Reduced retinal microvascular density in women with coronary microvascular dysfunction: A pilot study by Sakshi Shiromani, Ahmed AlBadri, Aaron Lindeke-Myers, Arielle Schwartz, Nishant Vatsa, Esha Dave, Fauzia Rashid, Nieraj Jain, Puja K. Mehta

“…The CMD (N = 11) and non-CMD (N = 7) groups were balanced with respect to age, BMI, systemic diseases including diabetes, hypertension, and hyperlipidemia, and medications. …”
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The specificity of ten non-digestible carbohydrates to enhance butyrate-producing bacteria and butyrate production in vitro fermentation by Jingjing Xu, Ruyue Wang, Weibao Liu, Zhongwei Yin, Jianrong Wu, Xun Yu, Wen Wang, Hongtao Zhang, Zhitao Li, Minjie Gao, Li Zhu, Xiaobei Zhan

“…Ten non-digestible carbohydrates (NDCs), including inulin, fructooligosaccharide (FOS), oats β-glucans (OGS), oats β-glucan oligosaccharides (OGOS), Astragalus polysaccharides (APS), Astragalus oligosaccharides (AOS), xanthan gum oligosaccharides (XGOS), gellan gum oligosaccharides (GGOS), curdlan oligosaccharides (COS), and pullulan oligosaccharides (POS) were used to investigate NDC specificity in modulating butyrate-producing bacteria and butyrate production in 48-h in vitro fermentation studies in combination with fecal inocula from 7 healthy donors and 11 patients with type 2 diabetes (T2D). We observed that the amount of these ten NDCs utilized depended on NDC structure and inter-individual gut microbial differences. …”
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Caracterización clínico-epidemiológica de pacientes con un primer evento de fibrilación auricular by Víctor Manuel Regal Cuesta, Lázaro Enrique de la Cruz Avilés, Aymara Marcia Hernández Cardoso, Fransisco de Jesús Valladares Carvajal, Liz María Calvo Díaz, Milagros Lisset León Regal

“…Los antecedentes patológicos personales más frecuentes fueron: la hipertensión arterial (74,1 %), la diabetes mellitus tipo 2 (16,7 %) y las valvulopatías (11,1 %). …”
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Risk Estimation of Severe Primary Graft Dysfunction in Heart Transplant Recipients Using a Smartphone by Souhila Ait-Tigrine, Roger Hullin, Elsa Hoti, Matthias Kirsch, Piergiorgio Tozzi

“…Eleven risk factors were identified: female donors, female donor to male recipient, undersized donor, donor age, recipient on ventricular assist device support, recipient on amiodarone treatment, recipient with diabetes and renal dysfunction, re-sternotomy, graft ischemic time, and bypass time. …”
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Interaction effect between overweight/obesity and alcohol consumption on hypertension risk in China: a longitudinal study by Xiaoqin Wang, Zhaozhao Hui, Jiaru Sun, Paul D Terry, Xiaohan Ren, Shuangyan Lei, Caihua Wang, Mingxu Wang

“…After adjusting for age, gender, education level, marital status, physical activity, diabetes and smoking, high body mass index (BMI) and light drinking (OR=5.07, 95% CI 3.06 to 8.41), high waist circumference (WC) and light drinking (OR=4.81, 95% CI 2.92 to 7.91), high waist hip ratio and light drinking (OR=2.85, 95% CI 1.84 to 4.42) were the highest risk of all participants in the three combinations. …”
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Inverse relationship of oxidative balance score with hyperuricemia among Chinese adults: a population-based cross-sectional study by Hewei Peng, Ying Han, Jingru Huang, Wenxin Qiu, Huajing Chang, Jiangwang Fang, Xian-E Peng

“…There were significant interactions between OBS and gender, hypertension, and dyslipidemia on hyperuricemia (P interaction < 0.05), except for age, education, and diabetes (P interaction > 0.05). A linear dose-response relationship between OBS and the risk of hyperuricemia (P nonlinear = 0.7854) was observed. …”
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Development and internal validation of the Edmonton Obesity Staging System-2 Risk screening Tool (EOSS-2 Risk Tool) for weight-related health complications: a case-control study in... by Evan Atlantis, P Fahey, Kathryn Williams, Paul Dugdale, James Rufus John, SL Hocking, Kath Peters

“…Of 14 candidate risk factors, 6 (family history of diabetes, hypertension, high sugar in blood/urine, high cholesterol and self-reported bodily pain and disability) were automatically included based on definitional or obvious correlational criteria. …”
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Paradoxical Glucose-Sensitizing yet Proinflammatory Effects of Acute ASP Administration in Mice by Alexandre Fisette, Pegah Poursharifi, Katerina Oikonomopoulou, Mercedes N. Munkonda, Marc Lapointe, Katherine Cianflone

“…Acylation stimulating protein (ASP) is an adipokine derived from the immune complement system, which stimulates fat storage and is typically increased in obesity, type 2 diabetes, and cardiovascular disease. Using a diet-induced obesity (DIO) mouse model, the acute effects of ASP on energy metabolism and inflammatory processes in vivo were evaluated. …”
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Contemporary Results of Transcatheter Aortic Valve Replacement in Obese Patients by T. Owais, M. El Garhy, P. Lauten, M. Haensig, H. Lapp, P. C. Schulze, T. Kuntze

“…Obese patients showed statistically significant difference in their clinical parameters as having higher incidence of hypertension, diabetes mellitus, pulmonary hypertension, and chronic obstructive pulmonary disease; on the contrary, obese patients were found to be younger than others. …”
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Effect of trace elements and nutrients on 21 autoimmune diseases: a Mendelian randomization study by Ming-Jie Jia, Hua-Fang Yin, Ying-Chao Liang, Feng Jiang, Hui-Lin Li, Hui-Lin Li

