Clinical Features and Genetic Analysis of 20 Chinese Patients with X-Linked Hyper-IgM Syndrome by Lin-Lin Wang, Wei Zhou, Wei Zhao, Zhi-Qing Tian, Wei-Fan Wang, Xiao-Fang Wang, Tong-Xin Chen

“…Half of them had positive family histories, with a shorter diagnosis lag. The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients, 65%), and protracted diarrhea (13 patients, 65%). …”
Get full text

The Safety and Efficacy of Lansoprazole plus Metoclopramide among Neonates with Gastroesophageal Reflux Disease Resistant to Conservative Therapy and Monotherapy: A Clinical Trial by Peymaneh Alizadeh Taheri, Elahe Validad, Kambiz Eftekhari

“…This study was a randomized clinical trial of term neonates with GERD diagnosis (according to the final version of the I-GERQ-R), resistant to conservative and monotherapy admitted to Bahrami Children Hospital during 2017-2019. …”
Get full text

Primary Fallopian Tube Carcinoma: Results of a Single-Institutional Retrospective Analysis of 17 Patients with Evaluation of Staging and Prognostic Factors by Neserine Tounsi, Hanen Bouazize, Ikram Margheli, Nadia Boujelbene, Hechiche Monia, Maher Slimane, Khaled Rahel

“…RESULTS: The average age at the time of diagnosis was 58 years. Fourteen of the included patients were postmenopausal. …”
Get full text

“What does ‘often’ even mean?” Revising and validating the Comprehensive Autistic Trait Inventory in partnership with autistic people by Friederike Charlotte Hechler, Outi Tuomainen, Nathan Weber, Frank Fahr, Bodie Karlek, Marie Maroske, Meike Misia, Nathan Caruana

“…We validated the CATI-R within a large sample (n = 1439), comprising people with a self-reported autism diagnosis (n = 331), people who self-identified as autistic (n = 44), and non-autistic participants (n = 1046). …”
Get full text

Risk stratification for acute stroke development after a transient ischemic attack and the use of scoring systems in pre-hospital scenarios by Janković Tamara, Đorđević Stefan

“…They aid emergency physicians in correctly recognising the early signs and symptoms, reaching a timely diagnosis, and preventing the development of cerebrovascular insult after TIA. …”
Get full text

Increased Frequency of CD4+ CD25+ FoxP3+ T Regulatory Cells in Pulmonary Tuberculosis Patients Undergoing Specific Treatment and Its Relationship with Their Immune-Endocrine Profil... by Ariana Díaz, Natalia Santucci, Bettina Bongiovanni, Luciano D’Attilio, Claudia Massoni, Susana Lioi, Stella Radcliffe, Griselda Dídoli, Oscar Bottasso, María Luisa Bay

“…Patients were bled at diagnosis (T0) and at 2 (T2), 4 (T4), 6 (T6), and 9 months following treatment initiation. …”
Get full text

Clinical Characteristics and Prognosis of Gastrointestinal Metastases in Solid Tumor Patients: A Retrospective Study and Review of Literatures by Li Lin, Xiangyi Wang, Chuanhao Tang, Jun Liang

“…Patients with gastrointestinal metastases in the setting of stage IV primary carcinomas treated at Beijing Ditan Hospital and Peking University International Hospital from November 1992 to August 2017 were included in this study. The diagnosis of gastrointestinal tract metastases was based on histopathology. …”
Get full text

Current challenges and implications for dengue, chikungunya and Zika seroprevalence studies worldwide: A scoping review. by Camille Fritzell, Dominique Rousset, Antoine Adde, Mirdad Kazanji, Maria D Van Kerkhove, Claude Flamand

“…Moreover, the development of reliable, rapid and affordable diagnosis tools represents a significant issue concerning the ability of seroprevalence surveys to differentiate infections when multiple viruses co-circulate.…”
Get full text

Netarsudil as an Adjunctive Therapy: Efficacy and Factors Contributing to a Favorable IOP-Lowering Effect by Sandy Samuel, Hani El Helwe, Cameron E. Neeson, Nathan Hall, Ryan Sameen Meshkin, Nino Odishelidze, Rebecca Ye, Ta C. Chang, David Solá-Del Valle

“…This is a single-center, multiprovider retrospective cohort study set at Massachusetts Eye and Ear. Patients with a diagnosis of glaucoma or ocular hypertension on netarsudil and at least one other hypotensive agent for glaucoma who had at least one month of follow-up were included. …”
Get full text

Isolation and Evaluation of Clinically Important Acinetobacter Baumannii From Intensive Care Unit Samples by Mohamed Mowfik Sehree, Hanaa N. Abdullah, Amani M. Jasim

“…The current study is at aimed at isolating and identifying the clinical isolates of A. baumannii from different samples and investigating the antibiotic resistance of isolates. Isolation and diagnosis of bacteria were achieved by conventional techniques, including routine and selective culture media (Chrome agar), biochemical test, EPI 20E, and VITEK-2. …”
Get full text

