Prolonged pain-to-balloon time still impairs midterm left ventricular function following STEMI by Dominik Felbel, Sabrina Fackler, Rachel Michalke, Michael Paukovitsch, Matthias Gröger, Mirjam Keßler, Nicoleta Nita, Yannick Teumer, Leonhard Schneider, Armin Imhof, Dominik Buckert, Wolfgang Rottbauer, Sinisa Markovic

“…Mean age was 63 ± 12 years, 75% were male, 14% had diabetes, 72% had arterial hypertension, and 56% had history of smoking. …”
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Dietary habits and weight change during the second wave of the COVID-19 pandemic among the Egyptian population by Samar Abd ElHafeez, Yasmine Amr Issa, Samar Tharwat, Ahmed Yahia Elmowafy, Karem Mohamed Salem, Noha Gaber Amin, Mohammed Kamal Nassar, Ramy Ghazy Mohamed

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Prevalence of Hypertension and Associated Factors in Lubumbashi City, Democratic Republic of Congo: A Community-Based Cross-Sectional Study by Jacques Mbaz Musung, Placide Kambola Kakoma, Clarence Kaut Mukeng, Stéphane Lubamba Tshimanga, Jeef Paul Munkemena Banze, Nathalie Kayomb Kaj, Martin Kazadi Kamuna, Jimmy Kasali Mwamba, Dophra Ngoy Nkulu, Philippe Bianga Katchunga, Olivier Mukuku, Emmanuel Kiyana Muyumba

“…After logistic regression, the risk of hypertension increased with age >50 years (aOR = 5.85 [5.19–6.60]), overweight (aOR = 1.25 [1.11–1.41]), obesity (aOR = 1.25 [1.11–1.41]), central obesity (aOR = 1.37 [1.16–1.61]), diabetes mellitus (aOR = 2.19 [1.63–2.95]), alcohol consumption (aOR = 1.21 [1.05–1.39]), nonconsumption of vegetables (aOR = 1.35 [1.02–1.80]), and history of stroke (aOR = 2.57 [1.88–3.51]). …”
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Doctor, what is my risk of bleeding after cardiac surgery while on combined anticoagulant with antiplatelet therapy? A validated nomogram for risk assessment by Haolong Han, Haolong Han, Hang Xu, Hang Xu, Jifan Zhang, Weihui Zhang, Yi Yang, Xia Wang, Li Wang, Dongjin Wang, Weihong Ge

“…Various models were developed, validated and evaluated by using methods including ROC curves, calibration curves, the Hosmer-Lemeshow test, net reclassification improvement (NRI), integrated discrimination improvement (IDI) index, decision curve analysis (DCA) and clinical impact curves (CIC).ResultsMod2 showed the best performance (AUC of validation set = 0.863) which consists of 8 independent predictive factors (gender, age > 65 years, diabetes, anemia, atrial fibrillation, cardiopulmonary bypass time, intraoperative bleeding and postoperative drainage), with a significantly higher AUC compared to Mod1 (only preoperative factors) and Mod3 (the HAS-BLED scoring model). …”
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Pulse Pressure Relationships with Demographics and Kidney Function in Ashanti, Ghana by Debasish Banerjee, Jacob Plange-Rhule, Nihil Chitalia, Kwabena Kumi, Frank B. Micah, Francesco P. Cappuccio, John B. Eastwood

“…The demographic and clinical characteristics were: age 55(11) [mean (SD)] years, females 62%, rural village-dwellers 52%, diabetes 1·5%, BMI 21(4) kg/m2, 24-hourCrCl as a measure of glomerular filtration rate (GFR) 84(23) ml/min/1.73 m2. 29% had BP >140/90 mmHg; SBP and DBP were 125/74(26/14) mmHg, PP was 51(17) mmHg. …”
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AbaComplex Enhances Mitochondrial Biogenesis and Adipose Tissue Browning: Implications for Obesity and Glucose Regulation by Serena Sagliocchi, Elisabetta Schiano, Lucia Acampora, Fortuna Iannuzzo, Annunziata Gaetana Cicatiello, Caterina Miro, Annarita Nappi, Federica Restolfer, Mariano Stornaiuolo, Stefano Zarrilli, Fabrizia Guerra, Gian Carlo Tenore, Monica Dentice, Ettore Novellino

