Consequences of Repetitive Head-Impact Exposure in Sports - literature review by Wiktoria Gajek-Flanczewska, Sebastian Flanczewski, Małgorzata Wirkijowska, Katarzyna Wójtowicz, Jakub Wirkijowski, Agata Walczak, Paulina Woźniak, Ewa Wietrzykowska, Dominika Sobolewska, Katarzyna Michalczyk-Fraszka, Martyna Śliwińska, Anna Podraza

“…The review emphasizes the need for better diagnostic tools, injury prevention strategies, and patient-centered decision-making to protect athletes. …”
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A Case of Primary Lung Adenocarcinoma With Recurrent Brain Metastasis due to Transformation to Small Cell Carcinoma During Adjuvant Atezolizumab Therapy by Nao Kobayashi, Noriaki Sunaga, Masakiyo Yatomi, Ikuo Wakamatsu, Sohei Muto, Hayato Ikota, Rei Yamaguchi, Yoichi Ohtaki, Toshiteru Nagashima, Nobuteru Kubo, Tomomi Masuda, Yosuke Miura, Hiroaki Tsurumaki, Reiko Sakurai, Yasuhiko Koga, Takeshi Hisada, Toshitaka Maeno

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A Prospective Study of Tuberculosis Drug Susceptibility in Sabah, Malaysia, and an Algorithm for Management of Isoniazid Resistance by Muhammad Redzwan S. Rashid Ali, Uma Parameswaran, Timothy William, Elspeth Bird, Christopher S. Wilkes, Wai Khew Lee, Tsin Wen Yeo, Nicholas M. Anstey, Anna P. Ralph

“…However, INH-resistance poses challenges, and NTM is an important differential diagnosis in this setting, where smear microscopy is the usual diagnostic modality. To address INH-R management issues in our setting, we propose an algorithm for the treatment of isoniazid-resistant PTB.…”
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aPD-L1-facilitated theranostic and tumor microenvironment remodeling of pancreatic cancer via docetaxel-loaded phase-transformation nanoparticles triggered by low-intensity pulsed... by Yi Tang, Qingling Shen, Peng Lin, Zhixin Chen, Denghui Fan, Minling Zhuo, Yajiao Gan, Yixi Su, Qingfu Qian, Liwu Lin, Ensheng Xue, Zhikui Chen

“…Upon exposure to low-intensity pulsed ultrasound (LIPUS) stimulation, the NPs underwent a phase transformation to form microbubbles with substantial molecular ultrasound diagnostic effects, and combined treatment resulted in a tumor growth inhibition rate of 88.91%. …”
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Investigating the role of cathepsins in breast cancer progression: a Mendelian randomization study by Shengyi Zhou, Shengyi Zhou, Shengyi Zhou, Yizhou Sun, Yizhou Sun, Wenzhang Zha, Wenzhang Zha, Guangjun Zhou, Guangjun Zhou

“…Cathepsin Z can mediate the effects of PRX, CRY2, ADCY3, and PELATON on in situ breast cancer.DiscussionThese findings highlight the dual roles of cathepsins as potential risk and protective factors for breast cancer, underscoring their potential in diagnostic and therapeutic strategies.…”
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Utility of Ascitic Fluid Adenosine Deaminase Levels in the Diagnosis of Tuberculous Peritonitis in General Medical Practice by Ayako Kumabe, Shuji Hatakeyama, Naoki Kanda, Yu Yamamoto, Masami Matsumura

“…This study aimed to investigate the sensitivity and specificity of elevated adenosine deaminase (ADA) levels as a diagnostic marker for tuberculous peritonitis. Methods. …”
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Deep learning–assisted diagnosis of acute mesenteric ischemia based on CT angiography images by Lei Song, Xuesong Zhang, Jian Zhang, Jie Wu, Jinkai Wang, Feng Wang