Imaging Hepatocellular Carcinoma With Ga-Citrate PET: First Clinical Experience by Carina Mari Aparici MD, Spencer C. Behr MD, Youngho Seo PhD, R. Kate Kelley MD, Carlos Corvera MD, Kenneth T. Gao, Rahul Aggarwal MD, Michael J. Evans PhD

“…Nuclear imaging tools that can detect molecular subsets of tumors could greatly improve diagnosis and management of HCC. To this end, we conducted a patient study to determine whether HCC can be resolved using 68 Ga-citrate positron emission tomography (PET). …”
Get full text

Prevalence and Imaging Characteristics of Palatine Tonsilloliths Detected by CT in 2,873 Consecutive Patients by Akira Takahashi, Chieko Sugawara, Takaharu Kudoh, Daisuke Uchida, Tetsuya Tamatani, Hirokazu Nagai, Youji Miyamoto

“…As palatine tonsilloliths are common conditions, screenings for tonsilloliths during the diagnosis of soft tissue calcifications should be included in routine diagnostic imaging.…”
Get full text

Urine metabolic profile in rats with arterial hypertension of different genesis by A. A. Sorokoumova, A. A. Seryapina, Yu. K. Polityko, L. V. Yanshole, Yu. P. Tsentalovich, М. А. Gilinsky, А. L. Markel

“…The diversity of pathogenetic mechanisms underlying arterial hypertension leads to the necessity to devise a personalized approach to the diagnosis and treatment of the disease. Metabolomics is one of the promising methods for personalized medicine, as it provides a comprehensive understanding of the physiological processes occurring in the body. …”
Get full text

Impact of HIV on HPV-related cancers in men who have sex with men: a review by Zixuan Zhang, Zixuan Zhang, Yuying Xing, Yuying Xing, Tingdan Gong, Wanlin Li, Siwei Zhang, Lanlan Wei

“…We integrated epidemiological data from the past five years and discussed diagnosis and treatment strategies. Overall, our review offers crucial insights into the underlying molecular and cellular mechanisms of these co-infection MSM patients. …”
Get full text

Enhancing early lung cancer detection with MobileNet: A comprehensive transfer learning approach by Raquel Ochoa-Ornelas, Alberto Gudiño-Ochoa, Julio Alberto García-Rodríguez, Sofia Uribe-Toscano

“…These promising results highlight the potential of MobileNetV2 as a highly effective tool for the early detection of lung cancer, offering substantial support for clinical diagnosis. By facilitating more accurate and timely diagnoses, this approach has the potential to significantly enhance patient care and improve survival rates in lung cancer patients.…”
Get full text

Acute Abdomen as a Clinical Presentation of COVID-19-Associated Multisystem Inflammatory Syndrome in Children by Elmira Hajiesmaeil Memar, Fatemeh Tahghighi, Sedigheh Yousefzadegan, Parisa Sadeghirad, Ashraf Mousavi, Ramin Zare Mahmoudabadi, Hossein Saeidi, Mehri Ayati, Sahar Naderi, Sara Memarian, Seyedmusa Zeinalabedin, Bahar Ashjaei, Hojatollah Raji, Leila Tahernia, Hosein Alimadadi, Vahid Ziaee

“…In six cases, laparotomy or abdominal surgery was performed for a diagnosis of acute abdomen, but appendicitis was confirmed in only one case. …”
Get full text

Multi-sequence MRI-based nomogram for prediction of human epidermal growth factor receptor 2 expression in breast cancer by Mengyi Shen, Li Zhang, Dingyi Zhang, Xin He, Nian Liu, Xiaohua Huang

“…Conclusion: The developed multi-sequence MRI-based nomogram presents a promising tool for predicting HER2 expression, and is expected to improve the diagnosis and treatment of BC.…”
Get full text

BRD8 Guards the Pluripotent State by Sensing and Maintaining Histone Acetylation by Li Sun, Xiuling Fu, Zhen Xiao, Gang Ma, Yibin Zhou, Haoqing Hu, Liyang Shi, Dongwei Li, Ralf Jauch, Andrew Paul Hutchins

Get full text

Evaluation of Hydatid Cyst Cases: A Single-center Retrospective Study by Suzan Şahin, Bülent Kaya

“…Single cases of brain, spinal cord, spleen, kidney, and bone involvement were observed. Diagnosis was made by ultrasonography in 16 patients (53.3%), magnetic resonance imaging in 8 patients (26.7%), and computed tomography in 6 patients (20.0%). …”
Get full text

Implementation outcomes of 1-3-7 focus investigation for malaria in a low transmission setting in Southern Province, Zambia: A mixed methods study. by Anne C Martin, Japhet Matoba, Caison Sing'anga, Mukuma Lubinda, Sydney Mweetwa, Xinyue Chen, Ignatius Banda, Busiku Hamainza, Harry Hamapumbu, Edgar Simulundu, William J Moss, Southern and Central Africa International Centers of Excellence for Malaria Research

“…The 1-3-7 focus investigation approach is an implementation strategy that requires case reporting, case investigation/classification, and focal classification/response to be completed one, three, and seven days, respectively, after index case diagnosis. Real-time short-messaging-service reports are sent at each step to add accountability and data transparency. …”
Get full text