The availability of drugs for stable COPD treatment in China: a cross-sectional survey by Dongru Du, Xueru Hu, Qiunan Zuo, Dan Xu, Tao Zhu, Tao Fan, Jiao Yang, Weiguo Xu, Hailong Wei, Kangzhuo Baima, Ying Zhang, Yanhui Gu, Lei Chen, Fengming Luo, Yongchun Shen, Fuqiang Wen

“…A well-constructed questionnaire was designed according to the Chinese Guidelines for the Diagnosis and Management of COPD (revised version 2021). …”
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Evaluation of Left Atrial Function in Patients with Paroxysmal Atrial Fibrillation Using Left Atrial Automatic Myocardial Functional Imaging Ultrasonography by Hailan Liu, Lili Chen, Yan Song, Yingying Xu, Chunquan Zhang

“…The ROC curve results showed that LAEF had a high efficiency in the diagnosis of NVPAF, with P < 0.001, AUC of 0.843, sensitivity of 0.788, and specificity of 0.867. …”
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Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…However, data on endoscopic treatment of CP in children are still limited.MethodsDemographics, etiology, surgical indications, diagnosis, treatment details, associated complications, and follow-up information were retrospectively studied in consecutive patients (&lt;18 years old) who underwent ERP for CP between January 2020 and October 2024.ResultsA total of 17 children (7 male, 10 female) with a mean age of 10.0 ± 2.7 years were included in the study. …”
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Segmentation of Laser Marks of Diabetic Retinopathy in the Fundus Photographs Using Lightweight U-Net by Yukang Jiang, Jianying Pan, Ming Yuan, Yanhe Shen, Jin Zhu, Yishen Wang, Yewei Li, Ke Zhang, Qingyun Yu, Huirui Xie, Huiting Li, Xueqin Wang, Yan Luo

“…With accurate segmentation and high numeric metrics, the lightweight U-Net method showed its reliable performance in automatically segmenting laser marks in fundus photographs, which could help the AI assist the diagnosis of DR in the severe stage.…”
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Sandpiper Optimization Algorithm With Region Growing Based Robust Retinal Blood Vessel Segmentation Approach by Ibrahim AlMohimeed, Mohamed Yacin Sikkandar, A. Mohanarathinam, Velmurugan Subbiah Parvathy, Mohamad Khairi Ishak, Faten Khalid Karim, Samih M. Mostafa

“…Retinal blood vessel examination is commonly utilized for retinal disease diagnosis by ophthalmologists. The automated retinal vessel segmentation process becomes an essential tool to identify disease. …”
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Microbial Colonization and Antibiotic Resistance Profiles in Chronic Wounds: A Comparative Study of Hidradenitis Suppurativa and Venous Ulcers by Florica Sandru, Elena Poenaru, Smaranda Stoleru, Andreea-Maria Radu, Alexandra-Maria Roman, Corina Ionescu, Aurelian Zugravu, Jafal Mugurel Nader, Livia-Cristiana Băicoianu-Nițescu

“…<b>Methods</b>: We conducted a cross-sectional analysis that included a total of 112 individuals (24 with the diagnosis of hidradenitis suppurativa and 88 diagnosed with venous ulcer). …”
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Internal Facilitation by Health Assistants for the &ldquo;WHO Lay Health Worker Dementia Care&rdquo; in Rural Uganda: A Formative Evaluation by Wakida EK, Obua C, Rukundo GZ, Samantha M, Maling S, Karungi CK, Talib ZM, Haberer J, Bartels SJ

“…Edith K Wakida,1,2 Celestino Obua,2 Godfrey Zari Rukundo,3 Mary Samantha,2 Samuel Maling,4 Christine K Karungi,2 Zohray M Talib,1 Jessica Haberer,5,6 Stephen J Bartels5,6 1Department of Medical Education, California University of Science and Medicine, Colton, California, USA; 2Department of Research and Development, Alpha Center for Research Administration, Mbarara, Uganda; 3Department of Psychiatry and Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada; 4Department of Psychiatry, Mbarara University of Science and Technology, Mbarara, Uganda; 5Department of Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; 6Harvard Medical School, Harvard University, Boston, Massachusetts, USACorrespondence: Edith K Wakida, Email Edith.Wakida@cusm.eduBackground: Dementia is characterized by cognitive symptoms like memory loss, difficulty with language, and impaired judgment, alongside behavioral and psychological symptoms such as depression, anxiety, and aggression. Early diagnosis and tailored care are essential for managing these symptoms, improving quality of life, and reducing caregiver burden. …”
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The Effects of MicroRNAs on Cardiomyopathy in a Rat Model of Streptozotocin-induced Diabetes Mellitus by Aslıhan Şeyda DOĞAN, Mukaddes PALA, Şenay GÖRÜCÜ YILMAZ, Ayfer BECEREN, Aydın KARABULUT, Yalçın POLAT, Hatice Kübra ELÇİOĞLU

“…In our study, the potential of miRNAs as a biomarker in the diagnosis and treatment of DCM was evaluated in the diabetes model induced by streptozotocin in rats. …”
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sB7H3 in Children with Acute Appendicitis: Its Diagnostic Value and Association with Histological Findings by Xiaochen Du, Yan Chen, Jie Zhu, Zhenjiang Bai, Jun Hua, Ying Li, Haitao Lv, Guangbo Zhang

“…Several efforts have been made to find out a valuable marker to assist the diagnosis and differentiation of gangrenous/perforated appendicitis. …”
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Prevalence of sexually transmitted infections and associated factors among male prisoners in Great Tehran Prison by active case finding by Behnam Farhoudi, Elnaz Shahmohamadi, Seyedahmad Seyedalinaghi, SeyedAlireza Nadji, Fatemeh Pahlaviani, Mehrzad Tashakorian

