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Unsupervised machine learning clustering approach for hospitalized COVID-19 pneumonia patients
Published 2025-02-01“…Cluster 3 (N = 141) was characterized by older age, diabetes mellitus, higher chest x-ray scores, more severe vital signs, higher creatinine levels, lower hemoglobin levels, lower lymphocyte counts, higher C-reactive protein, higher D-dimer, and higher LDH levels. …”
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7763
The relevance of a multidomain geriatric assessment in older patients with heart failure
Published 2020-06-01“…Logistic regression analyses adjusted for age, sex, diabetes and kidney function assessed 3 month risk of adverse health outcomes (emergency department visits, hospital admissions, and/or death) according to HF severity, physical frailty, and number of affected domains. …”
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7764
The impact of weight loss interventions on disordered eating symptoms in people with overweight and obesity: a systematic review & meta-analysisResearch in context
Published 2025-02-01“…Funding: Novo Nordisk UK Research Foundation Doctoral Fellowship in Clinical Diabetes.…”
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7765
Elevated Circulating Adipocyte-Fatty Acid Binding Protein Levels Predict Incident Ischemic Cardiovascular Events in a Longitudinal and Prospective AMI Aging Study
Published 2025-02-01“…Initially, participants were stratified into three groups according to the tertile levels of FABP4, followed by further categorization based on various lipid profiles and specific inflammatory markers.Results: On follow-up (median 751 days, maximum 1506 days), a total of 158 ischemic events were recorded. 1) In multivariable models meticulously adjusted for age, gender, traditional coronary heart disease factors, Killip classification, and discharge medications, the association of elevated levels of FABP4 (Tertile 3 HR 1.618 [1.061 to 2.468], p=0.026), augmented concentrations of PTX3 (Tertile 3 HR 1.811 [1.211 to 2.710], p=0.004), or LL-37 (Tertile 3 HR 0.651 [0.433 to 0.981], p=0.040) with ischemic risk was markedly intensified. 2) Multivariate HRs associated with 1 standard deviation (SD) (mg/dL) increase in the FABP4 parameters were as follows in different subgroups. 1-SD difference in FABP4 was associated with a 23%, 23%, 21 and 29% increase in ischemic events over after fully adjusted the confounding risk factors among male, patients with hyperlipidemia, hypertension and diabetes respectively. 3) The Kaplan-Meier curve demonstrated significant differences between the tertiles of FABP4 index levels among all enrolled participants (p=0.0180).Conclusion: This study reinforces the utility of FABP4 for enhancing risk stratification specifically among older patients diagnosed with ST-elevation myocardial infarction.Keywords: FABP4, lipid profile, PTX3, LL-37, ischemic vascular events…”
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7766
The Effect of Combining mHealth and Health Professional–Led Intervention for Improving Health-Related Outcomes in Chronic Diseases: Systematic Review and Meta-Analysis
Published 2025-01-01“… BackgroundChronic diseases such as diabetes and cardiovascular disease are global health challenges, affecting millions of people worldwide. …”
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7767
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7768
Bariatric surgery in elderly patients
Published 2024-12-01“…The remission of type 2 diabetes was achieved in 70.6% of the patients of the older age group. …”
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7769
Bacterial Profiles and Antibiotic Resistance in Chronic Obstructive Pulmonary Disease Patients with Exacerbation and Type 2 Respiratory Failure at Adam Malik General Hospital
Published 2024-09-01“…It was shown that severe exacerbations were prevalent (92%), accompanied by the presence of common comorbidities including pneumonia (52%), diabetes mellitus (32%), and other non-communicable diseases (44%). …”
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7770
Comparing International Guidelines for the Remission of Hypertension After Bariatric Surgery
Published 2025-01-01“…Background/Objectives: Obesity remains a global health concern and is associated with increased risk of type 2 diabetes, hypertension, and cardiovascular disease overall. …”
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7771
A comprehensive review on the plant sources, pharmacological activities and pharmacokinetic characteristics of Syringaresinol
