-
221
The Prevalence and Causes of Visual Impairment in Type 2 Diabetes Mellitus in Northeast China
Published 2020-01-01“…Uncorrected refractive error and cataract remain the leading cause of visual impairment, but the major challenge is the early diagnosis and intervention of diabetic retinopathy to reduce diabetes-related blindness.…”
Get full text
Article -
222
Complications of Macular Peeling
Published 2015-01-01“…Macular peeling refers to the surgical technique for the removal of preretinal tissue or the internal limiting membrane (ILM) in the macula for several retinal disorders, ranging from epiretinal membranes (primary or secondary to diabetic retinopathy, retinal detachment…) to full-thickness macular holes, macular edema, foveal retinoschisis, and others. …”
Get full text
Article -
223
Nonsteroidal Anti-Inflammatory Drugs for Retinal Disease
Published 2013-01-01“…For example, therapeutic effects on diabetic retinopathy and age-related macular degeneration may now be achievable. …”
Get full text
Article -
224
Dissecting Causal Relationships Between Antihypertensive Drug, Gut Microbiota, and Type 2 Diabetes Mellitus and Its Complications: A Mendelian Randomization Study
Published 2025-01-01“…., Pinacidil) gene expression was associated with lower SBP of 1.12 (95% confidence interval [CI], 0.93–1.31) mmHg, and a decreased risk of diabetic retinopathy (odds ratio [OR], 0.63; 95% CI, 0.52–0.76). …”
Get full text
Article -
225
Temporal Approach, Digitally Assisted Phacovitrectomy in a Patient with Severe Kyphosis due to Axial Spondyloarthritis
Published 2021-01-01“…A 70-year-old male patient with proliferative diabetic retinopathy with vitreous hemorrhage and cataract and ankylosing spondylitis with severe kyphosis. …”
Get full text
Article -
226
Retinopathy Diabetic Recognition and Detection Using Novel Intelligent Algorithms
Published 2023-06-01“…We propose a novel approach utilizing hybrid methods for diabetic retinopathy recognition and detection. The proposed approach consists of four levels: pre-processing for noise removal and standardization of the input dataset, image segmentation using Spiking Neural Network (SNN) based on edge detection, dimension reduction and feature selection using percolation theory, and the final step of combining SNN and percolation theory for retinopathy area detection. …”
Get full text
Article -
227
Novel indicator of microvascular complications in patients with type 2 diabetes mellitus and shortened erythrocyte lifespan: a multicenter cross-sectional analysis
Published 2025-01-01“…Methods This study encompassed individuals from the Tianjin Diabetic Retinopathy Screening Cohort who completed continuous glucose monitoring and had an erythrocyte lifespan of under 90 days. …”
Get full text
Article -
228
Examining the Choroid in Ocular Inflammation: A Focus on Enhanced Depth Imaging
Published 2014-01-01“…The choroid is the vascular layer that supplies the outer retina and is involved in the pathogenesis of several ocular conditions including choroidal tumors, age related macular degeneration, central serous chorioretinopathy, diabetic retinopathy, and uveitis. Nevertheless, difficulties in the visualization of the choroid have limited our understanding of its exact role in ocular pathology. …”
Get full text
Article -
229
A Systematic Review of Deep Learning Methods Applied to Ocular Images
Published 2019-11-01“…On the one hand, these methods have achieved an outstanding performance in the detection of ocular diseases such as: diabetic retinopathy, glaucoma, diabetic macular degeneration and age-related macular degeneration. …”
Get full text
Article -
230
MicroRNAs in Postischemic Vascular Repair
Published 2012-01-01“…In adulthood, angiogenesis is activated as a reparative process during wound healing and following ischemia, and it plays a key role in tumor growth and metastasis as well as in inflammatory diseases and diabetic retinopathy. MicroRNAs (miRNAs) are endogenous, small, noncoding RNAs that negatively control gene expression of target mRNAs. …”
Get full text
Article -
231
Does Fundus Fluorescein Angiography Procedure Affect Ocular Pulse Amplitude?
