Genetic Association Analysis of Fasting and 1- and 2-Hour Glucose Tolerance Test Data Using a Generalized Index of Dissimilarity Measure for the Korean Population by Jaeyong Yee, Yongkang Kim, Taesung Park, Mira Park

“…However, no single test may be sufficient for the diagnosis, and the World Health Organization (WHO)/International Diabetes Federation (IDF) has suggested composite criteria. …”
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M1 and M2 Functional Imprinting of Primary Microglia: Role of P2X7 Activation and miR-125b by Chiara Parisi, Giulia Napoli, Pablo Pelegrin, Cinzia Volonté

“…Amyotrophic lateral sclerosis (ALS) is a most frequently occurring and severe form of motor neuron disease, causing death within 3–5 years from diagnosis and with a worldwide incidence of about 2 per 100,000 person-years. …”
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Spinous Process Osteochondroma as a Rare Cause of Lumbar Pain by Bárbara Rosa, Pedro Campos, André Barros, Samir Karmali, Esperança Ussene, Carlos Durão, João Alves da Silva, Nuno Coutinho

“…The imagiologic exam of election for diagnosis is CT scan. When symptomatic the treatment of choice is surgical resection. …”
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Orbital Lymphoma Masquerading as Orbital Cellulitis by B. D. Chaurasiya, Ganesh Agrawal, Santosh Chaudhary, Sangeeta Shah, Anju Pradhan, Poonam Lavaju

“…A multidisciplinary approach involving ENT consultation, radiological investigation, and pathological sampling can help achieve a timely diagnosis and appropriate management.…”
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Application of Cancer Genomics to Solve Unmet Clinical Needs by Se-Hoon Lee, Sung Hoon Sim, Ji-Yeon Kim, SooJin Cha, Ahnah Song

“…In this review, we present one imaginary case of a cancer patient, with which we can think about unmet clinical needs to solve with cancer genomics in the diagnosis, prediction of prognosis, monitoring the status of cancer, and personalized treatment decision.…”
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Filter Realization of the Time-Domain Average Denoising Method for a Mechanical Signal by Wuwei Feng, Cuizhu Wang, Xin Chen, Yuzhou Shi, Meng Jiang, Di Wang

“…Time-domain averaging (TDA) is an effective signal processing technique in fault diagnosis that can extract the periodic components of interest from signals mixed with noise interference while suppressing other irrelevant periodic signals. …”
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Streptococcus constellatus Peritonitis and Subsequent Septic Shock following Intrauterine Device Removal by Joan Tymon-Rosario, Jessica M. Atrio, Hyun Ah Yoon, David Erlichman, Veronica Lerner

“…Ascending infection from the genital tract to the fallopian tubes resulting in peritonitis from Streptococcus constellatus is a rare clinical circumstance where there is minimal information in the literature to guide its diagnosis, management, and expected prognosis. Case. …”
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ACTH-Independent Cushing’s Syndrome Associated with Left Adrenocortical Oncocytoma of Uncertain Malignant Potential by Giuseppe S. Sica, Leandro Siragusa, Bruno Sensi, Vittoria Bellato, Pierangela Floris, Valentina Rovella, Alessandro Mauriello, Monia Di Prete, Rossana Telesca, Valerio Ciavoni, Carmine Cardillo, Nicola Di Daniele, Manfredi Tesauro

“…Considerations on the diagnosis, pathology findings, clinical remarks, and interventions are made.…”
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Xerostomia, Hyposalivation, and Salivary Flow in Diabetes Patients by Rosa María López-Pintor, Elisabeth Casañas, José González-Serrano, Julia Serrano, Lucía Ramírez, Lorenzo de Arriba, Gonzalo Hernández

“…We recommend new studies that use more precise and current definitions concerning the determination and diagnosis of DM patients and salivary flow collection.…”
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Massive Pulmonary Hemorrhage from Bronchial Varix by Michael Agustin, Scott Shay, Jose Gonzalez, Pei Liu, Nancy Lentz, Anna Shapiro, Nat Dumrongmongcolgul, Michael Torres, Vasin Jungtrakoolchai

“…Bronchial varix is a rare pulmonary disorder which may lead to life-threatening hemorrhage. Diagnosis is difficult because of the subtle abnormalities on radiographic and bronchoscopic examination. …”
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Management of a Female Patient with Irritable Bowel Syndrome and Somatoform Disorder by E. A. Trush, E. A. Poluektova, A. G. Beniashvili, O. S. Shifrin

