, Filip Pilipovic, Elena Curakova Ristovska, Tijana Glisic, Sanja Kostic, Nemanja Stojkovic, Nata Joksimovic, Mileva Bascarevic, Aleksandra Bozovic, Lewis Elvin, Ajibola Onifade, Keith Siau, Elizaveta Koriakovskaia, Vladimir Milivojevic

“…Cirrhotic cardiomyopathy (CCM) is a diagnostic entity defined as cardiac dysfunction (diastolic and/or systolic) in patients with liver cirrhosis, in the absence of overt cardiac disorder. …”
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Prediction of pathological complete response after neoadjuvant chemotherapy for HER2-negative breast cancer patients with routine immunohistochemical markers by Lothar Häberle, Ramona Erber, Paul Gass, Alexander Hein, Melitta Niklos, Bernhard Volz, Carolin C. Hack, Rüdiger Schulz-Wendtland, Hanna Huebner, Chloë Goossens, Matthias Christgen, Thilo Dörk, Tjoung-Won Park-Simon, Andreas Schneeweiss, Michael Untch, Valentina Nekljudova, Sibylle Loibl, Arndt Hartmann, Matthias W. Beckmann, Peter A. Fasching

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