To Develop Biomarkers for Diabetic Nephropathy Based on Genes Related to Fibrosis and Propionate Metabolism and Their Functional Validation by Sha Li, Jingshan Chen, Wenjing Zhou, Yonglan Liu, Di Zhang, Qian Yang, Yuerong Feng, Chunli Cha, Li Li, Guoyong He, Jun Li

“…Via bioinformatic analyses, the risk of fibrosis and propionate metabolism-related biomarkers in DN were explored, thereby providing novel ideas for research related to DN diagnosis and treatment.…”
Get full text

Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis by Xavier Benarous, Hélène Lahaye, Angèle Consoli, David Cohen, Réal Labelle, Jean-Marc Guilé

“…The differences in the identification strategy of DMDD were associated with significant heterogeneity between studies in the community-based samples, with a prevalence of 0.82% (95% CI, 0.11–2.13) when all diagnosis criteria were considered. Anxiety, depressive disorders, and ADHD were the most frequent comorbidity present with DMDD. …”
Get full text

Chronic Myeloid Leukemia: Part I—Real-World Treatment Patterns, Healthcare Resource Utilization, and Associated Costs in Later Lines of Therapy in the United States by Ehab L. Atallah, Rodrigo Maegawa, Dominick Latremouille-Viau, Carmine Rossi, Annie Guérin, Eric Q. Wu, Pallavi Patwardhan

“…Treatment patterns were observed from CML diagnosis. HRU and direct healthcare costs (payer’s perspective, 2019 USD) were measured in a 3L+ setting. …”
Get full text

Lenalidomide and Dexamethasone for a Patient of POEMS Syndrome Presenting with Massive Ascites by Shuji Ueda, Sayoko Yonemoto, Kazumasa Oka, Naohiko Fujii, Keiichi Nakata, Hitomi Matsunaga, Seiko Kataoka, Yuki Iwama, Hiroyuki Narahara, Yuichi Yasunaga, Yoshiaki Inui, Sumio Kawata

“…A 57-year-old Japanese man was admitted to our hospital with pleural effusion, massive ascites, and leg edema. The diagnosis of POEMS syndrome was made based on the combination of the following findings: peripheral neuropathy, organomegaly, endocrinopathy, serum monoclonal protein elevation, skin changes, plasma VEGF elevation, and evidence of extravascular volume overload. …”
Get full text

Inter-individual Variability in Psychological Outcomes of Supervised Exercise in Adults with Type 2 Diabetes / Variabilidad interindividual en los efectos psicológicos del ejercici... by Marco Guicciardi, Romina Lecis, Davide Massidda, Lucina Corgiolu, Adelina Porru, Matteo Pusceddu, Francesca Spanu

“… Abstract: Exercise is a key component in the management of Type 2 Diabetes Mellitus (T2DM), however despite the strong evidence of its protective effects, a majority of the population with this diagnosis remains inactive and those who start an exercise program are not willing to train themselves over the long-term. …”
Get full text

Disposable and flexible smart electronic tapes for long-term biopotential monitoring by Jiuwei Gao, Mingwei Hu, Hao Sun, Yuanyuan Wang, Yuan Wei, Weiwei Li, Lu Zheng, Manzhang Xu, Qianbo Lu, Zhiyuan Liu, Hui Yang, Yongtian Wang, Weitao Song, Xuewen Wang, Wei Huang

Get full text

Kindlin-1 promotes gastric cancer cell motility through the Wnt/β-catenin signaling pathway by Jun-Ho Jang, Jiyoon Jung, Hyeon-Gu Kang, Woong Kim, Won-Jin Kim, Hana Lee, Ju Yeon Cho, Ran Hong, Jeong Won Kim, Joon-Yong Chung, Kyung-Hee Chun, Seok-Jun Kim

“…Abstract Despite advances in gastric cancer diagnosis and treatment, its prognosis remains poor owing to aggressive tumor progression and metastasis. …”
Get full text

Seasonal trends of pyogenic spondylodiscitis in Japan: a nationwide inpatient database study by Takayuki Motoyoshi, Takahisa Ogawa, Kazuyuki Fukushima, Satoshi Kutsuna, Haggai Schermann, Kiyohide Fushimi, Toshitaka Yoshii

“…Methods: We performed a retrospective nationwide study using data from the Japanese Diagnosis Procedure Combination (DPC) inpatient database, covering the period from 2010 to 2022. …”
Get full text

The extent of intestinal involvement is closely related to the severity of IgAV: a risk stratification study based on CT by Yuanqiu Li, Ziman Xiong, Yufan Wang, Yuchen Jiang, Yaqi Shen, Xuemei Hu, Daoyu Hu, Zhen Li

“…Objectives To analyze the differences in clinical manifestations between children and adults with intestinal involvement in IgAV and to identify the specific subtypes requiring particular attention.Methods A systematic review of the HIS system was conducted on patient data from four centers at Tongji Hospital between January 2015 and October 2022. Patients with a diagnosis of IgAV with intestinal involvement were further analyzed. …”
Get full text

