Tumor-Induced Osteomalacia: Increased Level of FGF-23 in a Patient with a Phosphaturic Mesenchymal Tumor at the Tibia Expressing Periostin by Anke H. Hautmann, Josef Schroeder, Peter Wild, Matthias G. Hautmann, Elisabeth Huber, Patrick Hoffstetter, Martin Fleck, Christiane Girlich

“…FGF-23 levels were significantly increased, and total body magnetic resonance imaging (MRI) revealed a tumor mass located at the distal tibia leading to the diagnosis of tumor-induced osteomalacia (TIO). After resection of the tumor, hypophosphatemia and the increased levels of FGF-23 normalized within a few days. …”
Get full text

Parents’ views and experiences of raising babies born with cleft lip and palate: a qualitative study by Delaram Alinezhad, Farnoosh Mohammadi, Mohammad Javad Kharazifared, Mahdia Gholami, Sarvin Sarmadi, Samaneh Razeghi

“…Results From 20 interviews, six themes were identified. The diagnosis theme was associated with timing. Key concerns within the psychosocial experiences theme included initial reactions, pressure from society, the child’s future in the community, hiding from family, feeling guilty about the anomaly, and couples’ relationships. …”
Get full text

Determination of reproductive properties of virulent and vaccine classical swine fever virus strains in primary and continuous cell cultures by I. S. Kolbin, A. S. Igolkin, V. L. Gavrilova, O. S. Puzankova, Ye. V. Aronova, A. A. Yelsukova, N. N. Vlasova

“…Hence, the disease surveillance and eradication require highly sensitive methods for early diagnosis of the infection and for tests for the virus circulation in the environment.  …”
Get full text

Development of polymerase chain reaction kit for detection of SARS-CoV-2 RNA in biological samples collected from animals by A. M. Timina, A. S. Yakovleva, M. V. Timanov, M. V. Biryuchenkova, Ye. S. Orlova

“…Today the key methodofCOVID-19 diagnosis is polymerase chain reaction, butall currently availabletest-kits are intended for the virus detection in humans. …”
Get full text

Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma by Gorkem Odabas, Metin Cetin, Serdar Turhal, Huseyin Baloglu, A. Emre Sayan, Tamer Yagci

“…There is still room for novel markers to improve the diagnosis and monitoring of HCC. Our observations in cancer databases that PLXNC1 is upregulated in HCC led us to investigate the expression profile of Plexin C1 mRNA and protein in HCC cell lines and tissues. …”
Get full text

Sinusoidal Obstruction Syndrome (SOS) in Multiple Myeloma with Renal Failure by Urvi A. Shah, Sengottuvel Viswanathan, Beamon Agarwal, Aditi Shastri, Ioannis Mantzaris, Murali Janakiram, Noah Kornblum, Ira Braunschweig, Amit Verma, Yang Shi, John Reinus, Olga Derman

“…With the recent FDA approval of defibrotide in 2016, outcomes of SOS have improved and physician awareness is important for prompt diagnosis and treatment.…”
Get full text

Assessing ECG Interpretation Expertise in Medical Practitioners Through Eye Movement Data and Neuromorphic Models by Syed Mohsin Bokhari, Muhammad Shafi, Fazal Noor, Sarmad Sohaib, Saad Alqahtany, Mark Donnelly

“…This paradigm has the potential to construct skill evaluation tools in medical education, specifically for ECG interpretation training, thereby addressing prevalent difficulties related to inconsistent ECG diagnosis methods.…”
Get full text

How May Coexisting Frailty Influence Adherence to Treatment in Elderly Hypertensive Patients? by Bartosz Uchmanowicz, Anna Chudiak, Izabella Uchmanowicz, Grzegorz Mazur

“…The coexistence of frailty syndrome has a negative impact on the compliance of older patients with hypertension. Diagnosis of frailty and of the associated difficulties in adhering to treatment may allow for targeting the older patients with a poorer prognosis and at risk of complications from untreated or undertreated hypertension and for planning interventions to improve hypertension control.…”
Get full text

Characteristics and Clinical Course of Patients with Acute Myocardial Infarction and ST-segment Elevation with and without Interatrial Block by Francisco de Jesús Valladares Carvajal, Verónica Mercedes Carretero Acosta, Raimundo Carmona Puerta, Aymara Marcia Hernández Cardoso, Ernesto Julio Bernal Valladares

“…Gustavo Aldereguía Lima University General Hospital in Cienfuegos. 169 subjects with a diagnosis of ST-segment elevation myocardial infarction divided into two groups with and without interatrial block were selected. …”
Get full text

Relevance of Invasive Testing in Era of Non-Invasive Testing for Prenatal Chromosomal Abnormalities by Abhijeet Kumar, Madhusudan Dey, Devendra Arora

“… Prenatal screening for chromosomal abnormalities has two components i.e. prenatal screening (maternal serum screening and cell-free fetal DNA screening) and prenatal diagnosis (chorionic villus sampling, amniocentesis, and cordocentesis). …”
Get full text

Clinical characteristics and surgical outcomes in thoracic outlet syndrome: a comparative study of cases with and without cervical rib by Amr N. Ali, Hesham ElSobky, El-Sayed Abou El-Magd, Abdel Wahab Mahmoud Ibrahim

