The Change of Skeletal Muscle Caused by Inflammation in Obesity as the Key Path to Fibrosis: Thoughts on Mechanisms and Intervention Strategies by Yixuan Li, Wenwen Guo, Han Li, Yuhao Wang, Xinwei Liu, Wen Kong

“…This article provides insight into the important roles of inflammation and fibrosis in the treatment of obesity and the management of skeletal muscle diseases, aiming to provide new ideas for the diagnosis and treatment of metabolic diseases such as obesity and IR.…”
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Laser Capture Microdissection in Dentistry by Uraiwan Chokechanachaisakul, Tomoatsu Kaneko, Takashi Okiji, Reika Kaneko, Hideaki Suda, Jacques E. Nör

“…Thus, the advance of immuno-LCM method allows us to improve the validity of molecular biological analysis and to get more accurate diagnosis in pathological field in contrast to conventional LCM. …”
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The role of optical coherence tomography angiography in assessing diabetic choroidopathy: a systematic review by M. Hossein Nowroozzadeh, Mansoureh Bagheri

“…While advances in imaging technology, particularly optical coherence tomography angiography (OCTA), provide new opportunities to assess choroidal changes in diabetic patients, the role of OCTA in early diagnosis and monitoring of diabetic choroidopathy remains unclear. …”
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Thirteen-Year Follow-Up of a Patient with Liver Cirrhosis Resulting from the Overlap Syndrome of Autoimmune Hepatitis and Primary Biliary Cholangitis: Severe COVID-19 and Liver Tra... by A. Kh. Odintsova, D. R. Akberova, L. R. Sadykova, N. A. Cheremina, M. M. Minnullin, A. A. Kirshin, E. N. Gabitova, A. Yu. Khasanshina, D. I. Abdulganieva

“…Aim: to present the difficulties of long-term management of a patient with liver cirrhosis in the outcome of overlap syndrome (autoimmune hepatitis and primary biliary cholangitis) who suffered from severe COVID-19 infection.Key points. The diagnosis of liver cirrhosis as an outcome of overlap syndrome (autoimmune hepatitis and primary biliary cholangitis) was established at the patient’s age of 33 years. …”
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A study on the production of extracellular vesicles derived from novel immortalized human placental mesenchymal stromal cells by Yingying Tong, Jie Sun, Xin Jiang, Xu Jia, Huimin Xiao, Hua Wang, Guanghua Yang

“…Our findings indicate that the immortalization process preserves the particle size, quantity and surface marker profiles of EVs, providing a possible approach to produce high-yield EVs suitable for disease diagnosis and treatment.…”
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Chronic Benign Tubular Albuminuria From Compound Heterozygous Variants in : A Case Report by Adam Pietrobon, Mark D. Elliott

“…Interventions: Neither angiotensin-converting enzyme (ACE) inhibition nor angiotensin Type II (AT-II) receptor blockade reduced his degree of albuminuria. Diagnosis: Genetic testing identified 3 distinct pathogenic variants in CUBN that were confirmed by segregation analysis to be a compound heterozygous mode of inheritance. …”
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Keratoacanthoma of the Nasal Septum Secondary to Ranibizumab Use by Jason E. Cohn, Hilary M. Caruso Sales, Giang Huong Nguyen, Harvey Spector, Kenneth Briskin

“…Histologic examination revealed a well-circumscribed, dome-shaped central crater filled with keratin, well-differentiated squamous epithelium with ground-glass cytoplasm with pushing margins, and intraepithelial microabscesses establishing the diagnosis of KA. KA of the nasal septum has only been reported once in the literature. …”
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Rift Valley Fever in Rwanda Is Urging for Enhancing Global Health Security Through Multisectoral One Health Strategy by Claude Mambo Muvunyi, Jean Claude Semuto Ngabonziza, Emmanuel Edwar Siddig, Ayman Ahmed

“…This underscores the urgent need for prospective research to inform evidence-based health policymaking, strategic planning, and the development and implementation of cost-effective preventive and control measures, including diagnosis and surveillance for early detection and response. …”
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Managing Chronic Neuropathic Pain: Recent Advances and New Challenges by Namrata Hange, Sujan Poudel, Saleha Ozair, Trissa Paul, Meghna Nambakkam, Rakchhya Shrestha, Farrah Greye, Sangam Shah, Yagya Raj Adhikari, Sangharsha Thapa, Pooja Patel

“…Despite the recent advances in diagnosis and treatment modalities, several challenges still exist. …”
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Diabetic Muscle Infarction Masquerading as Necrotizing Fasciitis by Kalyana C. Janga, Ankur Sinha, Perry Wengrofsky, Phone Oo, Sheldon Greenberg, Regina Tarkovsky, Kavita Sharma

