An Unsuspected Finding of t(9;22): A Rare Case of Philadelphia Chromosome-Positive B-Lymphoblastic Lymphoma by Prajwal Boddu, C. Cameron Yin, Rashmi Kanagal-Shamanna, Guillin Tang, Beenu Thakral, Tapan Kadia, Marina Konopleva, Elias Jabbour, Nitin Jain

“…During this time, fluorescence in situ hybridization (FISH) and PCR testing for BCR-ABL1 rearrangements were being performed on the marrow specimens as a part of routine diagnostic workup. While the FISH returned negative, PCR testing unexpectedly detected BCR-ABL1 fusion transcripts at a low level of 0.48%. …”
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OCT-based diagnosis of glaucoma and glaucoma stages using explainable machine learning by Md Mahmudul Hasan, Jack Phu, Henrietta Wang, Arcot Sowmya, Michael Kalloniatis, Erik Meijering

“…However, current automated diagnostic approaches on Glaucoma diagnosis solely rely on black-box deep learning models, lacking explainability and trustworthiness. …”
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Application of Anterior Segment Optical Coherence Tomography in Pediatric Ophthalmology by Ricardo Salles Cauduro, Caroline do Amaral Ferraz, Maira Saad Ávila Morales, Patricia Novita Garcia, Yara Cristina Lopes, Paulo Henrique Souza, Norma Allemann

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Involvement of Russian student youth in Internet communications as a factor in the formation of models of their socio-political activity by E. A. Istyagina-Yeliseeva, C. E. Barijenikova, A. V. Boldyreva

“…Using the calculation of indices, determining measures of Central trend and variation, as well as other quantitative and qualitative diagnostic tools, a comparative analysis of the results of various sociological studies on the relationship between the level of youth involvement in the Internet space and the degree of political activity has been carried out. …”
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Molecular network analysis for detecting HIV transmission clusters: insights and implications by Yangyang Liu, Lichun Hua, Wenqian Wu, You Ge, Wei Li, Pingmin Wei

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Oral Cancer Awareness and Knowledge in the City of Valongo, Portugal by Luís Silva Monteiro, Filomena Salazar, Júlio Pacheco, Saman Warnakulasuriya

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Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome by Simona Mihai, Elena Codrici, Ionela Daniela Popescu, Ana-Maria Enciu, Lucian Albulescu, Laura Georgiana Necula, Cristina Mambet, Gabriela Anton, Cristiana Tanase

“…In this scenario, a huge step forward was made by the increasing progression of omics approaches, specially designed for identification of biomarkers useful for early diagnostic and follow-up. Recent omics advances could provide novel insights in deciphering the disease pathophysiology; thus, identification of circulating biomarker panels using state-of-the-art proteomic technologies could improve CKD early diagnosis, monitoring, and prognostics. …”
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High Serum Adipocyte Fatty Acid Binding Protein Is Associated with Metabolic Syndrome in Patients with Type 2 Diabetes by Jer-Chuan Li, Du-An Wu, Jia-Sian Hou, Yi-Maun Subeq, Hsin-Dean Chen, Bang-Gee Hsu

“…MetS and its components were defined using diagnostic criteria from the International Diabetes Federation. …”
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Risk of second primary malignancies among survivors of cutaneous melanoma: A nationwide population-based study in the Republic of Korea by Joon Min Jung, Do Hyung Kim, Ye-Jee Kim, Ik Jun Moon, Woo Jin Lee, Sung Eun Chang, Mi Woo Lee, Chong Hyun Won

“…Inherent uncertainty related to diagnostic codes may exist. The risk of overall and specific SPMs was significantly elevated in Asian melanoma survivors, particularly among those with invasive melanoma. …”
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Composite Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and T-Prolymphocytic Leukemia Presenting with Lymphocytosis, Skin Lesions, and Generalized Lymphadenopathy by Ali Sakhdari, Guilin Tang, Lawrence E. Ginsberg, Cheryl F. Hirsch-Ginsberg, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros, Roberto N. Miranda

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MicroRNA-29b Suppresses Inflammation and Protects Blood-Brain Barrier Integrity in Ischemic Stroke by Xiaoqing Ma, Ho Jun Yun, Kenneth Elkin, Yunliang Guo, Yuchuan Ding, Guangwen Li

