Two Novel CYP11B1 Gene Mutations in Patients from Two Croatian Families with 11β-Hydroxylase Deficiency by Katja Dumic, Tony Yuen, Zorana Grubic, Vesna Kusec, Ingeborg Barisic, Maria I. New

“…Here, we describe the molecular genetics of two previously reported male siblings in whom diagnosis of 11β-OHD has been established based on their hormonal profiles displaying high levels of 11-deoxycortisol and hyperandrogenism. …”
Get full text

International perspective on healthcare provider gender bias in musculoskeletal pain management: a scoping review protocol by Katherine Fisher Wilford, Maria Jesus Mena-Iturriaga, Margaret Vugrin, Macarena Wainer, Phillip S Sizer, Gesine Hendrijke Seeber

“…Therefore, this study aims to systematically: (1) identify and map the available scientific and grey literature as it relates to healthcare provider gender bias in the assessment, diagnosis and management of (chronic) musculoskeletal pain and (2) identify current gaps that necessitate further research.Methods and analysis This scoping review will be conducted in accordance with recent guidelines, and the results will be reported via the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews. …”
Get full text

Clinical and Economic Outcomes in Low-risk Pulmonary Embolism Patients Treated with Rivaroxaban versus Standard of Care by W. Frank Peacock, Craig I. Coleman, Phil Wells, Gregory J. Fermann, Li Wang, Onur Baser, Jeff Schein, Concetta Crivera

“…# Study Design Adult patients with continuous health plan enrollment for ≥12 months pre- and 3 months post-inpatient PE diagnosis (index date=discharge date) between October 1, 2011- June 30, 2015 and an anticoagulant claim during the index hospitalization were included…”
Get full text

Case study of a neuroendocrine tumor of uncertain origin: single-cell transcriptomics unravels potential primary location by Frolova Tatyana, Ekaterina Avsievich, Diana Salimgereeva, Zoia Antysheva, Alesia Maluchenko, Denis Maksimov, Ilia Feidorov, Mark Voloshin, Olga Glazova, Natalia Bodunova, Nikolay Karnaukhov, Pavel Volchkov, Julia Krupinova

“…Abstract Purpose Determining the primary origin of non-organ-confined neuroendocrine tumors (NETs) for accurate diagnosis and management. Neuroendocrine tumors are rare neoplasms with diverse clinical behaviors. …”
Get full text

The role of Physical environment in influencing access to medical services by people with disabilities in Kisiizi Hospital, Rukungiri District. by Atuheire, Excellent

“…The study findings revealed that effective communication between healthcare providers and patients is crucial for proper diagnosis and treatment hence this accounted for 22% of the respondents. …”
Get full text

Morphometric Study of Suprascapular Notch and Scapular Dimensions in Ugandan Dry Scapulae with Specific Reference to the Incidence of Completely Ossified Superior Transverse Scapul... by Adewale, Adesanya Olamide, Segun, Okeniran Olatayo, Usman, Ibe Michael, Monima, Ann Lemuel, Kegoye, Eric Simidi, Keneth Iceland, Kasozi, Nalugo, Halima, Ssempijja, Fred

“…Background: Understanding of suprascapular notch (SSN) anatomy and relationship with scapular dimensions are vital in diagnosis, prevention, and assessment of suprascapular nerve entrapment syndrome. …”
Get full text