“…Excess WAT, especially visceral fat, is strongly linked to metabolic disorders such as obesity and type 2 diabetes. The browning of WAT, whereby white fat cells acquire characteristics of brown adipose tissue (BAT) with enhanced thermogenic capacity, represents a promising strategy to enhance metabolic health. …”
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evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomat... by Jeffrey L. Cummings, Alireza Atri, Howard H. Feldman, Oskar Hansson, Mary Sano, Filip K. Knop, Peter Johannsen, Teresa León, Philip Scheltens

“…The glucagon-like peptide-1 receptor agonist semaglutide is approved for the treatment of type 2 diabetes and obesity and has an established safety profile. …”
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Resultados da Intervenção Coronariana Percutânea Recomendada pelas Diretrizes em Mulheres com Doença Arterial Coronariana Obstrutiva: um Estudo de Coorte Longitudinal by Tacianne Rolemberg Braga Delamain, José Henrique Herrmann Delamain, Sergio Luiz Navarro Braga, Ricardo Costa, Dimytri Alexandre Alvim de Siqueira, Fausto Feres, Marinella Patrizia Centemero

“…Os fatores de risco foram frequentes (hipertensão: 88%, dislipidemia: 85%, diabetes: 47,5%) e 69% foram internadas devido à SCA. …”
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It is time to tackle psychological determinants of obesity and eating disorders by Pietro Crescenzo

“…Obesity and overweight constitute an important source of morbidity, impaired quality of life and mortality, as they are associated with several cancers, diabetes and cardiovascular diseases [5]. The worldwide prevalence of obesity nearly doubled between 1980 and 2008. …”
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UPLC-ESI-MS/MS Profile and Antioxidant, Cytotoxic, Antidiabetic, and Antiobesity Activities of the Aqueous Extracts of Three Different Hibiscus Species by Hanan M. Al-Yousef, Wafaa H. B. Hassan, Sahar Abdelaziz, Musarat Amina, Rasha Adel, May A. El-Sayed

“…It might be a natural alternative remedy and nutritional policy for diabetes and obesity treatment without negative side effects. …”
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The role of the estimated glomerular filtration rate and body roundness index in the risk assessment of uric acid-lowering therapy-resistant gout in U.S. adults: evidence from the... by Mengyuan Zhu, Xingqiang Wang, Zining Peng, Weitian Yan, Qian Deng, Meihui Li, Nian Liu, Ling Zhang

“…We explored the relationships of the eGFR, BRI, and VAI with UALT-RG risk via univariable and multivariable weighted logistic regression, trend analysis, and restricted cubic splines.Results Among the 1,811 patients with gout, ∼9.08% had UALT-RG; these patients were more likely to have obesity, comorbid diabetes (36% [27–47%] vs. 25% [22–28%]) or impaired kidney function (eGFR < 60 mL/min/1.73 m2, 34.5% [27–43%] vs. 22.5% [20–26%]); be former smokers; and take colchicine (10% [5.6–19%] vs. 4.3% [2.8–6.7%]). …”
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Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue by Sara Nava, Valeria Sordi, Luisa Pascucci, Carlo Tremolada, Emilio Ciusani, Offer Zeira, Moris Cadei, Gianni Soldati, Augusto Pessina, Eugenio Parati, Mark Slevin, Giulio Alessandri

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Metabolic dysfunction-associated fatty liver disease and risk of nephrolithiasis: a sizeable cross-sectional study by Shengqi Zheng, Tianchi Hua, Guicao Yin, Wei Zhang, Xiaoxiang Wang, Lezhong Qi, Xiayong Jing, Qibing Fan, Xiaoping Yu, Yifan Li

