Analytical and diagnostic performance characteristics of reverse-transcriptase loop-mediated isothermal amplification assays for dengue virus serotypes 1-4: A scoping review to inf... by Paul Arkell, Dumrong Mairiang, Adisak Songjaeng, Kenny Malpartida-Cardenas, Kerri Hill-Cawthorne, Panisadee Avirutnan, Pantelis Georgiou, Alison Holmes, Jesus Rodriguez-Manzano

“…Reverse-transcriptase (RT) quantitative polymerase chain reaction (qPCR) assays are the current gold-standard in diagnosis and serotyping of infections, but their use in low-middle income countries (LMICs) has been limited by laboratory infrastructure requirements. …”
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U-shaped association between TC/HDL-C ratio and osteoporosis risk in older adults by Chuanwei Zhao, Xiaochun Zhang, Xu Zhang, Bo Zhao, Yane Yang, Mu Lin, Wenli Qiao, Zeyao Hu, Haijie Yang

“…Osteoporosis was defined by self-reported physician diagnosis or dual-energy x-ray absorptiometry (DXA) measurements. …”
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Improved Risk Prediction of Acute Myocardial Infarction in Patients With Stable Coronary Artery Disease Using an Amino Acid-Assisted Model by Yi-Jing Zhao, Yong Li, Feng-Xiang Wang, Hao Lv, Yaoyao Qu, Lian-Wen Qi, Pingxi Xiao

“…Developing a reliable model to predict AMI occurrence in these patients holds the potential to expedite early diagnosis and intervention. This study is aimed at establishing a circulating amino acid-assisted model, incorporating amino acid profiles alongside clinical variables, to predict AMI risk. …”
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Application of metagenomic next-generation sequencing (mNGS) to describe the microbial characteristics of diabetic foot ulcers at a tertiary medical center in South China by Hongteng Xie, Zhaohong Chen, Guohua Wu, Pei Wei, Teng Gong, Shun Chen, Zhaorong Xu

“…Metagenomic next-generation sequencing (mNGS) has been a useful supplement to routine culture method for the etiological diagnosis of DFUs. In this study, we utilized a routine culture method and mNGS to analyze the same DFU wound samples and the results were compared. …”
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The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review by Ambra Di Piazza, Federica Vernuccio, Massimo Costanzo, Laura Scopelliti, Dario Picone, Federico Midiri, Francesco Salvaggi, Francesco Cupido, Massimo Galia, Sergio Salerno, Antonio Lo Casto, Massimo Midiri, Giuseppe Lo Re, Roberto Lagalla

“…The videofluorographic swallowing study is a key diagnostic tool in the detection of swallowing disorders, allowing to make an early diagnosis and to reduce the risk of gastrointestinal and pulmonary complications. …”
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Comprehensive Metabolomic Profiling in Adults with X-Linked Hypophosphatemia: A Case-Control Study by Luis Carlos López-Romero, José Jesús Broseta, Marta Roca-Marugán, Noemí Máñez Ramírez, Julio Hernández-Jaras

“…Background: X-linked hypophosphatemia (XLH) is a rare disorder characterized by elevated levels of fibroblast growth factor 23 (FGF-23), leading to hypophosphatemia and complications in diagnosis due to its clinical heterogeneity. Metabolomic analysis, which examines metabolites as the final products of cellular processes, is a powerful tool for identifying in vivo biochemical changes, serving as biomarkers of pathological abnormalities, and revealing previously uncharted metabolic pathways. …”
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Can Orthodontic Treatment Be Stable 20 Years after the End of the Treatment Scheme? Treatment of a Class 2, Division 1 Malocclusion with Severe Skeletal Discrepancy and Its 20-Year... by Domenico Aiello, Riccardo Nucera, Stefania Costa, Michele Mario Figliuzzi, Sergio Paduano

“…The maintenance of a stable orthodontic result over time is the result not only of a correct and physiological occlusion but also and above all of a correct diagnosis and correct identification of problems that can cause the malocclusion itself. …”
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Impact of Funding Source on Long-Term Outcomes in Prostate Cancer: Analysis of a Large Public Database From Sao Paulo, Brazil by Fernando C. Maluf, Cintia S.K.S. de Oliveira, Patrícia K. Ziegelmann

“…On the basis of clinical characteristics at diagnosis (lymph node status, distant metastasis, prostate-specific antigen [PSA], and Gleason score), patients were categorized into low-risk, intermediate-risk, high-risk, and metastatic groups.RESULTSOf 25,009 patients analyzed, 85% had a public funding source. …”
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Prevalence and Risk Factors for Opioid-Induced Constipation in an Older National Veteran Cohort by Fern FitzHenry, Svetlana K. Eden, Jason Denton, Hui Cao, Aize Cao, Ruth Reeves, Guanhua Chen, Glenn Gobbel, Nancy Wells, Michael E. Matheny

“…OIC was identified through additions/changes in laxative prescriptions, all-cause constipation identification through diagnosis, or constipation related procedures in the presence of opioid exposure. …”
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Distinct subcellular localization of tau and alpha-synuclein in lewy body disease by D. Luke Fischer, Marissa Menard, Omar Z. Abdelaziz, Nicholas M. Kanaan, Virginia G. Cobbs, Richard E. Kennedy, Geidy E. Serrano, Thomas G. Beach, Laura A. Volpicelli-Daley

