Body Composition in Adult Patients with Thalassemia Major by Marianna Vlychou, Evangelos Alexiou, Paschalis Thriskos, Ioannis Fezoulidis, Katerina Vassiou

“…All patients had an established diagnosis of thalassemia major and followed a regular blood transfusion scheme since childhood and chelation treatment. …”
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The Relationship between a New Biomarker of Vagal Neuroimmunomodulation and Survival in Two Fatal Cancers by Y. Gidron, M. De Couck, D. Schallier, J. De Greve, J. L. Van Laethem, R. Maréchal

“…We retroactively derived markers of vagal nerve activity indexed by heart rate variability (HRV), specifically the root mean square of successive differences (RMSSD), from patients’ electrocardiograms near diagnosis. The NIM index was the ratio of RMSSD to C-reactive protein levels (RMSSD/CRP). …”
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Calcific Tendinitis of the Supraspinatus Tendon in an Infant by Masanori Wako, Jiro Ichikawa, Kensuke Koyama, Yoshihiro Takayama, Hirotaka Haro

“…Although these images were suggestive of calcific tendinitis of the supraspinatus tendon, we performed an open biopsy and resection in order to differentiate between a suspected diagnosis of calcific tendinitis, which is incredibly rare within pediatric patients, and infection or a soft tissue tumor. …”
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A Lifelong Smoker with Hypopituitarism: Rethinking the Hypothesis of a Tumor in the Hypophysis by Nestoras Mathioudakis, Alfredo Quinones-Hinojosa, Roberto Salvatori, Shehzad Basaria

“…In light of the patient’s extensive smoking history, the differential diagnosis was expanded to include metastatic lesion to the sella. …”
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Osmotic Demyelination Syndrome due to Rhabdomyolysis and Hyperosmolar Hyperglycemic Syndrome following Cardiogenic Shock by Kosuke Katano, Nozomi Fuse, Yoshitaka Asano, Kimihiro Osada, Akira Miyabe, Ryuma Ishihara, Atsushi Tosaka, Yuriko Satoh, Masako Maeda, Taisuke Mizumura, Akio Oshima, Toshitake Tamamura, Yoichi Sugimura

“…This case of ODS occurred when normonatremia led to hypernatremia, as a result of rhabdomyolysis and hyperosmolar hyperglycemic syndrome. Diagnosis was made based on the MRI brain findings.…”
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Cutaneous Adnexal Cylindroma of Breast: Epithelial Immunoreactivities for GATA-3, Mammaglobin, and E-Cadherin Do Not Equate to a Mammary Ductal Neoplasm by A. Halima, A. M. Pannunzio, E. M. Erstine, J. S. Ko, W. F. Bergfeld, R. M. Malaya, M. B. Frankel, B. C. Calhoun, C. D. Sturgis

“…The case emphasizes the importance of correlating clinical setting, imaging studies, patient history, and careful microscopic evaluation in arriving at an accurate diagnosis. This case also illustrates the point that not all “breast” tumors that are confirmed to be positive for GATA3, mammaglobin, and E-cadherin are derived from mammary ducts.…”
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Toxic epidermal necrolysis with thrombocytopenia induced by intravenous immunoglobulin: a case report and mini review by Yoshihiro Nishita, Masatoshi Taga, Nozomi Arakawa, Tomoki Ishida, Sawako Ochiai, Hiroto Ono, Fumiaki Taga, Togen Masauji

“…He developed thrombocytopenia after IVIg administration, leading to the diagnosis of thrombocytopenia due to IVIg after excluding other diseases. …”
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Severe Macular Edema in Patients with Juvenile Idiopathic Arthritis-Related Uveitis by Maria Pia Paroli, Claudia Fabiani, Giovanni Spinucci, Irene Abicca, Alfredo Sapia, Leopoldo Spadea

“…Despite ocular inflammation being controlled by topical/systemic therapy, during adolescence (mean age of appearance/diagnosis: 12.7±3.9 years) patients developed severe unilateral macular edema. …”
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Exploring Hypertrophic Cardiomyopathy Biomarkers through Integrated Bioinformatics Analysis: Uncovering Novel Diagnostic Candidates by Guanmou Li, Dongqun Lin, Xiaoping Fan, Bo Peng

“…This study aims to identify biomarkers that have a positive impact on the treatment, diagnosis, and prediction of HCM through bioinformatics analysis. …”
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PWS/AS MS-MLPA Confirms Maternal Origin of 15q11.2 Microduplication by Angelika J. Dawson, Janice Cox, Karine Hovanes, Elizabeth Spriggs

“…This imprinting allows for diagnosis of PWS or AS based on methylation status using methylation sensitive (MS) multiplex ligation dependent probe amplification (MLPA). …”
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Choroidal Thickness Analysis in Patients with Usher Syndrome Type 2 Using EDI OCT by L. Colombo, B. Sala, G. Montesano, C. Pierrottet, S. De Cillà, P. Maltese, M. Bertelli, L. Rossetti

