Intracranial Atherosclerotic Disease by Maria Khan, Imama Naqvi, Asha Bansari, Ayeesha Kamran Kamal

“…Approximately half of those affected are Asians. For diagnosis of ICAD, intra-arterial angiography is the gold standard to identify extent of stenosis. …”
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Upper Gastrointestinal Bleeding from Gastric Amyloidosis in a Patient with Smoldering Multiple Myeloma by Mihajlo Gjeorgjievski, Treta Purohit, Mitual B. Amin, Paul J. Kurtin, Mitchell S. Cappell

“…Based on this and multiple other case reports, we recommend that patients with GI bleeding and MGUS, SMM, or MM undergo EGD and pathologic examination of endoscopic biopsies of identified lesions using Congo red stains for amyloidosis for early diagnosis and treatment.…”
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Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome by Mimouni, Nour El Houda, Giacobini, Paolo

“…However, the underlying mechanisms of its transmission remain unknown, thus limiting the development of effective therapeutic strategies.This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.…”
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Pemphigus Vulgaris with Solitary Toxic Thyroid Nodule by Mostafa Alfishawy, Karim Anwar, Amira Elbendary, Ahmed Daoud

“…Thyroid function tests and thyroid scan were compatible with the diagnosis of thyrotoxicosis due to autonomous toxic nodule. …”
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TB Peritonitis Mistaken for Ovarian Carcinomatosis Based on an Elevated CA-125 by Joseph D. Boss, Christopher T. Shah, Oladoyin Oluwole, John N. Sheagren

“…This case outlines the unfortunate consequences of the misdiagnosis of what probably was an antibiotic responsive illness, resulting in an unnecessarily aggressive surgical procedure. The delay in the diagnosis of tuberculous pertitonitis resulted in an unnecessary radical resection of the patient’s reproductive organs. …”
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Appendiceal Orifice Inflammation in Ulcerative Colitis Mimicking Mucosa-Associated Lymphoid Tissue Lymphoma in the Cecum by Masaya Iwamuro, Takahide Takahashi, Takehiro Tanaka, Tomohiro Toji, Sakiko Hiraoka, Seiji Kawano, Yoshiro Kawahara, Hiroyuki Okada

“…Although MALT lymphoma in the cecum was endoscopically suspected, flow cytometry and pathological analyses led to the diagnosis of appendiceal orifice inflammation in ulcerative colitis. …”
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Knee Joint Biomechanical Gait Data Classification for Knee Pathology Assessment: A Literature Review by Mariem Abid, Neila Mezghani, Amar Mitiche

“…The review also reveals that biomechanical data during locomotion carry essential information on knee joint conditions to infer an early diagnosis. This survey paper can serve as a useful informative reference for research on the subject.…”
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A study report on the effect of COVID-19 pandemic in providing in-and-out-patient psychiatric services in a level-3 COVID hospital by Deepa Singh, Richa Pandey, Gaurav S. Yadav, Prabhat K. Agrawal, Amil H. Khan, Tapas K. Aich

“…During 3 months of tele-consultation service provided, 23.5% of patients had the diagnosis of depression, 21.4% of them had various types of headaches, 15.9% of patients had psychosis, 15.3% had anxiety disorders, and 8.8% had a bipolar-affective disorder. …”
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Oral Manifestations, Risk Factors and Management Strategies of COVID-19 Associated Mucormycosis in Tertiary Care Hospital by Pankaj Goel, Jitendra Kumar, Anshul Rai, Prateek Shakti, Gunjan Chouksey

“…The current management strategy requires early diagnosis, prompt treatment and oral rehabilitation.…”
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Angora Wool Asthma in Textile Industry by Pietro Sartorelli, Riccardo Romeo, Giuseppina Coppola, Roberta Nuti, Valentina Paolucci

“…Most of these proteins belong to the family of lipocalin, they function as carriers for small hydrophobic molecules (vitamins and pheromones). If the diagnosis of occupational asthma caused by animal hair and skin derivatives may be relatively easy by means of the challenge test, defining etiology is complicated because of the lack of in vitro tests.…”
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Clinical Significance and Pathogenic Mechanisms of Long Non-Coding RNA TRPM2-AS in Cancers by Shichen Huang MS, Bowen Li MS, Huanyu Chen MD, Cheng Rong, Zheng Yang MD, Xianqin Zhang PhD