“…They were examined by complete genital and anal examination, followed by molecular testing for a definite diagnosis. The mean age of participants was 33.4 years. …”
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Economic evaluation of a randomized controlled trial comparing mifepristone and misoprostol with misoprostol alone in the treatment of early pregnancy loss. by Charlotte C Hamel, Marcus P L M Snijders, Sjors F P J Coppus, Frank P H A Vandenbussche, Didi D M Braat, Eddy M M Adang

“…We included 351 women with a diagnosis of EPL between 6 and 14 weeks gestation after at least one week of unsuccessful expectant management. …”
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Screening of COPD patients using the COPD diagnostic questionnaire and a portable spirometer in primary healthcare institutions: a cross-sectional, diagnostic study by Feng Chen, Qingrong Nie, Xuefeng Han, Chunjuan Li, Qimeng Liu, Feifei Xu, Li Zhang, Le Qiao, Maoxin Li, Ying Zhang, Haiyan Wang

“…The area under the ROC curve for the combined diagnosis of COPD was 0.994 (95% CI: 0.983–0.999), with a Jordan index of 0.765. …”
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Antidepressant Effects of Probucol on Early-Symptomatic YAC128 Transgenic Mice for Huntington’s Disease by Cristine de Paula Nascimento-Castro, Ana Claudia Wink, Victor Silva da Fônseca, Claudia Daniele Bianco, Elisa C. Winkelmann-Duarte, Marcelo Farina, Ana Lúcia S. Rodrigues, Joana Gil-Mohapel, Andreza Fabro de Bem, Patricia S. Brocardo

“…Depression is one of the most common psychiatric disturbances in HD, present even before manifestation of motor symptoms. Diagnosis and treatment of depression in HD-affected individuals are essential aspects of clinical management in this population, especially owing to the high risk of suicide. …”
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Predictors of failure of DISE-directed adenotonsillectomy in children with sleep disordered breathing by Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major, Hamdy El-Hakim

“…On bivariate analysis, neuropsychiatric diagnosis (r = 0.286, p = 0.042), history of sleepwalking or enuresis (r = 0.103, p = 0.044), MOS (r = 0.123, p = 0.033), presence of DNS (r = 0.107, p = 0.036), and presence of laryngomalacia (r = 0.122, p = 0.017) all positively correlated with treatment failure. …”
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Patient characteristics and predictors of mortality among children hospitalised with tuberculosis: A six-year case series study in Uganda. by Pauline Mary Amuge, Greta Lassance Becker, Rogers Nelson Ssebunya, Esther Nalumansi, Alex Adaku, Michael Juma, Jay Brooks Jackson, Adeodata Rukyarekere Kekitiinwa, Peter James Elyanu, Eric Wobudeya, Robert Blount

“…The high in-hospital mortality and long hospital stay may be reduced by timely TB diagnosis and treatment initiation among children.…”
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Racial differences in takotsubo cardiomyopathy outcomes in a large nationwide sample by Raja Zaghlol, Amit K. Dey, Sameer Desale, Ana Barac

“…Patients with a primary diagnosis of acute coronary syndrome were excluded to reduce selection bias. …”
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A Review on the Nomenclature and Taxonomy of the Old World Thread-Legged Bug Genus <i>Pleias</i> (Hemiptera: Reduviidae: Emesinae) by Zhuo Chen, Hu Li, Wanzhi Cai

“…The bibliographies, diagnosis, and known distribution records are presented for all described species, and three new species [<i>P. fashengi</i><b>sp. n.…”
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Bringing lab to the field: Exploring innovations in point-of-care diagnostics for the rapid detection and management of tropical diseases in resource-limited settings by Abdullahi Tunde Aborode, Ridwan Olamilekan Adesola, Godfred Yawson Scott, Emele Arthur-Hayford, Oche Joseph Otorkpa, Somuah Daniel Kwaku, Emmanuel Ebuka Elebesunu, Eghaghe Osadebamwen Nibokun, Ibude Jane Aruorivwooghene, Adetolase A. Bakre, Oluwaseun Adeolu Ogundijo, Olamilekan Gabriel Banwo, Oluwatobiloba Ige, Ibrahim O. Adelakun, Isreal Ayobami Onifade, Segun E. Ogungbemi, Boluwatife T. Dosunmu, Oluwaseunayo Deborah Ayando, Nike Idowu, Grace A. Adegoye, Olusegun Oluwaseun Jimoh

“…These advancements aim to provide faster diagnosis, better medical care, and ongoing monitoring in areas where traditional diagnostic methods are not practical, combining the precision of laboratory testing with the accessibility of field-based solutions. …”
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Increased Nuclear Transporter KPNA2 Contributes to Tumor Immune Evasion by Enhancing PD-L1 Expression in PDAC by Kai-Xia Zhou, Shan Huang, Li-Peng Hu, Xue-Li Zhang, Wei-Ting Qin, Yan-Li Zhang, Lin-Li Yao, Yanqiu Yu, Yao-Qi Zhou, Lei Zhu, Jianguang Ji, Zhi-Gang Zhang

“…Collectively, our data suggested that KPNA2 has the potential to serve as a promising biomarker for diagnosis in PDAC.…”
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Clinical Aspects and Prognosis Evaluation of Cirrhotic Patients Hospitalized with Acute Kidney Injury by Célio Geraldo de Oliveira Gomes, Marcus Vinicius Melo de Andrade, Ludmila Resende Guedes, Henrique Carvalho Rocha, Roberto Gardone Guimarães, Fernando Antônio Castro Carvalho, Eduardo Garcia Vilela

“…Clinical and laboratory data was collected at diagnosis between 2011 and 2015. Results. Average age was 54.6 (±10.7) years and 69.2% were male. …”
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