Association of glycemic control with Long COVID in patients with type 2 diabetes: findings from the National COVID Cohort Collaborative (N3C) by Jane E B Reusch, Rachel Wong, Nasia Safdar, Harold Lehmann, Brijesh Patel, Til Stürmer, Hongfang Liu, Peter Robinson, Elaine Hill, Richard Moffitt, Justin Guinney, Joel Gagnier, Cavin Ward-Caviness, Noha Sharafeldin, Justin Starren, Amit Saha, Lesley Cottrell, Melissa A Haendel, Margaret A Hall, Vignesh Subbian, Kristin Kostka, Farrukh M Koraishy, Andrew E Williams, Robert Hurley, Steve Johnson, Usman Sheikh, Rishi Kamaleswaran, Christopher Dillon, Michele Morris, Randeep Jawa, Hemalkumar Mehta, Benjamin Bates, Tellen D Bennett, Nabeel Qureshi, Katie Rebecca Bradwell, Federico Mariona, Adam B Wilcox, Adam M Lee, Alexis Graves, Amin Manna, Amy Olex, Andrea Zhou, Andrew Southerland, Andrew T Girvin, Anita Walden, Anjali A Sharathkumar, Benjamin Amor, Brian Hendricks, Caleb Alexander, Carolyn Bramante, Charisse Madlock-Brown, Christine Suver, Christopher Chute, Chunlei Wu, Clare Schmitt, Cliff Takemoto, Dan Housman, Davera Gabriel, David A Eichmann, Diego Mazzotti, Eilis Boudreau Don Brown, Elizabeth Zampino, Emily Carlson Marti, Emily R Pfaff, Evan French, Fred Prior, George Sokos, Greg Martin, Heidi Spratt, Hythem Sidky, JW Awori Hayanga, Jami Pincavitch, Jaylyn Clark, Jeremy Richard Harper, Jessica Islam, Jin Ge, Joel H Saltz, Joel Saltz, Johanna Loomba, John Buse, Jomol Mathew, Joni L Rutter, Julie A McMurry, Karen Crowley, Kellie M Walters, Ken Wilkins, Kenneth R Gersing, Kenrick Dwain Cato, Kimberly Murray, Lavance Northington, Lee Allan Pyles, Leonie Misquitta, Lili Portilla, Mariam Deacy, Mark M Bissell, Marshall Clark, Mary Emmett, Mary Morrison Saltz, Matvey B Palchuk, Meredith Adams, Meredith Temple-O'Connor, Michael G Kurilla, Nicole Garbarini, Ofer Sadan, Patricia A Francis, Penny Wung Burgoon, Rafael Fuentes, Rebecca Erwin-Cohen, Richard A Moffitt, Richard L Zhu, Robert T Miller, Saiju Pyarajan, Sam G Michael, Samuel Bozzette, Sandeep Mallipattu, Satyanarayana Vedula, Scott Chapman, T Shawn, Soko Setoguchi O'Neil, Stephanie S Hong, Tiffany Callahan, Umit Topaloglu, Valery Gordon, Warren A Kibbe, Wenndy Hernandez, Will Beasley, Will Cooper, William Hillegass, Xiaohan Tanner Zhang, Samuel Soff, Yun Jae Yoo, Jared Davis Huling, Daniel Brannock, Zachary Butzin-Dozier, Alfred Jerrod Anzalone, Philip RO. Payne, Rena Patel

“…An NLP-based definition of Long COVID identified more patients than diagnosis codes and should be considered in future studies.…”
Get full text

The clinical value of computed tomography Hounsfield unit for diagnosing palpable inguinal lymph node metastasis in patients with penile cancer by Yu Li, Yu Chen, Gansheng Xie, Gang Li, Huming Yin

“…The average ACE-CT HU (cutoff: 40.5) had the highest accuracy as 0.857, and maximum NC-CT HU (cutoff: 51.5) had the highest sensitivity of 0.897.ConclusionILN CT HU was clinically valuable for the diagnosis of palpable ILN metastasis in patients with newly diagnosed penile cancer.…”
Get full text

Frequency and Risk Factors of Advanced Neoplasia in Korean Inflammatory Bowel Disease Patients with Low-grade Dysplasia by Kyeong Ok Kim, Dong Hyun Kim, Soo-Kyung Park, Division of Gastroenterology, Department of Internal Medicine and Inflammatory Bowel Disease Center, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Chang Kyun Lee, IBD Research Group of the Korean Association for the Study of Intestinal Diseases (KASID)

“…This study evaluated the clinical features, frequency, and risk factors for advanced neoplasia in patients with IBD after an LGD diagnosis. Methods: The medical records of 166 patients with IBD from six university hospitals in Korea from 2010 to 2019 were reviewed retrospectively. …”
Get full text

Clinical characteristics and usage of statins in patients with stable ischemic heart disease referred for angiography or coronary artery bypass grafting by I.V. Shklianka, O.J. Zharinov, К.O. Mikhaliev, O.A. Epanchintseva

Get full text

Maternal and Perinatal Outcome of Triplet Pregnancies in a Tertiary Care Hospital in North India: A Prospective Observational Study by Sabreen Wani, Fiza Amin, Shagufta Yasmeen Rather

“…Conclusion: While triplet pregnancies remain rare, they are associated with a significant materno-foetal risk which must be anticipated by obstetricians. Thus, early diagnosis, adequate antenatal care, counselling, and perinatal care and support can help to ensure optimal outcomes. …”
Get full text

