Tongue squamous cell carcinoma-targeting Au-HN-1 nanosystem for CT imaging and photothermal therapy by Ming Hao, Xingchen Li, Xinxin Zhang, Boqiang Tao, He Shi, Jianing Wu, Yuyang Li, Xiang Li, Shuangji Li, Han Wu, Jingcheng Xiang, Dongxu Wang, Weiwei Liu, Guoqing Wang

“…Nanoparticles with diagnostic and photothermal therapeutic properties may offer a new approach for the targeted therapy of TSCC. …”
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Retinal Microperimetry as a Novel Tool for Early Detection of Subclinical Cognitive Dysfunction and Brain Damage in Type 1 Diabetes: A Pilot Study by Manel Mateu‐Salat, Nicole Stanton‐Yonge, Frederic Sampedro Santaló, José Ignacio Vela, Jesús Díaz Cascajosa, Eva Safont Pérez, Daniela Rego‐Lorca, Ana Chico

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[18F]FDG PET-Based Radiomics and Machine Learning for the Assessment of Gliomas and Glioblastomas: A Systematic Review by Francesco Dondi, Roberto Gatta, Maria Gazzilli, Pietro Bellini, Gian Luca Viganò, Cristina Ferrari, Antonio Rosario Pisani, Giuseppe Rubini, Francesco Bertagna

“…Signatures, including radiomics analysis and ML, generally demonstrated a possible diagnostic value to assess different characteristics of gliomas and GBMs, such as the methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) promoter, the isocitrate dehydrogenase (IDH) genotype, alpha thalassemia/mental retardation X-linked (ATRX) mutation status, proliferative activity, differential diagnosis with solitary brain metastases or primary central nervous system lymphoma, and prognosis of these patients. …”
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A systematic review of the worldwide prevalence of survivors of poliomyelitis reported in 31 studies by Alice Theadom, Shivanthi Balalla, Kelly M Jones, Valery L Feigin, Gordon Jackman

“…We aim to undertake a systematic review of all literature concerning the prevalence of survivors of poliomyelitis.Methods Electronic databases were searched from 1900 up to May 2016 for peer-reviewed studies using a population-based approach witha defined denominator and some form of diagnostic or clinical verification of polio. Exclusion criteria were any prevalence data that were unable to be extracted or calculated and studies reporting on incidence only. …”
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SARS-CoV-2 Evolution: Implications for Diagnosis, Treatment, Vaccine Effectiveness and Development by Fabrizio Angius, Silvia Puxeddu, Silvio Zaimi, Serena Canton, Sepehr Nematollahzadeh, Andrea Pibiri, Ilenia Delogu, Gualtiero Alvisi, Meng Ling Moi, Aldo Manzin

“…In the past four years, immense research efforts have contributed much to our understanding of the viral pathogenesis mechanism, the COVID-19 syndrome, and the host–microbe interactions, leading to the development of effective vaccines, diagnostic tools, and treatments. The focus of this review is to provide a comprehensive analysis of the functional impact of mutations on diagnosis, treatments, and vaccine effectiveness. …”
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High HLA-F Expression Is a Poor Prognosis Factor in Patients with Nasopharyngeal Carcinoma by Bo Wu, Haihua Yang, Shenpeng Ying, Hongsheng Lu, Wei Wang, Jiaming Lv, Huacai Xiong, Wei Hu

“…Additional studies using larger sample sizes may be necessary to determine whether sHLA-F is a feasible NPC diagnostic indicator.…”
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Endoscopic Analysis of Microstructures of the Colon Mucosa on the Edge of the Post-Resection Defect as a Measure of Preventing Recurrence of Polyps after a Cold Polypectomy by N. V. Ageykina, N. A. Oleynikova, P. G. Malkov, N. V. Danilova, O. A. Kharlova, Yu. M. Korolev, E. D. Fedorov

