A telehealth-delivered intervention to extend the veteran HIV treatment cascade for cardiovascular disease prevention: V-EXTRA-CVD study protocol for a randomized controlled trial by Lewis Musoke, Hayden B. Bosworth, Christina Dickson, Pamela Gentry, Elizabeth Strawbridge, Soumya Subramaniam, Jennifer Gierisch, Valerie Smith, Sandra Woolson, John Pura, Willington Amutuhaire, Susanna Naggie, Julie Schexnayder, Karen Hall, Chris T. Longenecker, Nadine M. Harris, Chantrice Rogers, Puja Van Epps, for V-EXTRA-CVD Group

“…We aim to conduct a randomized control trial among PWH (n = 300) with a diagnosis of hypertension (HTN) who are enrolled in Veterans Health Administration (VHA) clinics, on suppressive antiretroviral therapy (ART), randomized 1:1 to intervention vs. education control for a 12-month duration. …”
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Similar Clinical and Surgical Outcomes Achieved with Early Compared to Late Anti-TNF Induction in Mild-to-Moderate Ulcerative Colitis: A Retrospective Cohort Study by Christopher Ma, Candace L. Beilman, Vivian W. Huang, Darryl K. Fedorak, Karen Wong, Karen I. Kroeker, Levinus A. Dieleman, Brendan P. Halloran, Richard N. Fedorak

“…Patients were stratified by time to first anti-TNF exposure; early initiation was defined as starting treatment within three years of diagnosis. Primary outcomes were colectomy, UC-related hospitalization, and clinical secondary loss of response. …”
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Screening of West Siberian patients with primary congenital glaucoma for CYP1B1 gene mutations by D. E. Ivanoshchuk, S. V. Mikhailova, O. G. Fenkova, E. V. Shakhtshneider, A. Z. Fursova, I. V. Bychkov, M. I. Voevoda

“…Consequently, in children with signs of increased intraocular pressure, molecular genetic analysis of the CYP1B1 gene is advisable for early diagnosis and timely initiation of PCG therapy.…”
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Congenital Zika Syndrome: Insights from Integrated Proteomic and Metabolomic Analysis by Leticia Gomes-de-Pontes, Lucila Akune Barreiros, Lillian Nunes Gomes, Ranieri Coelho Salgado, Sarah Maria da Silva Napoleão, Paulo V. Soeiro-Pereira, Saulo Duarte Passos, Antonio Condino-Neto

“…Additionally, the results identified potential biomarkers capable of aiding early diagnosis and assessing disease progression. <b>Conclusions:</b> This study demonstrates that EVs play a crucial role in intercellular communication during Zika virus infection. …”
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TG : HDL-C Ratio Is a Good Marker to Identify Children Affected by Obesity with Increased Cardiometabolic Risk and Insulin Resistance by Ahmad Kamil Nur Zati Iwani, Muhammad Yazid Jalaludin, Ruziana Mona Wan Mohd Zin, Md Zain Fuziah, Janet Yeow Hua Hong, Yahya Abqariyah, Abdul Halim Mokhtar, Wan Nazaimoon Wan Mohamud

“…TG : HDL-C ratio in children with obesity is thus as useful as the diagnosis of MetS. It should be considered an additional component to MetS, especially as a surrogate marker for IR.…”
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Socioeconomic status and delayed surgery: impact on non-metastatic papillary thyroid carcinoma outcomes by Kun Zhang, Xinyi Wang, Jianyong Lei, Anping Su, Tao Wei, Zhihui Li, Ya-Wen Chen, Ya-Wen Chen, Ya-Wen Chen, Ya-Wen Chen, Ya-Wen Chen

“…Kaplan–Meier survival curve, Cox proportional hazard regression, competing risk hazard regression, and multinomial logistic regression were applied.ResultsReceiving neck dissection or radioactive iodine therapy, being married at diagnosis, living in an urban area, being richer, and being of other minority ethnicity were estimated to be independent predictors for better overall survival. …”
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Stress and Interpersonal Relationships in Medical Students During Public Health Emergencies: A Network Analysis by Cui Y, Guo Z, Yang T, Zhang M, Mu H, Li J, Fang J, Du T, Yang X

