Genetic Variants in the SCN9A Gene are Detected in a Minority of Erythromelalgia Patients by Mari Skystad Kvernebo, Celene Grayson, Ioannis M. Stylianou, Virginia Woloshen, Christopher Radomski, Cato Mørk, Knut Kvernebo

“…Gain-of-function variants in the voltage-gated sodium channel Nav1.7, encoded by the SCN9A gene, have previously been identified in patients with erythromelalgia, a clinical diagnosis defined by intermittent attacks of painful, hot, swollen, and red skin, predominantly involving the hands and feet. …”
Get full text

Risk Factors Related to the in-hospital Evolution of Patients with ST-segment Elevation Acute Coronary Syndrome by Chen Shang, Héctor Pérez Assef, Marlene Ferrer Arrocha

“…<br /><strong>Methods:</strong> a cross-sectional analytical study was carried out that included 99 patients with a diagnosis of STEACS admitted to the coronary care unit of the Institute of Cardiology and Cardiovascular Surgery, from June 2018 to June 2019. …”
Get full text

Primary Dysgerminoma of the Uterine Cervix: A Rare Case Report by Biruck Gashawbeza, Bethel Dereje, Ferid A. Abubeker

“…A high index of suspicion and an exhaustive workup are necessary to reach a diagnosis, particularly in a young patient presenting with a cervical lesion.…”
Get full text

Chronic Q Fever with Vascular Involvement: Progressive Abdominal Pain in a Patient with Aortic Aneurysm Repair in the United States by Zanthia Wiley, Sujan Reddy, Kara M. Jacobs Slifka, David C. Brandon, John Jernigan, Gilbert J. Kersh, Paige A. Armstrong

“…The most common symptoms of chronic Q fever with vascular involvement are nonspecific, including weight loss, fatigue, and abdominal pain. Criteria for diagnosis of chronic Q fever include clinical evidence of infection and laboratory criteria (antibody detection, detection of Coxiella burnetii DNA, or growth in culture). …”
Get full text

Inflammatory Myofibroblastic Tumor of the Nasal Septum by Yuri Okumura, Kazuhiro Nomura, Takeshi Oshima, Atsuko Kasajima, Takahiro Suzuki, Eichi Ishida, Toshimitsu Kobayashi

“…This case suggests that angiography is helpful in the differential diagnosis of epipharyngeal tumor in adolescence.…”
Get full text

Discharge against Medical Advice in Surgical Patients with Posttraumatic Stress Disorder: A Case Report Series Illustrating Unique Challenges by Marek Brzezinski, Maren Gregersen, Luiz Gustavo Schuch, Ricarda Sawatzki, Joy W. Chen, Grant Gauger, Jasleen Kukreja, Brian Cason

“…Discharge against medical advice (DAMA) can have detrimental effects on patient outcomes. Recently, the diagnosis of posttraumatic stress disorder (PTSD) has been linked with DAMA in the mental health setting. …”
Get full text

Plasma Granzyme B in ST Elevation Myocardial Infarction versus Non-ST Elevation Acute Coronary Syndrome: Comparisons with IL-18 and Fractalkine by Hala O. El-Mesallamy, Nadia M. Hamdy, Adel K. El-Etriby, Eman F. Wasfey

“…Thirty-six nondiabetic patients with ACS were compared to 12 control subjects. According to ACS diagnosis, the patients were classified into 22 patients with ST elevation myocardial infarction (STEMI) and 14 patients with non-ST elevation myocardial infarction or unstable angina (NSTEMI/UA). …”
Get full text

THORACIC SPINE CANAL STENOSIS WITH CAUDA EQUINE SYNDROME: CASE REPORT by Primadenny Ariesa Airlangga, Arifin Arifin

“…In cases with complaints of the cauda equina syndrome, thoracic stenosis can be the cause due to stenosis of the lower thoracic region which is the initial root of the cauda equina nerve. Confirm accurate diagnosis is with MRI.…”
Get full text

A Robust Hybrid Approach Based on Estimation of Distribution Algorithm and Support Vector Machine for Hunting Candidate Disease Genes by Li Li, Hongmei Chen, Chang Liu, Fang Wang, Fangfang Zhang, Lihua Bai, Yihan Chen, Luying Peng

“…The selected candidate disease genes may help to improve the diagnosis and treatment for diseases.…”
Get full text

