miR-208a-3p discriminates osteoporosis, predicts fracture, and regulates osteoclast activation through targeting STC1 by Hongbing Qian, Fei Jia, Huiling Qin

“…Conclusion Serum miR-208a-3p served as a diagnostic biomarker for OP and a risk factor for fracture in post-menopausal women. miR-208a-3p regulated macrophage inflammation and further mediated osteoclast activation via targeting STC1.…”
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Justification for the physiological isolation of the torus based on the pain sensitivity of the oral mucosa by Alijon Sobirov, Sunnatullo Gafforov, Nurmukhamet Ruzuddinov, Raykhon Pulatova, Ravshanbek Jambilov, Kalamkas Ruzuddinova, Zukhriddin Djumaev, Sevara Gafforova

“…Measurements of pain sensitivity and compliance of the oral mucosa were performed, and diagnostic models were studied. Patients who had partial and full removable plate prostheses made using our developed techniques noted a positive shift in the quality of life after prosthetics, in comparison with prostheses made earlier. …”
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Accuracy of Teledentistry for Diagnosis and Treatment Planning of Pediatric Patients during COVID-19 Pandemic by Ozra Golsanamloo, Sanaz Iranizadeh, Amir Reza Jamei Khosroshahi, Leila Erfanparast, Ali Vafaei, Yalda Ahmadinia, Solmaz Maleki Dizaj

“…The overall purpose of the study was to assess the diagnostic sensitivity and specificity of virtual (mobile phone teledentistry) compared with clinical examinations during COVID-19. …”
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Cytological Features of Mammary Analogue Secretory Carcinoma of the Parotid Gland in a 15-Year-Old Girl: A Case Report with Review of the Literature by Takako Inaba, Yuki Fukumura, Tsuyoshi Saito, Junkichi Yokoyama, Shinichi Ohba, Atsushi Arakawa, Takashi Yao

“…In addition to the case report, we present a review of the related literature with a focus on the cytological features of MASC. The differential diagnostic clues are also discussed.…”
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Public Understanding and Expectations of Digital Health Evidence Generation: Focus Group Study by Paulina Bondaronek, Jingfeng Li, Henry W W Potts

“…This gap has prompted ongoing debate about the types of evidence necessary to validate health apps, especially as the perceived risk level varies from wellness tools to diagnostic aids. The perspectives of the general public, who are direct stakeholders, are notably underrepresented in discussions on digital health evidence generation. …”
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SPR Biosensor Based on Bilayer MoS₂ for SARS-CoV-2 Sensing by Talia Tene, Stefano Bellucci, Cristian Vacacela Gomez

“…The findings establish the proposed biosensor as a robust and precise diagnostic tool for SARS-CoV-2 detection, with potential applications in clinical diagnostics and epidemiological monitoring.…”
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Reducing lead requirements for wearable ECG: Chest lead reconstruction with 1D-CNN and Bi-LSTM by Kazuki Hebiguchi, Hiroyoshi Togo, Akimasa Hirata

“…Wearable ECG devices encounter significant challenges in replicating the diagnostic capabilities of standard 12-lead ECGs, primarily due to the complexity of electrode placement and the need for specialized equipment. …”
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Performance of current tools used for on-the-day assessment and diagnosis of mild traumatic brain injury in sport: a systematic review by Phoebe Haste, Leonardo de Almeida e Bueno, Antoine Jérusalem, Jeroen Bergmann

“…Further exploration of the mechanisms and time-dependent pathophysiology of SR-mTBI could result in more targeted diagnostic and monitoring techniques. The Podium Institute for Sports Medicine and Technology funded this work.PROSPERO registration number CRD42022376560.…”
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Cervical Cancer Screening Program by Visual Inspection: Acceptability and Feasibility in Health Insurance Companies by Apollinaire G. Horo, Judith Didi-Kouko Coulibaly, Abdoul Koffi, Boris Tchounga, Konan Seni, Kacou Edèle Aka, Mamourou Kone

“…To assess willingness to participate and diagnostic accuracy of visual inspection for early detection of cervical neoplasia among women in a health insurance company. …”
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Comprehensive Analysis Reveals PTK6 as a Prognostic Biomarker Involved in the Immunosuppressive Microenvironment in Breast Cancer by Lili Wang, Shuimei Luo, Ziming Wang, Yiqiang Huang, Yang Luo, Xianhe Xie

“…In this study, we discovered that the expressions of PTK6 were significantly raised in the majority of different types of malignancies, including BC. The diagnostic value of PTK6 expression was validated by ROC tests, demonstrating an AUC greater than 0.7. …”
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Serum Amyloid Alpha in Parapneumonic Effusions by Vagelis Boultadakis, Vasilis Skouras, Demosthenes Makris, Aggeliki Damianaki, Dimitrios J. Nikoulis, Theodoros Kiropoulos, Smaragda Oikonomidi, Irene Tsilioni, Konstantinos Gourgoulianis