“…In the endoscopic diagnosis of the vascular pattern of the colon mucosa was determined that flat-elevated polyps have a fine capillary network, which reduces the risk of bleeding when use a cold resection method. An observation (diagnostic colonoscopy) was performed in 11 (10.7 %) patients, including a case with the polyp with high grade displasia. …”
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Assessing the Relationship Between the Type of Internet Use and Internet Addiction in Early and Middle Adolescents: Cross-Sectional Study From Qatar by Khansa Chemnad, Maryam Aziz, Sanaa Al- Harahsheh, Azza Abdelmoneium, Ahmed Baghdady, Diana Alsayed Hassan, Raian Ali

“…The survey measured essential and nonessential internet use, subjective happiness with nonessential use, and IA symptoms using the Internet Addiction Diagnostic Questionnaire, as well as participant demographics. …”
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Gaps in Study Design for Immune Parameter Research for Latent Tuberculosis Infection: A Systematic Review by Mariana Herrera, Cristian Vera, Yoav Keynan, Zulma Vanessa Rueda

“…Participants’ information, diagnostic criteria, IP, detection methods, and biases were collected. …”
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Developing non-invasive molecular markers for early risk assessment of Alzheimer's disease by Tapas K. Sur, Tanmoy Mondal, Zarish Noreen, Jheannelle Johnson, Gail Nunlee-Bland, Christopher A. Loffredo, Brent E. Korba, Vijay Chandra, Siddhartha S. Jana, Bernard Kwabi-Addo, Sumit Sarkar, Somiranjan Ghosh

“…Current improvements have unveiled the disease's pathophysiology and clinical diagnostic tests, targeting the neurological changes (neurodegeneration, amyloid precursor protein metabolism and tangle pathology) with precise PET/MRI imaging and xMAP/SIMOA (Multiplex simultaneous detection/single molecule array) to identify and quantify β-amyloids (Aβ40, Aβ42), total tau (T-tau) and phosphorylated tau (P-tau) proteins in the brain and cerebrospinal fluid (CSF) of patients. …”
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Real-time seizure detection in paediatric intensive care patients: the RESET child brain protocol by Kristen Gibbons, Andreas Schibler, Anthony Slater, Louise Sparkes, Michaela Waak, Stephen Malone, Jane Harnischfeger, Sandra Gurr

“…The primary aim of this study is to describe accuracy of interpretation of QEEG trends by paediatric intensive care unit (PICU) nurses compared with cEEG assessment by neurologist (standard clinical care) in children at risk of seizures and status epilepticus utilising diagnostic test statistics. The secondary aims are to determine time to seizure detection for QEEG users compared with standard clinical care and describe impact of confounders on accuracy of seizure detection.Methods and analysis This will be a single-centre, prospective observational cohort study evaluating a paediatric QEEG programme utilising the full 19 electrode set. …”
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Biological significance of soluble IL-2 receptor by Calogero Caruso, Giuseppina Candore, Diego Cigna, Antonio Tobia Colucci, Maria Assunta Modica

“…Since many conditions may influence sIL-2R production, little diagnostic use may result from these measurements. However, since blood sIL-2R levels may correlate with disease progression and/or response to therapy, their measurement may be a useful index of activity and extent of disease. …”
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New inflammatory markers associated with disease activity in rheumatoid arthritis: pan-immune-inflammation value, systemic immune-inflammation index, and systemic inflammation resp... by İpek Okutan, Recai Aci, Âdem Keskin, Melek Bilgin, Halit Kızılet

“…Conclusions The findings revealed that PIV, SII, and SIRI were elevated in individuals with RA and may serve as complementary diagnostic markers. PIV, SII, and SIRI, as measures of disease activity in RA, may help monitor treatment efficacy and improve patient prognosis.…”
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Tuberculosis and COVID-19: Lessons from the Past Viral Outbreaks and Possible Future Outcomes by Radu Crisan-Dabija, Cristina Grigorescu, Cristina-Alice Pavel, Bogdan Artene, Iolanda Valentina Popa, Andrei Cernomaz, Alexandru Burlacu

