Triglyceride-independent associations between circulating levels of apolipoprotein C-III and biomarkers of inflammation by Dídac Llop, Pere Rehues, Silvia Paredes, Montse Guardiola, Josefa Girona, Roser Rosales, Yaiza Esteban, Lluís Masana, Daiana Ibarretxe, Joan-Carles Vallvé, Josep Ribalta

“…Methods This cross-sectional study involved 1242 participants: 906 patients with MD (metabolic syndrome, type 2 diabetes (T2DM) and/or obesity), 192 patients with RA, and 144 controls. …”
Get full text

Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine by Farhang H. Awlqadr, Kithar Rasheed Majeed, Ammar B. Altemimi, Arkan Mohammed Hassan, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Alaa Jabbar Abd Al‐Manhel, Mazin A.A. Najm, Efstathia Tsakali, Jan F.M. Van Impe, Ahmed A. Abd El-Maksoud, Tarek Gamal Abedelmaksoud

“…Enhanced drug solubility, distribution to the site of interest, and successful therapeutic outcomes have had a major impact on inflammatory disorders, cardiovascular diseases, diabetes, skin problems, and neurodegenerative diseases. …”
Get full text

Association of Irisin with Fat Mass, Resting Energy Expenditure, and Daily Activity in Conditions of Extreme Body Mass Index by María Pardo, Ana B. Crujeiras, María Amil, Zaida Aguera, Susana Jiménez-Murcia, Rosa Baños, Cristina Botella, Rafael de la Torre, Xavier Estivill, Ana B. Fagundo, Jose M. Fernández-Real, José C. Fernández-García, Gema Fruhbeck, Javier Gómez-Ambrosi, Roser Rodríguez, Francisco J. Tinahones, Fernando Fernández-Aranda, Felipe F. Casanueva

“…FNDC5/irisin has been recently postulated as beneficial in the treatment of obesity and diabetes because it is induced in muscle by exercise, increasing energy expenditure. …”
Get full text

Ginsenoside F1 administration promotes UCP1-dependent fat browning and ameliorates obesity-associated insulin resistance by Yuhan Meng, Weili Li, Chenxing Hu, Si Chen, Haiyang Li, Feifei Bai, Lujuan Zheng, Ye Yuan, Yuying Fan, Yifa Zhou

“…Obesity-induced type 2 diabetes is mainly due to excessive free fatty acids leading to insulin resistance. …”
Get full text

Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes by Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono

“…Background Metformin (Met) is the first-line treatment for type 2 diabetes mellitus and plays an effective role in treating various diseases, such as cardiovascular disease, neurodegenerative disease, cancer, and aging. …”
Get full text

Clinical Characteristics, Laboratory Parameters, and Molecular Epidemiology of Neuroinvasive Flavivirus Infections in a Hotspot Region of Eastern Croatia by Dario Sabadi, Kristian Bodulić, Vladimir Savić, Nika Vlahović Vlašić, Maja Bogdanić, Ljiljana Perić, Irena Tabain, Dubravka Lišnjić, Mario Duvnjak, Snježana Židovec-Lepej, Barbara Grubišić, Ilija Rubil, Ljubo Barbić, Luka Švitek, Vladimir Stevanović, Petra Smajić, Bernarda Berišić, Mihaela Zlosa, Ivana Rončević, Tatjana Vilibić-Čavlek

“…Comorbidities were more frequently detected in WNV patients (hypertension 56.3 vs. 18.2%; diabetes 31.3 vs. 0%). Meningitis was the most common clinical presentation in both TBE and WNV neuroinvasive disease (WNND; 63.6 and 59.4%, respectively). …”
Get full text

Short-term abstinence from alcohol and changes in cardiovascular risk factors, liver function tests and cancer-related growth factors: a prospective observational study by Gautam Mehta, Rajiv Jalan, Matteo Rosselli, James Maurice, Stewart Macdonald, Alexandra Cronberg, Tanya Khera-Butler, Colin Sumpter, Safa Al-Khatib, Anjly Jain, Christos Charalambous, Amir Gander, Cynthia Ju, Talay Hakan, Roy Sherwood, Devaki Nair, Kevin P Moore

“…These data support an independent association of alcohol consumption with cancer risk, and suggest an increased risk of metabolic diseases such as type 2 diabetes and fatty liver disease.…”
Get full text

Low Expression of FFAR2 in Peripheral White Blood Cells May Be a Genetic Marker for Early Diagnosis of Acute Myocardial Infarction by Jianjun Ruan, Heyu Meng, Xue Wang, Weiwei Chen, Xiaomin Tian, Fanbo Meng

