Refining α-synuclein seed amplification assays to distinguish Parkinson’s disease from multiple system atrophy by James A. Wiseman, Clinton P. Turner, Richard L. M. Faull, Glenda M. Halliday, Birger Victor Dieriks

“…With further validation of these quantitative parameters, we propose that SAAs could advance from a yes/no diagnostic to a theranostic biomarker that could be utilised in developing therapeutics.…”
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MAEMC-NET: a hybrid self-supervised learning method for predicting the malignancy of solitary pulmonary nodules from CT images by Tianhu Zhao, Tianhu Zhao, Yong Yue, Hang Sun, Jingxu Li, Yanhua Wen, Yudong Yao, Wei Qian, Yubao Guan, Shouliang Qi, Shouliang Qi

“…This study aims to address this diagnostic challenge by developing a novel deep learning model.MethodsThis study proposes MAEMC-NET, a model integrating generative (Masked AutoEncoder) and contrastive (Momentum Contrast) self-supervised learning to learn CT image representations of intra- and inter-solitary nodules. …”
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Laparoscopic Diagnosis and Laparoscopic Hyperthermic Intraoperative Intraperitoneal Chemotherapy for Pseudomyxoma Peritonei Detected by CT Examination by Masamitsu Hirano, Yutaka Yonemura, Emel Canbay, Masumi Ichinose, Tuyoshi Togawa, Takayuki Matsuda, Nobuyuki Takao, Akiyoshi Mizumoto

“…Eleven patients were managed by diagnostic laparoscopy followed by laparoscopic HIPEC (LHIPEC). …”
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Comparison of Chest Computed Tomography (CT) Imaging Patterns and Severity among COVID-19 Patients during the First and Fourth Waves in Addis Ababa, Ethiopia by Lensa Million Baharu, Amir Alwan, Seife Teferi Dellie, Tesfaye Kebede Legesse, Kibruyisfaw Weldeab Abore

“…An institution-based cross-sectional study was conducted on 200 polymerase chain reaction test confirmed COVID-19 patients who underwent chest CT scan imaging in two diagnostic centers in Addis Ababa city. Pioneer and Wudassie diagnostic centers were selected due to the high case load and availability of well-experienced cardiothoracic radiologists. …”
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Predictive model for determining the indications for automated 3D ultrasound for screening patients at low risk of developing breast tumors by A. E. Garanina, A. V. Kholin

“…The study identified important pre-diagnostic factors for the choice of a diagnostic algorithm for breast examination in women of different age groups, and determined the indications for 3D ultrasound. …”
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Association between triglyceride-glucose index and its composite obesity indexes and cardio-renal disease: analysis of the NHANES 2013-2018 cycle by Yu Wu, Chengsen Liu, Jiandong Cao

“…Based on ROC curves, TyG-WHtR and TyG-WC emerged as more reliable diagnostic tools than TYG for cardiac and renal diseases. …”
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Insulin resistance and β-cell dysfunction in individuals with normal glucose tolerance but elevated 1-h post-load plasma glucose by Qianwen Nie, Xue Jin, Yahui Mu, Youyuan Huang, Aimei Dong

“…ObjectiveDiabetes and its complications impose a significant burden on public health, necessitating early identification and intervention, yet current prediabetes diagnostic criteria may not fully capture all high-risk individuals. …”
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Chemical Composition and Larvicidal Activity of Lavandula angustifolia Subsp. angustifolia and Lavandula dentata Spp. dentata Essential Oils against Culex pipiens Larvae, Vector of... by Fouad El-Akhal, Amal Ramzi, Abdellah Farah, Yassine Ez Zoubi, Moussa Benboubker, Khalid Taghzouti, Abdelhakim El Ouali Lalami

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Noninvasive hemodynamic assessment of type 2 diabetes mellitus using four-dimensional flow magnetic resonance imaging by Di Wu, Jiachen Ji, Yuancheng Wang, Shujun Zhang, Hong Ge, Mingzhu Fu, Yunduo Li, Shenghong Ju, Rui Li

“…The reproducibility of these measurements was assessed with Bland-Altman analysis, differences between groups were evaluated using t-tests, and their diagnostic utility for T2DM and DN was analyzed using ROC curves. …”
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Complete blood count parameters and inflammation-related biomarkers in patients with colorectal carcinoma by Koržinek Martha, Ćelap Ivana, Fabijanec Marija, Žanić Tena, Ljubičić Neven, Baršić Neven, Verbanac Donatella, Barišić Karmela, Rajković Marija Grdić