“…The abundance of p-α-syn, p-tau, and MHCII was significantly associated with diagnosis of LBD. Quantification of colocalization showed that MHCII and Iba1 colocalized, demonstrating activated immune cells are mostly microglia. …”
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Nasal Provocation Test with Cat and Dog Extracts: Results according to Molecular Components by Andres Sánchez, Ricardo Cardona, Marlon Munera, Victor Calvo, Manuela Tejada-Giraldo, Jorge Sánchez

“…IgE sensitization (atopy) to pets is commonly evaluated using pet dander extracts. However, the diagnosis by components seems to be more adequate to evaluate the clinical relevance (allergy) of sIgE sensitization. …”
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Battle of the axes: simulation-based assessment of fine needle aspiration biopsies for thyroid nodules by Shireen Samargandy, Justine Philteos, Mirko Manojlovic Kolarski, Jason Xu, Eric Monteiro, Allan Vescan

“…Abstract Importance Ultrasound-guided fine-needle aspiration biopsies (UGFNA) play a crucial role in the diagnosis of thyroid nodules. There are two techniques for performing an UGFNA: short-axis technique and long-axis technique. …”
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Low-Level Laser Therapy and Calcitonin in Bone Repair: Densitometric Analysis by Tatiana Pinto Ribeiro, Simone Bustamante Nascimento, Claúdia Alessandra Cardoso, Raduan Hage, Janete Dias Almeida, Emilia Angela Loschiavo Arisawa

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An X-Linked Hyper-IgM Patient Followed Successfully for 23 Years without Hematopoietic Stem Cell Transplantation by Necil Kutukculer, Neslihan Edeer Karaca, Guzide Aksu, Ayca Aykut, Erhan Pariltay, Ozgur Cogulu

“…Secondly, type of CD40LG mutations leads to enormous interpatient variations regarding serum IgM levels, CD40LG levels on activated T cells, age at diagnosis, severity of clinical findings, and follow-up therapies with or without hematopoietic stem cell therapy.…”
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Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis by Meng Wang, Licheng Wang, Shusheng Wu, Dongsheng Zhou, Xianming Wang

“…This study is aimed at identifying novel key genes that may be used for hepatocellular carcinoma (HCC) diagnosis, prognosis, and targeted therapy. This study included 3 expression profiles (GSE45267, GSE74656, and GSE84402), which were obtained from the Gene Expression Omnibus (GEO). …”
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“Gleaning a lot from the history and physical exam,” and “reasonably confident without imaging”: a qualitative study of primary care clinicians' management of patients with low bac... by Lynn Haslam-Larmer, Kathleen E. Norman, Andrea M. Patey, Isabella M. Thomas, Michael E. Green, Jeremy M. Grimshaw, Jill A. Hayden, Jan Hartvigsen, Noah M. Ivers, Hazel Jenkins, Simon D. French

“…Some clinicians described the value of imaging to corroborate a diagnosis (domain Beliefs about consequences). Conclusions This study is the first to examine influences on imaging behaviours of a large interprofessional sample of primary care clinicians in Canada. …”
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Models for predicting risk of endometrial cancer: a systematic review by Bea Harris Forder, Anastasia Ardasheva, Karyna Atha, Hannah Nentwich, Roxanna Abhari, Christiana Kartsonaki

“…Papers relating to predicting the risk of a future diagnosis of EC were selected for inclusion. Study characteristics, variables included in the model, methods used, and model performance, were extracted. …”
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Immune Thrombocytopenia in a worker exposed to toluene: a case report by Eric Slawka, Margarida Lourenço Castelló, Gabriel Machado Romão da Silva, Angelica dos Santos Vianna

“…She had bruises on the physical exam, and platelets count of 40.000 µL. A diagnosis of primary ITP aggravated by benzene-contaminated toluene exposure was made. …”
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Reassessment of disease severity routine laboratory tests in the COVID-19 infection by A. A. Simushev, E. Yu. Medvedeva, Yu. O. Shulpekova, V. M. Nechaev, M. R. Skhirtladze, I. R. Popova, V. T. Ivashkin

“…Publications demonstrate some limitations of National Early Warning Score 2 (NEWS-2) accuracy in assessment on coronavirus infection severity.The purpose of this study was to determine the value of the patient’s age and routine laboratory parameters in the assessment of patient’s general condition in coronavirus pneumonia and their relation to NEWS-2 scale parameters.Materials and methods. 50 case reports of patients with COVID-19 infection observed in the Sechenov University in January–March 2021 were analyzed. 34 % of patients were males aged 31 to 89 years (average age 55 years) and 66 % — females aged 40 to 91 (mean age 63). The diagnosis of pneumonia was confirmed by computed tomography. …”
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The relationship between pain, sleep quality, and care dependency in older adults living in a long-term care facility by Grażyna Puto, Anna Kliś-Kalinowska, Agata Musiał

“…Abstract Background Due to the frequency of pain, sleep disorders and the complexity of their associated factors, the diagnosis of these disorders may be of great importance in identifying factors linked to care dependency in older people staying in long-term care facilities. …”
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