Proteomic, metabolomic and lipidomic profiles in community acquired pneumonia for differentiating viral and bacterial infections by Samuel Rischke, Robert Gurke, Ann-Sophie Zielbauer, Nicole Ziegler, Lisa Hahnefeld, Michaela Köhm, Aimo Kannt, Maria JGT Vehreschild, Gerd Geisslinger, Gernot Rohde, Carla Bellinghausen, Frank Behrens, CAPNETZ Study group

“…These findings hold promise for facilitating the differential diagnosis of viral and bacterial pulmonary infections based on the systemic lipidome, metabolome and proteome, enabling timely treatment decisions. …”
Get full text

Problem of pain in the USA: evaluating the generalisability of high-impact chronic pain models over time using National Health Interview Survey (NHIS) data by Sean Mackey, Titilola Falasinnu, Md Belal Hossain, Mohammad Ehsanul Karim, Kenneth Arnold Weber

“…Initial models (2016 NHIS data) identified correlates associated with HICP, including hospital stays, diagnosis of specific diseases, psychological symptoms and employment status. …”
Get full text

An Unusual Case of Ototoxicity with Use of Oral Vancomycin by Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh

“…Clostridium difficile infection was confirmed by PCR, and at the time of diagnosis and initiation of therapy, the patient had normal renal function. …”
Get full text

Cardiovascular risk and mortality in men receiving testosterone replacement therapy for Klinefelter syndrome in Denmark: a retrospective cohort studyResearch in context by Simon Chang, Lars Pedersen, Anne Skakkebæk, Agnethe Berglund, Claus H. Gravholt

“…There is a dire need for a policy change to ensure timely diagnosis and treatment in all men with KS. Funding: The A.P. …”
Get full text

Delirium at the intensive care unit and long-term survival: a retrospective study by Ignazio De Trizio, Maria Angeliki Komninou, Jutta Ernst, Reto Schüpbach, Jan Bartussek, Giovanna Brandi

“…ICU-delirium was defined based on the Intensive Care Delirium Screening Checklist (ICDSC), together with the coded diagnosis F05 in the International Classification of Diseases (ICD-2019). …”
Get full text

Social determinants of oral health in an indigenous community of Chile: preliminary data of a mixed qualitative and quantitative study by Cynthia Cantarutti, Gerardo Yévenes, Agueda Muñoz-del-Carpio-Toia, Daniela Adorno-Farias, Ricardo Fernández-Ramires, Alan Roger Santos-Silva, Jean Nunes dos Santos, Ignacio Molina-Ávila, Wilfredo Alejandro González-Arriagada

Get full text

Bovine leukemia virus occurrence in Dagestan by N. R. Budulov, M. M. Mikailov, Sh. A. Gunashev, E. A. Yanikova, A. A. Halikov

“…Comparative analysis of serological and molecular genetic methods used for bovine leukosis diagnosis demonstrated the advantage of enzyme-linked immunosorbent assay and polymerase chain reaction as compared to immunodiffusion assay used in veterinary practice.…”
Get full text

Retrospective analysis of trauma patients transported by dispatch monitored type B ambulances to Dhulikhel Hospital, Kavre, Nepal, 2019–2023 by Maxwell L. Mantych, Shiva Neupane, Machchendra Sapkota, Laura D. Cassidy, Sarah C. Young, Ronald Anguzu, Samjhana Basnet

“…Approximately one-third of patients admitted to the hospital after evaluation in the emergency department experienced multiple injuries, and the most prevalent diagnosis of admitted cases were extremity fractures (52%). …”
Get full text

Flow cytometric characterisation of acute leukaemia in adolescent and adult Ethiopians by Jemal Alemu, Balako Gumi, Aster Tsegaye, Abdulaziz Sherif, Fisihatsion Tadesse, Amha Gebremedhin, Rawleigh Howe

“…What this study adds: This study extends previous studies by describing phenotypically defined subsets of ALL and AML which, in addition to diagnosis, may have useful prognostic value for clinicians.…”
Get full text

Air Medical Transportation for Severe Acute Pancreatitis Patients over an Extra Long Distance: Is It Safe Enough? by Lin Gao, Jingzhu Zhang, Kun Gao, Yiyuan Pan, Xiaotao Qin, Jie Zhang, Jing Zhou, Guotao Lu, Weiqin Li, Zhihui Tong

“…It is important for SAP patients to receive centralized diagnosis and treatment in an experienced tertiary center. …”
Get full text

In-hospital costs of diabetic foot infection at a national referral hospital in Jakarta, Indonesia by Fitrianingsih, Rani Sauriasari, Em Yunir, Agusdini Banun Saptaningsih

“…Data were taken from the medical admissions record unit, electronic health records (EHR), hospital integrated system (HIS) and the foot registry system in the metabolic endocrine division, in relation to diabetic foot infection (DFI) as the primary or secondary diagnosis. We analysed data referring to patient characteristics, in-hospital costs and length of stay (LOS), with further comparison based on amputation status. …”
Get full text