“…The mental health of medical students plays a vital role in their training, and interpersonal relationships are an important factor affecting their stress levels.Purpose: This study aims to investigate the network structure of stress and interpersonal relationships among Chinese medical students and identify bridge variables to prevent and relieve this stress.Patients and Methods: A self-report measurement taken from the Sociodemographic Questionnaire, Stress Scale for College Students and Interpersonal Relationship Synthetic Diagnosis Test was administered to 322 Chinese medical students from January to April 2022. …”
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p54-Fc-Labeled Gold Nanoparticle-Based Lateral Flow Strip-Assisted Portable Devices for Rapid and Quantitative Point-of-Care Detection of ASFV Antibodies by Yang Yang, Yuhao Li, Ziyang Wang, Minglong Tong, Pengcheng Zhu, Juanxian Deng, Zongjie Li, Ke Liu, Beibei Li, Donghua Shao, Zhongren Zhou, Yafeng Qiu, Zhiyong Ma, Jianchao Wei

“…This approach saves time for antibody preparation, resulting in a shorter production cycle. p54 is an important structural protein of African swine fever, and an ideal protein for serotype diagnosis. Gold nanoparticles are attached to the ASFV p54-Fc fusion protein, and the ASFV-specific antigen p54 and Staphylococcus aureus protein A (SPA) are labeled on a nitrocellulose membrane, at positions T and C, respectively. …”
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Primary Terminal Haemochromatosis in a 50 Year-Old Patient by M. I. Gonik, M. S. Zharkova, O. Yu. Kiseleva, E. V. Berezina, Sh. A. Ondos, Yu. V. Lerner, E. A. Kogan, V. T. Ivashkin

“…Genotyping revealed the HFE 845G &gt; A variant diagnostic of haemochromatosis type 1. Clinical diagnosis: Primary disease: haemochromatosis (homozygous variant HFE 845G &gt; A (A/A)): liver cirrhosis, Child-Pugh class C. …”
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Genetic Biomarkers and Circulating White Blood Cells in Osteoarthritis: A Bioinformatics and Mendelian Randomization Analysis by Yimin Pan, Xiaoshun Sun, Jun Tan, Chao Deng, Changwu Wu, Georg Osterhoff, Nikolas Schopow

“…The pathogenesis of OA remains poorly understood, creating an urgent need for biomarkers to aid research, diagnosis, and treatment. <b>Methods</b>: This study integrated transcriptome data from the GEO database with bioinformatics analyses to identify biomarkers associated with OA. …”
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Clinical Value of Renal Function Markers Combined with Blood Lipid Levels during Late Pregnancy to Predict Preeclampsia: A Retrospective Case-Control Study by Jindi Zhang, Pei Wang, Jie Liu

“…And their combination has a certain predictive value for PE, which may offer a fresh, convenient and efficient method for the diagnosis and treatment of PE.…”
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Increased Mortality After Lower Extremity Amputation in a Danish Nationwide Cohort: The Mediating Role of Postoperative Complications by Brix ATH, Petersen TG, Nymark T, Schmal H, Lindberg-Larsen M, Rubin KH

“…Mediators were identified through diagnosis codes (ICD-10) present in 6 months following MLEA.Results: The increased mortality following MLEA was highest in the month following MLEA, hazard ratio (HR) 38.7 (95% confidence interval (CI) 30.5– 48.9) in women and HR 55.7 (CI 44.3– 70.2) in men compared to a matched unamputated cohort. …”
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A User-Centered Design Approach for a Screening App for People With Cognitive Impairment (digiDEM-SCREEN): Development and Usability Study by Michael Zeiler, Nikolas Dietzel, Fabian Haug, Julian Haug, Klaus Kammerer, Rüdiger Pryss, Peter Heuschmann, Elmar Graessel, Peter L Kolominsky-Rabas, Hans-Ulrich Prokosch

“…Digital screening instruments are one way to increase diagnosis rates. Developing an app for older adults presents several challenges, both technical and social. …”
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Elevated resting heart rate in adolescent men and risk of heart failure and cardiomyopathy by Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria Åberg, Kjell Torén, Margda Waern, N. David Åberg, Annika Rosengren

