Significant room for improvement in the prehospital assessment and treatment of acute abdominal pain: a retrospective observational study by Rasmus Bjerén, Carl Magnusson, Johan Herlitz, Denise Bäckström

“…This is particularly relevant given the long-standing controversy surrounding the use of analgesia in AAP patients before a final diagnosis is made, which may still influence the prehospital pain management. …”
Get full text

circHUWE1 Exerts an Oncogenic Role in Inducing DDP-Resistant NSCLC Progression Depending on the Regulation of miR-34a-5p/TNFAIP8 by Xueliang Yang, Quan Sun, Yongming Song, Wenli Li

“…Conclusion. circHUWE1 functioned as a promoter in DDP-resistant NSCLC by interaction with miR-34a-5p-TNFAIP8 networks, providing novel insight into DDP-resistant NSCLC diagnosis and treatment.…”
Get full text

Point-of-care lung ultrasound in detecting pneumonia: A systematic review by Iqra Abid, Nadia Qureshi, Nicola Lategan, Simon Williams, Sidra Shahid

“…This review aimed to investigate the benefits of point-of-care LUS for the early diagnosis of pneumonia compared to traditional chest X-rays (CXR) in a subgroup analysis including pediatric, adult, and geriatric populations…”
Get full text

Association of Sicca Syndrome with Proviral Load and Proinflammatory Cytokines in HTLV-1 Infection by Clara Mônica Lima, Silvane Santos, Adriana Dourado, Natália B. Carvalho, Valéria Bittencourt, Marcus Miranda Lessa, Isadora Siqueira, Edgar M. Carvalho

“…The Sjögren syndrome has been diagnosed in patients with HTLV-1 associated myelopathy and dry mouth and dry eyes are documented in HTLV-1 carriers. However the diagnosis of Sjögren syndrome in these subjects has been contested. …”
Get full text

Prevalence and predictors of NTM in presumed/confirmed drug-resistant TB by E.T. Abbew, R. Laryea, F. Sorvor, Y.A. Poku, N. Lorent, D. Obiri-Yeboah, L. Lynen, L. Rigouts

“…METHODS: Sputum samples collected for DR-TB diagnosis and follow-up from 2012 to 2021 in Ghana were retrospectively analysed. …”
Get full text

Evaluation of Sacroiliac Joint Shape in Women with Ankylosing Spondylitis According to Mode of Birth Delivery: A Retrospective Study by Sakine Rahimli Ocakoglu, Alper Vatansever, Zeliha Atak, Nurefsan Yanardag, Belkis Nihan Coskun, Sinem Akselim, Gokhan Ocakoglu

“…This suggests that most patients with AS are of reproductive age at the time of diagnosis. The study aimed to identify differences in the shape of the sacroiliac joint depending on the type of birth (vaginal delivery (V/D) and the cesarean section(C/S) in patients with ankylosing spondylitis. …”
Get full text

Retrospective Analysis of RSV Infection in Pediatric Patients: Epidemiology, Comorbidities, Treatment, and Costs in Dubai (2014-2023) by Jean Joury, Nawal Al Kaabi, Sara Al Dallal, Bassam Mahboub, Mostafa Zayed, Mohamed Abdelaziz, Jennifer Onwumeh-Okwundu, Mark A. Fletcher, Subramanyam Kumaresan, Badarinath C. Ramachandrachar, Mohamed Farghaly

“…Patients aged <18 years with a first-episode diagnosis claim (primary or secondary, or a hospital admission) for RSV any time during the index period (Jan. 1, 2014–June 30, 2023) were included. …”
Get full text

Combination of inflammatory proteins in serum can be used to diagnose papillary thyroid carcinoma with lymph node metastasis by Yongqin Pan, Guanghao Wang, Delin Chen, Zhihui Wu, Yimwing Kei, Mingxi Xu

“…Results Five proteins, including IL-22RA1, IL-12B, CCL4, CCL3, and IL-1α, were significantly elevated in the serum of patients with LNM. The combined diagnosis of these five proteins demonstrated excellent diagnostic performance in distinguishing patients with PTC-LNM (area under the curve = 0.967, sensitivity = 0.941, and specificity = 0.889). …”
Get full text

Seasonal Profile and Five-Year Trend Analysis of Malaria Prevalence in Maygaba Health Center, Welkait District, Northwest Ethiopia by Fitsum Tigu, Tsegay Gebremaryam, Asnake Desalegn

“…The study was done on 36,219 outpatients attending for malaria diagnosis during January 2015 to 2019. Data was extracted from the outpatient medical database. …”
Get full text

Clinical Investigation of Benign Asbestos Pleural Effusion by Nobukazu Fujimoto, Kenichi Gemba, Keisuke Aoe, Katsuya Kato, Takako Yokoyama, Ikuji Usami, Kazuo Onishi, Keiichi Mizuhashi, Toshikazu Yusa, Takumi Kishimoto

