Rapid detection of carbapenem-resistant Escherichia coli and carbapenem-resistant Klebsiella pneumoniae in positive blood cultures via MALDI-TOF MS and tree-based machine learning... by Xiaobo Xu, Zhaofeng Wang, Erjie Lu, Tao Lin, Hengchao Du, Zhongfei Li, Jiahong Ma

“…The AUROC for the diagnosis of K. pneumoniae susceptibility to carbapenems by the DT, RF, GBM, XGBoost, and ERT models were 0.78, 0.95, 0.93, 0.90, and 0.95, respectively, and the accuracy in predicting 127 K. pneumoniae-positive blood cultures were 0.76, 0.86, 0.81, 0.80, and 0.76, respectively. …”
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Pyogenic Granuloma of the Larynx: A Case Report by Moallim Hussein AA, Sheikh OA, Mukhtar AA, Abdi IA, Ahmed NM, Mohamed SS, Kahiye MA, Nur MA, Asseyr AF

“…Some of the conditions considered in the differential diagnosis include hemangioma, hemangioendothelioma, angiofibroma, angiosarcoma, Kaposi sarcoma, Wegener’s granuloma, Crohn’s disease, granulomatous infections such as tuberculosis and histoplasmosis, traumatic granuloma, carcinosarcoma, as well as verrucous and squamous cell carcinoma.Conclusion: We present a case report of lobular capillary hemangioma of the larynx, including its histopathological diagnosis and management course.Keywords: vocal cord, laryngoscope, hemangioma, bartonella…”
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Conversion from clinically isolated syndrome to multiple sclerosis: what paraclinical tests findings are the most characteristic? by M. Malciūtė, I. Čelpačenko, R. Stankevičiūtė, R. Balnytė

“…The data were obtained from medical records and included findings of paraclinical tests (magnetic resonance imaging (MRI), IgG levels and oligoclonal bands (OCBs) in cerebrospinal fluid (CSF), and brainstem auditory evoked potential (BAEP)) and final diagnosis. The patients were divided into 2 groups according to the final diagnosis (MS group and non-MS group) and into 3 age groups (18-30, 30-50, >50 years old). …”
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Tuberculous pericarditis due to silicon oxide exposure. A case report with an imaging approach by Andrés Felipe Donado-Moré, Jorge Ignacio Arrieta-Castaño, Lina Fernanda Acevedo-Forero, Jorge Alberto Carrillo-Bayona, Alejandro Vega-Molina, Wilmer Orlando Aponte-Barrios, Oscar Andrés Franco-Tavera

“…The only positive test was adenosine deaminase (ADA), thus raising the suspicion of tuberculous pericarditis. The definitive diagnosis was obtained via pericardial biopsy. Daily oral antituberculosis treatment was administered for 56 days, resulting in a significant improvement in the patient's condition. …”
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Artificial Intelligence and Radiomics in Cholangiocarcinoma: A Comprehensive Review by Marta Zerunian, Tiziano Polidori, Federica Palmeri, Stefano Nardacci, Antonella Del Gaudio, Benedetta Masci, Giuseppe Tremamunno, Michela Polici, Domenico De Santis, Francesco Pucciarelli, Andrea Laghi, Damiano Caruso

“…CCA still has an extremely high unfavorable prognosis, regardless of type and location, and complete surgical resection remains the only curative therapeutic option; however, due to the underhanded onset and rapid progression of CCA, most patients present with advanced stages at first diagnosis, with only 30 to 60% of CCA patients eligible for surgery. …”
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Role of Cathepsin S in Periodontal Inflammation and Infection by S. Memmert, A. Damanaki, A. V. B. Nogueira, S. Eick, M. Nokhbehsaim, A. K. Papadopoulou, A. Till, B. Rath, S. Jepsen, W. Götz, C. Piperi, E. K. Basdra, J. A. Cirelli, A. Jäger, J. Deschner

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Alu insertion polymorphisms and susceptibility to metabolic syndrome in a Moroccan population by Hamid Farhane, Majida Motrane, Karchali Soufaine, Fatima-Ezzahra Anaibar, Aïcha Motrane, Said Nassor Abeid, Abderraouf Hilali, Nourdin Harich