Antidepressant Treatment Response Prediction With Early Assessment of Functional Near-Infrared Spectroscopy and Micro-RNA by Lok Hua Lee, Cyrus Su Hui Ho, Yee Ling Chan, Gabrielle Wann Nii Tay, Cheng-Kai Lu, Tong Boon Tang

“…While functional near-infrared spectroscopy (fNIRS) had previously been suggested for major depressive disorder (MDD) diagnosis, the clinical application to predict antidepressant treatment response (ATR) is still unclear. …”
Get full text

Multiple Comorbidities, Psychiatric Disorders, Healthcare Resource Utilization and Costs Among Adults with Essential Tremor: A Retrospective Observational Study in a Large US Comme... by Dingwei Dai, Ali Samiian, Joaquim Fernandes, Henriette Coetzer

“…The earliest claim date with ET diagnosis was identified as the index date. An index date was assigned randomly for each non-ET patient. …”
Get full text

Scrub Typhus and Influenza A Co-Infection: A Case Report by Chie Yamamoto, Ayano Maruyama, Jun Munakata, Tasuku Matsuyama, Keitaro Furukawa, Ryosuke Hamashima, Motohiko Ogawa, Yuki Hashimoto, Akiko Fukuda, Tohru Inaba, Yoko Nukui

“…The symptoms of scrub typhus are flu-like and nonspecific, which may delay diagnosis and treatment.…”
Get full text

The Relationship between H. pylori Infection and Osteoporosis in Japan by Daisuke Asaoka, Akihito Nagahara, Mariko Hojo, Hitoshi Sasaki, Yuji Shimada, Takashi Yoshizawa, Taro Osada, Sumio Watanabe

“…Participants for patient profile, H. pylori infection status, comorbidity, internal medical therapies, lumbar dual-energy X-ray absorptiometry (DXA), and bone turnover marker were collected and upper gastrointestinal endoscopy for reflux esophagitis, hiatal hernia, peptic ulcer disease (PUD), and endoscopic gastric mucosal atrophy (EGA) was performed. The diagnosis of osteoporosis was performed in accordance with the Japanese criteria. …”
Get full text

Clinical Presentation and Management Strategies in Intraorbital Foreign Bodies by Samreen Khanam, Ayushi Agarwal, Ruchi Goel, Neha Rathie, Akash Raut, Shweta Raghav, Sumit Kumar, Mohit Chhabra, Sonam Singh, Sushil Kumar

“…Computed Tomography scan confirmed the diagnosis in five cases and Magnetic Resonance Imaging (MRI) was diagnostic in one. …”
Get full text

Complications and outcomes in diffuse large B‐cell lymphoma with gastric lesions treated with R‐CHOP by Tomohiro Kadota, Sachiko Seo, Hiroe Fuse, Genichiro Ishii, Kuniaki Itoh, Tomonori Yano, Kazuhiro Kaneko, Kunihiro Tsukasaki

“…A low serum albumin level at diagnosis was the only risk factor identified for gastric complications (P = 0.001) and six of the eight patients with complications were shown to be at stage IV. …”
Get full text

Factors Influencing Treatment-Seeking Behavior Among Caregivers of Children with Cancer: A Scoping Review by Nurhidayah I, Hendriyani D, Adistie F, Nurhaeni N, Mediani HS

“…A key factor contributing to these poor survival rates is the late diagnosis of pediatric cancer, which is often due to insufficient treatment-seeking behaviors by parents. …”
Get full text

The Association between Type 2 Diabetes Mellitus and Thyroid Cancer by Young-Gyun Seo, Ho-Chun Choi, Ah Reum An, Do Joon Park, Young Joo Park, Kyu Eun Lee, Sue K. Park, Yunji Hwang, Belong Cho

“…Individuals with early T2DM are presumed to have a low incidence of thyroid cancer, and this effect seems to last up to 6 years after diagnosis of T2DM.…”
Get full text

In Acute IgA Nephropathy, Proteinuria and Creatinine Are in the Spot, but Podocyturia Operates in Silence: Any Place for Amiloride? by H. Trimarchi, M. Paulero, R. Canzonieri, A. Schiel, A. Iotti, C. Costales-Collaguazo, A. Stern, M. Forrester, F. Lombi, V. Pomeranz, R. Iriarte, T. Rengel, I. Gonzalez-Hoyos, A. Muryan, E. Zotta

“…Whether podocyturia could be employed in IgA nephropathy as a trustable biomarker for treatment assessment or even for early diagnosis of IgA nephropathy relapses should be further investigated.…”
Get full text