“…Logistic regression analysis suggested that the low expression of the FFAR2 gene in peripheral blood may be a risk factor for AMI independent of age, family history of diabetes, fasting blood glucose level, and HDL-C level (p=0.025). …”
Get full text

Evaluation of Yield and Yield Components of Different Ecotypes of Black Cumin (Nigella sativa L.) to Planting Date in Gorgan by Mohammad Sadeq Ashrafi, Farshid Ghaderi-Far, Elias Soltani, Ebrahim Zeinali, Asieh Siahmarguee

“….), often referred to as a "miracle herb," is a medicinal plant that has been used worldwide for centuries in the treatment and prevention of diseases such as cancer and diabetes. Additionally, it has been valued as a spice and flavoring agent in products like bread and sweets. …”
Get full text

Association between interpregnancy interval and adverse perinatal outcomes according to maternal age in the context of China’s two-child policy by SiQin Xiu, Li Tang, Chengjie Qin, Di Tian, Yuhong Chen, Lingling Gu, Liu Yang, Yuhao Sun, Xinghui Liu, Yonghong Lin, Yumei Wang

“…Results Women with longer IPIs (≥ 120 months) were more likely to be older (≥ 35 years) and had higher rates of gestational diabetes and hypertensive disorders of pregnancy (p < 0.05). …”
Get full text

Sucrose-preferring gut microbes prevent host obesity by producing exopolysaccharides by Hidenori Shimizu, Junki Miyamoto, Keiko Hisa, Ryuji Ohue-Kitano, Hiromi Takada, Mayu Yamano, Akari Nishida, Daiki Sasahara, Yuki Masujima, Keita Watanabe, Shota Nishikawa, Sakura Takahashi, Takako Ikeda, Yuya Nakajima, Naofumi Yoshida, Chiaki Matsuzaki, Takuya Kageyama, Ibuki Hayashi, Akari Matsuki, Ryo Akashi, Seiichi Kitahama, Masako Ueyama, Takumi Murakami, Shinsuke Inuki, Junichiro Irie, Noriko Satoh-Asahara, Hirokazu Toju, Hiroshi Mori, Shinji Nakaoka, Tomoya Yamashita, Atsushi Toyoda, Kenji Yamamoto, Hiroaki Ohno, Takane Katayama, Hiroshi Itoh, Ikuo Kimura

Get full text

Disability, comorbidities and risk determinants at end of TB treatment in Kenya, Uganda, Zambia and Zimbabwe by The Kenya, Uganda, Zambia, and Zimbabwe TB Disability Study Group (members listed here in alphabetical order):, S.A. Adakun, F.M. Banda, A. Bloom, M. Bochnowicz, J. Chakaya, A. Chansa, H. Chiguvare, R. Chimzizi, C. Colvin, J.P. Dongo, A. Durena, C. Duri, R. Edmund, A.D. Harries, I. Kathure, F.N. Kavenga, Y. Lin, H. Luzze, I. Mbithi, M. Mputu, A. Mubanga, D. Nair, M. Ngwenya, B. Okotu, P. Owiti, A. Owuor, P. Thekkur, C. Timire, S. Turyahabwe, E. Tweyongyere, M. YaDiul, R. Zachariah, K. Zimba

“…For comorbidities, 476 (44%) had HIV co-infection, 172 (16%) had high blood pressure (newly detected in 124), 43 (4%) had mental health disorders (newly detected in 33) and 36 (3%) had diabetes mellitus. The most common risk determinants were ‘probable alcohol dependence’ (15%) and malnutrition (14%). …”
Get full text

Syncopes and clinical outcome in heart failure: results from prospective clinical study data in Germany by Djawid Hashemi, Moritz Blum, Meinhard Mende, Stefan Störk, Christiane E. Angermann, Sabine Pankuweit, Elvis Tahirovic, Rolf Wachter, Burkert Pieske, Frank Edelmann, Hans‐Dirk Düngen, the German Competence Network for Heart Failure

“…Further analyses showed that among patients with HFrEF with HoS, known cardiovascular risk factors (e.g. age, male sex, diabetes mellitus, and anaemia) were more prevalent. …”
Get full text

The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome by Sydora BC, Wilke MS, Ghosh M, Vine DF

“…PCOS is associated with an increased risk of infertility, pregnancy complications, obesity, type 2 diabetes, cardiovascular diseases, and mental health disorders such as anxiety, depression, and negative self-image. …”
Get full text