Published 2025-02-01“…These pharmacological properties lay the foundation for its use in treating various diseases such as inflammatory diseases, neurodegenerative disorders, diabetes and its complication, skin disorders, cancer, cardiovascular, and cerebrovascular diseases. …”
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7772
Prevalence, Patterns and Factors Associated with Dyslipidemia Among Adult Hypertensive Patients
Published 2024-12-01“…Additionally, dyslipidemia was 1.414 times more common (aOR = 1.414, CI = 1.280-1.561, P < 0.001) among current or former smokers and 1.493 times more common (aOR = 1.493, CI = 1.372-1.625, P < 0.001) in patients with diabetes mellitus. The findings highlight a high prevalence of dyslipidemia, emphasizing the need for targeted interventions. …”
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7773
Impaired pulmonary function increases the risk of gout: evidence from a large cohort study in the UK Biobank
Published 2024-12-01“…Subgroup analysis revealed significant interactions between impaired pulmonary function and several factors, including body mass index (BMI), levels of physical activity, and diabetes status, in their associations with the risk of gout. …”
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7774
Biologic Therapy and Cardiometabolic Risk in Psoriasis: A Retrospective Review
Published 2025-01-01“…Abstract Introduction Psoriasis is a systemic inflammatory disease with increased cardiometabolic risk including dyslipidaemia and diabetes. Biologic therapy effectively treats the cutaneous inflammatory burden of psoriasis and evolving evidence suggests potential to reduce systemic inflammatory sequalae that can elevate cardiovascular risk. …”
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7775
Left ventricular remodeling and its association with mineral and bone disorder in kidney transplant recipients
Published 2024-12-01“…Advanced age, increased BMI, diabetes, longer dialysis time, lower albumin level, and higher total cholesterol and low-density lipoprotein levels were associated with LV remodeling.Conclusions LV remodeling partially improved after KT, showing a close relationship with MBD.…”
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7776
Metabolic Alterations in Different Stages of Hypertension in an Apparently Healthy Nigerian Population
Published 2013-01-01“…MS components and other CVD risk measures were investigated in different stages of hypertension. 534 apparently healthy Nigerian traders aged 18–105 years were participants of a cohort study. The International Diabetes Federation (2005) and the National High Blood Pressure Education Program Coordinating Committee criteria were used for MS and HTN classifications, respectively. …”
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7777
Optical Coherence Tomography Guided Intravascular Lithotripsy in the Peripheral Vasculature: Technique and Case Series Analysis
Published 2024-12-01“…The comorbidities present in the cohort were diabetes mellitus II, coronary artery disease, dyslipidemia, and hypertension were observed in 21 (87.5%), 20 (83.3%), 17 (70.8%), and 14 (58.3%) patients, respectively. …”
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7778
Polyunsaturated Fatty Acids and Human Health: A Key to Modern Nutritional Balance in Association with Polyphenolic Compounds from Food Sources
Published 2024-12-01“…Modern diets like the Western diet and the American diet are rich in saturated fats found especially in fast food products, sweets, and processed foods, a fact that has led to an increase in the prevalence of metabolic diseases worldwide (obesity, type II diabetes, gout, cardiovascular disease). Nutritionists have drawn attention to the moderate consumption of saturated fats and the need to increase the intake of unsaturated fats to the detriment of saturated ones. …”
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7779
Increased DHEAS and Decreased Total Testosterone Serum Levels in a Subset of Men with Early-Onset Androgenetic Alopecia: Does a Male PCOS-Equivalent Exist?
Published 2020-01-01“…It has been suggested that a male polycystic ovarian syndrome- (PCOS-) equivalent, defined as an endocrine syndrome with a metabolic background and a PCOS-like hormonal pattern, predisposing to type II diabetes mellitus (DM II), cardiovascular and prostate diseases later in life, may occur in at least a part of these men. …”
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7780
The association between periodontal disease and adverse pregnancy outcomes: a bibliometric analysis from 2000 to 2023
Published 2025-01-01“…Adverse pregnancy outcomes (APOs), including preterm birth, small for gestational age infants, gestational diabetes and preeclampsia, are linked to pregnancy complications. …”
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