Bortezomib, thalidomide, and dexamethasone versus thalidomide and dexamethasone for response rates in multiple myeloma patients: a retrospective study by Juan M. Cano-Calderón, Juan F. Zazueta-Pozos, Adán G. Gallardo-Rodríguez, Carlos Martínez-Murillo, Irma Olarte-Carrillo, Adolfo Martínez-Tovar, Christian O. Ramos-Peñafiel

“…The most common type of MM was immunoglobulin G kappa (79.5%), and 51.8% had an International Staging System score of 3. At diagnosis, 28.9% had renal failure, and 42.2% had albumin levels < 3 g/dL. 37.3% were treated with the TD regimen, whereas 62.7% received the VTD regimen. …”
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A Retrospective Evaluation of the Utility of Capsule Endoscopy and Double-Balloon Endoscopy in Crohn’s Disease by Masanao Nakamura, Yoshiki Hirooka, Osamu Watanabe, Takeshi Yamamura, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto

“…Although the usefulness of capsule endoscopy (CE) and double-balloon endoscopy (DBE) for the evaluation of Crohn’s disease (CD) is established, their capabilities in the differential diagnosis of small bowel stenosis have not been sufficiently addressed. …”
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Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications by Pharaoh Fellow Mwale, Cheng-Ta Hsieh, Ting-Lin Yen, Jing-Shiun Jan, Rajeev Taliyan, Chih-Hao Yang, Wen-Bin Yang

“…In addition to its role in disease pathology, CHI3L1 has emerged as a promising biomarker for the diagnosis and monitoring of brain disorders. Elevated cerebrospinal fluid (CSF) levels of CHI3L1 have been linked to disease severity and cognitive decline, particularly in AD and MS, highlighting its potential for clinical diagnostics. …”
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Portal Hypertensive Polyps as Gastroscopic Finding in Liver Cirrhosis by Firdevs Topal, Sabiye Akbulut, Cengiz Karahanlı, Süleyman Günay, Elif Sarıtaş Yüksel, Fatih Esad Topal

“…Standard histological criteria were used in polyp diagnosis. Results. A total of 400 individuals were included in the study. …”
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A mixed methods study investigating factors affecting adherence to Plasmodium vivax malaria primaquine radical cure regimens among migrants along the Myanmar-Thailand border. by April T Ansari, Ko Ko Aung, Htun Htun Win, Candy Beau, Be Nu, Nay Lin Soe, Klay Htoo, Thida San, Tha Gay Wah, Arunrot Keereevijit, Aung Pyae Phyo, Kesinee Chotivanich, Nicholas J White, François Nosten, Ahmar H Hashmi, Cindy S Chu

“…According to the health belief model, prioritizaton of work reduced seeking diagnosis and completing treatment, and often outweighed facilitating factors such as malaria literacy, health education, and social norms; and affected the perceived susceptibility and severity of P. vivax infections.…”
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Clinical Characteristics of Inpatients with Diabetic Foot Ulcer Admitted with Non-Ulcer Complaints: A Retrospective Study by Li L, Li Y, Qin S, Zeng J, Ma W, Wei D

“…This study intends to describe their clinical characteristics, and clarify the problems existing in the DFU management process.Methods: In this retrospective study, admission complaints were determined by combining the final diagnosis and clinical documentation, and were categorized as: ulcer-related or non-ulcer complaints.Results: A total of 264 DFU inpatients were included in the final analysis, of which, 80 (30.3%) were admitted with non-ulcer complaints. …”
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Association between retinal markers and cognition in older adults: a systematic review by Gerald Liew, Bamini Gopinath, Joyce Chan, Joyce Siette, Varshanie Jeevakumar, Rebekah Sefton, Tejal M Shah

“…Objectives To appraise the existing literature reporting an association between retinal markers and cognitive impairment in adults aged 65 years and over and to provide directions for future use of retinal scanning as a potential tool for dementia diagnosis.Design Systematic review of peer-reviewed empirical articles investigating the association of retinal markers in assessing cognitive impairment.Data sources Three electronic databases, Medline, PsycINFO and EMBASE were searched from inception until March 2022.Eligibility criteria All empirical articles in English investigating the association between retinal markers and cognition in humans aged ≥65 years using various retinal scanning methodologies were included. …”
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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

“…The Treatment of Osteogenesis Imperfecta with Parathyroid Hormone and Zoledronic Acid trial will determine if therapy with teriparatide (TPTD) followed by zoledronic acid (ZA) can reduce the risk of clinical fractures in OI.Methods and analysis Individuals aged ≥18 years with a clinical diagnosis of OI are eligible to take part. At baseline, participants will undergo a spine X-ray, and have bone mineral density (BMD) measured by dual-energy X-ray absorptiometry (DXA) at the spine and hip. …”
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Effect of Different Doses of Sugammadex on Recovery and Hemodynamic Parameters in Reversing Neuromuscular Blockade in Patients Undergoing Electroconvulsive Therapy by Kadir ARSLAN, Gozde UCUKSARAC, Hale CETIN ARSLAN, Erkan AYDIN, Ayca Sultan SAHIN

“…While the average number of ECTs applied to the patients was 6.8+-2.8, the average seizure duration was 28.2+-12.7 seconds. The most common diagnosis (32.7%) in patients who underwent ECT was bipolar disorder. …”
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Risk Factors for Cognitive Impairment in Patients with Type 2 Diabetes by Lin Sun, Xue Diao, Xiaokun Gang, You Lv, Xue Zhao, Shuo Yang, Ying Gao, Guixia Wang

