A Drug-Induced Acute Pancreatitis Retrospective Study by Ann-Lorie Gagnon, Alexandre Lavoie, Marie-Pier Frigon, Alban Michaud-Herbst, Karine Tremblay

“…The lack of convincing and conclusive data on drug-induced AP (DIAP) complicates the diagnosis as well as the identification of the causative drug. …”
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Prevalence and spectrum of haemoglobinopathies in females of reproductive age group- A first tertiary care center experience in Punjab, North India by Vikram Narang, Anshul Jain, Sumit Grover, Ankita Soni, Monika Narang, Ashima Taneja

“…Conclusion: Preventive strategies are cost-effective and include population screening, premarital screening, screening of spouses, genetic counseling, and prenatal diagnosis. Educating the carrier females about the potential risk and various screening methods may help in controlling the disease.…”
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Apnea-Hypopnea Index in Chronic Obstructive Pulmonary Disease Exacerbation Requiring Noninvasive Mechanical Ventilation with Average Volume-Assured Pressure Support by Killen H. Briones-Claudett, Adela Romero Lopez, Mónica H. Briones-Claudett, Mariuxi del Pilar Cabrera Baños, Killen H. Briones Zamora, Diana C. Briones Marquez, Andrea P. Icaza-Freire, Luc J. I. Zimmermann, Antonio W. D. Gavilanes, Michelle Grunauer

“…During the study period, a total of 100 patients were admitted to the ICU with a diagnosis of acute hypercapnic respiratory failure due to COPD exacerbation. 72 patients presented with acute respiratory failure and fulfilled criteria for ventilatory support. …”
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Identification of HNF4A Mutation p.T130I and HNF1A Mutations p.I27L and p.S487N in a Han Chinese Family with Early-Onset Maternally Inherited Type 2 Diabetes by Ying Yang, Tai-Cheng Zhou, Yong-Ying Liu, Xiao Li, Wen-Xue Wang, David M. Irwin, Ya-Ping Zhang

“…Mutation p.T130I was associated with both early-onset and late-onset diabetes and caused downregulated HNF4A expression, whereas HNF1A polymorphisms p.I27L and p.S487N were associated with the age of diagnosis of diabetes. We demonstrated that mutation p.T130I in HNF4A was pathogenic as were the predicted polymorphisms p.I27L and p.S487N in HNF1A by genetic and functional analysis. …”
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Pulmonary Embolism in the Elderly: From Symptoms to Speckle Tracking Echocardiography by Christos Ballas, Dimitrios Sfairopoulos, Ioanna Samara, Lampros Lakkas, Olga Kardakari, Athanasios Konstantinidis, Katerina K. Naka, Lampros K. Michalis, Christos S. Katsouras

“…Compared to younger patients, elderly patients with PE had less frequently pain and typical symptoms and more often were hospitalized due to another reason before the PE diagnosis. The elderly had higher values of D-dimer, high-sensitivity troponin I and brain natriuretic peptide (BNP). …”
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Postpartum Tuberculosis: A Diagnostic and Therapeutic Challenge by Vijay Kodadhala, Alemeshet Gudeta, Aklilu Zerihun, Odene Lewis, Sohail Ahmed, Jhansi Gajjala, Alicia Thomas

“…Appropriate treatment is pivotal to curtail morbidity and mortality. TB diagnosis or exposure to active TB can be emotionally distressing to the mother. …”
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Anti-Tick-Bourne Encephalitis IgM Intrathecal Synthesis as a Prediction Marker in Tick-Borne Encephalitis Patients by Piotr Czupryna, Sambor Grygorczuk, Agnieszka Siemieniako-Werszko, Jakub Okrzeja, Justyna Dunaj-Małyszko, Justyna Adamczuk, Sławomir Pancewicz, Joanna Zajkowska, Karolina Narejko, Joanna Oklińska, Gabriela Trojan, Anna Moniuszko-Malinowska

“…The aim of this study was to evaluate the usefulness of IgM anti-Tick-Borne Encephalitis (anti-TBE) intrathecal synthesis in the diagnosis and prediction of the clinical course of the disease. …”
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Do We Need A Bone Block Procedure in Recurrent Anterior Shoulder Instability?: A Case Report by Hastomo Agung Wibowo, Dadang Rona Sasetyo, Yusa muhammad Thoriq, Felix Giovanni Hartono

“…The incidence recurrence rate is high in trauma Induced RASI, especially in younger patients. The right diagnosis and management must be ruled out immediately for a better outcome. …”
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Practical Aspects of Clinical Manifestations, Pathogenesis and Therapy of Alcoholic Liver Disease and Non-alcoholic Fatty Liver Disease: Expert Opinion by V. V. Tsukanov, M. F. Osipenko, E. V. Beloborodova, M. A. Livzan, I. B. Khlynov, S. A. Alekseenko, Yu. P. Sivolap, J. L. Tonkikh, A. V. Vasyutin

“…ALD and NAFLD are characterized by high prevalence and have a significant impact on public health. For the diagnosis of liver pathology, it is important to determine the stage of fibrosis and the severity of the exacerbation of the disease. …”
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Detection acoustic signals of partial discharges on defects in high voltage insulation by D. A. Ivanov, T. G. Galieva, A. V. Golenishchev-Kutuzov, M. F. Sadykov, R. I. Kalimullin, A. V. Semennikov

