Histogram of Apparent Diffusion Coefficient to Evaluate the Activity of Thyroid‐Associated Ophthalmopathy by Defu Li, Tingting Zhu, Yujin Wang

“…Conclusion ADC histograms provide a new method for distinguishing active from inactive TAO, and the 10th percentile enhances the clinical diagnosis of active TAO. In addition to male sex and smoking, an ADC histogram median > 1.26 μm²/s, entropy > 4.03, or SD > 0.4 may also predict active TAO.…”
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The Clinical Characteristics and Surgical Outcomes of Epiblepharon in Korean Children: A 9-Year Experience by Jong Soo Kim, Sang Wook Jin, Mun Chong Hur, Yoon Hyung Kwon, Won Yeol Ryu, Woo Jin Jeong, Hee Bae Ahn

“…A thorough ocular examination can lead to a correct diagnosis and timely corrective surgery. Most procedures are successful and prevent secondary complications that often occur with uncorrected epiblepharon.…”
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Real-Time Multi-Task Deep Learning Model for Polyp Detection, Characterization, and Size Estimation by Phanukorn Sunthornwetchapong, Kasichon Hombubpha, Kasenee Tiankanon, Satimai Aniwan, Pasit Jakkrawankul, Natawut Nupairoj, Peerapon Vateekul, Rungsun Rerknimitr

“…A proven method for enhancing performance is computer-aided detection and a diagnosis system for endoscopists, which tends to be a real-time system. …”
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Clinical, biochemical and molecular characteristics of classic homocystinuria in Saudi Arabia and the impact of newborn screening on prevention of the complications: A tertiary cen... by Ahmed Sarar Mohamed, Talal AlAnzi, Amal Alhashem, Hadeel Alrukban, Fahad Al Harbi, Sarar Mohamed

“…This study aimed to describe the natural history and the molecular findings of patients with HCU, and to assess the importance of early diagnosis. Methods This study retrospectively collected data on patients attending the metabolic unit at Prince Sultan Military Medical City, Riyadh, Saudi Arabia from 2011 to 2024. …”
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The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…Ccl3 and Lcp1 might potentially modulate IS progression by influencing SASP, proffering novel prospects for IS clinical diagnosis and treatment.…”
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Species specificity and specificity diversity (SSD) framework: a novel method for detecting the unique and enriched species associated with disease by leveraging the microbiome het... by Zhanshan Sam Ma

“…Both capacities can be enabling technologies for general comparative microbiome research including risk assessment, diagnosis, and treatment of microbiome-associated diseases.…”
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Estimating the Burden of Illness Related to Genital Warts in Russia: A Cross-Sectional Study by Vera N. Prilepskaya, Mikhail Gomberg, Smita Kothari, Karen Yee, Amit Kulkarni, Suzanne M. Garland, Anna R. Giuliano

“…Age, gender, and GW diagnosis status was recorded. Prevalence was obtained for each physician and calculated into a single estimate across all physician types. …”
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Optimizing Healthcare Expenditure for Spinal Cord Stimulation in Italy: The Value of Battery Longevity Improvement and a Direct-to-Implant Approach by Federica Tito, Gianfranco Sindaco, Simon Eggington, Elisa Tacconi, Francesca Borghetti, Mara Corbo, Gilberto Pari

“…Costs considered were the initial device implantation procedure, device replacements, and serious adverse event (SAE) management. Italian diagnosis-related group (DRG) tariffs were applied for costs, and a 15-year time horizon was used. …”
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Indian Psychiatric Society multicentre study: Diagnostic patterns, comorbidity and prescription practices for patients with Dementia by CT Sudhir Kumar, Mathew Varghese, Venugopal Duddu, Sridhar Vaitheswaran, Shrikant Srivastava, KS Shaji, Sanju George, Narendra Kumar Singh, Nishant Goyal, Ajay Bakhla, S Shaji, Vikas Menon, Tajamul Hussain, Sandeep Grover, Aseem Mehra, Lokesh Kumar Singh, A Purushotham, Avinash Desousa, Nilesh Shah, Sagar Karia, I Anand, Shafana Afroon, Ritambhara Mehta, Gargi Kukreja, Dimple Dadarwala, KL Vidya, PT Sivakumar, Preeti Sinha, Shivashankar Reddy, Thomas Isaac, Mina Chandra

“…Alzheimer’s disease (349; 59.6%) was the most frequent diagnosis followed by vascular dementia (117; 20%). …”
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First Report of Diabetes Phenotype due to a Loss-of-Function ABCC8 Mutation Previously Known to Cause Congenital Hyperinsulinism by Theocharis Koufakis, Amalia Sertedaki, Elizabeth-Barbara Tatsi, Christina-Maria Trakatelli, Spyridon N. Karras, Eleni Manthou, Christina Kanaka-Gantenbein, Kalliopi Kotsa

“…ABCC8-related diabetes is characterized by remarkable heterogeneity in terms of clinical presentation and therapeutic approach. Early diagnosis and individualized treatment are essential to achieving metabolic targets and avoiding long-term diabetes complications.…”
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Mental health in people living with and beyond colorectal cancer: A patient‐oriented constructivist grounded theory by Vicki Cheng, Helen McTaggart‐Cowan, Jonathan M. Loree, Rachel A. Murphy, Mikaela Barnes, Haydn Bechthold, Norman Jansen, Mary A. De Vera