“…The elevated levels of TRPM2-AS are associated with important clinicopathological parameters such as tumor size, tumor stage, and lymph node metastasis, revealing that TRPM2-AS could be a potential target for cancer diagnosis, prognosis and treatment. Moreover, TRPM2-AS is involved in regulating the cell proliferation, migration, invasion, apoptosis, drug or radio resistance by serving as a competing endogenous RNA, directly bounding to proteins and regulating multiple signaling pathways. …”
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Urinary Bladder Cancer in Egypt: Are There Gender Differences in Its Histopathological Presentation? by Fiorina Kyritsi, Christopher A. Loffredo, Yun-Ling Zheng, George Philips, Sania Amr

“…Compared to females, male cases were significantly older at time of diagnosis and smokers. In Egypt, regardless of the type of bladder cancer (SCC or UC), male more than female cases had evidence of SH infection, but not other histopathologic differences, in bladder tissue specimens.…”
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Arginine-Restricted Therapy Resistant Bilateral Macular Edema Associated with Gyrate Atrophy by Sibel Doguizi, Mehmet Ali Sekeroglu, Mustafa Alpaslan Anayol, Pelin Yilmazbas

“…Here, we report a 9-year-old boy with gyrate atrophy associated with bilateral macular edema at the time of diagnosis and the effect of long term metabolic control on macular edema. …”
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Periocular Myxoma in a Child by Dolores Ríos y Valles-Valles, Ana María Vera-Torres, Héctor A. Rodríguez-Martínez, Abelardo A. Rodríguez-Reyes

“…The lesion was resected with a clinical diagnosis of lacrimal sac tumor. Histopathology and immunohistochemistry proved the tumor to be a myxoma. …”
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Surgical Excision of Benign Papillomas Diagnosed with Core Biopsy: A Community Hospital Approach by Eka Rozentsvayg, Kristen Carver, Sunita Borkar, Melvy Mathew, Sean Enis, Paul Friedman

“…Cancer and high risk lesions accounted for 13 (19%) upstaging events from benign papilloma diagnosis. Our data suggests that surgical excision is warranted with core pathology of benign papilloma.…”
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Decompression of a Dentigerous Cyst Treatment in Mixed Dentition: A Case Report with 5 Years Follow-Up by Antoine Berberi, Georges Aad, Marise Nassar, Gwenaëlle Maalouf, Nabih Nader

“…Intraoral and radiological examination revealed an expansion of the buccal and lingual cortical plates associated with teeth #73, #74, and #75 and a well-limited, unilocular radiolucent image extending from the distal aspect of tooth #31 to the mesial aspect of tooth #36 involving the crowns of the unerupted teeth #33, #34, and #35. The preliminary diagnosis was in favor of a dentigerous cyst. The treatment was to extract the deciduous teeth and to use a sterile tube for decompression. …”
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Quantitative Fluorescence Determination of Long-Fragment DNA in Stool as a Marker for the Early Detection of Colorectal Cancer by Daniele Calistri, Claudia Rengucci, Chiara Molinari, Enrico Ricci, Elena Cavargini, Emanuela Scarpi, Gian Luigi Milandri, Carla Fabbri, Alberto Ravaioli, Antonio Russo, Dino Amadori, Rosella Silvestrini

“…Background: A variety of molecular markers have been evaluated for the development of a non-invasive approach to the diagnosis of colorectal cancer. We aimed to validate the diagnostic accuracy, using the same threshold as in the previous pilot study, of fluorescent long DNA test as a relatively simple and inexpensive tool for colorectal cancer detection.…”
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Fecaloma causing small bowel obstruction in the absence of risk factors: a case report by Youssef Ahmad, Umer Siddiqui, Ayman Ahmed, Aiswarya Sudheer, Tejaswi Chetla, Inayat Shergill, Fadi Souleiman

“…Conclusion This case underscores the importance of considering fecal impaction as a differential diagnosis in patients with chronic constipation and highlights the effectiveness of surgical intervention in resolving such obstructions. …”
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Prader-Willi Syndrome: Clinical Aspects by Grechi Elena, Cammarata Bruna, Mariani Benedetta, Di Candia Stefania, Chiumello Giuseppe

“…During infancy many PW child display a range of behavioural problems that become more noticeable in adolescence and adulthood and interfere mostly with quality of life. Early diagnosis of PWS is important for effective long-term management, and a precocious multidisciplinary approach is fundamental to improve quality of life, prevent complications, and prolong life expectancy.…”
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The Use of 99mTc-Methoxy-isobutyl-isonitrile (sestaMIBI) Uptake on Scintigraphy (99m-STS) in Amiodarone-Induced Thyrotoxicosis: Case Series and Review of the Literature by Ghada Elshimy, Mahmoud Alsayed, Jerome Targovnik, Gamal Sidarous, Kresimira M. Milas

“…We present a case series describing 5 patients presenting to the University of Arizona with AIT where we used 99m-STS to assess in diagnosis and treatment of different types of AIT followed by a review of the literature.…”
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