Traitement d’un lymphome agressif chez un babouin naturellement infecté par STLV-1 by Jocelyn Turpin, Sandrine Alais, Ambroise Marçais, Julie Bruneau, Anat Melamed, Nicolas Gadot, Olivier Hermine, Charles Bangham, Romain Lacoste, Renaud Mahieux

“…Ces symptômes étaient donc évocateurs d’une maladie hématologique provoquée par l’infection à STLV-1. Ce diagnostic fut confirmé par la présence d’une lymphoprolifération massive dans la biopsie d’un ganglion inguinal et par la présence de lymphocytes présentant un noyau typique en "trèfle", caractéristique des cellules ATL, dans les frottis sanguins. …”
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Durable responders in advanced NSCLC with elevated TMB and treated with 1L immune checkpoint inhibitor: a real-world outcomes analysis by David P Carbone, David Spigel, Jeffrey S Ross, Karthikeyan Murugesan, Gerald Li, Richard S P Huang, Ryon P Graf, Geoffrey R Oxnard, Alexa Schrock, Liangliang Zhang, Khaled Tolba, Jacob Sands

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Blastic plasmacytoid dendritic cell neoplasm: a Swiss case series of a very rare disease and a structured review of the literature by Ramona Meier-Lienhard, Cosima Suter, Thomas Pabst, Felicitas Hitz, Jakob R. Passweg, Olivier Spertini, Nathan Cantoni, Daniel Betticher, Lucas Simeon, Michael Medinger, Stefanie Hayoz, Adrian Schmidt

“… INTRODUCTION: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a very rare disease, with unique diagnostic challenges and often dismal outcome. There are no widely accepted treatment guidelines available. …”
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An early lung cancer diagnosis model for non-smokers incorporating ct imaging analysis and circulating genetically abnormal cells (CACs) by Ran Ni, Yongjie Huang, Lei Wang, Hongjie Chen, Guorui Zhang, Yali Yu, Yinglan Kuang, Yuyan Tang, Xing Lu, Hong Liu

“…Furthermore, our results indicated that the model built using random forest (RF) method, which integrates clinical characteristics (age, extra-thoracic cancer history, gender), radiological characteristics of pulmonary nodules (nodule diameter, nodule count, upper lobe location, malignant sign at the nodule edge, subsolid status), the artificial intelligence analysis of LDCT data, and liquid biopsy achieved the best diagnostic performance in the independent external non-smokers validation cohort (sensitivity 92%, specificity 97%, area under the curve [AUC] = 0.99). …”
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Dual-Stage AI Model for Enhanced CT Imaging: Precision Segmentation of Kidney and Tumors by Nalan Karunanayake, Lin Lu, Hao Yang, Pengfei Geng, Oguz Akin, Helena Furberg, Lawrence H. Schwartz, Binsheng Zhao

“…This underscores the model’s significant potential for clinical integration, offering enhanced diagnostic precision and reliability in radiological assessments.…”
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Association between the intake of potentially risky beverages and the occurrence of endometrial polyps: a case–control study by Rui Fu, Rui Fu, Shipeng Zhang, Shipeng Zhang, Chang Cai, Chang Cai, Xiaocui Wang, Xiaocui Wang, Yanjie Jiang, Xiulian Zhuang, Xiulian Zhuang, Jiating Zhang, Xiaoli Ji, Chengcheng Yang

“…The case group consisted of patients who visited the gynecological clinic at the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine and were diagnosed with endometrial polyps (Eps) based on international diagnostic criteria. The control group consisted of women of childbearing age who visited the gynecological clinic with similar clinical symptoms but did not have EPs. …”
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Nomogram to screen older adult patients attending the radiology department for sarcopenia by Guiying Yuan, Guoxi Ye, Jianguang Hu, Huimin Hu, Chanmei Shi, Ye Zhang, Junbing Huang, Zhiqiong Li, Xuwen Zeng, Rongshao Tan, Yuchao Xiong

“…The DeLong test showed that the diagnostic efficacy of the joint model was significantly higher than that of CC, SARC-F, MUAC, and SARC-CalF. …”
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Molecular genetic diagnosis and surgical management in a cohort of children with 46,XY disorders/differences of sex development by Yuenshan Sammi Wong, Yuenshan Sammi Wong, Ho Ming Luk, Ho Chung Yau, Lap Ming Wong, Sarah Wing Yiu Poon, Joanna Yuet Ling Tung, Yuk Him Tam, Yuk Him Tam

“…Of the whole group, seven patients were found to inherit genetic alterations from their parents.ConclusionsMolecular genetic diagnosis enhances the understanding of etiology, improves diagnostic accuracy, and provides precise guidance in the counseling and surgical management of children with 46,XY DSD.…”
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Molecular, Cytogenetic, and Hematological Analysis of Chronic Myeloid Leukemia Patients and Discovery of Two Novel Translocations by Muhammad Asif, Abrar Hussain, Abdul Wali, Nazeer Ahmed, Irfan Ali, Zafar Iqbal, Muhammad Amir, Muhammad Shafiq, Mahmood Rasool

“…FISH was performed on 38 patients for diagnostic purposes and on 39 patients for monitoring purposes. …”
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Integrating bulk and single-cell RNA sequencing data: unveiling RNA methylation and autophagy-related signatures in chronic obstructive pulmonary disease patients by Shi-Xia Liao, Lan-Ying Zhang, Ling-Mei Shi, Huai-Yu Hu, Yan-Hui Gu, Ting-Hua Wang, Yao Ouyang, Peng-Peng Sun