“…A CT guided biopsy of the right quadriceps muscle revealed fibrotic interstitial connective tissue and no evidence of necrosis. This favored a diagnosis of diabetic muscle infarction. The disease was managed with pain control, strict diabetes management, and aggressive dialysis.…”
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Subacute Thyroiditis: Clinical Presentation and Long Term Outcome by Assim A. Alfadda, Reem M. Sallam, Ghadi E. Elawad, Hisham AlDhukair, Mossaed M. Alyahya

“…Only 25 patients had confirmed diagnosis of thyroiditis. Age and gender distribution were similar to other studies. …”
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Knowledge and Attitudes of the Inhabitants of a Rural Canton about the Prevention of Colorectal Cancer by Carlos David Castañeda Guillot, Blanca Cristina Estrella López, Diego Fernando Vaca Sánchez

“…<br /><strong>Results:</strong> a large proportion of respondents were aware that early diagnosis of colorectal cancer increases the chances of cure, however, half of respondents knew that this type of cancer can develop without presenting symptoms. …”
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Study of some virulence genes from uropathogenic Klebsiella pneumoniae and Pseudomonas aeruginosa isolated in Wasit Province, Iraq by Rana H. Raheema, Sabaa Hilal Hadi, Zainab Adil Ghani Chabuck

“…By using molecular techniques, including the 16S rRNA gene, for confirmation of the diagnosis. These findings were validated by the polymerase chain reaction method used to detect the virulence genes fimH gene, where 4/16 (25%) and mrkA gene, where result 7/16 (43.75%) were positive in recovered K. pneumoniae isolated. …”
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Efficacy and safety assessment of propranolol tablets vs. oral solution for infantile hemangioma: a retrospective study in China by Wenting Chen, Hua Qian, Qi Sun, Shan Zhang, Lei Zhu, Yafen Wu, Yingying Qian, Bingbing Wang, Wei Li

“…The propranolol oral solution was not used in China until 2022.ObjectiveTo evaluate the efficacy and safety of propranolol tablets and an oral solution in infants with high-risk IH.MethodsA retrospective cohort study was conducted involving 234 consecutive patients with a clinical diagnosis of high-risk IH who were treated with propranolol between August 2018 and February 2023 (propranolol tablets, 168 patients; propranolol oral solution, 66 patients). …”
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Optic Chiasmitis as an Isolated Manifestation of Myelin Oligodendrocyte Glycoprotein-Associated Disease – a Case Report by Nina Barankiewicz-Tyc, Karolina Kania, Wojciech Kozubski

“…Optic chiasmitis is not a diagnosis in itself, but a sign of an underlying pathology, and during its evaluation should be treated as a variation of atypical optic neuritis. …”
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Diagnostic Value of Dynamic Contrast-Enhanced Magnetic Resonance Imaging in the Evaluation of the Biliary Obstruction by Mehmet Bilgin, Hüseyin Toprak, Mehmet Burgazli, S. Sennur Bilgin, Ritvan Chasan, Ali Erdogan, Cem Balci

“…MRI/MRCP findings compared with final diagnoses, MRI/MRCP in the demonstration of bile duct obstruction sensitivity 96%, the specificity 100%, and accuracy 96.3%, in the detection of presence and level of obstruction, the sensitivity 96.7%, specificity 100%, and accuracy 97.2%, in the diagnosis of choledocholithiasis, the sensitivity 82.3%, specificity 96%, and accuracy 91.7%, and in the determination of the character of the stenosis, sensitivity 95.6%, specificity 91.3%, and accuracy 94.5% were found. …”
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Automated karyogram analysis for early detection of genetic and neurodegenerative disorders: a hybrid machine learning approach by Sumaira Tabassum, M. Jawad Khan, Javaid Iqbal, Asim Waris, M. Adeel Ijaz

“…This automated model has the potential to significantly contribute to the early detection and diagnosis of chromosome-related disorders that affect both genetic health and neurological behavior.…”
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Automatic Detection of Small Intestinal Hookworms in Capsule Endoscopy Images Based on a Convolutional Neural Network by Tao Gan, Yulin Yang, Shuaicheng Liu, Bing Zeng, Jinlin Yang, Kai Deng, Junchao Wu, Li Yang

“…This trial is registered with ChiCTR2000034546 (a clinical research of artificial-intelligence-aided diagnosis for hookworms in small intestine by capsule endoscope images).…”
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Characteristics of Invasive Pulmonary Fungal Diseases Diagnosed by Pathological Examination by Dong Zhang, Xin Li, Junquan Zhang, Junping Wu, Xin Sun

“…Pathological examination with fungal stains has its advantages in diagnosing fungal disease; therefore, more attention should be paid to the role of pathological examination in the diagnosis of fungal disease.…”
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Theoretical and Experimental Study of an Electrokinetic Micromanipulator for Biological Applications by Reza Hadjiaghaie Vafaie, Ali Fardi-Ilkhchy, Sobhan Sheykhivand, Sebelan Danishvar

“…The ability to control and manipulate biological fluids within microchannels is a fundamental challenge in biological diagnosis and pharmaceutical analyses, particularly when buffers with very high ionic strength are used. …”
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