“…Finally, we addressed the issues of vaccination and diagnostic reliability in the context of coinfection. …”
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Performance evaluation of nine reference centers and comparison of DNA extraction protocols for effective surveillance of Leishmania-infected Phlebotomine sand flies: Basis for tec... by Jorian Prudhomme, Aymeric Delabarre, Bulent Alten, Umut Berberoglu, Eduardo Berriatua, Gioia Bongiorno, José Manuel Cristovao, Maya Davidovich-Cohen, Trentina Di Muccio, Ozge Erisoz Kasap, Eleonora Fiorentino, Oscar D Kirstein, Edwin Kniha, Carla Maia, Mesut Mungan, Clara Muñoz-Hernández, Muhammed Nalçaci, Gizem Oguz Kaskan, Yusuf Ozbel, Seray Ozensoy Toz, Ricardo Parreira, Katharina Platzgummer, Ceylan Polat, José Risueño, Liora Studentsky, Gamze Varol, Julia Walochnik, Kardelen Yetişmiş, Florence Robert-Gangneux

“…All but one center detected all concentrations, demonstrating strong diagnostic proficiency. The ability to detect low concentrations highlighted the robustness of the qPCR assay used, though variations in Cq values indicated differences in sensitivity related to technical capabilities or DNA extraction kit performance. …”
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A Comprehensive Review of Artificial Intelligence (AI) Applications in Pulmonary Hypertension (PH) by Sogol Attaripour Esfahani, Nima Baba Ali, Juan M. Farina, Isabel G. Scalia, Milagros Pereyra, Mohammed Tiseer Abbas, Niloofar Javadi, Nadera N. Bismee, Fatmaelzahraa E. Abdelfattah, Kamal Awad, Omar H. Ibrahim, Hesham Sheashaa, Timothy Barry, Robert L. Scott, Chadi Ayoub, Reza Arsanjani

“…<i>Background:</i> Pulmonary hypertension (PH) is a complex condition associated with significant morbidity and mortality. Traditional diagnostic and management approaches for PH often face limitations, leading to delays in diagnosis and potentially suboptimal treatment outcomes. …”
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Chromothripsis in Treatment Resistance in Multiple Myeloma by Kyoung Joo Lee, Ki Hong Lee, Kyong-Ah Yoon, Ji Yeon Sohn, Eunyoung Lee, Hyewon Lee, Hyeon-Seok Eom, Sun-Young Kong

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Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B by Guangyue Yang, Liping Zhuang, Tiantian Sun, Yee Hui Yeo, Le Tao, Wei Zhang, Wenting Ma, Liu Wu, Zongguo Yang, Yanqin Yang, Dongying Xue, Jie Zhang, Rilu Feng, Ebert Matthias P., Steven Dooley, Ekihiro Seki, Ping Liu, Cheng Liu

“…A total of 735 patients from two medical centers (385 CHB patients and 350 healthy controls) were included to determine the association of serum and tissue GDNF levels with biopsy-proven cirrhosis. The diagnostic accuracy of serum GDNF (sGDNF) was estimated and compared with other indices of cirrhosis. …”
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Therapeutic Drug Monitoring-Guided Linezolid Therapy for the Treatment of Multiple Staphylococcal Brain Abscesses in a 3-Month-Old Infant by Anna Cascone, Maia De Luca, Raffaele Simeoli, Bianca Maria Goffredo, Laura Cursi, Costanza Tripiciano, Lorenza Romani, Stefania Mercadante, Martina Di Giuseppe, Francesca Ippolita Calo Carducci, Davide Luglietto, Paola Bernaschi, Laura Lancella

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Image-Based Detection and Classification of Malaria Parasites and Leukocytes with Quality Assessment of Romanowsky-Stained Blood Smears by Jhonathan Sora-Cardenas, Wendy M. Fong-Amaris, Cesar A. Salazar-Centeno, Alejandro Castañeda, Oscar D. Martínez-Bernal, Daniel R. Suárez, Carol Martínez

“…This system’s adaptability to low-resource settings underscores its potential to improve malaria diagnostics globally.…”
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