Inflammation-Related Mechanisms in Chronic Kidney Disease Prediction, Progression, and Outcome by Simona Mihai, Elena Codrici, Ionela Daniela Popescu, Ana-Maria Enciu, Lucian Albulescu, Laura Georgiana Necula, Cristina Mambet, Gabriela Anton, Cristiana Tanase

“…Recent omics advances could provide novel insights in deciphering the disease pathophysiology; thus, identification of circulating biomarker panels using state-of-the-art proteomic technologies could improve CKD early diagnosis, monitoring, and prognostics. This review aims to summarize the recent knowledge regarding the relationship between inflammation and CKD, highlighting the current proteomic approaches, as well as the inflammasomes and gut microbiota dysbiosis involvement in the setting of CKD, culminating with the troubling bidirectional connection between CKD and renal malignancy, raised on the background of an inflammatory condition.…”
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Switched CMOS current source compared to enhanced Howland circuit for bio-impedance applications by da Silva Pablo Dutra, Filho Pedro Bertemes

“…Bio-impedance Spectroscopy (BIS) is a technique that allows tissue analysis to diagnose a variety of diseases, such as medical imaging, cancer diagnosis, muscle fatigue detection, glucose measurement, and others under research. …”
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Primary Nocardia Infection Causing a Fluorodeoxyglucose-Avid Right Renal Mass in a Redo Lung Transplant Recipient by Sreeja Biswas Roy, Mitchell D. Ross, Pradnya D. Patil, Richard Trepeta, Ross M. Bremner, Tanmay S. Panchabhai

“…Special stains confirmed a diagnosis of Nocardia renal abscess. Computed tomography of the chest and brain revealed no lesions consistent with infection. …”
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Generation of microdissected DNA probes from metaphase chromosomes when chromosome identification by routine staining is impossible by K. S. Zadesenets, N. B. Rubtsov

“…Application of microdissected DNA libraries and DNA probes in numerous and various modern molecular cytogenetic studies showed them as an efficient and reliable tool in the analysis of chromosome reorganization during karyotypic evolution and in the diagnosis of human chromosome pathology. An important advantage of DNA probe generation by metaphase chromosome microdissection followed by sequence-independent polymerase chain reaction in comparison with the method of DNA probe generation using chromosome sorting is the possibility of DNA probe preparation from chromosomes of an individual sample without cell line establishment for the production of a large number of metaphase chromosomes. …”
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Co-occurrence of a Mullerian anomaly and Kallmann syndrome: A case report by Lea C. George, Rebecca Gendelman, Anat Chemerinski, Pierre Lespinasse, Inessa A. Goldman, Sara Morelli

“…A thorough endocrine, genetic, and anatomic evaluation is imperative prior to confirming the diagnosis and initiating treatment. Kallmann syndrome has rarely been reported with Mullerian anomalies; in this case it represents a scenario in which the induction of puberty and menses brought an obstructive anomaly to light. …”
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Decline in Memory, Visuospatial Ability, and Crystalized Cognitive Abilities in Older Adults: Normative Aging or Terminal Decline? by R. Bendayan, A. M. Piccinin, S. M. Hofer, D. Cadar, B. Johansson, G. Muniz-Terrera

“…Moreover, the association with individual characteristics as sex, education, and dementia diagnosis was also examined. Measures of cognitive status (Mini-Mental State Examination and the Swedish Clock Test) and tests of crystallized (knowledge and synonyms), memory (verbal memory, nonverbal long-term memory, recognition and correspondence, and short-term memory), and visuospatial ability were included. …”
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Comparison evaluation of bacterial DNA extraction methods for improved molecular diagnostic accuracy of sepsis-causing pathogens in clinical whole blood samples by Byungjoon Na, Junghun Park, Sojin Park, Eunseon Park, Jimin Jang, Yu-Hee Kim, Jinyeop Lee, Hae-Sun Chung

“…Such methods may enable the more rapid and accurate diagnosis of bloodstream infections, potentially improving patient outcomes.…”
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Composite Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma and T-Prolymphocytic Leukemia Presenting with Lymphocytosis, Skin Lesions, and Generalized Lymphadenopathy by Ali Sakhdari, Guilin Tang, Lawrence E. Ginsberg, Cheryl F. Hirsch-Ginsberg, Carlos E. Bueso-Ramos, L. Jeffrey Medeiros, Roberto N. Miranda

“…After 2 years, the T-PLL component became more apparent with cutaneous and hematologic manifestations and the diagnosis was confirmed by immunophenotypic and cytogenetic analysis. …”
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Bacterial extracellular vesicles in the initiation, progression and treatment of atherosclerosis by Yuling Lin, Jingyu Wang, Fan Bu, Ruyi Zhang, Junhui Wang, Yubing Wang, Mei Huang, Yiyi Huang, Lei Zheng, Qian Wang, Xiumei Hu

“…Finally, we discuss the benefits and challenges of using BEVs in atherosclerosis diagnosis and treatment, and propose future research directions to address these issues.…”
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Ultrasound evaluation of gallbladder wall thickness for predicting severe dengue: a systematic review and meta-analysis by Amirhossein Shahsavand Davoudi, Hamid Harandi, Reza Samiee, Shayan Forghani, Keyhan Mohammadi, Maryam Shafaati