“…All were males and the median age at diagnosis was 74 years. The median duration of asbestos exposure and period of latency for disease onset of BAPE were 31 and 48 years, respectively. …”
Get full text

Effects of prophylactic antibiotic administration and antibiotic timing on culture results and clinical outcomes of paediatric musculoskeletal infection: a protocol for a randomise... by Chao You, Yibiao Zhou, Zhiyong Liu, Chao Deng, Yongjie Xia, Dechao Wu, Liangfu Xie, Bing E, Jingming Han

“…Individuals aged 0–18 years with a diagnosis of MSI will be screened and evaluated at the Shenzhen Children’s Hospital. …”
Get full text

Six-year performance of risk-based selection for lung cancer screening in the Manchester Lung Health Check cohort by Matthew Sperrin, Haval Balata, Richard Booton, Hilary A Robbins, Philip A J Crosbie, Patrick Goodley

“…The effect of screening on increasing the probability of lung cancer diagnosis should be considered when interpreting measures of prediction model performance.…”
Get full text

The Role of Heart Rate, Body Temperature, and Respiratory Rate in Predicting Anastomotic Leakage following Surgery for Rectal Cancer by Jiajun Luo, Hongxue Wu, Yue Jiang, Yu Yang, Jingwen Yuan, Qiang Tong

“…Observation of postoperative vital signs at 7 days postsurgery is helpful for the early diagnosis of anastomotic leakage.…”
Get full text

Cardiotoxicity of polystyrene nanoplastics and associated mechanism of myocardial cell injury in mice by Ziyi Xiong, Qiling Kong, Juan Hua, Qi Chen, Dandan Wang

“…Conclusions: This study provides new evidence regarding the potential mechanisms of PS-NP cardiovascular toxicity as well as insights into the diagnosis and treatment of unexplained dilated cardiomyopathy in clinical settings.…”
Get full text

From Night to Light: A Bibliometric Analysis of the Global Research Trajectory of Sleep Disorders in Parkinson&rsquo;s Disease by Shi L, Zhao X, Wu J, He C

“…Emerging trends involve comprehensive evaluations of sleep, early diagnosis and prevention of various sleep disorder subtypes in PD, and advancing research through animal models to develop effective therapies. …”
Get full text

A scoping review on the psychosocial interventions used in day care service for people living with dementia. by Dympna Tuohy, Liz Kingston, Eileen Carey, Margaret Graham, Liz Dore, Owen Doody

“…<h4>Background</h4>Adult Day care centres provide an important aspect of care provision through all phases of the dementia illness from diagnosis to the end of life (Dabelko HI 2008) supporting the well-being of both older people living with dementia and their care partners. …”
Get full text

A 23-Year-Old Female with a Mixed Germ Cell Tumor of the Pituitary Infundibulum: The Challenge of Differentiating Neoplasm from Lymphocytic Infundibuloneurohypophysitis—A Case Repo... by Sann Yu Mon, Hussain Mahmud, Munira Abbasi, Geoff Murdoch, Juan C. Fernandez-Miranda, Paul A. Gardner, Sue M. Challinor

“…In our case, biopsy with comprehensive immunohistochemical staining was the sole means of making a definitive diagnosis.…”
Get full text

High-resolution genetic analysis of whole APC gene deletions: a report of two cases and patient characteristics by Hiroki Tanabe, Yasuyuki Koshizuka, Kazuyuki Tanaka, Kenji Takahashi, Masami Ijiri, Keitaro Takahashi, Katsuyoshi Ando, Nobuhiro Ueno, Shin Kashima, Takeo Sarashina, Kentaro Moriichi, Kenrokuro Mitsube, Yusuke Mizukami, Mikihiro Fujiya, Yoshio Makita

“…Abstract Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome caused by germline variants in the APC gene, leading to the development of numerous colorectal polyps and significantly increases the risk of colorectal cancer. A diagnosis is typically made using colonoscopy, and genetic testing can assist in patient surveillance and carrier identification. …”
Get full text

Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study by Songjing Chen, Sizhu Wu

“…The proposed intervention and diagnosis pathways could be used for early screening and intervention before the occurrence of lung cancer, which could help oncologists develop targeted intervention strategies for the stratified elderly to reduce lung cancer incidence and improve therapeutic effect. …”
Get full text

Another way? An investigation into an institution’s use of the Wayson stain in re-evaluating “no organisms seen” on Gram stain smears from positive blood cultures by Christopher C. Attaway, Jessica Smith, Daniel D. Rhoads

“…The Wayson stain aided in detecting gram-negative genera such as Capnocytophaga, Campylobacter, and Fusobacterium species and other rarely identified species.IMPORTANCEThe Wayson stain, a rapid one-step stain that provides contrast between microorganisms and the background, was historically used for the presumptive diagnosis of Yersinia pestis from bubo specimen. In our laboratory, the Wayson stain has long been used to reevaluate blood culture Gram-stained smears from bottles that were flagged as positive by the automated continuous monitoring instrument but where no organisms are seen. …”
Get full text