“…Methods. 20 eyes of 10 patients with clinical signs and genetic diagnosis of Usher Syndrome type 2. Each patient underwent a complete ophthalmologic examination including Best Corrected Visual Acuity (BCVA), intraocular pressure (IOP), axial length (AL), automated visual field (VF), and EDI OCT. …”
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Insulin Resistance Predicts Atherogenic Lipoprotein Profile in Nondiabetic Subjects by Flávia De C. Cartolano, Gabriela D. Dias, Maria C. P. de Freitas, Antônio M. Figueiredo Neto, Nágila R. T. Damasceno

“…Conclusion. IR, previously DM2 diagnosis, is a strong predictor of quantitative and qualitative features of lipoproteins directly associated with an increased atherogenic risk.…”
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DNA Methyltransferase 3B Gene Promoter and Interleukin-1 Receptor Antagonist Polymorphisms in Childhood Immune Thrombocytopenia by Margarita Pesmatzoglou, Marilena Lourou, George N. Goulielmos, Eftichia Stiakaki

“…In this study, we investigated the rs2424913 single-nucleotide polymorphism (SNP) (C46359T) in DNA methyltransferase 3B (DNMT3B) gene promoter and the VNTR polymorphism of IL-1 receptor antagonist (IL-1 Ra) intron-2 in 32 children (17 boys) with the diagnosis of ITP and 64 healthy individuals. No significant differences were found in the genotype distribution of DNMT3B polymorphism between the children with ITP and the control group, whereas the frequency of allele T appeared significantly increased in children with ITP (P = 0.03, OR = 2, 95% CI: 1.06–3.94). …”
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Fludarabine/Cyclophosphamide Conditioning Regimen in Aplastic Anemia Patients Receiving Matched-Sibling Donor Transplant Is Non-inferior to ATG/Cyclophosphamide: A Single-Center Ex... by Uzma Zaidi, Mushkbar Fatima, Shafaq Abdul Samad, Kashif Shafique, Hira Fatima Waseem, Tasneem Farzana, Tahir Sultan Shamsi

“…The median time from diagnosis to transplant was 3 months (IQR, 2 to 4), and it ranged from 1 to 8 months. …”
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Loss of Appetite in Adult Patients: Effectiveness and Safety of an Appetite Stimulating Medication in an Open-Label, Investigator-Initiated Study in India by S. Nagaraj

“…Using an investigator-initiated, single-center, open-label, single-arm design, we evaluated the effectiveness and safety of the appetite-stimulating medication (15 mL) in 50 male or female patients (18–55 years old) attending the outpatient department, with a confirmed diagnosis of LOA after two weeks of therapy and assessed the change in Council on Nutrition Appetite Questionnaire (CNAQ) score and safety of the medication after two weeks of treatment. …”
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Diagnostic Study of Pathogenic Bacterial Isolated from Camel’s Pneumonic lungs Slaughtered in Al-Muthanna Province Abattoir, Iraq Using Vitek2 Compactiological approach and Vitek2... by Hayder M Watban, Nabeel M Al-Maaly

“…Additionally, microscopic examination of the bacteria using Gram staining followed by diagnosis with Vitek 2‎ system. The number of Gram-negative bacterial species isolated from camel lungs was 74 isolates, distributed as 31 (41.89%) of Klebsiella pneumoniae, 26 (35.13%) of Escherichia coli and 17 (22.97%) of Pseudomonas aeruginosa. …”
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Psychosocial Factors in End-Stage Kidney Disease Patients at a Tertiary Hospital in Australia by Charan Bale, Alexandra Douglas, Dev Jegatheesan, Linh Pham, Sonny Huynh, Atul Mulay, Dwarakanathan Ranganathan

“…Additional social work support and counselling, in addition to financial assistance from government and nongovernment agencies, may help to improve adjustment to the diagnosis and treatment plans as patients approach ESKD.…”
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Does Vitamin D Level Affect the Radiographic Severity of Osteoarthritis Knee and its Functional Status? by S. Hariprasad, Aditya Seth, S. J. Karthik, Anish N. Tawde, Ratnakar Vecham, Adarsh Annapareddy, A. V. Gurava Reddy, Rajat Jain

“…Clinical and radiological evaluations were performed to confirm the diagnosis of knee OA. Vitamin D levels were measured, and radiographic severity was assessed using the Kellgren–Lawrence grading system. …”
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Interobserver Reproducibility of Dna-Image-Cytometry in Ascus or Higher Cervical Cytology by Vu Quoc Huy Nguyen, Hans Jürgen Grote, Natalia Pomjanski, Kristiane Knops, Alfred Böcking

“…Interobserver agreement was assessed by calculating Kappa statistics. The diagnosis of DNA‐aneuploidy in the first measurements was confirmed in all cases. …”
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Subdural Effusions with Hydrocephalus after Severe Head Injury: Successful Treatment with Ventriculoperitoneal Shunt Placement: Report of 3 Adult Cases by N. Tzerakis, G. Orphanides, E. Antoniou, P. J. Sioutos, S. Lafazanos, A. Seretis

“…However, it is extremely important to make an accurate diagnosis of an SDEH and differentiate this condition from other subdural collections which require different management.…”
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