Automatic Detection of Cracks in Cracked Tooth Based on Binary Classification Convolutional Neural Networks by Juncheng Guo, Yuyan Wu, Lizhi Chen, Guanghua Ge, Yadong Tang, Wenlong Wang

“…The proposed method in this article provides doctors with a more intelligent diagnostic solution, and it is not only suitable for optical photographs but also for automated diagnosis of other medical imaging images.…”
Get full text

Differences in risk factor profiles for peripheral artery disease compared to coronary, cerebral and carotid artery by Stefan Acosta, Yufeng Du, Yan Borné, Anders Gottsäter

“…Abstract The aim of this study was to evaluate the greatest drivers for development of lower extremity peripheral artery disease (PAD) in relation to coronary, precerebral, or cerebral artery disease This prospective study (Malmö Diet and Cancer study) included 26,681 participants. The diagnosis of incident PAD, coronary artery disease (CoAD), atherothrombotic ischemic stroke (IS) free from atrial fibrillation or flutter, and carotid artery disease (CaAD) was validated. …”
Get full text

Identification of Differentially Expressed Genes in COVID-19 and Integrated Bioinformatics Analysis of Signaling Pathways by Linjie Fang, Tingyu Tang, Mengqi Hu

“…All these findings will help us to understand the potential molecular mechanisms of COVID-19, which is also of great significance for its diagnosis and prevention.…”
Get full text

Dynamic Characteristics and Experimental Research of a Two-Span Rotor-Bearing System with Rub-Impact Fault by Rui Zhu, Guang-chao Wang, Qing-peng Han, An-lei Zhao, Jian-xing Ren, Xin Xia

“…The findings are helpful in further understanding the dynamic characteristics of the rub-impact fault of the two-span rotor-bearing system and provide reference for fault diagnosis.…”
Get full text

Increase in assisted suicide in Switzerland: did the socioeconomic predictors change? Results from the Swiss National Cohort by Marcel Zwahlen, Nicole Steck, Christoph Junker

“…Cancer was the most common underlying diagnosis (41.8%), but the percentage dying assisted was highest among patients with diseases of the nervous system (5.25% in the younger and 1.23% in the older age group). …”
Get full text

Pediatric and adolescent chronic myeloid leukemia: A follow-up study in Western India by Sangita A. Vanik, Dhaval Jetly, Biren Parikh, Karthik Dhandapani, Rukmini Bezbaruah

“…Conclusion: This study revealed that the CML cases in pediatric and adolescent age groups are normally present with higher WBC counts at the time of diagnosis. The association of the prognostic scoring system with treatment response was statistically insignificant. …”
Get full text

RISK FACTORS OF SOIL TRANSMITTED HELMINTHS AMONG ELEMETARY SCHOOL STUDENTS IN CENTRAL SUMBA – WEST NUSA TENGGARA by Fridolina Mau, Mefi Mariana Tallan

“…Primary data on risk factors were colleted by which qustionnaire for students fourth to sixth grade, age ranged 8-15 years old. Diagnosis was established using Kato Katz modification method. …”
Get full text

Trends in diabetes mellitus and related costs among hospital admissions in Switzerland, 2012–2020 by Hassan Abu Obaid, Pedro Marques-Vidal

“…Hence, our objectives were to assess (1) the evolution of hospitalizations for DM as first diagnosis and as comorbidity; (2) the association of DM with ICU admission, length of stay (LOS), in-hospital mortality and costs. …”
Get full text

Psychological Well-being of Cancer Patients by R.N. Mustafin, E.A. Kalyuzhny

“…An ideal strategy for patient management is joint work of psychologists and doctors, especially in communicating a diagnosis to patients, using and improving questionnaires, scales and criteria for assessing the need of cancer patients for psychological care. …”
Get full text

VEGFA, MYC, and JUN are abnormally elevated in the synovial tissue of patients with advanced osteoarthritis by Genxiang Rong, Zhenyu Zhang, Wenjing Zhan, Minnan Chen, Jingjing Ruan, Cailiang Shen

“…Our findings may provide a new direction for the clinical diagnosis and treatment of OA and insights into its pathogenesis.…”
Get full text

Two Rare Cases of Feline Toxic Epidermal Necrolysis: A Novel Therapeutic Approach With Medical-Grade Honey by Alexandra Peteoacă, Niels A. J. Cremers, Linsey J. F. Peters

“…Furthermore, these cases highlight the importance of rapid diagnosis and immediate drug withdrawal to increase the survival rate. …”
Get full text