“…The corresponding HR was 1.43 (CI = 1.08–1.90) for HF associated with CM and 1.34 (CI = 1.16–1.54) for HF without concomitant diagnosis. There was an association between RHR and dilated CM [HR = 1.47 (CI = 1.27–1.71)] but not hypertrophic, alcohol/drug‐induced, or other cardiomyopathies. …”
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A systematic review and meta-analysis: prevalence and clinical implications of anatomical variants of the hepatic portal vein by Juan José Valenzuela-Fuenzalida, Benjamín Rodríguez-Osorio, Cristian Salgado-Torres, Pablo Nova-Baeza, Mathias Orellana-Donoso, Alejandro Bruna-Mejías, Roberto Avila-Sepulveda, Álvaro Becerra-Farfán, Macarena Rodríguez-Luengo, Juan Sanchis-Gimeno, Guinevere Granite, Héctor Gutiérrez-Espinoza

“…The knowledge of HPV and its anatomical variants is of utmost importance for both medical professionals and anatomists, as it is one of the vessels that collects blood from many important viscera found in the abdominal cavity, any structural alteration could be crucial in diagnosis and surgical procedures.…”
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The economic burden of breast cancer in western Iran: a cross-sectional cost-of-illness study by Banafsheh Darvishi Teli, Meysam Behzadifar, Mania Beiranvand, Aziz Rezapour, Seyed Jafar Ehsanzadeh, Samad Azari, Ahad Bakhtiari, Payam Haghighatfard, Mariano Martini, Maryam Saran, Masoud Behzadifar

“…Early detection and prevention programs can facilitate earlier diagnosis and reduce treatment costs. Comprehensive policies addressing both medical and non-medical expenses are necessary to improve patients’ quality of life and lessen the financial challenges associated with breast cancer in Iran.…”
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Meckel’s Diverticulum Diagnosed by Balloon-Assisted Enteroscopy: A Multicenter Report from the Taiwan Association for the Study of Small Intestinal Diseases (TASSID) by Jen-Wei Chou, Chen-Shuan Chung, Tien-Yu Huang, Chia-Hung Tu, Chen-Wang Chang, Chung-Hsin Chang, Yen-Po Wang, Wen-Hung Hsu, Hsu-Heng Yen, Chia-Jung Kuo, Chiao-Hsiung Chuang, Ching-Pin Lin, Tzung-Jiun Tsai, Ming-Yao Su, Horng-Yuan Wang, Deng-Chyang Wu, Cheng-Tang Chiu

“…A total of 55 patients with MD were enrolled (46 males and 9 females). The mean age at diagnosis was 34.1 years. Overt gastrointestinal bleeding (87.3%) was the primary indication for BAE, followed by abdominal pain (9.1%), suspected small bowel tumor (1.8%), and Crohn’s disease follow-up (1.8%). …”
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Comparative Analysis of Immunoactivation by Nanosecond Pulsed Electric Fields and PD-1 Blockade in Murine Hepatocellular Carcinoma by Maiweilidan Yimingjiang, Talaiti Tuergan, Xinhua Chen, Hao Wen, Yingmei Shao, RuiQing Zhang, Kasimu Aihaiti, Jing Xue, Tuerganaili Aji, Wei Zhang

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Global seroprevalence of Toxoplasma gondii in pregnant women: a systematic review and meta-analysis by Nader Salari, Avijeh Rahimi, Hosna Zarei, Amir Abdolmaleki, Shabnam Rasoulpoor, Shamarina Shohaimi, Masoud Mohammadi

“…Thus, public awareness, along with comprehensive health programs regarding the detrimental effects of toxoplasmosis in pregnant women, seems necessary for prevention or even early diagnosis of toxoplasmosis in pregnant women.…”
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Decidualized ovarian and rectouterine deep endometriosis disguised as malignancy in the second-trimester of pregnancy: A case report by Lingjie Bao, Ting Wang, Yinping Xiao, Shouxin Gu, Xiaoyu Zhou, Yunxi Zheng, Yun Chen, Xiaofang Yi

“…A mature multidisciplinary team shows essential importance during treatment decisions. Early diagnosis of endometriosis before pregnancy help identify malignancy and reduce potential risks of maternal and fetal complications.…”
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