Changes in Physical Activity Across Cancer Diagnosis and Treatment Based on Smartphone Step Count Data Linked to a Japanese Claims Database: Retrospective Cohort Study by Yoshihide Inayama, Ken Yamaguchi, Kayoko Mizuno, Sachiko Tanaka-Mizuno, Ayami Koike, Nozomi Higashiyama, Mana Taki, Koji Yamanoi, Ryusuke Murakami, Junzo Hamanishi, Satomi Yoshida, Masaki Mandai, Koji Kawakami

“…The observation period spanned from 6 months before diagnosis to 12 months after diagnosis. We applied a generalized additive mixed model with a cubic spline to describe changes in step counts before and after diagnosis. …”
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Epidemiology and Performances of Typhidot Immunoassay and Widal Slide Agglutination in the Diagnosis of Typhoid Fever in Febrile Patients in Bafoussam City, Cameroon: A Cross-Sectional Comparative Study by Aurelie Dahlia Yemeli Piankeu, Siméon Pierre Chegaing Fodouop, Michel Noubom, Emmanuel Boris Gomseu Djoumsie, Georges Ful Kuh, Donatien Gatsing

“…Enteric fever is a great public health problem associated with significant illness and death in many endemic countries, and its clinical diagnosis is still daunting. The aim of this study was to determine the prevalence and risk factors of S. …”
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Diagnostic yield and safety of transbronchial lung cryobiopsy for diffuse parenchymal lung diseases diagnosis: Comparison between 1.7-mm and 1.9-mm probes by C. Ravaglia, F. Sultani, S. Piciucchi, A. Dubini, A. J. De Grauw, S. Martinello, S. Oldani, S. Maitan, F. Stella, V. Poletti

“…The purpose of this randomized controlled study was to evaluate, for the first time, the quality and safety of biopsy specimens obtained by using the new disposable 1.7-mm cryoprobe compared with the standard re-usable 1.9 mm cryoprobe in the diagnosis of diffuse parenchymal lung diseases. Methods: 60 consecutive patients were prospectively enrolled and randomly assigned to two different groups: 1.9 mm (group A) and 1.7 mm (group B); primary endpoints were pathological and multidisciplinary diagnostic yield, sample size and complication rate. …”
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New Insight into Laboratory Tests and Imaging Modalities for Fast and Accurate Diagnosis of COVID-19: Alternative Suggestions for Routine RT-PCR and CT—A Literature Review by Amir Khorasani, Amir Chegini, Arezoo Mirzaei

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MPO Expression of Background Neutrophils in MPO Negative Acute Promyelocytic Leukemia, An Easy Clue to Corroborate a Challenging Diagnosis: A Case Report and Review of Literature by Kritika Krishnamurthy, Jui Choudhuri, K. H. Ramesh, Yanhua Wang

“…Early recognition of APL with prompt ATRA induction has a decisive impact on the early death rate. The preliminary diagnosis of APL relies heavily on cytomorphology and flow cytometry. …”
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Diagnostic Performance between Histidine-Rich Protein 2 (HRP-2), a Rapid Malaria Diagnostic Test and Microscopic-Based Staining Techniques for Diagnosis of Malaria by Jean Baptiste Niyibizi, Emmanuel Kamana Gatera

“…Further studies should determine the most appropriate type of rapid diagnostic test of malaria diagnosis to be used in combination with Giemsa microscopy. …”
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Advanced One-Pot RPA-CRISPR/Cas12a Reaction with Glycerol and Betaine for High-Sensitivity Diagnosis of mecA-Carrying Strains in Clinical Samples by Jingyuan Wang, Dan Wang, Linlin Fan, Xin Ye, Jian Hu, Xiaoqin Wang

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Grey Zones in the Diagnosis of Adult Migraine without Aura Based on the International Classification of Headache Disorders-Iii Beta: Exploring the Covariates of Possible Migraine without Aura by Aynur Ozge, Elif Aydinlar, Bahar Tasdelen

“…BACKGROUND: Exploring clinical characteristics and migraine covariates may be useful in the diagnosis of migraine without aura.…”
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No Contribution of GAD-65 and IA-2 Autoantibodies around Time of Diagnosis to the Increasing Incidence of Juvenile Type 1 Diabetes: A 9-Year Nationwide Danish Study by Steffen U. Thorsen, Christian B. Pipper, Henrik B. Mortensen, Flemming Pociot, Jesper Johannesen, Jannet Svensson

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Generating evidence on screening, diagnosis and management of non-communicable diseases during pregnancy; a scoping review of current gap and practice in India with a comparison of Asian context. by Theophilus Lakiang, Sonali Abner Daniel, Kauma Kurian C, Minashree Horo, Shumayla Shumayla, Sunil Mehra

“…<h4>Results</h4>Screening, diagnosis, and management of these three conditions vary and no single universally accepted criteria for diagnosis and management exist to date. …”
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Urinary exosomal miRNA-451a can be used as a potential noninvasive biomarker for diagnosis, reflecting tubulointerstitial damage and therapeutic response in IgA nephropathy by Qiong Zhang, Yan Zhao, Yankun Luo, Songjia Guo, Haizhu Hou, Xiaoli Han, Yun Zhou

“…The levels of baseline miR-451a in the complete remission group were significantly higher than those in the non-complete remission group. uE miR-451a expression was significantly elevated in patients with IgA nephropathy and may serve as a potential biomarker for the diagnosis of IgAN and evaluation of tubulointerstitial damage, while the baseline levels of uE miR-451a may be predictors of therapeutic efficacy and disease progression.…”
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Editorial: Multisystem inflammatory syndrome observed post-COVID-19: the role of natural products, medicinal plants and nutrients and the use of prediction tools supporting traditional forms of diagnosis by Anthony Booker, Anthony Booker, Ioannis Zabetakis, Nicole Elisabeth Teusch, Andrew Dalby, Thomas Hartung, Thomas Hartung, Angela E. Peter

