The Role of Open Lung Biopsy in Critically Ill Patients with Hypoxic Respiratory Failure: A Retrospective Cohort Study by Abdullah Almotairi, Sharmistha Biswas, Jason Shahin

“…A retrospective cohort study was performed of all consecutive patients admitted to three tertiary care, university-affiliated, ICUs during the period from January 2000 to January 2012 with the principal diagnosis of hypoxic respiratory failure and who underwent an open lung biopsy. …”
Get full text

Bilateral Jugular Vein and Sigmoid Sinus Thrombosis Related to an Inherited Coagulopathy: An Unusual Presentation by Özge Altıntaş, Azize Esra Gürsoy, Gözde Baran, Elnur Mehdi, Talip Asil

“…She reported an incidental diagnosis of right-sided IJVT when she was evaluated for hyperthyroidism ultrasonographically. …”
Get full text

Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma by Sonja Kabatnik, Xiang Zheng, Georgios Pappas, Sophia Steigerwald, Matthew P. Padula, Matthias Mann

“…Abstract Signet Ring Cell Carcinoma (SRCC) is a rare and highly malignant form of adenocarcinoma with increasing incidence and poor prognosis due to late diagnosis and limited treatment options. We employed Deep Visual Proteomics (DVP), which combines AI-directed cell segmentation and classification with laser microdissection and ultra-high sensitivity mass spectrometry, for cell-type-specific proteomic analysis of SRCC across the bladder, prostate, seminal vesicle, and a lymph node of a single patient. …”
Get full text

Whole-Body 18FDG-PET in an Arthritis Paraneoplastic Syndrome Revealed an Underlying Hematological Neoplasm by Serge Cammilleri, Marie Caroline Guzian, Jean-Pierre Mattei, Olivier Mundler, Sandrine Guis

“…We showed the first image of 18FDG-PET, which leads to a diagnosis of lymphoma in an atypical polyarthritis. …”
Get full text

Infarct volume as a predictor and therapeutic target in post-stroke cognitive impairment by Lingjia Xu, Dan Shan, Danling Wu

“…Recent studies have extensively investigated the epidemiology, diagnosis, and management of PISCI. Nevertheless, significant gaps persist in our understanding of its pathophysiological mechanisms and potential therapeutic targets, which warrants further research. …”
Get full text

Ensemble Classification Model With CFS-IGWO–Based Feature Selection for Cancer Detection Using Microarray Data by Pinakshi Panda, Sukant Kishoro Bisoy, Sandeep Kautish, Reyaz Ahmad, Asma Irshad, Nadeem Sarwar

“…ML-based model for cancer diagnosis is done using two forms of data: gene expression data and microarray data. …”
Get full text

South African Rheumatism and Arthritis Association 2024 guidelines for the management of axial spondyloarthritis by A B Maharaj, R Benitha, K Makan, R du Toit, D Haasbroek, C Balton, P Govender, M van Dam, F Paruk, B Hodkinson

“… Early diagnosis and prompt treatment initiation are essential in the management of axial spondyloarthritis (axSpA), also known as ankylosing spondylitis, remembering that underdiagnosis and overdiagnosis of axSpA are common. …”
Get full text

A Case of Urachal Carcinoma of the Abdominal Wall in a Kidney Transplant Recipient by Takuya Yamazaki, Yasushi Nagaba, Yoshitaka Shimada, Yoshinori Taoka, Satoru Minamida, Dai Koguchi, Masahiro Hagiwara, Sho Watanuki, Hide Nagaba, Kazunari Yoshida, Yasuo Takeuchi

“…An autopsy was performed, which revealed cystadenocarcinoma in the abdominal wall mass, leading to a diagnosis of urachal carcinoma.…”
Get full text

Assessment of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mean platelet volume in patients with diabetic retinopathy by Trisha Ghosh, Sanjay Kumar Daulat Thakur, Premangshu Ghosh, Trina Sengupta

“…Materials and Methods: A cross-sectional study was conducted among 60 patients with a definite diagnosis of type 2 diabetes mellitus attending the ophthalmology outpatient department of a tertiary care hospital. …”
Get full text

Previous Gestational Diabetes Mellitus and Markers of Cardiovascular Risk by Nikolaos Vrachnis, Areti Augoulea, Zoe Iliodromiti, Irene Lambrinoudaki, Stavros Sifakis, George Creatsas

