Development and Validation of a Novel ELISA for the Specific Detection of Antibodies against Mycobacterium avium Subspecies paratuberculosis Based on a Chimeric Polyprotein by Roberto Damián Moyano, Magali Andrea Romero, María Alejandra Colombatti Olivieri, María Fiorella Alvarado Pinedo, Gabriel Eduardo Traveria, María Isabel Romano, María Natalia Alonso

“…In this work, we aimed to develop and validate a diagnostic tool based on an ELISA to specifically detect anti-MAP antibodies from bovine serum samples. …”
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Induced pathomorphism and manifestations of residual focal lesions in parenchymatous organs of patients after noninvasive procedures by Z. A. Lemeshko, A. V. Borsukov, A. V. Mamoshin, T. G. Morozova

“…Ultrasound investigation was the basic diagnostic and control method; while helical x-ray computer tomography, X-ray fistulography, endoscopic retrograde cholangiopancreatography, scintigraphy, elastography, diagnostic punctures (aspiration biopsy, core needle biopsy, transcutaneous transhepatic cholangiography), laparoscopy, laparotomy, morphological investigation were used as methods of verification and control. …”
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The Efficacy of Clinical Tests to Diagnose Evaporative Dry Eye Disease Related to Meibomian Gland Dysfunction by Jerry R. Paugh, Tiffany Nguyen, Alan Sasai, Elaine Chen, Melinda Thomas De Jesus, Justin Kwan, Andrew Loc Nguyen, Marjan Farid, Sumit Garg, James V. Jester

“…In a larger, independent sample of normal and EDED subjects, gland secretion quality and eyelid marginal score achieved acceptable diagnostic levels: AUCs of 0.789 (CI: 0.734–0.844) and 0.729 (CI: 0.648–0.810), respectively, but not lipid interferometry grade or lower eyelid gland dropout estimated using meiboscopy. …”
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Periodontal Disease and Obstructive Sleep Apnea: Shared Mechanisms, Clinical Implications, and Future Research Directions by Serena Incerti Parenti, Claudio Cesari, Veronica Della Godenza, Matteo Zanarini, Francesca Zangari, Giulio Alessandri Bonetti

“…However, the causative nature of the relationship between OSA and PD remains uncertain, largely due to inconsistencies in diagnostic criteria, methodological variability, and study heterogeneity. …”
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A study on Bacterial Infections Associated with Central Nervous System in Pakistani Population by Muneeba Afzal, Hamza Altaf, Tayyaba Faiz, Samra Mannan

“… Objective: This paper reviews the evolving trends and epidemiology of CNS infections in Pakistan over four decades, exploring pathophysiology, diagnostic criteria, and treatment approaches through systematic review and meta-analysis. …”
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Development and external validation of machine learning-based models to predict patients with cellulitis developing sepsis during hospitalisation by Li Hu, Xilingyuan Chen, Rentao Yu

“…The performances and robustness of selected models were further compared in the external-validation group by area under the curve (AUC), diagnostic accuracy, sensitivity, specificity and diagnostic OR.Primary outcome measures The primary outcome of interest in this study was the development based on the Sepsis-3.0 criteria during hospitalisation.Results Patient characteristics were significantly different between the two groups. …”
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Indications and Relative Utility of Lower Endoscopy in the Management of Clostridium difficile Infection by Nora E. Burkart, Mary R. Kwaan, Christopher Shepela, Robert D. Madoff, Yan Wang, David A. Rothenberger, Genevieve B. Melton

“…Diagnosis and management of Clostridium difficile infection (CDI) rely upon clinical assessments and diagnostic studies. Among diagnostic tests, lower gastrointestinal (GI) endoscopy in the setting of CDI remains controversial. …”
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THE USE OF ARTIFICIAL INTELLIGENCE ON COLPOSCOPY IMAGES AND SEGMENTAL VOLUMES, CONSTRUCTED FROM MRI AND CT IMAGES, IN THE DIAGNOSIS AND STAGING OF PRECANCERS, CERVICAL CANCERS AND... by Hlescu Cristian Stefan, Tudor Florin Ursuleanu, Roxana Grigorovici, Andreea Roxana Luca, Ramona Elena Teiu, Maria Paula Comanescu, Alina Ionela Calin, Alexandru Grigorovici

“…Aim of the study For the accurate diagnosis and staging of precancers and cervical and thyroid cancer, we aim to create a diagnostic method optimized by artificial intelligence (AI) algorithms and validated by the notable positive results of a randomized, controlled, 17-month trial.. …”
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Correlation between Fine-Needle Aspiration Cytology and Histology for Palpable Breast Masses in a Nigerian Tertiary Health Institution by Adetola Olubunmi Daramola, Mosebolatan Olatokunboh Odubanjo, Fred John Obiajulu, Nzechukwu Zimudo Ikeri, Adekunbiola Aina Fehintola Banjo

