New Platform Technology for Comprehensive Serological Diagnostics of Autoimmune Diseases by Annika Willitzki, Rico Hiemann, Vanessa Peters, Ulrich Sack, Peter Schierack, Stefan Rödiger, Ursula Anderer, Karsten Conrad, Dimitrios P. Bogdanos, Dirk Reinhold, Dirk Roggenbuck

“…Antibody assessment is an essential part in the serological diagnosis of autoimmune diseases. However, different diagnostic strategies have been proposed for the work up of sera in particular from patients with systemic autoimmune rheumatic disease (SARD). …”
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Effectiveness, toxicity and impact on quality of life of high-dose-rate brachytherapy delivered in two fractions as monotherapy in patients with prostate cancer by Johan Staby Olsén, Antonis Valachis, Bengt Johansson

“…PSA exceeding 10 ng/mL at diagnosis was a significant risk factor for BCR (Odds Ratio (OR) = 3.29, 95 % CI: 1.01–10.67) whereas PSA of ≤0.1 ng/ml as nadir was a significant positive prognostic factor, associated with lower risk of BCR (OR = 0.11, 95 % CI: 0.03–0.33). …”
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The Pathophysiology and Management of Coprophagia: A Report of Two Cases and Literature Review by Heela Azizi, Tasmia Khan, Cecilia Canale, Jisha Kallikkadan, Ivan Leung, Alexa Kahn, Dina Rimawi, Shantale Williams, Chidubem Matthew Obegolu, Sharon Paul, Shazia Chaudhry, Chiedozie Ojimba, Kodjovi Kodjo, Olaniyi Olayinka, Oluwole Jegede, Ayodeji Jolayemi

“…Recent and pertinent literature was reviewed and the implications for diagnosis and management of coprophagia are discussed.…”
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Pediatric pancreatic acinar cell carcinoma with a non-canonical BRAF-KMT2C fusion and a classic SND1-BRAF fusion: a case report and literature review by Yaqin Wang, Jiasi Zhang, Dimin Nie, Ai Zhang, Qun Hu, Aiguo Liu

“…Pathological and imaging evidence confirmed the diagnosis of PACC, with no lymph node infiltration or distant metastasis. …”
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Integrating High-Value Cost-Conscious Care into an Existing Medical School Curriculum by Sruthi Eapen, Aylmer Tan, Paul Gorman, Gretchen Scholl, Andrea Smeraglio

“…The curricula comprised three spaced asynchronous online sessions targeting HVCCC skill development followed by a gamified 90-minute clinical skills lab where students competed to determine the correct diagnosis at the lowest cost. Results One hundred and twenty-three medical students (out of 145 first-year medical students) completed the presurvey and indicated willingness to participate in the educational innovation, and 54 completed both surveys. …”
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Development and validation of highly sensitive multiplex real-time RT-PCR assay for detection of classical swine fever virus genome by A. S. Sadchikova, A. S. Igolkin, R. S. Chernyshev, A. A. Kozlov, I. S. Kolbin, A. V. Sprygin, D. A. Biryuchenkov, I. A. Chvala, A. Mazloum

“…Therewith, there sults of analysis of test systems No. x1, x2 based on above parameters were lower that could give rise to false positive real-time RT-PCR results and incorrect diagnosis. Thus, described assay can be used for extensive monitoring of classical swine fever in the Russian Federation…”
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Preconceptional brain structure and future conception: a prospective brain MRI study among 321 women by Merel W. de Vries, Eline M. P. Poels, Gennady V. Roshchupkin, Ryan L. Muetzel, Milan Zarchev, Astrid M. Kamperman, Henning Tiemeier, Meike W. Vernooij, Steven A. Kushner

“…Logistic regression was used to examine associations between global brain parameters and conception, adjusting for age, intracranial volume, BMI, prior STD diagnosis, ethnicity, education, household income, smoking, and alcohol use. …”
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Impact of Admission Blood Glucose on Coronary Collateral Flow in Patients with ST-Elevation Myocardial Infarction by Ozge Kurmus, Turgay Aslan, Berkay Ekici, Sezen Baglan Uzunget, Sukru Karaarslan, Asli Tanindi, Aycan Fahri Erkan, Ebru Akgul Ercan, Celal Kervancıoglu

“…We retrospectively evaluated 190 consecutive patients with a diagnosis of first STEMI within 12 hours of onset of chest pain. …”
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Tale of two zones: investigating the clinical outcomes and research gaps in peripheral and transition zone prostate cancer through a systematic review and meta-analysis by Pedro Oliveira, Robert G Bristow, Ananya Choudhury, Ashwin Sachdeva, Noel Clarke, Hitesh Mistry, Amin Ali, Thiraviyam Elumalai, BhanuPrasad Venkatesulu, Lauren Hekman, Esther Baena

“…PZ tumours presented higher Gleason group and T staging more frequently, while TZ tumours were associated with higher prostate specific antigen levels at diagnosis.Conclusion PZ tumours were associated with poorer prognostic clinical features and outcomes. …”
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Haploidentical stem cell transplantation with posttransplant cyclophosphamide in children with Wiskott–Aldrich syndrome: a case report by Le Nguyen Ngoc Quynh, Binh Nguyen Thanh, Lien Luong Thi, Thuy Nguyen Thi Dieu, Duong Dang Anh, Pamela P. Lee, Tung Cao Viet, Dien Tran Minh