Definitional differences in “outpatient” surgery can influence study outcomes related to total shoulder arthroplasty by Junho Song, MD, Jennifer Yu, BS, Avanish Yendluri, BS, William A. Ranson, MD, Nikan K. Namiri, MD, John J. Corvi, MD, David E. Kantrowitz, MD, Thomas Boucher, MD, Leesa M. Galatz, MD, Paul J. Cagle, MD, Bradford O. Parsons, MD, Robert L. Parisien, MD

“…Compared to SDD, HDO was associated with female sex, higher body mass index, functional dependence, diabetes, chronic obstructive pulmonary disease, congestive heart failure, hypertension, American Society of Anesthesiologists ≥3, longer operation time, and nonhome discharge. …”
Get full text

Liver Elastography for Liver Fibrosis Stratification: A Comparison of Three Techniques in a Biopsy-Controlled MASLD Cohort by Antonio Liguori, Giorgio Esposto, Maria Elena Ainora, Irene Mignini, Raffaele Borriello, Linda Galasso, Mattia Paratore, Maria Cristina Giustiniani, Laura Riccardi, Matteo Garcovich, Antonio Gasbarrini, Luca Miele, Maria Assunta Zocco

“…At multivariate regression analysis, S-Shearwave Imaging was associated with advanced fibrosis (≥F3) independently from age, diabetes and platelets (OR 2.94, CI 1.69–5.11, <i>p</i> < 0.01). …”
Get full text

Early risk assessment in paediatric and adult household contacts of confirmed tuberculosis cases by novel diagnostic tests (ERASE-TB): protocol for a prospective, non-interventiona... by Ursula Panzner, Katharina Kranzer, Tsitsi Bandason, Kuda Mutasa, Sandra Rukobo, Charles Sandy, Bariki Mtafya, Andrea Rachow, Norbert Heinrich, Michael Hoelscher, Judith Bruchfeld, Olena Ivanova, Nyanda Elias Ntinginya, Doreen Pamba, Laura Olbrich, Issa Sabi, Simeon Mwanyonga, Elmar Saathoff, Willyhelmina Olomi, Junior Mutsvangwa, Hazel M Dockrell, Edson Tawanda Marambire, Denise Banze, Alfred Mfinanga, Theodora D Mbunda, Khosa Celso, Gunilla Kallenius, Claire J Calderwood, Christof Geldmacher, Kathrin Held, Tejaswi Appalarowthu, Friedrich Rieß, Anna Shepherd, Christopher Sundling, Mishelle Mugava, Martha Chipinduro, Lwitiho Sudi, Antelmo Haule, Emmanuel Sichone, Paschal Qwaray, Harrieth Mwambola, Lilian Minja, Peter Edwin, Dogo Ngalison, Stella Luswema, Celina Nhamuave, António Machiana, Carla Madeira, Emelva Manhiça, Nádia Sitoe, Jorge Ribeiro

“…At baseline, HHCs will also be screened for HIV, diabetes (HbA1c), chronic lung disease (spirometry), hypertension and anaemia. …”
Get full text

A study of relationship between cardiac exposure dose-volume and cardiovascular autonomic dysfunction in radiotherapy by CHEN Hongyu, SU Pengyu, LUO Wenzi, PANG Dequan, WANG Feiran

“…Exclusion criteria: ① previously received chest radiotherapy; ② patients with obvious palpitation, chest tightness and chest pain before treatment; ③ diabetes, heart disease and other serious underlying diseases; ④ anti-arrhythmic drugs are currently being used; ⑤ patients who cannot tolerate radiotherapy and who were lost or lost during follow-up. …”
Get full text

Epidemiology and Resistance Profiles of Bacteria Isolated From Blood Samples in Septic Patients at Emergency Department Admission: A 6-Year Single Centre Retrospective Analysis Fro... by Valeria Cento, Sara Carloni, Riccardo Sarti, Linda Bussini, Zian Asif, Paola Morelli, Francesco De Fazio, Federica Maria Tordato, Maddalena Casana, Debora Mondatore, Antonio Desai, Elena Generali, Nicola Pugliese, Elena Costantini, Massimo Vanoni, Maurizio Cecconi, Stefano Aliberti, Giorgio Da Rin, Erminia Casari, Michele Bartoletti, Antonio Voza

“…Clinical features included age, sex, comorbidities (e.g., cancer, diabetes), infection source, presence of central venous catheters (CVC), ongoing therapies, and sepsis severity. …”
Get full text

Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

“…Setting: Data on age, sex, race, alcohol consumption, smoking status and type 2 diabetes were collected at baseline interview. Previous and diagnosed cancer or diseases were collected from self-reported and in-hospital records. …”
Get full text