“…DCA indicated that the Fusion Model provided a greater net benefit than those of models based solely on imaging and clinical information across the majority of the reasonable threshold probabilities.ConclusionThe incorporation of CTA images and clinical information into the model markedly enhances the diagnostic accuracy and efficiency of AMI. This approach provides a reliable tool for the early diagnosis of AMI and the subsequent implementation of appropriate clinical intervention.…”
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Precision fetal cardiology detects cyanotic congenital heart disease using maternal saliva metabolome and artificial intelligence by Ray Bahado-Singh, Nadia Ashrafi, Amin Ibrahim, Buket Aydas, Ali Yilmaz, Perry Friedman, Stewart F. Graham, Onur Turkoglu

“…Abstract Prenatal sonographic diagnosis of congenital heart disease (CHD) can lead to improved morbidity and mortality. However, the diagnostic accuracy of ultrasound, the sole prenatal screening tool, remains limited. …”
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Application of the 2021 AAPOS Guidelines in Clinics with Revision and Validation of SPOT Referral Criteria by Li R, Yan Q, Lin X, Wu Z, Zhu H, Guo W, Zhang P, Zuo F, Wu Z, Liu H, Huang D

“…These results were compared to the age-based 2021 AAPOS diagnostic thresholds. Additionally, this study validated previously reported referral criteria within its population.Results: The study involved 1103 children (347 below four years; 756 aged four years and above). …”
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Late-onset first epileptic seizure and cerebral small vessel disease: role of juxtacortical white matter lesions by Adrian Nasca, Adrian Nasca, Leo Sokolovič, Leo Sokolovič, Oliver Koprda, Patrick Haage, Patrick Haage, Thorsten Schmidt, Juraj Kukolja, Juraj Kukolja

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Hiperurisemia pada Pra Diabetes by Ellyza Nasrul, Sofitri .

“…<br />Hyperuricemia is a state in the blood uric acid levels over 7.0 mg / dL.Pre-diabetes is a subject which has a plasma<br />glucose level will rise but the increase is still not reached the minimum value for the diagnostic criteria for diabetes<br />mellitus (DM). …”
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Molecular genetic and bacteriological methods of bovine mycoplasmosis diagnosis by E. V. Remizova, A. V. Gorbatov, L. K. Semina, Z. A. Skulyabina, N. V. Shmidt, G. A. Baldicheva, N. N. Avduevskaya

“…Real-time polymerase chain reaction is undoubtedly the most accurate and rapid diagnostic method for mycoplasmosis, but a preliminary diagnosis can also be established bacteriologically within 2–7 days. …”
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Temporal Analysis of the Incidence, Mortality and Disability-Adjusted Life Years of Benign Gallbladder and Biliary Diseases in High-Income Nations, 1990–2019 by Dominic W. Proctor, BMBS, MSc, Richard Goodall, BSc, MBChB, MRCS, FHEA, Kim Borsky, MBBS, MMRCS, Justin D. Salciccioli, MBBS, MA, Dominic C. Marshall, MBBS, MRCP, BSc, Kumaran Shanmugarajah, MD, PhD, Joseph Shalhoub, BSc, MBBS, FHEA, PhD, DIC, MEd, FFSTEd, FRCS, FEBVS

“…International variation in lifestyle factors, diagnostic and management strategies likely account for national and sex disparities. …”
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Clinical and Technical Characteristics of Coronary Angiography and Percutaneous Coronary Interventions Performed before and after Transcatheter Aortic Valve Replacement with a Ball... by Alfredo Nunes Ferreira-Neto, Rishi Puri, Lluis Asmarats, Victoria Vilalta, Leonardo Guimaraes, Robert Delarochellière, Jean-Michel Paradis, Siamak Mohammadi, Eric Dumont, Josep Rodés-Cabau