“…Results. miR-29b levels in neutrophils were found to be significantly lower in stroke patients compared with healthy controls, which may indicate its high diagnostic sensitivity and specificity for stroke. Moreover, miR-29b levels in leukocytes showed a negative correlation with National Institute of Health Stroke Scale (NIHSS) scores and C1QTNF6 levels. …”
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Mild Clinical Course of Severe Fever with Thrombocytopenia Syndrome Virus Infection in an Elderly Japanese Patient by Yuko Ohagi, Shinobu Tamura, Chiaki Nakamoto, Hiromichi Nakamoto, Masayuki Saijo, Masayuki Shimojima, Yoshio Nakano, Tokuzo Fujimoto

“…Although not completely fulfilling the diagnostic criteria used in a retrospective study in Japan, SFTS was suspected, and we detected SFTS virus in the patient’s blood using RT-PCR. …”
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The Performance qualification of automatic volumetric pipettes used in university hospitals in the DRC: Case of Kinshasa, Bukavu, and Kisangani by Joenna Bapite Musongiela, Jocelyn Mankulu Kakumba, Emile Tweni Baruti, Timothé Mavanga Mabaya, Jacquie Bolavie Bolande, Sara Munguakonkwa Byamungu, Jérémie Mbinze Kindenge

“… Introduction Automatic micropipettes are widely used in clinical biology for quantitative analyses in medical diagnostics. However, in many hospitals in developing countries, this equipment is often not verified for accuracy in collecting biological sample volumes. …”
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A risk prediction score to identify patients at low risk for COVID-19 infection by Wui Mei Chew, Chee Hong Loh, Aditi Jalali, Grace Shi En Fong, Loshini Senthil Kumar, Rachel Hui Zhen Sim, Russell Pinxue Tan, Sunil Ravinder Gill, Trilene Ruiting Liang, Jansen Meng Kwang Koh, Tunn Ren Tay

“…Both models had good diagnostic performance with areas under the receiver operating characteristic curve of 0.934 and 0.866, respectively. …”
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Idiopathic giant cell myocarditis or cardiac sarcoidosis? A retrospective audit of a nationwide case series by Kaj Ekström, Anne Räisänen‐Sokolowski, Jukka Lehtonen, Hanna‐Kaisa Nordenswan, Mikko I. Mäyränpää, Markku Kupari

“…Finding granulomas in or outside the heart was considered diagnostic of CS and exclusive of GCM. Altogether 45 of the 73 cases of GCM (62%) were reclassified as CS. …”
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Comparison of Atrial Fibrillation in the Young versus That in the Elderly: A Review by Rajiv Sankaranarayanan, Graeme Kirkwood, Katharine Dibb, Clifford J. Garratt

“…Moreover with availability of improved and modern investigational and diagnostic techniques, novel causes of AF are being reported thereby seemingly consigning the diagnosis of “lone AF” to a rather mythical existence. …”
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BioFire FilmArray Blood Culture Identification (BCID) Panel and Clinical Usefulness: A Systematic Review by Niti Gor, Devesh Joshi

“…Introduction: In the critical care of septic patients, timely and accurate diagnosis is paramount. Molecular diagnostic studies that offer rapid and precise results are lacking. …”
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Assessment of Angiography-Based Renal Quantitative Flow Ratio Measurement in Patients with Atherosclerotic Renal Artery Stenosis by Xiang Huang, Xiao-Lan Li, Heng Zhou, Xiao-Mei Li

“…ROC analysis revealed that rQFR had a high diagnostic accuracy for predicting blood pressure improvement (AUCrQFR=0.932, 95% CI 0.798-0.998). …”
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Yaws in Africa: Past, Present and Future by Ezekiel K. Vicar, Shirley V. Simpson, Gloria I. Mensah, Kennedy K. Addo, Eric S. Donkor

“…<b>Conclusions</b>: There is a great prospect for eradication if countries capitalize on the availability of simple, inexpensive, and well-tolerated oral treatment that has proven effective, validated point-of-care diagnostic tests and new molecular tests. Countries should embark on integrated disease control efforts to increase sustainability and improve the quality of life for people living with this NTD in poor communities.…”
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Long-term cardiac MRI follow up of MANTICORE (Multidisciplinary Approach to Novel Therapies in Cardio-Oncology REsearch) by Dina Labib, Mark Haykowsky, Emer Sonnex, John R. Mackey, Richard B. Thompson, D. Ian Paterson, Edith Pituskin

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