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The Kleine-Levin Syndrome: A Rare Disease with Often Delayed Diagnosis—A Report of Two Cases in the Department of Neurology of the University Hospital of Cocody (Côte d’Ivoire) by Berthe Assi, Constance Yapo-Ehounoud, Mohamed Ben Allaoui Baby, Evelyne Aka-Diarra, Muriel Amon-Tanoh, Christian Tanoh

“…This diagnosis was delayed due to failure to understand the pathology, thereby leading patients to wandering. …”
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Cost Impact Model of a Novel Multi-mRNA Host Response Assay for Diagnosis and Risk Assessment of Acute Respiratory Tract Infections and Sepsis in the Emergency Department by John E. Schneider, Jonathan Romanowsky, Philipp Schuetz, Ivana Stojanovic, Henry K. Cheng, Oliver Liesenfeld, Ljubomir Buturovic, Timothy E. Sweeney

“…Included costs were those assumed to be associated with an episode of sepsis diagnosis, management, and treatment. Projected accuracies for test predictions, disease prevalence, and clinical parameters was derived from patient-level meta-analysis data of randomized trials, supplemented with published performance data for HostDx Sepsis. …”
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What are the barriers to the diagnosis and management of chronic respiratory disease in sub-Saharan Africa?... by Angela Obasi, Rachel Tolhurst, Kingsley Rex Chikaphupha, Miriam Taegtmeyer, Kevin Mortimer, Louis Niessen, Maia Lesosky, Jahangir Khan, William Worodria, Jamie Rylance, Lindsay Zurba, Imelda Bates, Stellah G Mpagama, Elizabeth Henry Shayo, Rose Oronje, Emmanuel Addo-Yobo, Brian Allwood, Hastings Banda, Amsalu Binegdie, Adegoke Falade, Bertrand Mbatchou, Beatrice Mutayoba, Nyanda Elias Ntinginya, Heather Zar, Eliya Zulu, Helen Meme, Uzochukwu Egere, Asma Elsony, Martha Chinouya, S Bertel Squire, Stephen Mulupi, Irene Ayakaka, Nicole Kozak, Elhafiz Abdalla, Rashid Osman

“…CRD are underdiagnosed, under-reported and underfunded, leading to a vicious cycle of invisibility and neglect. Appropriate diagnosis and management require health systems strengthening, particularly at the primary healthcare level.…”
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Gadospin F—Enhanced Magnetic Resonance Imaging for Diagnosis and Monitoring of Atherosclerosis: Validation with Transmission Electron Microscopy and X-Ray Fluorescence Imaging in the Apolipoprotein E—Deficient Mouse by Caroline Jung, Tanja Dučić, Rudolph Reimer, Eva Koziolek, Fabian Kording, Markus Heine, Gerhard Adam, Harald Ittrich, Michael G. Kaul

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Elevated BP180 ELISA at Diagnosis Correlates with Disease Severity and Relapse in Oral Mucous Membrane Pemphigoid: Preliminary Results from a Retrospective Monocentric Italian Study by Andrea Gabusi, Davide B. Gissi, Roberto Rossi, Federica Filippi, Camilla Loi, Cosimo Misciali, Giacomo Clarizio, Michelangelo La Placa, Federico Bardazzi

“…Clinical severity at diagnosis was measured using the oral disease severity score (ODSS). …”
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Clinical Practice Guidelines of the Russian Society for the Study of the Liver, the Russian Gastroenterological Association, the National Scientific Society of Infectious Disease Specialists for the Diagnosis and Treatment of Chronic Hepatitis C by V. T. Ivashkin, V. P. Chulanov, N. A. Mamonova, M. V. Maevskaya, M. S. Zharkova, I. N. Tikhonov, P. O. Bogomolov, E. V. Volchkova, A. S. Dmitriev, O. O. Znojko, E. A. Klimova, K. V. Kozlov, I. E. Kravchenko, E. Yu. Malinnikova, R. V. Maslennikov, M. I. Mikhailov, K. E. Novak, I. G. Nikitin, V. E. Syutkin, E. V. Esaulenko, A. A. Sheptulin, E. N. Shirokova, N. D. Yushchuk

“…Аim: diagnosis and treatment algorithms in the clinical recommendations intended for general practitioners, gastroenterologists, infectious disease specialists, hepatologists on the of chronic hepatitis C are presented.Summary. …”
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Diagnosis of the vegetation cover in the wetlands of La Caimanera Swamp, Colombia and Casitas Wetland, Mexico by means of Landsat and Sentinel-2A images during last four decades by Gastón Ballut-Dajud, Erick Arturo Betanzo-Torres, Luis Carlos Sandoval Herazo

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Accuracy of algorithms to identify patients with a diagnosis of major cancers and cancer-related adverse events in an administrative database: a validation study in an acute care hospital in Japan by Takashi Fujiwara, Yasuyuki Okumura, Hironobu Tokumasu, Takashi Kanemitsu, Kosei Tajima, Akinori Yuri, Masahiro Iwasaku

“…This study was conducted to evaluate the accuracy of diagnosis and adverse event (AE) definitions for specific cancers in a Japanese health administrative real-world database (RWD).Design and setting Retrospective observational validation study to assess the diagnostic accuracy of electronic medical records (EMRs) and claim coding regarding oncology diagnosis and AEs based on medical record review in the RWD. …”
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