“…Results Twenty‐eight participants diagnosed with CRC (18 females, 10 males), aged 18–63 years at time of diagnosis were interviewed, with representation across all CRC stages. …”
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Identification of a Fetal De Novo Splice Variant in ARCN1 Associated With Growth and Skeletal Abnormalities by Wencong He, Zejun Yang, Jianjian Cui, Ruilin Ma, Hui Tao, Yanan Li, Yin Zhao, Yang Pan, Jue Li

“…To report a fetus with ARCN1-related syndrome caused by a novel de novo heterozygous variant, highlighting the importance of early genetic diagnosis in prenatal care. Methods:. The clinical and genetic data of a fetus with a complex combination of clinical signs and a novel de novo heterozygous variant were collected and have been summarized in this study. …”
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First Account of Primary Leiomyosarcoma of the Lesser Omentum since Establishment of c-Kit Mutations in Gastrointestinal Stromal Tumors by Fumito Saijo, Kaoru Sato, Tomoko Handa, Yoichi Narushima, Naoki Matsumura, Noriyuki Iwama, Fumie Nakayama, Hiromi Tokumura

“…Leiomyosarcomas originating from the lesser omentum have not been reported since immunohistochemical staining for c-kit has been used for the diagnosis of mesenchymal abdominal tumors. They are yet to be reported since gastrointestinal stromal tumors were categorized. …”
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Posterior reversible encephalopathy syndrome in a young male with IgA nephropathy and chronic kidney disease: a case report from the Maldives by Rajib Kumar Dey, Gunjan Khadka, Shifa Ishaq, Aishath Zeena Abdul Jaleel, Aminath Shafeenaz Moosa, Saifullah Muslim, Ali Nazeem

“…Clinical suspicion and radiological findings aid in early diagnosis. It is also important to be aware of uncommon radiological findings (involvement of the right frontal periventricular area) as in our case.…”
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The Burden of NAFLD and Its Characteristics in a Nationwide Population with Type 2 Diabetes by Gabriele Forlani, Carlo Giorda, Roberta Manti, Natalia Mazzella, Salvatore De Cosmo, Maria Chiara Rossi, Antonio Nicolucci, Paolo Di Bartolo, Antonio Ceriello, Pietro Guida, AMD-Annals Study Group

“…After exclusion of 5967 cases (high or uncertain alcohol intake), in 38,880 the Fatty Liver Index (FLI) was used as a proxy for the diagnosis of NAFLD. Factors associated with FLI assessed NAFLD (FLI-NAFLD) were evaluated through multivariate analysis. …”
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Drawing-Aware Parkinson’s Disease Detection Through Hierarchical Deep Learning Models by Ioannis Kansizoglou, Konstantinos A. Tsintotas, Daniel Bratanov, Antonios Gasteratos

“…Early detection and diagnosis are vital for appropriate treatment through medication and/or occupational therapy, ensuring patients can lead productive and healthy lives. …”
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Expression of Angiogenesis Regulatory Proteins and Epithelial-Mesenchymal Transition Factors in Platelets of the Breast Cancer Patients by Hui Han, Fang-Li Cao, Bao-Zhong Wang, Xue-Ru Mu, Guang-Yao Li, Xiu-Wen Wang

“…Circulating platelets in breast cancer sequester higher levels of PF4, VEGF, PDGF-BB, and TGF-β1, suggesting a possible target for early diagnosis. VEGF, PDGF, and TGF-β1 concentrations in platelets may be associated with prognosis.…”
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Clinical Profile and Visual Outcome of Ocular Bartonellosis in Malaysia by Chai Lee Tan, Lai Chan Fhun, Evelyn Li Min Tai, Nor Hasnida Abdul Gani, Julieana Muhammed, Tengku Norina Tuan Jaafar, Liza Sharmini Ahmad Tajudin, Wan-Hazabbah Wan Hitam

“…This was a retrospective review of patients treated for ocular bartonellosis in two ophthalmology centers in Malaysia between January 2013 and December 2015. The diagnosis was based on clinical features, supported by a positive Bartonella spp. serology. …”
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Genetics of Primary Adrenal Insufficiency Beyond CAH in Saudi Arabian Population by Mohamed H. Al‐Hamed, Alya Qari, Lamya Alrayes, Mohammed Alotaibi, Zainab Al Masseri, Afaf Alotaibi, Abdullah AlAshwal, Zuhair N. AlHassnan, Afaf Alsagheir

“…ABSTRACT Background The use of exome sequencing (ES) has helped in detecting many variants and genes that cause primary adrenal insufficiency (PAI). The diagnosis of PAI is difficult and can be life‐threatening if not treated urgently. …”
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Current Approach of Functioning Head and Neck Paragangliomas: Case Report of a Young Patient with Multiple Asynchronous Tumors by Alejandro Terrones-Lozano, Alan Hernández-Hernández, Edgar Nathal Vera, Gerardo Yoshiaki Guinto-Nishimura, Jorge Luis Balderrama-Bañares, Claudia Ramírez-Rentería, Judith de la Serna-Soto, Alfredo Adolfo Reza-Albarran, Lesly Portocarrero-Ortiz

“…A 33-year-old man with a past medical history of resection of an abdominal PGL at the age of eleven underwent a CT scan after a mild traumatic brain injury revealing an incidental brain tumor. The diagnosis of a functioning PGL was made, and further testing was undertaken with a PET-CT with 68Ga-DOTATATE, SPECT-CT 131-MIBG, and genetic testing. …”
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