“…However, the possibility of differential diagnosis requires cautious interpretation.…”
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Comparison of Atrial Fibrillation in the Young versus That in the Elderly: A Review by Rajiv Sankaranarayanan, Graeme Kirkwood, Katharine Dibb, Clifford J. Garratt

“…Moreover with availability of improved and modern investigational and diagnostic techniques, novel causes of AF are being reported thereby seemingly consigning the diagnosis of “lone AF” to a rather mythical existence. …”
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BioFire FilmArray Blood Culture Identification (BCID) Panel and Clinical Usefulness: A Systematic Review by Niti Gor, Devesh Joshi

“…Introduction: In the critical care of septic patients, timely and accurate diagnosis is paramount. Molecular diagnostic studies that offer rapid and precise results are lacking. …”
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Migratory Fish Bone in the Thyroid Gland: Case Report and Literature Review by EnHao Wu, Lei Huang, Ya Zhou, Xun Zhu

“…Combined with the history should be a wary fish bone to migrate to the case of the thyroid, to avoid misdiagnosis. To confirm the diagnosis, we can take ultrasound, computerized tomographic scanning (CT), and other tests.…”
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Midline Anterior Neck Inclusion Cyst in a Pediatric Patient: A Case Report and Literature Review with a Dermatologic Perspective by Noemi Brigenti, Rachele Bardelli, Giovanni Paolino, Elisabetta Danese, Paolo Gisondi, Nicola Zerbinati, Giampiero Girolomoni, Andrea Carugno

“…Clinical, dermoscopic, and ultrasound evaluations confirmed the diagnosis of MANIC. Over six months of observation, the lesion remained stable without growth, infection, or symptoms. …”
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Рerioperative period of high-risk patients with coronary artery disease by O.K. Gogayeva

“…Careful preoperative diagnosis, preparation, risk stratification, determination of the term of surgery, choice of CABG method taking into account the anthropometric data, the state of the lower extremities veins, anatomical location of coronary arteries, their diameter and degree of damage, personalized drug therapy, allows to achieve good results with minimal complications.…”
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Molecular cloning of EZH2 oncogene in chronic myeloid leukemia and therapeutic prospects by Juliana Costa Gaspar, Lucas Santos de Santana, Camila Menezes Freire de Souza, Marcos Montani Caseiro, Rosane Rezende de Souza Giuliani, Cleide Barbieri de Souza

“…Chronic myeloid leukemia (CML) is a myeloproliferative neoplasia, caused in 95 % of the cases by a cytogenetic abnormality characterized by the reciprocal translocation between chromosomes 9 and 22 t(9; 22) (q34; q11), resulting in Philadelphia chromosome (Ph).Considering that CML cure is only possible with a successful bone marrow transplantation and that there are resistance cases to the tyrosine kinase inhibitor Imatinib Mesylate, prescribed in first line drug treatment; it is important to know in detail the genes and proteins that are possibly altered in CML, favoring effective therapeutic strategies, optimized diagnosis and minimal residual disease detection. Among the new therapeutic approaches to CML is gene therapy, which, depending on the target gene, can be efficient to other neoplasms treatment. …”
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Proteomic Profiling Towards a Better Understanding of Genetic Based Muscular Diseases: The Current Picture and a Look to the Future by Marc Pauper, Andreas Hentschel, Malte Tiburcy, Sergi Beltran, Tobias Ruck, Ulrike Schara-Schmidt, Andreas Roos

“…Proteomics accelerates diagnosis and research of muscular diseases by enabling the robust analysis of proteins relevant for the manifestation of neuromuscular diseases in the following aspects: (i) evaluation of the effect of genetic variants on the corresponding protein, (ii) prediction of the underlying genetic defect based on the proteomic signature of muscle biopsies, (iii) analysis of pathophysiologies underlying different entities of muscular diseases, key for the definition of new intervention concepts, and (iv) patient stratification according to biochemical fingerprints as well as (v) monitoring the success of therapeutic interventions. …”
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Seronegative Intestinal Villous Atrophy: A Diagnostic Challenge by Cláudio Martins, Cristina Teixeira, Suzane Ribeiro, Daniel Trabulo, Cláudia Cardoso, João Mangualde, Ricardo Freire, Ana Luísa Alves, Élia Gamito, Isabelle Cremers, Ana Paula Oliveira

“…In these cases, before establishing the diagnosis of seronegative celiac disease, alternative etiologies of atrophic enteropathy should be considered. …”
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Anaesthetic Management of a Neonate with Ebstein’s Anomaly Undergoing a Meningomyelocele Surgery: A Case Report by Prakriti, Monika Yadav, Vaishali Gupta, Komal Yadav, Shikha Garg

“…An Electrocardiogram (ECG) showed supraventricular tachycardia, and a chest X-ray revealed cardiomegaly. The diagnosis of EA was confirmed by two-dimensional (2D) echocardiography. …”
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Towards culturally inclusive healthcare in Peru: Mapping epistemic concepts in contemporary Indigenous Amazonian medicine-Traditional healers' perspectives. by Ilana Berlowitz, Maria Amalia Pesantes, Cynthia Cárdenas Palacios, Chantal Martin-Soelch, Ursula Wolf, Caroline Maake

“…Indigenous healers described multifactorial aetiology concepts, complex interactions between material and spirit-related aspects of body and nature, diagnosis, and treatment. These often involved carefully designed applications of 'teacher plants', a concept at the heart of this medical system. …”
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