“…A history of previous GDM (pGDM), associated or not with any of these metabolic abnormalities, can increase the risk of developing not only type 2 diabetes mellitus but also cardiovascular disease (CVD) independent of a diagnosis of type 2 diabetes later in life. In this paper we discuss the relationship among inflammatory markers, metabolic abnormalities, and vascular dysfunction in women with pGDM. …”
Get full text

Blastoid Variant Mantle Cell Lymphoma Expressing Aberrant CD3 and CD10 with Concurrent Small Lymphocytic Lymphoma: Establishment of a Clonal Relationship by B- and T-Cell Receptor... by Christopher L. Felten, Joel A. Chan, Dulce R. DeCastro, Jean Lopategui, Swapnil P. Rajurkar

“…Awareness of such a presentation and integration of the data from morphologic evaluation, flow cytometry, immunohistochemistry, and FISH studies is required for proper diagnosis, prognosis, and therapy.…”
Get full text

The Close Relationship between Large Bowel and Heart: When a Colonic Perforation Mimics an Acute Myocardial Infarction by Maria Francesca Secchi, Carlo Torre, Giovanni Dui, Francesco Virdis, Mauro Podda

“…Awareness of the potentially unusual clinical manifestations of retroperitoneal perforation following colonoscopy is crucial for the correct diagnosis and prompt management of colonoscopic perforation. …”
Get full text

Comparison between Conventional Decalcification and a Microwave-Assisted Method in Bone Tissue Affected with Mycetoma by Magdi Mansour Salih

“…Histopathology is a substantiated indicative method based on the assumption of a definitive diagnosis of mycetoma. It requires efficient processing of tissues including bone decalcification. …”
Get full text

Detection of Cancer Stem Cells from Patient Samples by Sofia Hakala, Anna Hämäläinen, Sanne Sandelin, Nikolaos Giannareas, Elisa Närvä

“…The existence of cancer stem cells (CSCs) in various tumors has become increasingly clear in addition to their prominent role in therapy resistance, metastasis, and recurrence. For early diagnosis, disease progression monitoring, and targeting, there is a high demand for clinical-grade methods for quantitative measurement of CSCs from patient samples. …”
Get full text

Grinspan’s Syndrome: A Rare Case with Malignant Transformation by Numan Kökten, Lokman Uzun, Ayşe Serap Karadağ, Tülay Zenginkinet, M. Tayyar Kalcıoğlu

“…Patients with OLP should be followed up periodically in a long term at close intervals for early diagnosis of malignant transformation.…”
Get full text

Exploration of Lipid Metabolism Alterations in Children with Active Tuberculosis Using UHPLC-MS/MS by Baixu Sun, Fang Liu, Qingqin Yin, Tingting Jiang, Min Fang, Li Duan, Shuting Quan, Xue Tian, Adong Shen, Kaixia Mi, Lin Sun

“…Taken together, plasma lipid metabolites are potentially useful for diagnosis of active TB in children and would provide insights into the pathogenesis of the disease.…”
Get full text

Retrospective Study Comparing Clinical Outcomes of Fixed Dental Prostheses in Matched Groups of Bruxer and Nonbruxer Patients by Mohammed Hawthan, Bruno R. Chrcanovic, Christel Larsson

“…The criteria for the diagnosis of “possible” and “probable” sleep or awake bruxism were used. …”
Get full text

A Corticobasal Syndrome Variant of Familial Creutzfeldt-Jakob Disease with Stroke-Like Onset by Ján Necpál, Martin Stelzer, Silvia Koščová, Michal Patarák

“…In our patient, mutation E200K and M129M polymorphism of the PRNP gene and typical immunohistochemical findings pointed to a diagnosis of CJD. The patient’s mother died of CJD many years ago. …”
Get full text

Pathology Databanking and Biobanking in The Netherlands, a Central Role for PALGA, the Nationwide Histopathology and Cytopathology Data Network and Archive by M. Casparie, A. T. M. G. Tiebosch, G. Burger, H. Blauwgeers, A. van de Pol, J. H. J. M. van Krieken, G. A. Meijer

“…Each excerpt contains patient identifiers, including demographic data and the so-called PALGA diagnosis. The latter is structured along five classification axes: topography, morphology, function, procedure, and diseases. …”
Get full text

Metastatic Invasive Lobular Breast Cancer Presenting Clinically with Esophageal Dysphagia by Lilit Karapetyan, Heather Laird-Fick, Reuben Cuison

“…The case highlights the importance of metastatic ILBC as a differential diagnosis for female patients with progressive dysphagia and associated ascites or pleural effusions.…”
Get full text