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12321
Infections with Giardia duodenalis and Entamoeba histolytica/Entamoeba dispar as Hidden and Prevalent Conditions in Periurban Communities in the State of Rio de Janeiro, Brazil
Published 2020-01-01“…In addition, people residing in houses with more than four inhabitants showed significantly higher positivity for infections with G. duodenalis and with E. histolytica/E. dispar (22/138 (15.9%) vs. 16/311 (5.1%); PR = 3.09; 95% CI = 1.68–5.71; p<0.001 for G. duodenalis and 32/138 (23.2%) vs. 30/311 (9.6%); PR = 2.40; 95% CI = 1.52–3.79; p<0.001 for E. histolytica/E. dispar). Laboratory diagnosis of protozoan enteric infections and effective drugs for their treatment are unmet goals in the primary health care system. …”
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12322
Glycyrrhizinate Monoammonium Cysteine-Loaded Lipid Nanoparticles Allow for Improved Acute Liver Injury Therapy
Published 2025-01-01“…<b>Conclusions:</b> Our results suggest that LNPs offer an enhanced therapeutic approach for ALI treatment, reducing the required drug dosage, and <sup>68</sup>Ga-FAPI PET/CT imaging provides a novel method for diagnosis and treatment assessment. This study contributes valuable insights into the utilization of LNPs in liver disease treatment, presenting a promising direction for future clinical applications.…”
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12323
MUC1 and glycan probing of CA19-9 captured biomarkers from cyst fluids and serum provides enhanced recognition of ovarian cancer
Published 2025-01-01“…Abstract Glycosylation changes of circulating proteins carrying the CA19-9 antigen may offer new targets for detection methods to be explored for the diagnosis of epithelial ovarian cancer (EOC). Search for assay designs for targets initially captured by a CA19-9 antigen reactive antibody from human body fluids by probing with fluorescent nanoparticles coated with lectins or antibodies to known EOC associated proteins. …”
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12324
Long-Term Monitoring of Liver Fibrosis and Steatosis in Patients with Chronic Hepatitis C after Achieving a Sustained Virologic Response to Antiviral Therapy
Published 2023-02-01“…The data obtained indicate the feasibility of routine diagnosis of both fibrosis and steatosis of the liver in the management of patients with chronic HCV infection before and after successful antiviral therapy.…”
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12325
Serum IL-18 Is a Potential Biomarker for Predicting Severe Dengue Disease Progression
Published 2021-01-01“…A 24-plex panel of cytokines/chemokines was evaluated to measure the plasma levels of targeting factors in dengue patients with an MDF and SDD diagnosis without or with comorbidities. As identified in sixteen kinds of cytokines/chemokines, ten were significantly (P<0.05) (10/16) increased, one was significantly (P<0.01) (1/16) decreased, and five were potentially (5/16) altered in all dengue patients (n=30) in the acute phase of disease onset. …”
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12326
Risk Factors and Changes of Peripheral NK and T Cells in Pulmonary Interstitial Fibrosis of Patients with Rheumatoid Arthritis
Published 2019-01-01“…To investigate the clinical risk factors, especially the changes of lymphocyte subsets, in RA-ILD in order to make early diagnosis and achieve prevention of the pulmonary interstitial lesions. …”
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12327
Morphological features of autoimmune gastritis
Published 2014-07-01“…Involvement of antral region was revealed in all patients, in 4 cases it has been related to presence of H. pylori infection at the moment of investigation. Thus, the diagnosis of AIG was based mainly on elevated level antiparietal cells antibodies at blood serum test.…”
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12328
Clinical Characteristics of Early-Onset and Late-Onset Multiple Sclerosis in Patients from Lithuania
Published 2025-01-01“…The EOMS group experienced more clinical relapses in the first year after diagnosis, along with more frequent radiological signs of disease activity compared to LOMS (<i>p</i> < 0.001). …”
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12329
Detecting Atrial Fibrillation Using Smartwatches
Published 2025-02-01“…Smartwatches are a promising tool supporting the diagnosis of cardiac arrhythmias and monitoring already diagnosed diseases. …”
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12330
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12331