“…Objective. To determine the diagnostic accuracy of FNAC of palpable breast lesions within a 5-year period. …”
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Staging of esophageal cancer using PET/MRI: a systematic review with head-to-head comparison by Alisa Mohebbi, Saeed Mohammadzadeh, Zahra Moradi, Afshin Mohammadi, Hossein Poustchi, Seyed Mohammad Tavangar

“…The risk of bias was assessed using Modified Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) and Quality Assessment of Diagnostic Accuracy Studies–Comparative (QUADAS-C). …”
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Internally Controlled, Generic Real-Time PCR for Quantification and Multiplex Real-Time PCR with Serotype-Specific Probes for Serotyping of Dengue Virus Infections by Sandra Menting, Khoa T. D. Thai, Tran T. T. Nga, Hoang L. Phuong, Paul Klatser, Katja C. Wolthers, Tran Q. Binh, Peter J. de Vries, Marcel Beld

“…Dengue has become a global public health problem and a sensitive diagnostic test for early phase detection can be life saving. …”
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Assessment of Bone Mineral Density in Male Patients with Chronic Obstructive Pulmonary Disease by DXA and Quantitative Computed Tomography by George Fountoulis, Theodora Kerenidi, Constantinos Kokkinis, Panagiotis Georgoulias, Paschal Thriskos, Konstantinos Gourgoulianis, Ioannis Fezoulidis, Katerina Vassiou, Marianna Vlychou

“…QCT measurements have an improved discriminating ability to identify low BMD compared to DXA measurements because QCT is able to overcome diagnostic pitfalls including aortic calcifications and degenerative spinal osteophytes.…”
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Consultation diagnoses and procedures billed among recent graduates practicing general otolaryngology – head & neck surgery in Ontario, Canada by Antoine Eskander, Paolo Campisi, Ian J. Witterick, David D. Pothier

“…Methods Ontario billing data were used to identify the most common diagnostic and procedure codes used by general otolaryngologists issued a billing number between 2006 and 2012. …”
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Hematological parameters in pediatric pulmonary and extrapulmonary tuberculosis in Vietnam: a prospective observational study by Chau Duc Nguyen-Huu, Thi Hanh Chan Tran, Thi Hong Nhung La, Van-Tuy Nguyen

“…The SII index had the best diagnostic value with an AUC of 0.832, sensitivity of 66.7%, and specificity of 86.7%. …”
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Validation of the German Glasgow Sensory Questionnaire in autistic adults by Isabel Marie Jakob, Veit Roessner, Melanie Ring

“…It can be used to assess sensory sensitivity in the diagnostic process of autism spectrum disorder and to assess an individual's sensory needs and strengths for best possible support. …”
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Identifcation of genotypescarriers of resistance to tan spot Ptr ToxA and Ptr ToxB of Pyrenophora tritici-repentis in common wheat collection by A. М. Kokhmetova, Sh. Ali, Z. Sapakhova, M. N. Atishova

“…This demonstrates the reliability of the diagnostic marker Xfcp623 for identifying wheat genotypes with resistance to the fungus and insensitivity to Ptr ToxA. …”
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The Temporal Pattern of Arterial Stiffness during Aging: A Large-Scale Cross-Sectional Study by Zhengli Tang, Yuanyuan Lu, Yiming Hao, Robert Morris, Di Kang, Fang Wang, Lin Fan, Weijian Wang, Yiqin Wang, Feng Cheng

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The Unforeseen Diagnosis: Hyperparathyroidism-Jaw Tumour Syndrome Case Report and Review of the Literature by Maxim Barnett, Farhan Ahmed, Radu Mihai, Asha Rattan, Malik Asif Humayun

“…Medical professionals must avoid diagnostic overshadowing and display a low threshold for genetic testing in younger patients with primary hyperparathyroidism. …”
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Comparison of Liver Biopsy Findings with the Digestive Disease Week Japan 2004 Scale for Diagnosis of Drug-Induced Liver Injury by Akemi Tsutsui, Yasuni Nakanuma, Kouichi Takaguchi, Satoko Nakamura, Hiroshi Shibata, Nobuyuki Baba, Tomonori Senoh, Takuya Nagano, Hiroko Ikeda

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An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Settin... by Mohsen Khosravi, Domenico De Berardis, Sahel Sarabandi, Sakineh Mazloom, Amir Adibi, Negin Javan, Zahra Ghiasi, Mohammad Nafeli, Negar Rahmanian

“…Hence, identifying reliable and innovative diagnostic alternatives seems crucial. Accordingly, a summary of gathered evidence is provided by the present review for enhancing future evaluation of oropharyngeal microbiome composition as a practical indicator for diagnosing true psychosis in a forensic psychiatric setting. …”
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