“…For patients whose complaints meet the diagnostic criteria for IBS, a two-stage differential diagnosis may be justified: at the first stage, differentiation of IBS and organic diseases of the gastrointestinal tract is carried out; at the second stage - IBS and somatization disorder. …”
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Simulators of Squamous Cell Carcinoma of the Skin: Diagnostic Challenges on Small Biopsies and Clinicopathological Correlation by Kong-Bing Tan, Sze-Hwa Tan, Derrick Chen-Wee Aw, Huma Jaffar, Thiam-Chye Lim, Shu-Jin Lee, Yoke-Sun Lee

“…The careful application of time-honored diagnostic criteria, close clinicopathological correlation and a selective request for a further, deeper, or wider biopsy remain the most useful strategies to clinch the correct diagnosis. This review aims to present the key differential diagnoses of SCC, to discuss common diagnostic pitfalls, and to recommend ways to deal with diagnostically challenging cases.…”
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Patient Characteristics Associated with HCV Treatment Adherence, Treatment Completion, and Sustained Virologic Response in HIV Coinfected Patients by Glenn Wagner, Karen Chan Osilla, Jeffrey Garnett, Bonnie Ghosh-Dastidar, Laveeza Bhatti, Matthew Bidwell Goetz, Mallory Witt

“…Having a psychiatric diagnosis was associated with nonadherence, while better HCV adherence was associated with both treatment completion and SVR. …”
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Adalimumab-induced optic neuropathy in a patient with Behçet’s syndrome by Sofia Miranda, Daniel Calado, Joana Rua, Fernando Salvador

“…A 37-year-old woman with a diagnosis of Behçet’s syndrome, treated with colchicine and prednisolone, maintained low disease activity for a period of 10 years, after which, she developed a new episode of anterior uveitis. …”
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Quantifying glucose uptake at the single cell level with confocal microscopy reveals significant variability within and across individuals by Joel D. Paprocki, Patrick J. Macdonald, Yongjin Xu, Alan Cheng, Timothy C. Dunn, Sergey Y. Tetin

“…Abstract Measurement of glycated hemoglobin (HbA1c) in human red blood cells plays a critical role in the diagnosis and treatment of diabetes mellitus. However, recent studies have suggested large variation in the relationship between average glucose levels and HbA1c, creating the need to understand glucose variability at the cellular level. …”
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GILT stabilizes cofilin to promote the metastasis of prostate cancer by Dunsheng Han, Zhiming Wu, Cong Zhang, Ziwei Wei, Fan Chao, Xuefeng Xie, Jinke Liu, Yufeng Song, Xiaoming Song, Dingchang Shao, Shiyu Wang, Guoxiong Xu, Gang Chen

“…Our findings reveal a novel mechanism of GILT in PCa and provide a new potential target for the diagnosis and treatment of PCa patients.…”
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Educational intervention on COVID-19 in older adults of the Family Doctor´s Office No. 4. Cumanayagua, 2020 by Dayamí Guerra Villarpanda, Vivian González Suárez, Eneida Bravo Polanco, Rosario Cavada Fernández, Carmen Benítez Cabrera, Raquel Rubio Roque

“…<br /><strong>Methods:</strong> educational intervention carried out in a universe of 230 older adults, from which a sample of 178 dispensed elderly people belonging to the Family Doctor´s Office No. 4 in Cumanayagua was selected. A diagnosis was made to identify the level of knowledge about COVID-19, in which aspects about the disease were investigated, such as: symptoms, prevention measures, transmission routes. …”
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Molecular survey on the parasitic nematode Contracaecum spp. in fish (Planiliza abu) destined for human consumption by Alali Firas, Hussein Muayad A., Jawad Marwa

“…The Contracaecum spp. nematodes were examined by morphological and molecular techniques.The total prevalence was 32%, as 133 of 416 fish were infected in the viscera by Contracaecum spp. third stage (L3) larvae. Molecular diagnosis of the COX-2 gene in Contracaecum spp. from P. abu was used to confirm the infection and to study their population biology. …”
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Acute Rheumatic Fever: Findings of a Hospital-Based Study and an Overview of Reported Outbreaks by Upton D Allen, Michael Braudo, Stanley E Read

“…To review the characteristics of reported outbreaks of acute rheumatic fever in the United States, and to determine if there is an increase in the incidence of acute rheumatic fever in the population served by the Hospital for Sick Children, Toronto, Ontario, the authors conducted a literature search and a retrospective review of inpatients and outpatients, satisfying the revised Jones criteria for the diagnosis of acute rheumatic fever, from 1972 to 1988. …”
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A Case of Clozapine-Induced Myocarditis in a Young Patient with Bipolar Disorder by Ronny Cohen, Alla Lysenko, Thierry Mallet, Brooks Mirrer, Michael Gale, Pablo Loarte, Robert McCue

“…The patient had an admitting diagnosis of acute left ventricular systolic dysfunction likely secondary to drug-induced myocarditis (suspect clozapine) versus acute coronary syndrome. …”
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