“…These findings provide novel genetic insights into the epigenetic mechanisms of COPD and suggest potential avenues for developing diagnostic and therapeutic strategies.…”
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Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology by Iryna Omelianenko, Iryna Omelianenko, Nazarii Kobyliak, Nazarii Kobyliak, Tetyana Falalyeyeva, Tetyana Falalyeyeva, Oleksii Seleznov, Pavlina Botsun, Lyudmila Ostapchenko, Oleksandr Korotkyi, Liudmyla Domylivska, Olena Tsyryuk, Galyna Mykhalchyshyn, Tetiana Shapochka, Oksana Sulaieva, Oksana Sulaieva

“…The number of immune cells in thyroid cytology samples could be an additional criterion in cytological diagnostics for III-V Bethesda categories. Further investigations are needed to validate the findings of the study.…”
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Genetic and peripheral biomarkers of comorbid posttraumatic stress disorder and traumatic brain injury: a systematic review by Kiriana Cowansage, Reshmi Nair, Jose M. Lara-Ruiz, Daniel E. Berman, Courtney C. Boyd, Tiffany L. Milligan, Daniel Kotzab, Dawn M. Bellanti, Lisa M. Shank, Maria A. Morgan, Derek J. Smolenski, Ida Babakhanyan, Nancy A. Skopp, Daniel P. Evatt, Marija S. Kelber

“…Additional research is needed to determine how such factors indicate, predict, and contribute to comorbidity and to what extent they represent viable targets for the development of novel diagnostic tools and therapeutic interventions.…”
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Use of artificial intelligence for gestational age estimation: a systematic review and meta-analysis by Sabahat Naz, Sahir Noorani, Syed Ali Jaffar Zaidi, Abdu R. Rahman, Saima Sattar, Jai K. Das, Jai K. Das, Zahra Hoodbhoy

“…Risk of bias assessment was performed using Quality Assessment for Diagnostic Accuracy Studies-2 (QUADAS-2) tool. Mean error in GA was estimated using STATA version-17 and subgroup analysis on trimester of GA assessment, AI models, study design, and external validation was performed.ResultsOut of the 1,039 studies screened, 17 were included in the review, and of these 10 studies were included in the meta-analysis. …”
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Potential of 6-mm-diameter fully covered self-expandable metal stents for unresectable malignant distal biliary obstruction: a propensity score-matched study by Daiki Yamashige, Susumu Hijioka, Yoshikuni Nagashio, Yuta Maruki, Soma Fukuda, Shin Yagi, Kohei Okamoto, Hidenobu Hara, Yuya Hagiwara, Daiki Agarie, Tetsuro Takasaki, Akihiro Ohba, Shunsuke Kondo, Chigusa Morizane, Hideki Ueno, Miyuki Sone, Yutaka Saito, Takuji Okusaka

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End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence by Wojciech Ciezobka, Joan Falco-Roget, Cemal Koba, Alessandro Crimi

“…Stroke is one of the leading causes of mortality and morbidity worldwide, and it demands precise diagnostic tools for timely intervention and improved patient outcomes. …”
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Diagnosis and Treatment of Postoperative Myocardial Infarction: A Retrospective Cohort Study on 600 Cardiac Surgery Patients by Saimir Kuci, Marsela Goga, Alfred Ibrahimi, Ervin Bejko, Stavri Llazo, Jonela Burimi, Esmerilda Bulku, Andi Kacani, Ermal Likaj, Ali Refatllari, Selman Dumani, Klodian Krakulli, Arber Aliu, Fjorba Mana, Devis Pellumbi, Aferdita Veseli, Edlira Rruci, Laureta Dibra, Arben Baboci, Edvin Prifti, Altin Veshti

“…The incidence, diagnosis, and management of PMI were evaluated, focusing on diagnostic methods, therapeutic interventions, and the role of intra-aortic balloon pumps (IABPs). …”
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The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis by Zhihui Xu, Cong Liu, Peng Wang, Xing Wang, Yuzhang Li

“…Conclusion Based on the International Classification of Diseases (ICD) and the Diagnostic and Statistical Manual of Mental Disorders (DSM) classification systems, a research framework for exercise interventions on executive function in MDD patients was constructed, demonstrating that exercise can improve inhibitory function in MDD with high evidence quality. …”
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DEVELOPING INFORMATION AND TECHNOLOGICAL COMPETENCE OF PROSPECTIVE MILITARY SAILORS by Ruslan Shevchenko, Oleh Cherniavskyi, Vasyl Shemchuk, Olena Zlobina, Natalia Benkovska, Nataliia Terentieva, Андрій Гуралюк

“…With the help of a comparative analysis based on the results of two diagnostic sections, the statistical reliability of the differences in the signs of identifying IT competence criteria before and after the training of future officers of the Ukrainian Navy was determined Considering the unique dynamics within a maritime institution of higher education, a systematic blend of lectures, discussions, practical training sessions, situational exercises, utilization of virtual technologies, and the undertaking of group and individual projects significantly elevated the level of information technology competence among future Naval Forces officers. …”
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Investigation of 23 Bile Acids in Liver Bile in Benign and Malignant Biliary Stenosis: A Pilot Study by Stanislav Rejchrt, Milos Hroch, Rudolf Repak, Tomas Fejfar, Tomas Douda, Darina Kohoutova, Eva Peterova, Jan Bures

“…More patients need to be enrolled in further studies so that the real diagnostic yield of bile acids can be determined.…”
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The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…The correlation between hematological indicators and tumor-node-metastasis (TNM) stage was assessed through Spearman’s analysis.Results: Eligible patients and healthy controls were grouped by gender. The diagnostic ability of PNI was significantly superior to other indicators to diagnose male GC (area under the curve [AUC]=0.908, 95% CI: 0.892– 0.925) and female GC (AUC=0.890, 95% CI: 0.865– 0.914). …”
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