“…Together, Glu and Gln levels may represent a good predictive biomarker for the early diagnosis of cognitive impairment in T2DM patients.…”
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Clinical Dental Midline Shift Is Not a Predictor of the Side of Shorter Hemimandible: A Cone Beam Computed Tomography Diagnostic Study by Lígia Pereira da Silva, Alicia López-Solache, Urbano Santana-Penín, José López-Cedrún, María Jesus Mora, Pablo Varela-Centelles, Antonio González-Mosquera, Almudena Rodríguez-Fernández, Urbano Santana Mora

“…Tomographic images were acquired using the i-CAT^® Imaging System; mandibular/maxillary measurements were obtained with the Planmeca Romexis^® software v.6.This is an ancillary study of a clinical trial (NCT02144233) that included chronic pain (TMD diagnosis; DC/TMD criteria), fully dentate, and stable normo-occlusion participants. …”
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Pulp stones and kidney stones-related gene: An investigation of single nucleotide polymorphisms in the gene encoding parathyroid hormone by Prescila Mota de Oliveira Kublitski, Bruna de Souza Romano, Vania Gomes Moraes, Manoel Damião Sousa-Neto, Lívia Azeredo Alves Antunes, Erika Calvano Küchler, Leonardo Santos Antunes, João Armando Brancher, Edgard Michel-Crosato, Marilisa Carneiro Leão Gabardo

“…Methods: This cross-sectional study included adults of both sexes, divided into groups: with PS and without PS. PS diagnosis was based on radiographic evaluation. Saliva samples were collected from all participants, and prior history of KS was recorded. …”
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Preoperative Quality of Life in Patients with Small Vestibular Schwannomas by Matthias Scheich, Lisa Schultes, Manuel Stöth, Jens-Holger Krannich, Rudolf Hagen, Stephan Hackenberg, Miriam Bürklein

“…Due to the improved availability and quality of magnetic resonance imaging diagnostics, even small tumors can be diagnosed at an early stage. The fact that the diagnosis of a VS might negatively affect a patient’s quality of life (QoL) should be taken into consideration when informing patients about various treatment options. …”
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Molecular Detection and Genetic Characterization of Avian Leukosis Virus From Field Outbreaks in Bangladesh by Md. Golzar Hossain, Riman Pathan, SM Nazmul Hasan, Anandha Mozumder, Moslema Jahan Mou, Marjana Akter, Chandan Sikder, Riyan Al Islam Reshad, Roni Mia, Sukumar Saha, Tofazzal Islam, Sharmin Akter

“…A total of 14 liver samples were collected from the suspected layer flocks in Bangladesh. The diagnosis of ALV infection in chickens was confirmed through necropsy, histopathological examinations, reverse transcription‐polymerase chain reaction (RT‐PCR), and sequence analysis. …”
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Causes and Clinical Characteristics of Small Bowel Bleeding in Northern Vietnam by Cong Long Nguyen, Khac Khiem Pham, Canh Hiep Nguyen, Hoang Nam Nguyen, Tran Tien Dao, Hoai Nam Nguyen, The Phuong Nguyen, Van Tuyen Pham, Tuan Thanh Nguyen, Anh Tuan Vu, Truong Khanh Vu

“…Detailed clinical data, diagnosis procedures, and causes of bleeding were collected. …”
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Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project by Wasat Mansoor, Stuart Ferguson, Victoria Ross, Denis Talbot

“…We conducted a UK-wide clinician survey to assess current practice for the diagnosis, management, and follow-up of patients with TC/AC and descriptively compared management between European Neuroendocrine Tumor Society (ENETS) accredited centres of excellence (CoE) and nonaccredited centres (non-CoE). …”
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Artificial intelligence links CT images to pathologic features and survival outcomes of renal masses by Ying Xiong, Linpeng Yao, Jinglai Lin, Jiaxi Yao, Qi Bai, Yuan Huang, Xue Zhang, Risheng Huang, Run Wang, Kang Wang, Yu Qi, Pingyi Zhu, Haoran Wang, Li Liu, Jianjun Zhou, Jianming Guo, Feng Chen, Chenchen Dai, Shuo Wang

“…Abstract Treatment decisions for an incidental renal mass are mostly made with pathologic uncertainty. Improving the diagnosis of benign renal masses and distinguishing aggressive cancers from indolent ones is key to better treatment selection. …”
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Considering Comorbidities and Individual Differences in Testing a Gaming Behavioral Activation App for Perinatal Depression and Anxiety: Open Trial Pilot Intervention Study by Gabriella E Hamlett, Chloe Schrader, Craig Ferguson, Lauren A Kobylski, Rosalind Picard, Joseph J Locascio, Richard J McNally, Lee S Cohen, Rachel Vanderkruik

“…ResultsWhen controlling for baseline symptoms, results revealed a significant interaction between baseline diagnosis and the quadratic component of study week on anxiety (β=.18, SE 0.07; t62Pt68Pt13P ConclusionsThe app was beneficial in reducing depression symptoms in perinatal individuals with different comorbidity profiles. …”
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Clinical Value of Asymmetrical Dimethylarginine Detection in Patients with Connective Tissue Disease-Associated Pulmonary Arterial Hypertension by Juan Liu, Qiang Fu, Lili Jiang, Youlian Wang

“…The levels of ADMA in the serum may contribute to be a noninvasive indicator for early diagnosis of CTD-with PAH patients.…”
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Oral phenotype and scoring of vascular Ehlers–Danlos syndrome: a case–control study by Lisa Golmard, Ariane Berdal, François Côme Ferré, Michael Frank, Bruno Gogly, Adrien Naveau, Hafida Chérifi, Joseph Emmerich, Frédérick Gaultier, Xavier Jeunemaitre, Benjamin P J Fournier

“…Difficulty of clinical diagnosis has led to the design of diagnostic criteria, summarised in the Villefranche classification. …”
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