“…Surgical management offers superior outcomes in this subgroup, emphasizing the importance of early diagnosis and intervention. Further studies with larger cohorts are needed to validate these findings and refine management guidelines.…”
Get full text

Occupational Therapy for People with Early Parkinson’s Disease: A Retrospective Program Evaluation by Alan Sadural, Jillian MacDonald, Joelle Johnson, Kavita Gohil, Miriam Rafferty

“…Most individuals (n = 16, 69.6%) were within Hoehn and Yahr stages 1-2 and were seen within 3 years of PD diagnosis. Participants presented with deficits in hand strength (60.0 ± 23.4 pounds) and dexterity (right hand 30.0 ± 8.0 seconds) and reported complaints about basic and/or instrumental activities of daily living (n = 15, 65.2%). …”
Get full text

Circulating Free RNA as a Therapeutic Evaluation in Diffuse Large B-cell Lymphoma: A Case Series from the Indonesian Cancer Center by Noorwati Sutandyo, Ikhwan Rinaldi, Lyana Setiawan, Christine Sugiarto, Yuniar Harris Prayitno

“…Despite advances in diagnosis, management with the rituximab, cyclophosphamide, doxorubicin hydrochloride, vincristine sulfate, and prednisone (R-CHOP) chemotherapy regimen, and careful clinical and radiologic evaluation, diffuse large B-cell lymphoma (DLBCL) still carries high recurrence in clinical practice. …”
Get full text

The Use of Iliac Stem Prosthesis for Acetabular Defects following Resections for Periacetabular Tumors by Massimiliano De Paolis, Alessio Biazzo, Carlo Romagnoli, Nikolin Alì, Sandro Giannini, Davide Maria Donati

“…Between 1999 and 2012, 45 patients underwent pelvic resections for periacetabular bone tumors followed by reconstruction with stem cup prosthesis. The most common diagnosis was CS (chondrosarcoma, 29 cases), followed by OS (osteosarcoma, 9 cases) and metastasis (3 cases). …”
Get full text

Sempervirine inhibits proliferation, invasion and metastasis of ovarian cancer cells and induces ultrastructural changes in vivo by Danni Chen, Yan Tan, Tingting Chen, Qin Wang, Yan Yan, Xiaoya Zhao, Zhongxiao Zhang, Jin Qiu, Jian Zhang

“…Abstract Ovarian cancer is one of the deadliest gynecological malignancies due to its late diagnosis and easy recurrence. Therefore, it is urgent to develop novel therapeutics for ovarian cancer treatment. …”
Get full text

Characterization of Ischemic Cerebrovascular Disease in Diabetic Patients at the General Calixto García Clinical Surgical University Hospital by Yunier Angarica Aguilar, Jorge Félix Salazar Rodríguez, Damaris Herrera Arrebato, Emelina Despaigne Carrión, María de los Ángeles Hechevarría Heredia, César Emilio Reina Rodríguez

“…<br /><strong>Method:</strong> a descriptive study was carried out in diabetic patients who were admitted to the Calixto García Hospital with a diagnosis of acute ischemic cerebrovascular disease in the period between January and December 2022. …”
Get full text

College of American Pathologists (CAP)/American College of Medical Genetics and Genomics (ACMG) proficiency testing for urinary glycosaminoglycan analysis: A summary of performance by Kristina Cusmano-Ozog, Dietrich Matern, Thomas Long, Nicola Longo, Sarah Young

“…Purpose: Glycosaminoglycans (GAGs) accumulate in patients with mucopolysaccharidoses (MPS), multiple sulfatase deficiency, and mucolipidoses; measurement of total GAGs and the specific excretion pattern by fractionation can aid in their diagnosis. Since 1993, the College of American Pathologists with the American College of Medical Genetics and Genomics has offered proficiency testing (PT) for urine GAG analysis accessible to laboratories worldwide. …”
Get full text

Based on network pharmacology and molecular docking to study the mechanisms of active ingredients of ginseng in the treatment of atopic dermatitis by BU Jialiang, SHEN Lin, MENG Yuan, PIAO Yingshi

Get full text

Immunocompatibility of Bacteriophages as Nanomedicines by Tranum Kaur, Nafiseh Nafissi, Olla Wasfi, Katlyn Sheldon, Shawn Wettig, Roderick Slavcev

“…Two potential medical applications of phages are the treatment of bacterial infections and their use as immunizing agents in diagnosis and monitoring patients with immunodeficiencies. …”
Get full text

Attitudes Regarding the Use of Ventilator Support Given a Supposed Terminal Condition among Community-Dwelling Mexican American and Non-Hispanic White Older Adults: A Pilot Study by M. Rosina Finley, Johanna Becho, R. Lillianne Macias, Robert C. Wood, Arthur E. Hernandez, David V. Espino

“…To determine the factors that are associated with Mexican Americans’ preference for ventilator support, given a supposed terminal diagnosis. Methods. 100 Mexican Americans, aged 60–89, were recruited and screened for MMSE scores above 18. …”
Get full text