Idiopathic pulmonary fibrosis is a risk factor for cardiovascular disease: potential role of KL-6 and systemic inflammation
Published 2025-01-01“…Methods This prospective case–control study was performed on 134 IPF patients above 18 years. Diagnosis of IPF was based on diagnostic radiologic criteria addressed by ATS guidelines. …”
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12332
Postoperative Ratio of C-Reactive Protein to Albumin as a Predictive Marker in Patients with Crohn’s Disease Undergoing Bowel Resection
Published 2021-01-01“…The cutoff values and the accuracy of diagnosis for the CAR and postoperative CRP levels were examined with receiver operating characteristic (ROC) curves. …”
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12333
Informatics strategies for early detection and risk mitigation in pancreatic cancer patients
Published 2025-02-01“…This review provides a comprehensive overview of the current landscape in pancreatic cancer (PC) screening, diagnosis, and early detection. This emphasizes the need for targeted screening in high-risk groups, particularly those with familial predispositions and genetic mutations, such as BRCA1, BRCA2, and PALB2. …”
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12334
Model Prognosis Masa Pengobatan Pasien Tuberkulosis Dengan Metode C4.5
Published 2023-12-01“…Abstract Tuberculosis patients have a relatively diverse treatment period because of the level of compliance of each patient to take the drug until it runs out and the time period has been determined by the Pulmonary Specialist. If a wrong diagnosis is related to drug dosage, it will increase health risk factors, namely where the treatment process will take more time and longer due to the Multi-Drug Resistant condition. …”
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12335
Low body mass index as a predictor of sputum culture conversion and treatment outcomes among patients receiving treatment for multidrug-resistant tuberculosis in Lesotho
Published 2024-12-01“…This will require a multipronged approach focused on alleviating food insecurity and enabling prompt diagnosis and treatment of HIV and TB.…”
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12336
The Advances in Utilizing Right Ventricular Function as a Predictor of Peripartum Cardiomyopathy Recovery: A Single Centre Prospective Cohort Study
Published 2025-01-01“…Among all RV function parameters, only FAC (OR 1.076; 95% CI:1.003– 1.154; p = 0.040)) and RVGLS (OR 0.768; 95% CI: 0.595– 0.991; p = 0.042) emerged as independent predictors of PPCM recovery.Conclusion: Right ventricular function in terms of FAC and/or RVGLS at initial diagnosis can be used as a predictor for PPCM recovery at 6 months follow-up.Keywords: FAC, PPCM, right ventricle, RVGLS…”
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12337
A case of de novo neuroendocrine prostate cancer presented with elevated level of serum CEA carrying BRCA2 mutation: case report and literature review
Published 2025-01-01“…Potential circulating or fluid markers might facilitate early diagnosis thus improving prognosis of NEPC, especially for de novo NEPC.Case presentationA man of 71-year was presented with elevated level of serum carcinoembryonic antigen (CEA) (1296.5 ng/ml) and normal PSA (0.47ng/ml). …”
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12338
Association between colorectal cancer and arthritis among Americans in 2005–2016
Published 2025-01-01“…Therefore, the correlation between arthritis and CRC was investigated to provide some theoretical support for understanding the prevention and diagnosis of CRC. Methods This study utilized data from the National Health and Nutrition Examination Survey (NHANES) to investigate the relationship between arthritis and CRC among Americans. …”
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12339
Investigating the Role of Gut Microbiota in Pediatric Patients with Severe COVID-19 or MIS-C
Published 2025-01-01“…An in-depth evaluation of lesser-known gut species may be key to reducing the risk of severe outcomes and developing microbiota-based biomarkers for the early diagnosis of MIS-C.…”
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12340
Global, regional and national epidemiological trends of multiple myeloma from 1990 to 2021: a systematic analysis of the Global Burden of Disease study 2021
Published 2025-01-01“…Targeted preventive interventions and improvements in diagnosis, treatment, and care are critical, especially in underdeveloped regions, to address the growing global burden of MM.…”
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