Prognostic Factor Analysis of Intraocular Pressure with Neovascular Glaucoma by Satoko Nakano, Takako Nakamuro, Katsuhiko Yokoyama, Kunihiro Kiyosaki, Toshiaki Kubota

“…We retrospectively reviewed 142 NVG patients (181 eyes) with ischemic retinal diseases [proliferative diabetic retinopathy (PDR) in 134 eyes, retinal vein occlusion (RVO) in 29, and ocular ischemic syndrome in 18]. …”
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High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations by Olena Puzyeyeva, Wai Ching Lam, John G. Flanagan, Michael H. Brent, Robert G. Devenyi, Mark S. Mandelcorn, Tien Wong, Christopher Hudson

“…The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). …”
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Distribution of Pupil Size and Associated Factors: Results from the Population-Based Gutenberg Health Study by Marian Kiel, Stephanie D. Grabitz, Susanne Hopf, Thomas Koeck, Philipp S. Wild, Irene Schmidtmann, Karl J. Lackner, Thomas Münzel, Manfred E. Beutel, Norbert Pfeiffer, Alexander K. Schuster

“…This should be taken into account when planning nonmydriatic fundus photography-based screening programs, for instance, for diabetic retinopathy.…”
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Qatari Genotype May Contribute to Complications in Type 2 Diabetes by Youssra Dakroury, Stephen L. Atkin, Soha R. Dargham, Amal Robay, Juan Rodriguez-Flores, Ronald G. Crystal, Alexandra E. Butler

“…Therefore, three genotype-based Qatari ancestral groups, Q1 Arab Bedouin, Q2 Asian/Persian, and Q3 sub-Saharan African, with a fourth admixed group were correlated with T2DM prevalence and its complications to determine if they differed between the 4 Qatari ancestries, particularly for the SLMAP allele-associated diabetic retinopathy. Methods. In this cross-sectional study, 398 Qatari subjects, 220 with and 178 without T2DM, were genotyped by Affymetrix 500k SNP arrays. …”
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Efficacy Comparison of Intravitreal Anti-VEGF Therapy for Three Subtypes of Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis by Jianqing Li, Jiayi Xu, Yiyi Chen, Jiaju Zhang, Yihong Cao, Peirong Lu

“…At 12 months, the mean changes in Early Treatment of Diabetic Retinopathy Study (ETDRS) letters were 6.38, 8.12, and 9.37, while the MT decrease was 126.51, 126.52, and 139.85 μm, respectively. …”
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Automated Detection of Macular Diseases by Optical Coherence Tomography and Artificial Intelligence Machine Learning of Optical Coherence Tomography Images by Soichiro Kuwayama, Yuji Ayatsuka, Daisuke Yanagisono, Takaki Uta, Hideaki Usui, Aki Kato, Noriaki Takase, Yuichiro Ogura, Tsutomu Yasukawa

“…The diagnoses involved normal eyes (n=570) and those with wet age-related macular degeneration (AMD) (n=136), diabetic retinopathy (DR) (n=104), epiretinal membranes (ERMs) (n=90), and another 19 diseases. …”
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Prevalence of Chronic Complications, Their Risk Factors, and the Cardiovascular Risk Factors among Patients with Type 2 Diabetes Attending the Diabetic Clinic at a Tertiary Care Ho... by Maulee Hiromi Arambewela, Noel P. Somasundaram, Hettiarachchige Buddhi Pradeep Ranjan Jayasekara, Mahesh P. Kumbukage, Pulukkutti Mudiyanselage Sarath Jayasena, Chandrasekara Mudalige Priyanka Hemanthi Chandrasekara, Kurukulasuriya Ravindra Alexis Sudath Fernando, Divadalage Priyantha Kusumsiri