“…The diversity of the combination of its main components, conditioned by genetics and environmental risk factors, contributes to the complexity of this health condition and increases the difficulty of its diagnosis and treatment. Objective Our study aimed to explore the association between four Alu insertion polymorphisms and the risk of MetS as well as its components in the Doukkala population of Morocco. …”
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The Role of Advanced Cardiac Imaging in Monitoring Cardiovascular Complications in Patients with Extracardiac Tumors: A Descriptive Review by Annamaria Tavernese, Valeria Cammalleri, Rocco Mollace, Giorgio Antonelli, Mariagrazia Piscione, Nino Cocco, Myriam Carpenito, Carmelo Dominici, Massimo Federici, Gian Paolo Ussia

“…Cardiac involvement in cancer is increasingly important in the diagnosis and follow-up of patients. A thorough cardiovascular evaluation using multimodal imaging is crucial to assess any direct cardiac involvement from oncological disease progression and to determine the cardiovascular risk of patients undergoing oncological therapies. …”
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A beneficial levels of 25-hydroxyvitamin D for a decrease in thyrotropin receptor antibody (TRAB) in patients with Graves’ disease: a real-world study by Xide Chen, Yongze Zhang, Luxi Lin, Yuxia Chen, Ximei Shen, Lingning Huang, Fengying Zhao, Sunjie Yan

“…The level of 25-hydroxyvitamin D at the time of initial diagnosis was not associated with the re-normal of free Triiodothyronine(FT3), free thyroxineIndex(FT4) or TSH levels during the follow-up. …”
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Reduced Presence of SARS-CoV-2 microRNA-like Small RNA in the Serum of Patients with Post-Acute Sequelae SARS-CoV-2 Infection by Maria Alfreda Stincarelli, Isabella Abbate, Giulia Matusali, Michele Tanturli, Marta Camici, Rosaria Arvia, Elisabetta Lazzari, Eleonora Cimini, Alessandra Vergori, Fabrizio Maggi, Simone Giannecchini

“…Then, the expression of three SARS-CoV-2 small RNAs was studied in both nasopharyngeal swabs (NPS) and sera from 24 patients at their initial COVID-19 diagnosis (T0) and in sera collected 91 to 193 days post-diagnosis (T1). …”
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Deciphering the Role of CD36 in Gestational Diabetes Mellitus: Linking Fatty Acid Metabolism and Inflammation in Disease Pathogenesis by Huang L, Zhang T, Zhu Y, Lai X, Tao H, Xing Y, Li Z

“…Li Huang,1– 3,* Tong Zhang,4,* Yuanyuan Zhu,5 Xueling Lai,6 Hualin Tao,1– 3 Yuhan Xing,5 Zhaoyinqian Li1– 3 1Department of Laboratory Medicine, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 2Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases, Luzhou, Sichuan, People’s Republic of China; 3Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Luzhou, Sichuan, People’s Republic of China; 4Department of Laboratory Medicine, Southwest Medical University, Luzhou, Sichuan, People’s Republic of China; 5School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, Guangdong, People’s Republic of China; 6Shenzhen Guangming Maternal & Child Healthcare Hospital, Shenzhen, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhaoyinqian Li, Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Jiangyang District, Luzhou, Sichuan, 646000, People’s Republic of China, Email lizhaoyinqian@swmu.edu.cn Yuhan Xing, School of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, People’s Republic of China, Email xingyh8@mail.sysu.edu.cnAbstract: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications which exerts detrimental effects on mothers and children. …”
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Association between sleep disorders and subsequent heart failure by Jamschid Sedighi, Mark Luedde, Julia Gaensbacher-Kunzendorf, Hans-Joerg Hippe, Pascal Bauer, Birgit Assmus, Samuel Sossalla, Karel Kostev

“…Conclusion: In this large cohort of outpatients, a prior diagnosis of sleep disorders was linked to a higher incidence of HF. …”
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Preparation and application evaluation of monoclonal antibodies against Monkeypox virus A29 protein by Ai Xiangjun, Zhang Xinlan, Xu Ye, Tan Chufan, Tan Chufan, Duan Chen, Liao Nami, Liu Junxi, Qiu Yilan, Qiu Yilan, Hou Defu, Hou Defu, Wang Qinglin, Wang Qinglin, Liu Rushi, Liu Rushi