“…The ability to detect sources of partial discharges with reference to the place of origin is important for localizing a faulty element and its further diagnosis.…”
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64Cu-chelated InP/ZnSe/ZnS QDs as PET/fluorescence dual-modal probe for tumor imaging by Ziyu Zhao, Ayaka Otsuka, Noriko Nakamura, Toshifumi Tatsumi, Kazuhiro Nakatsui, Taiki Tsuzukiishi, Tomo Sakanoue, Kenji Shimazoe, Seiichi Ohta

“…This novel PET/fluorescence dual-modal probe is expected to contribute to more precise tumor diagnosis.…”
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Colorectal Carcinoma with Extremely Low CA19-9 by Yutaka J. Kawamura, Aika Tokumitsu, Junichi Sasaki, Shingo Tsujinaka, Takafumi Maeda, Ken Mizogami, Fumio Konishi

“…Patients with CA19-9 level of less than 2 U/mL at the time of diagnosis were defined as Extremely Low CA19-9 (ELCA). …”
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Prediction models for cognitive impairment in middle-aged patients with cerebral small vessel disease by Wei Zheng, Xiaoyan Qin, Ronghua Mu, Peng Yang, Bingqin Huang, Bingqin Huang, Zhixuan Song, Xiqi Zhu, Xiqi Zhu

“…The combination model of imaging markers and hippocampal texture did not yield improved a better diagnosis compared to the individual model (p > 0.05).ConclusionThe hippocampal texture model is a surrogate imaging marker for predicting cognitive impairment in middle-aged CSVD patients.…”
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Development and Validation of LAMP Assays for Distinguishing MPXV Clades with Fluorescent and Colorimetric Readouts by Nazente Atceken, Sara Asghari Dilmani, Ahmed Choukri Abdullah, Mutlu Sarıkaya, Defne Yigci, Gozde Korkmaz, Savas Tasoglu

“…As a result, we successfully developed three highly specific molecular diagnostic tests that distinctly differentiate between MPXV clades, delivering essential tools for the precise diagnosis and effective control of Mpox.…”
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Multimodal treatments and the risk of breast cancer-related lymphedema: insights from a nationally representative cohort in South Korea by Sung Hoon Jeong, Seong Min Chun, Miji Kim, Ye Seol Lee, Jisun Kim, Ja-Ho Leigh, Yoon-Hee Choi

“…Methods In this retrospective study conducted using National Health Insurance data and the Korea National Cancer Incidence Database (2006–2017), 114,638 participants who underwent Surgery (Surg) or Chemo within 6 months after breast cancer diagnosis were enrolled, and the effect of multimodality treatment on the risk of BCRL was analyzed using the Cox proportional-hazards model. …”
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China’s national continuing medical education program for general practitioners: a cross-sectional survey (2016–2023) by Conglei You, Lingling Wang, Jian Zhang, Mi Yao

“…Content-based CME evaluations revealed that the teaching focus is the diagnosis, treatment, and primary care management of elderly patients and chronic diseases such as diabetes and hypertension. …”
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A Case of Relapsing Polychondritis Initiating with Unexplained Fever by Kosuke Hirayama, Nozomi Iwanaga, Yasumori Izumi, Satoshi Yoshimura, Kazuhiro Kurohama, Mai Yamashita, Taichi Takahata, Ryuta Oku, Masahiro Ito, Atsushi Kawakami, Kiyoshi Migita

“…In this case, identification of the origin of fever was a challenge because of unspecific symptoms; however, awareness of the systemic manifestations of RP may lead to the prompt diagnosis and therapeutic intervention.…”
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Association between Clinical Characteristics and Laboratory Findings with Outcome of Hospitalized COVID-19 Patients: A Report from Northeast Iran by Sahar Sobhani, Reihaneh Aryan, Elham Kalantari, Salman Soltani, Nafise Malek, Parisa Pirzadeh, Amir Yarahmadi, Atena Aghaee

“…Clinical characteristics, laboratory findings, and their association with the outcome of patients with COVID-19 can be decisive in management and early diagnosis. Data were obtained retrospectively from medical records of 397 hospitalized COVID-19 patients between February and May 2020 in Imam Reza Hospital, northeast Iran. …”
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Bone Mass Loss and Sarcopenia in Ecuadorian Patients by M. Intriago, G. Maldonado, R. Guerrero, O. D. Messina, C. Rios

“…A cross-sectional study was conducted in a population of patients who had a densitometric study. The diagnosis of sarcopenia was determined by the DXA standard gold test, screening, and conventional methods (bioimpedance, anthropometric measurements, SARC-F, muscle function, and gait test). …”
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A Rapidly Enlarging Squamous Inclusion Cyst in an Axillary Lymph Node following Core Needle Biopsy by Cunxian Zhang, Jinjun Xiong, M. Ruhul Quddus, Joyce J. Ou, Katrine Hansen, C. James Sung

“…Our case demonstrates the diagnostic challenges related to a ruptured squamous inclusion cyst and serves to inform the readers to consider this lesion in the differential diagnosis for similar situations.…”
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