“…Prevalence of CAD, stroke, and peripheral vascular disease were 10.6%, 1.1%, and 4.7% while diabetic retinopathy, neuropathy, nephropathy, diabetic foot, and lower extremity amputation (LEA) were 26.1%, 62.6%, 50.8%, 2.6%, and 1.3%, respectively. …”
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The protective role of GLP-1 in neuro-ophthalmology by Sohum Sheth, Aashay Patel, Marco Foreman, Mohammed Mumtaz, Akshay Reddy, Ramy Sharaf, Siddharth Sheth, Brandon Lucke-Wold

“…Furthermore, the preclinical works which unravel the effects of GLP-1 in ocular dynamics and the preclinical literature regarding GLP-1RA use in the management of several neuro-ophthalmic conditions, including diabetic retinopathy (DR), glaucoma, and idiopathic intracranial hypertension (IIH) are discussed.…”
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Ocular Aberrations and Retinal Thickness Variations After Moderate-Term Reading on Electronic Devices by Age by María Arcas-Carbonell, Elvira Orduna-Hospital, María Mechó-García, María Munarriz-Escribano, Ana Sanchez-Cano

“…Parameters such as total aberration, high-order aberration (HOA), low-order aberration (LOA), and retinal thickness in the nine Early Treatment Diabetic Retinopathy Study (ETDRS) areas were measured. The sample was analyzed as a whole and divided into five age groups by decade. …”
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Analysis of the morbidity characteristics and related factors of pulmonary nodules in patients with type 2 diabetes mellitus: a retrospective study by Jie Yang, Wenna Wang, Yizhen Lu, Chunyao Li, Shuwu Wei, Weiwei Sun

“…Results Compared to the non-PNs group, the PNs Patients in the group had a longer duration of diabetes, higher age, serum creatinine (SCR), blood urea nitrogen (BUN) and the lower albumin (ALB) and body mass index (BMI); women, diabetic retinopathy (DR), diabetic peripheral neuropathy (DPN), and estimated glomerular filtration rate (eGFR) < 60 ml/min1.73m2 were more represented in the PNs group; there were fewer patients with overweight in the PNs group. …”
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Neovascular Glaucoma from Ocular Ischemic Syndrome Treated with Serial Monthly Intravitreal Bevacizumab and Panretinal Photocoagulation: A Case Report by Hassaan Asif, Zhuangjun Si, Steven Quan, Pathik Amin, David Dao, Lincoln Shaw, Dimitra Skondra, Mary Qiu

“…Fundoscopy revealed midperipheral dot-blot hemorrhages without diabetic retinopathy or vein occlusion. Fluorescein angiography revealed peripheral retinal nonperfusion in both eyes. …”
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Chinese Herbal Medicine Combined with Intravitreal Antivascular Growth Factor Agents in Treatment of Macular Edema Secondary to Retinal Vein Occlusion: A Systematic Review and Meta... by Su Xiaojuan, Li Xiaodong, Fu Zhongmei, Ye Hejiang

“…Retinal vein occlusion (RVO) is the second most common retinal vascular disease in the world after diabetic retinopathy. Moreover, macular edema (ME) is the main cause of visual impairment in RVO patients. …”
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Characterizing Flow and Structure of Diabetic Retinal Neovascularization after Intravitreal Anti-VEGF Using Optical Coherence Tomography Angiography: A Pilot Study by Christof Haensli, Katrin Fasler, Daniel Barthelmes, Sandrine A. Zweifel

“…Patients with proliferative diabetic retinopathy (PDR) were treated with intravitreal antiVEGF injections. …”
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Circ-ADAM9 Promotes High Glucose-Induced Retinal Pigment Epithelial Cell Injury in DR via Regulating miR-338-3p/CARM1 Axis by Zeyu Liang, Chengzhe Lu, Tingting Feng, Xiang Gao, Yongfang Tu, Wenchao Yang, Yipeng Wang