“…Subgroup analyses indicated that, even after accounting for various factors such as age, diabetes, hypertension, obesity, lipid profiles, and renal function, the positive association between MAFLD and an increased risk of nephrolithiasis remained consistent. …”
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Investigation of the physicochemical factors affecting the in vitro digestion and glycemic indices of indigenous indica rice cultivars by Indira Govindaraju, Anusha R. Das, Ishita Chakraborty, Sib Sankar Mal, Bhaswati Sarmah, Vishwa Jyoti Baruah, Nirmal Mazumder

“…Poor dietary choices have had a significant role in the development of type-2 diabetes in the population that relies on rice and rice-starch-based foods. …”
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Influence of the Expression of Inflammatory Markers on Kidney after Fetal Programming in an Experimental Model of Renal Failure by Carlos Donizete Pereira Júnior, Camila Souza de Oliveira Guimarães, Aline Cristina Souza da Silva, Aldo Rogelis Aquiles Rodrigues, Maria Aparecida da Glória, Vicente de Paula Antunes Teixeira, Niels Olsen Saraiva Câmara, Lenaldo Branco Rocha, Marlene Antônia dos Reis, Juliana Reis Machado, Laura Penna Rocha, Fernanda Rodrigues Helmo, Rosana Rosa Miranda Corrêa

“…The offspring aged two and five months were divided into four groups: CC (control dams, control offspring); DC (diabetic dams, control offspring); CFA (control dams, folic acid offspring, 250 mg/Kg); and DFA (diabetic dams, folic acid offspring). …”
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Fetal Growth Trajectories and Their Association with Maternal, Cord Blood, and 5-year Child Adipokines by H. C. Bartels, A. A. Geraghty, E. C. O’Brien, A. Kranidi, J. Mehegan, C. Yelverton, C. M. McDonnell, F. M. McAuliffe

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The association between monocyte to high-density lipoprotein cholesterol ratio and chronic kidney disease in a Chinese adult population: a cross-sectional study by Lingling Xu, Dongling Li, Zongwei Song, Jin Liu, Yang Zhou, Junwei Yang, Ping Wen

“…Similar conclusions were confirmed in subgroup analysis stratified by gender, age, BMI, central obesity, hypertension, and diabetes mellitus, after justification for confounding factors.Conclusion Elevated MHR level was independently associated with the presence of CKD, suggesting that it might serve as a useful clinical tool for risk stratification, offering valuable insights to inform preventive and therapeutic approaches for clinicians in their routine medical practice.…”
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Depression Paradox in Cardiovascular Outcomes of Adult Patients with Obstructive Sleep Apnea: Insights from 2 Million Nationwide Hospitalizations by Rupak Desai, Sashwath Srikanth, Shaylika Chauhan, Zainab Gandhi, Warda Shahnawaz, Aleen Rahman, Bisharah Rizvi, Akhil Jain

“…OSA+D+ cohort had a higher prevalence of hypertension, diabetes, hyperlipidemia, congestive heart failure, anemia, smoking, substance abuse, prior myocardial infarction (MI), transient ischemic attack (TIA), TIA/stroke, and venous thromboembolism than the OSA+D- group (all P < 0.001). …”
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The impact of solute carrier proteins on disrupting substance regulation in metabolic disorders: insights and clinical applications by Jiangxia Du, Minhui Shen, Jiajia Chen, Hao Yan, Zhifei Xu, Xiaochun Yang, Bo Yang, Bo Yang, Peihua Luo, Peihua Luo, Kefeng Ding, Yuhuai Hu, Qiaojun He, Qiaojun He, Qiaojun He, Qiaojun He

“…Dysregulation in the processes of absorption, transport, metabolism, and excretion of these metabolites can lead to the onset of severe metabolic disorders, such as type 2 diabetes, non-alcoholic fatty liver disease, gout and hyperbilirubinemia. …”
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High Concentration of Glucose Increases Reactive Oxygen Species Generation and Apoptosis Induced by Endoplasmic Reticulum Stress Pathway in Rabbit Corneal Epithelial Cells by Jiajun Lu, Minjie Sheng, Panpan Yao, Chaochao Ran, Hao Liu, Li Chen, Rui Liu, Bing Li

“…These results might provide theoretical basis for the study of the diabetes-related dry eye.…”
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