Published 2013-01-01“…Sixty eyes of 30 nonproliferative diabetic retinopathy patients (15 males, 15 females) were included in this cross-sectional case series. …”
Get full text
Article -
232
Adropin as an indicator of T2DM and its complications
Published 2022-11-01“…In this article, the underlying mechanisms of adropin for regulating obesity, T2DM and its complications including diabetic nephropathy, diabetic retinopathy, diabetic encephalopathy, diabetic vascular disease and diabetic cardiovascular disease were summarized. …”
Get full text
Article -
233
Development of Anti-VEGF Therapies for Intraocular Use: A Guide for Clinicians
Published 2012-01-01“…As a result, several groups targeted this molecule as a potential mediator of retinal ischemia-induced neovascularization in disorders such as diabetic retinopathy and retinal vein occlusion. Around this time, it also became clear that increased intraocular VEGF production was not limited to ischemic retinal diseases but was also a feature of choroidal vascular diseases such as neovascular age-related macular degeneration (AMD). …”
Get full text
Article -
234
Optimising deep learning models for ophthalmological disorder classification
Published 2025-01-01“…Disorders such as hypertension, glaucoma, and diabetic retinopathy are indicated by structural alterations in the optic disc, blood vessels, fovea, and macula. …”
Get full text
Article -
235
Combination of Anti-VEGF and Laser Photocoagulation for Diabetic Macular Edema: A Review
Published 2017-01-01“…Thirty years ago, the Early Treatment Diabetic Retinopathy Study (ETDRS) demonstrated that focal/grid laser photocoagulation reduces moderate vision loss from DME by 50% or more; thus, macular photocoagulation became the gold standard treatment for DME. …”
Get full text
Article -
236
Anti-VEGF Agents for Ocular Angiogenesis and Vascular Permeability
Published 2012-01-01“…IVB has also been reported to be effective for inducing the regression of new vessels in proliferative diabetic retinopathy. The use of bevacizumab in stage 4 or 5 retinopahty of permaturity (ROP) is to reduce the plus sign to help reduce hemorrhage during the subsequent vitrectomy. …”
Get full text
Article -
237
The PI3K/Akt Signaling Pathway Mediates the High Glucose-Induced Expression of Extracellular Matrix Molecules in Human Retinal Pigment Epithelial Cells
Published 2015-01-01“…Prolonged hyperglycemia is an important risk factor of the pathogenesis of diabetic retinopathy (DR). Extracellular matrix molecules, such as fibronectin, collagen IV, and laminin, are associated with fibrotic membranes. …”
Get full text
Article -
238
Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice
Published 2017-01-01“…Loss of pericytes, an early hallmark of diabetic retinopathy (DR), results in breakdown of the blood-retinal barrier. …”
Get full text
Article -
239
A Computational Model of Peripheral Photocoagulation for the Prevention of Progressive Diabetic Capillary Occlusion
Published 2016-01-01“…We developed a computational model of the propagation of retinal ischemia in diabetic retinopathy and analyzed the consequences of various patterns and sizes of burns in peripheral retinal photocoagulation. …”
Get full text
Article -
240
Administration of Traditional Chinese Blood Circulation Activating Drugs for Microvascular Complications in Patients with Type 2 Diabetes Mellitus
Published 2016-01-01“…Here, we reviewed the scientific evidence underpinning the use of blood circulation activating drugs to prevent and treat DM-induced microvascular complications, including diabetic nephropathy (DN), diabetic peripheral neuropathy (DPN), and diabetic retinopathy (DR). Furthermore, we summarized the effects and mechanism of TCM on improving blood rheology, inhibiting aggregation of platelet, forming advanced glycation end products (AGEs), regulating oxidative stress, reducing blood fat, and improving lipid metabolism. …”
Get full text
Article