“…Neither CAs‐nor PCIs‐performed after valve implantation revealed significant differences regarding arterial access site, catheter diameter, number of diagnostic or guiding catheters used, procedural duration, fluoroscopy time, or achievement of selective coronary injection. …”
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High Seroprevalence of Autoantibodies Typical of Autoimmune Liver Disease in Eastern Ethiopia: Is Chewing of Khat (Catha edulis) a Triggering Factor? by Stian Magnus Staurung Orlien, Tekabe Abdosh Ahmed, Nejib Yusuf Ismael, Nega Berhe, Trine Lauritzen, Svein Gunnar Gundersen, Asgeir Johannessen

“…However, the seroprevalences of AMA and SMA were strikingly high in this Ethiopian population compared to global estimates, suggesting that diagnostic algorithms for autoimmune liver diseases developed in Europe and North America might lead to misdiagnosis of patients on the African continent.…”
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Significant Calcification of an Entire Aortic Tree with Renal Artery Subocclusion: Acute Kidney Injury, Ischemic Kidney Disease, and the Tissue Viability Question—A Case Report by Marko Baralić, Selena Gajić, Aleksandra Kezić, Ana Bontić, Jelena Pavlović, Voin Brković, Vidna Karadžić Ristanović, Danka Bjelić, Maja Životić, Sanja Radojević-Škodrić, Želimir Antonić, Nenad Ilijevski, Milan Radović

“…To obtain an accurate diagnosis, it is crucial to recognize the symptoms and signs suggesting renal artery stenosis (RAS) and perform appropriate diagnostic and treatment procedures afterward. Case Presentation: We present a case of a 60-year-old female patient with hypertensive crisis, acute heart failure (HF), and pulmonary edema as the initial signs of acute kidney injury (AKI) caused by right RAS and left renal artery occlusion in the presence of severe aortic atherosclerosis revealed on computed tomography angiography (CTA) of the abdomen. …”
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Targeting Liver Biopsies For Optimal Biopsy Site In Diffused Liver Disease Using Real-Time Shear Wave Elastography: A Prospective, Single Center Study by Naushaba Malik, Shahbakht Aftab, Rida Noor, Noor Aftab, Rizwan, Rehan

“… Objective: The study aimed to pinpoint the precise site for liver biopsy using ultrasound and elastography guidance and to assess and compare the diagnostic accuracy of shear wave elastography (SWE) and transient elastography (TE) through histopathological correlation. …”
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Measles and Pregnancy: Immunity and Immunization—What Can Be Learned from Observing Complications during an Epidemic Year by Rosalia Ragusa, Armando Platania, Mario Cuccia, Gaetano Zappalà, Gabriele Giorgianni, Placido D’Agati, Maria Alessandra Bellia, Marina Marranzano

“…We controlled hospital discharge records for patients admitted to hospital obstetric wards searching the measles diagnostic code. We have indicated the case as “confirmed” when the IgM was found to be positive with the ELISA method. …”
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Correlation Between Vestibular Disorders and Superior Semicircular Dehiscence on High-resolution Computed Tomography at Tam Anh Ho Chi Minh General Hospital by Cong Trinh TRAN, Thi Lan Huong LE, Tran Thi Thuy HANG, Nghi Hai MA, Ho Hoang PHUONG, Tran Phanchung THUY

“…Conclusions: These findings highlight the importance of considering SSCD as a potential etiology in patients presenting with vestibular symptoms and emphasize the diagnostic utility of HRCT.…”
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Quantifying intratumoral biomarker heterogeneity in tubo-ovarian high-grade serous carcinoma to optimize clinical translation by Aline Talhouk, Derek S. Chiu, Liliane Meunier, Kurosh Rahimi, Cécile Le Page, Monique Bernard, Diane Provencher, David G. Huntsman, Anne Marie Mes Masson, Martin Köbel

“…We quantified the ITH of six clinically used immunohistochemical diagnostic and prognostic biomarkers (WT1, p53, p16, PR, CD8, and Ki67). …”
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