“…Moreover, Receiver Operating Characteristic (ROC) analysis revealed poor diagnostic accuracy, for all tested parameters (AUC was 0.7 or less). …”
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Assessment of hypoxia status in a rat chronic liver disease model using IVIM and T1 mapping by Wenlu Dong, Longyang Xiao, Ziwei Luo, Haiyang Yu, Lili Wang, Yuanxiang Gao, Zhiming Li

“…ObjectivesThis study was aimed to assess the diagnostic performance of intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) and T1 mapping in detecting hypoxia status of chronic liver disease using a carbon tetrachloride (CCl4)-induced rat model.Materials and methodsThe hypoxia group of chronic liver disease consisted of eight rats induced by injection of CCl4 and the control group consisted of nine rats injected with pure olive oil. …”
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Routine Head Computed Tomography for Patients in the Emergency Room with Trauma Requires Both Thick- and Thin-Slice Images by Kazuhide Maetani, Jun Namiki, Shokei Matsumoto, Katsutoshi Matsunami, Atsushi Narumi, Toshimi Tsuneyoshi, Masanobu Kishikawa

“…We investigated the diagnostic sensitivity of a head CT, where axial images were 10 mm thick slices, in cases of linear skull fractures. …”
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The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer by Yu Chen, Facai Cui, Xiaoyu Wu, Weifeng Zhao, Qingxin Xia

“…The combined detection of DLEU1, carbohydrate antigen 125 (CA-125) and squamous cell carcinoma (SCC) exhibited significantly higher diagnostic efficiency (p < .01). Furthermore, the overall survival (OS) and disease-free survival (DFS) of CC patients in the high DLEU1 expression group were markedly lower than those in the low DLEU1 expression group (both p < .01). …”
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Adiponectin and Nitric Oxide Deficiency-Induced Cognitive Impairment in Fatigued Home-Resident in Mature and Older Adults: A Case-Control Study by Ahmad H. Alghadir, Sami A. Gabr, Murad Almomani, Fidaa Almomani, Cynthia Tse

“…Moreover, the results might recommend the use of cellular adiponectin and NO as diagnostic indicators of cognitive abilities in fatigued mature and older adults. …”
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Value of transabdominal ultrasonography for diagnosing functional constipation in children: a systematic review and meta-analysis by Duc Long Tran, Phu Nguyen Trong Tran, Paweena Susantitaphong, Phichayut Phinyo, Palittiya Sintusek

“…This systematic review and meta-analysis aimed to assess the diagnostic parameters of FC including rectal diameter (RD) and anterior rectal wall thickness. …”
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Higher systemic immune-inflammation index is associated with increased risk of Parkinson’s disease in adults: a nationwide population-based study by Jiayu Zhao, Zhipeng Wu, Zhipeng Wu, Fengyin Cai, Xuejv Yu, Zhenyu Song

“…Receiver operating characteristic (ROC) curves was used to explore the diagnostic value of SII for PD.ResultsA total of 54,027 adults (mean age 35 years) were included in this study. …”
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Pathogen delivery route impacts disease severity in experimental Mycoplasma ovipneumoniae infection of domestic lambs by Bryan Tegner Jacobson, Jessica DeWit-Dibbert, LaShae Zanca, Sobha Sonar, Carol Hardy, Michael Throolin, Patricia C. Brewster, Kaitlyn Andujo, Kerri Jones, Jonathon Sago, Stephen Smith, Lizabeth Bowen, Diane Bimczok

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Significance of Combining Bronchoalveolar Lavage Fluid With Targeted Next‐Generation Sequencing in the Pathogen Detection‐Based Diagnosis of Pulmonary Infections by Jiangbo Liu, Bo Yang, Yu Wu, Guihong Yang, Xiaojiu Zha, Wei Jiang

“…Additionally, diagnostic rates obtained through tNGS were compared with mNGS between the two groups. …”
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High Body Roundness Index Is Associated With Unhealthy Sleep Patterns: Insights From NHANES (2007–2014) by Pingchuan Liu, Yuding Luo, Xing He, Jiali Zhang, Fanzhou Ren, Bingyang Zhang, Bo Zheng, Jian Wang

“…Receiver operating characteristic (ROC) analysis was used to compare the diagnostic performance of BRI and body mass index (BMI) in identifying unhealthy sleep patterns. …”
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The Utility of Repeat Endoscopic Ultrasound-Guided Fine Needle Aspiration for Suspected Pancreatic Cancer by Mark Nicaud, Wei Hou, Dennis Collins, Mihir S. Wagh, Shailendra Chauhan, Peter V. Draganov

“…The utility of repeat EUS in patients with suspicion for pancreatic cancer after non-diagnostic EUS-FNA study is not well established. Aim. …”
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