“…A 3-month-old boy presented with widespread eczema, a low platelet count, and severe infections in infancy. The diagnosis of WAS was quickly confirmed by genetic test. …”
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Point prevalence survey of antibiotics in a pediatric tertiary hospital in the Republic of Panama by Ximena Norero, Dora Estripeaut, Elizabeth Castaño, Jacqueline Levy, Paola Lichtenberger, José Pablo Díaz-Madriz, José Luis Bustos, Robin Rojas Cortés, Gabriel Levy-Hara

“…The findings suggest it is necessary to assess the need for ampicillin, gentamicin, and piperacillin-tazobactam use in patients admitted to pediatric critical care units, with special emphasis on children with pneumonia and sepsis diagnosis, the most common pathologies for which an antimicrobial was prescribed.…”
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Maternal and Perinatal Outcome of Triplet Pregnancies in a Tertiary Care Hospital in North India: A Prospective Observational Study by Sabreen Wani, Fiza Amin, Shagufta Yasmeen Rather

“…Conclusion: While triplet pregnancies remain rare, they are associated with a significant materno-foetal risk which must be anticipated by obstetricians. Thus, early diagnosis, adequate antenatal care, counselling, and perinatal care and support can help to ensure optimal outcomes. …”
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FABP4 and I-FABP Levels in Pregnant Women Are Associated with Body Mass Index but Not Gestational Diabetes by Tamara Vorobjova, Aili Tagoma, Ija Talja, Helis Janson, Anne Kirss, Raivo Uibo

“…FABP4 and I-FABP levels were not dependent on the diagnosis of GDM, but rather on BMI. The correlation of I-FABP with adiponectin and resistin levels in women with GDM may suggests the importance of lipid metabolism in GDM-associated changes in intestinal permeability.…”
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Time to Relapse and Relapse Predictors in Patients with Schizophrenia at Ayder Comprehensive Specialized Hospital, Northern Ethiopia by Habtamu Endashaw Hareru, Kebede Embaye Gezae, Daniel Sisay W/tsadik, Gebremedhin Berhe Gebregergs

“…Finally, after confirming the model’s diagnosis and assumptions, factors with a p value of less than 0.05 were declared to be statistically significant predictors of schizophrenia relapse. …”
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NON-FUNCTIONING SPORADIC PANCREATIC NEUROENDOCRINE TUMOR IS AN INDEPENDENT RISK FACTOR FOR RECURRENCE AFTER SURGICAL TREATMENT by Estela Regina Ramos Figueira, André Luis Montagnini, Jessica Okubo, Ana Gabriela Vivarelli Fernandes, Marina Alessandra Pereira, Ulysses Ribeiro Junior, Paulo Herman, José Jukemura

“…Their incidence is rising, largely due to the widespread use of high-resolution imaging techniques, particularly influencing the diagnosis of sporadic non-functioning tumors, which account for up to 80% of cases. …”
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Using Machine Learning to Predict Progression in the Gastric Precancerous Process in a Population from a Developing Country Who Underwent a Gastroscopy for Dyspeptic Symptoms by Susan Thapa, Lori A. Fischbach, Robert Delongchamp, Mohammed F. Faramawi, Mohammed S. Orloff

“…We also observed that a diagnosis of no gastritis, superficial gastritis, or antral diffuse gastritis at baseline was a predictor of no progression in the gastric precancerous process. …”
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Influence of Life Style Factors on Barrett’s Oesophagus by A. Horna Strand, T. Franzén

“…Also, potential gender differences and diagnosis of ACO were studied. Results. Mean percentage reflux time on 24 hr-pH-metry was higher for the Barrett’s oesophagus group, 18% for women and 17% for men compared to 4% for women and 4% for men in the control group (P<0.05). …”
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Morphological, Morphometrical and Radiological Features of the Pelvic Limb Skeleton in African Green Monkeys (<i>Chlorocebus sabaeus</i>) from Saint Kitts and Nevis Islands by Cristian Olimpiu Martonos, Alexandru Ion Gudea, Gilda Rawlins, Florin Gheorghe Stan, Calin Lațiu, Cristian Constantin Dezdrobitu

“…For each of the elements, several morphological aspects are described, pointing to the specific and differential aspects that might serve as landmarks in the specific diagnosis of different adaptative changes, related to the type of locomotion. …”
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Hepatocellular Carcinoma with Both Fibrolamellar and Classical Components: An Unusual Morphological Pattern by Diana Castro-Villabón, Luis E. Barrera-Herrera, Paula A. Rodríguez-Urrego, Rachel Hudacko, Alonso Vera, Johanna Álvarez, Rafael Andrade, Rocío López

“…The morphological features and immunohistochemical studies were consistent with a diagnosis of FLC mixed with classical HCC. The patient was followed up for five months, and no signs of recurrence were evident.…”
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Pyogenic Lumbar Facet Joint Infection with Foot Drop by Haruka Maehara, Toshihiro Sano, Yuki Yanagawa, Kyuichi Hashimoto, Nobuaki Tadokoro

“…Clinical suspicion of this condition is a key for diagnosis. We report a case of PFJI which required decompression surgery for severe neurological dysfunction. …”
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