“…Circular RNAs (circRNAs) have been reported to be involved in the regulation of retinal pigment epithelial (RPE) cell injury and are closely related to the development of diabetic retinopathy (DR). More research is needed to confirm the role and mechanism of circ-ADAM9 in DR progression. …”
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miR-126 Mimic Counteracts the Increased Secretion of VEGF-A Induced by High Glucose in ARPE-19 Cells by Roberta Sanguineti, Alessandra Puddu, Massimo Nicolò, Carlo Enrico Traverso, Renzo Cordera, Giorgio L. Viviani, Davide Maggi

“…Vascular endothelial growth factor-A (VEGF-A) has a pathologic role in microvascular diabetic complication, such as diabetic retinopathy (DR). miR-126 plays an important role in vascular development and angiogenesis by regulating the expression of VEGF-A. …”
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Correlation between Transient Pupillary Light Reflex and Retinal Function Impairment in Patients with Retinitis Pigmentosa by Yan He, Huanyu Tang, Gang Wang, Bangqi Ren, Yi Wang, Yong Liu

“…Best-corrected visual acuity (BCVA) was recorded based on Early Treatment Diabetic Retinopathy Study (ETDRS) acuity charts. Fixation stability and retinal sensitivity of radial 10° areas were measured with microperimetry. …”
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Clinical Predictors of Nondiabetic Kidney Disease in Patients with Diabetes: A Single-Center Study by Francesco Fontana, Rossella Perrone, Francesco Giaroni, Gaetano Alfano, Silvia Giovanella, Giulia Ligabue, Riccardo Magistroni, Gianni Cappelli

“…Patients in the NDKD group had significantly lower HbA1C, lower prevalence of diabetic retinopathy (DR), and less severe proteinuria, and there was a lower proportion of patients with nephrotic syndrome; the DKD group had significantly lower proportion of patients with hematological conditions. …”
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High-Mobility Group Box-1 Induces Decreased Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in the Diabetic Retina by Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Mohammad Mairaj Siddiquei, Abdullah S. Al-Kharashi, Dustan Kangave, Ghulam Mohammad

“…To test the hypothesis that brain-derived neurotrophic factor-(BDNF-) mediated neuroprotection is reduced by high-mobility group box-1 (HMGB1) in diabetic retina, paired vitreous and serum samples from 46 proliferative diabetic retinopathy and 34 nondiabetic patients were assayed for BDNF, HMGB1, soluble receptor for advanced glycation end products (sRAGE), soluble intercellular adhesion molecule-1 (sICAM-1), monocyte chemoattractant protein-1 (MCP-1), and TBARS. …”
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Serum Cystatin C, Markers of Chronic Kidney Disease, and Retinopathy in Persons with Diabetes by Chee Wai Wong, Boon Wee Teo, Ecosse Lamoureux, Mohammad Kamran Ikram, Jie Jin Wang, E. Shyong Tai, Sunil Sethi, Tien Yin Wong, Charumathi Sabanayagam

“…We examined the association of CKD defined by serum creatinine, serum cystatin C, and albuminuria with moderate diabetic retinopathy (DR). Methods. We examined 1,119 Indian adults with diabetes, aged 40–80 years, who participated in the Singapore Indian Eye Study (2007–2009), a population-based cross-sectional study. …”
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A Novel Risk Score Model for the Differential Diagnosis of Type 2 Diabetic Nephropathy: A Multicenter Study by Yuetong Zhao, Lin Liu, Li Zuo, Xianghai Zhou, Song Wang, Hongwei Gao, Feng Yu, Xiaomei Zhang, Mi Wang, Ling Chen, Rui Zhang, Fang Zhang, Shuhong Bi, Qiong Bai, Jiaxiang Ding, Qinghua Yang, Sixu Xin, Sanbao Chai, Min Chen, Junqing Zhang

“…Finally, we conducted internal and external validation of the model with ROC curves. Results. Diabetic retinopathy, diabetes duration≥5 years, eGFR<30 ml/min/1.73 m2, 24 h UTP≥3 g, and no hematuria were independent risk factors (P<0.05), and each factor scored 2, 1, 1, 1, and 1. …”
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