“…The experimental results indicate that monoclonal antibodies against the A29 protein hold significant potential for application in the diagnosis of MPXV.…”
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Comparison of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy Device for Lymphadenopathy by Yuki Tanisaka, Masafumi Mizuide, Akashi Fujita, Tomoya Ogawa, Ryuichiro Araki, Masahiro Suzuki, Hiromune Katsuda, Youichi Saito, Kazuya Miyaguchi, Tomoaki Tashima, Yumi Mashimo, Masami Yasuda, Shomei Ryozawa

“…Background. Accurate diagnosis of benign and malignant lymphadenopathy is important for determining the appropriate treatment and prognosis. …”
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Quantification of Myocardial Biomarkers in Sudden Cardiac Deaths Using a Rapid Immunofluorescence Method for Simultaneous Biomarker Analysis by Matteo Antonio Sacco, Valerio Riccardo Aquila, Saverio Gualtieri, Roberto Raffaele, Maria Cristina Verrina, Lucia Tarda, Santo Gratteri, Isabella Aquila

“…Background/Objectives: Differential diagnosis of sudden cardiac death (SCD) remains challenging, particularly in cases lacking evident structural abnormalities. …”
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Proximal bronchiolar adenoma with malignant transformation to invasive mucinous adenocarcinoma with 4 years follow-up: a case report and literature review by Yuan-Hui Yang, Ke Yin, Jia-Qi Xu, Xiao-Ying Xu, Jun-Lei Zhang, Ji-Xuan Liu, Xin-Zhi Feng, Xiao-Yan Lin, Xiao-Yan Lin

“…The postoperative pathological diagnosis revealed BA with mucous gland structure formation combined with partial basal cell loss, raising the possibility of malignant transformation into IMA. …”
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Determinants of Diabetic Nephropathy among Diabetic Patients in General Public Hospitals of Tigray, Ethiopia, 2018/19 by Teklewoini Mariye Zemicheal, Degena Bahrey Tadesse, Hagos Tasew Atalay, Girmay Teklay Weldesamuel, Gebrewahd Bezabh Gebremichael, Haben Nuguse Tesfay, Teklehaimanot Gereziher Haile

“…More attention has to be also given for old aged diabetic patients, long duration since diagnosis of diabetes mellitus, hypertension, and other comorbidities.…”
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Access to healthcare: waiting time until the surgical procedure by Cassiane de Santana Lemos, Ana Maria Muller Magalhães, Danielle Saraiva Tuma dos Reis, Alessandra Yuri Takehana de Andrade, Karla Cristina de Almeida, Fabiana Zerbieri Martins, Nancy Reynolds, Vanessa de Brito Poveda

“…Background Understanding the determinants that limit the population’s access to surgical care in health services is highly relevant in order to provide data to support political interventions.Objective This study aimed to evaluate the time between diagnosis and elective surgery in adult patients with the longest waiting lists in Brazil; identify the determinants that interfere with access to the health service to perform surgery; and analyze the quality of life after the indicative diagnosis of surgical intervention.Methods A cross-sectional study was conducted with adult patients treated at three hospitals in the Southeast, North and South regions of Brazil, from October 2020 to October 2022. …”
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Joint Analysis of Multiple Omics to Describe the Biological Characteristics of Resistant Hypertension by Shanshan Wang, Yuanlong Hu, Yuqi Wang, Yueyue Song, Dan Liang, Jiufeng Yin, Yunlun Li, Wenqing Yang, Dan Zhang

“…Mining biological characteristics is crucial for exploring the pathogenesis of RH and for early diagnosis and treatment. Although several single‐omics studies have been conducted on RH, its complex pathogenesis has only been partially elucidated. …”
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Tear metabolomics reveals novel potential biomarkers in epithelial herpes simplex keratitis by Jinyu Zhang, Zhenning Wu, Yangqi Zhang, Kaili Wu, Xiaoyi Li, Shiyou Zhou

“…These findings may provide novel insights into early and rapid diagnosis of HSK.…”
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