“…To assess serum amyloid alpha (SAA) pleural fluid levels in parapneumonic effusion (PPE) and to investigate SAA diagnostic performance in PPE diagnosis and outcome. …”
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Neuroborreliosis with encephalitis: a broad spectrum of clinical manifestations by Dominica Hudasch, Franz Felix Konen, Nora Möhn, Lea Grote-Levi, Ulrich Wurster, Gabriel Welte, Josef Conzen, Nima Mahmoudi, Thomas Skripuletz, Philipp Schwenkenbecher

“…Patients were only included if they met the diagnostic criteria for definite neuroborreliosis. Results A total of seven patients with neuroborreliosis induced encephalitis were identified. …”
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Comparing Sensitivity and Specificity of Addenbrooke’s Cognitive Examination-I, III and Mini-Addenbrooke’s Cognitive Examination in Parkinson’s Disease by Tivadar Lucza, Zsuzsanna Ascherman, Márton Kovács, Attila Makkos, Márk Harmat, Annamária Juhász, József Janszky, Sámuel Komoly, Norbert Kovács, Krisztina Dorn, Kázmér Karádi

“…Normal cognition, mild and major NCD were judged in accordance with the respective criteria of the Diagnostic and Statistical Manual of Mental Disorders 5th edition. …”
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Systemic Inflammatory Cytokines Predict the Infectious Complications but Not Prolonged Postoperative Ileus after Colorectal Surgery by G. S. A. Boersema, Z. Wu, A. G. Menon, G. J. Kleinrensink, J. Jeekel, J. F. Lange

“…Instead, postoperative IL-6 changes may predict the infectious complications with a better diagnostic value than the current leukocytes or CRP tests.…”
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Prevalence and Management Recommendations for Disease-Related Malnutrition in Chronic Kidney Disease Patients with and without Diabetes by Li-Li Dai, Wei-Li Li, Ding-Feng Zheng, Wei-Hong Wang, Hao-Fen Xie, Jian-Wei Ma

“…The prevalence of malnutrition was 16.7% (114/683) in the patients included in the survey using the diagnostic criteria of malnutrition (GLIM) (excluding whole body muscle mass index). …”
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The Role of Imaging in Patient Selection, Preoperative Planning, and Postoperative Monitoring in Human Upper Extremity Allotransplantation by Eira S. Roth, David G. Buck, Vijay S. Gorantla, Joseph E. Losee, Daniel E. Foust, Cynthia A. Britton

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Cavernous Hemangioma-Like Kaposi Sarcoma: Histomorphologic Features and Differential Diagnosis by Nilüfer Onak Kandemir, Figen Barut, Banu Doğan Gün, Nilgün Solak Tekin, Sevinç Hallaç Keser, Şükrü Oğuz Özdamar

“…Cavernous hemangioma-like Kaposi sarcoma is a rare Kaposi sarcoma variant presenting with diagnostic challenges, that may be confused with hemangioma. …”
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Aggressive Disease Course of Multiple Myeloma with Concomitant ALK-Negative Anaplastic Large Cell Lymphoma: A Case Report with an Unusual Presentation by Michela Staderini, Lara Mannelli, Elisabetta Antonioli, Benedetta Puccini, Valentina Berti, Francesco Mungai, Federica Vergoni, Valentina Carrai, Luigi Rigacci, Alberto Bosi

“…ALK-negative anaplastic large cell lymphoma is a rare T-cell neoplasm with an aggressive course requiring prompt diagnostic work-up and treatment. Few cases of concomitant multiple myeloma and T-cell neoplasm are described in the literature, mainly regarding primary cutaneous anaplastic large cell lymphoma. …”
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Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer? by Jia-Le Zhang, Zhen-Ning Wang, Hui-Mian Xu, Zhi Zhu, Bao-Jun Huang

“…The AUC proved that they possessed significant diagnostic value. When CT examination was negative, the combination of serum CEA and tumor size showed high specificity (95.3%; 164/172), negative predictive value (92.7%; 164/177), and accuracy (89.0%; 170/191). …”
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Unveiling Genital Tuberculosis: India’s hidden Infertility Epidemic by Yashvanthan VR, Angeline Grace G, Sujitha P, Ilam Ilaval T, Hariharan S

“…Despite its prevalence, GTB remains a hidden epidemic due to limited awareness, diagnostic challenges, and systemic healthcare gaps. …”
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