“…Finally, trace elements and vitamins that were statistically significant in the IVW method and had consistent effect sizes and odds ratios across five methods were selected as exposure factors with a causal relationship to diabetes and its complications. Additionally, multivariable Mendelian randomization was employed to assess the combined effects of multiple exposure factors on autoimmune diseases.ResultsMR analysis indicated that elevated levels of the trace element copper were associated with an increased risk of systemic lupus erythematosus (SLE) and a decreased risk of ulcerative colitis. …”
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Dietary glycemic and insulin indices with the risk of osteoporosis: results from the Iranian teachers cohort study by Anahita HoushiarRad, Danial Fotros, Mina Esmaili, Mohammad Hassan Sohouli, Marjan Ajami, Morteza Abdollahi, Motahare Hatami Marbini

“…The participants had no history of diabetes, cardiovascular diseases, stroke, thrombosis, or cancer and consumed between 800 and 4,200 kcal/day. …”
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Incidence of SARS-CoV-2 reinfection in a paediatric cohort in Kuwait by Mohammad Alghounaim, Saadoun Bin-Hasan, Fatemah Alhaddad, Ali Abdulkareem, Danah Alsharrah, Abdullah Alkandari, Mona Al-Ahmad, Hashem Al Hashemi

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Experiencia en autopsias de fallecidos con la COVID-19 en el Hospital Militar Central “Dr. Luis Díaz Soto” by Teresita Montero González, José Hurtado de Mendoza Amat, Yusleidys Fraga Martínez, Liem Laguna Oliva, Leticia del Rosario Cruz, Yamile Torres Gómez

“…Las comorbilidades contribuyen a empeorar el pronóstico de estos fallecidos, con predominio de la hipertensión arterial y la diabetes mellitus. Las manifestaciones de la respuesta inflamatoria sistémica se presentan como complicaciones en ellos. …”
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The association between working hours and working type with non-alcoholic fatty liver disease: results from the NHANES 1999-2014 by Ruli Wang, Ningxi Wu, Huan Qu, Xiaowei Zheng, Haoyang Zhang, Lihong Zhu, Xiaolei Wang, Xiaodie Yao, Le Zhang

“…In addition, further subgroup analysis was performed based on sex, age, ratio of family income to poverty (PIR), education, and diabetes.ResultsLong working hours were significantly linked to an elevated risk of NAFLD (OR: 1.57, 95%CI: 1.21-2.05), even after controlling for confounding factors. …”
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Association between self-reported eye conditions in patients at rural federally qualified health centers and vision-targeted health-related quality of life: the AL-SIGHT study by Thomas A. Swain, Thomas A. Swain, Gerald McGwin, Gerald McGwin, Lindsay A. Rhodes, Christopher A. Girkin, Cynthia Owsley

“…We examined demographic factors and self-reported eye conditions associated with VFQ-9 scores.MethodsThe VFQ-9 (score range 0–100) was administered to patients at-risk for glaucoma including African Americans or Hispanics ≥40 years, white persons ≥50 years, persons with diabetes ≥18 years, ≥18 years with glaucoma or glaucoma suspect, and/or ≥ 18 years with a family history of glaucoma. …”
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Effectiveness of an Innovative Pulsed Electromagnetic Fields Stimulation in Healing of Untreatable Skin Ulcers in the Frail Elderly: Two Case Reports by Fabio Guerriero, Emanuele Botarelli, Gianni Mele, Lorenzo Polo, Daniele Zoncu, Paolo Renati, Carmelo Sgarlata, Marco Rollone, Giovannoi Ricevuti, Niccolò Maurizi, Matthew Francis, Mariangela Rondanelli, Simone Perna, Davide Guido, Piero Mannu

“…This case supports the supportive role for PEMFs in the treatment of skin ulceration in diabetes and is suggestive of a potential benefit of EBS in this clinical condition.…”
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Protocol for the systematic review of age and sex in preclinical models of age-correlated diseases [version 2; peer review: 2 approved] by Céline Heinl, Ines Schadock, Maximilian Wurm, Paul Lucas Wildner, Daniel Butzke, Bettina Bert, Alexandra Bannach-Brown, Matthias Steinfath, Kai Diederich

“…We compare the results with the age and sex of patients in clinical trials focusing on Alzheimer's disease, stroke, type 2 diabetes mellitus, ischemic heart disease, and chronic obstructive pulmonary disease. …”
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Analysis of the implementation value of abdominal B-ultrasound combined with cervical cerclage in the prevention and treatment of late recurrent spontaneous abortion by Lili Shi, Lei Dong, Yuanying Cui, Dan Bu, Bo Hu

“…The incidence of gestational hypertension, gestational diabetes mellitus, and eclampsia were significantly lower in the observation group compared to the control group (P < 0.05). …”
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Alu insertion polymorphisms and susceptibility to metabolic syndrome in a Moroccan population by Hamid Farhane, Majida Motrane, Karchali Soufaine, Fatima-Ezzahra Anaibar, Aïcha Motrane, Said Nassor Abeid, Abderraouf Hilali, Nourdin Harich

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Characterization of Active Compounds of Different Garlic (Allium sativum L.) Cultivars by Szychowski Konrad A., Rybczyńska-Tkaczyk Kamila, Gaweł-Bęben Katarzyna, Świeca Michał, Karaś Monika, Jakubczyk Anna, Matysiak Magdalena, Binduga Urszula E., Gmiński Jan

“…Garlic (Allium sativum L.) has a reputation as a therapeutic agent for many different diseases such as microbial infections, hypertension, hypercholesterolaemia, diabetes, atherosclerosis and cancer. Health benefits of garlic depend on its content of biologically-active compounds, which differs between cultivars and geographical regions. …”
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