Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activity by Lynn A. C. Devilée, Abou bakr M. Salama, Jessica M. Miller, Janice D. Reid, Qinghui Ou, Nourhan M. Baraka, Kamal Abou Farraj, Madiha Jamal, Yibing Nong, Todd K. Rosengart, Douglas Andres, Jonathan Satin, Tamer M. A. Mohamed, James E. Hudson, Riham R. E. Abouleisa

“…Furthermore, overexpression of Ras-related associated with Diabetes (RRAD), an endogenous inhibitor of LTCC, induced CM cell cycle activity in vitro, in human cardiac slices, and in vivo. …”
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Everolimus in Heart Transplantation: An Update by Stephan W. Hirt, Christoph Bara, Markus J. Barten, Tobias Deuse, Andreas O. Doesch, Ingo Kaczmarek, Uwe Schulz, Jörg Stypmann, Assad Haneya, Hans B. Lehmkuhl

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Improving influenza vaccine uptake in clinical risk groups: patient, provider and commissioner perspectives on the acceptability and feasibility of expanding delivery pathways in E... by Sandra Mounier-Jack, Rajeka Lazarus, Ben Kasstan, Ifra Ali

“…Phase I involved 32 semi-structured interviews conducted with individuals from three clinical risk groups: diabetes, chronic liver disease or chronic respiratory disease (or comorbidities). …”
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Risk factors of chronic kidney disease in cisplatin-based hyperthermia intraperitoneal chemotherapy by Chih-Chung Cheng, Hung-Chieh Yeh, Pei-Wen Su, Chien-Lin Ho, Sheng-Chi Chang

“…Multivariate regression analysis identified intraoperative use of parecoxib (Odds Ratio (OR) = 4.39) and intraoperative maximum temperature > 38.5°C (OR = 6.40) as major risk factors for cisplatin-based HIPEC-related CKD occurrence. Though type II diabetes mellitus and intraoperative complications were the independent risk factors of AKI following cisplatin-based HIPEC, but they were not shown in CKD analysis.Conclusion Intraoperative use of parecoxib during cisplatin-based HIPEC emerged as a significant risk factor for postoperative CKD. …”
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Acromegaly: Is earlier diagnosis possible? Exploration of a screening algorithm to select high-risk patients by Tessa N.A. Slagboom, David de Jong, Peter H. Bisschop, Madeleine L. Drent

“…After exploratory analysis and fine-tuning, an algorithm combining pathognomonic changes in clinical appearance with manifestations considered by medical experts to be most characteristic of acromegaly (hyperhidrosis, sleep apnoea, arthralgia, headache and type 2 diabetes mellitus) detected 48/90 of patients with previously diagnosed acromegaly, while identifying an additional 1844/1,7 million of possible at-risk patients. …”
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G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells by Jason M. Conley, Alexander Jochim, Carmella Evans-Molina, Val J. Watts, Hongxia Ren

“…Gut peptides, including glucagon-like peptide-1 (GLP-1), regulate metabolic homeostasis and have emerged as the basis for multiple state-of-the-art diabetes and obesity therapies. We previously showed that G protein-coupled receptor 17 (GPR17) is expressed in intestinal enteroendocrine cells (EECs) and modulates nutrient-induced GLP-1 secretion. …”
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Grounded theory assessment of health needs in rural Mississippi Delta region, USA: Implications for health policy and management by Yalanda M. BARNER, Austine U. ONYIA, Russell L. BENNETT, Manoj SHARMA

“…Participants identified hypertension, diabetes, mental health, and cancer as the most prevalent diseases. …”
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Evidence from NHANES 2011–2014: a correlation between the weight-adjusted-waist index and cognitive abilities in the United States by Chan Zhao, Xintian Xu, Chunyan Hao

“…We also executed subgroup analyses and interaction tests based on gender, race, educational background, marital status, diabetes, body mass index, alcohol consumption, hypertension, smoking habits, stroke, depression, and sleep quality to assess whether the relationship between WWI and cognitive function was affected by heterogeneity across different population segments. …”
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Prevalence, Awareness, Treatment, and Control of Hypertension among Saudi Adult Population: A National Survey by Abdalla A. Saeed, Nasser A. Al-Hamdan, Ahmed A. Bahnassy, Abdelshakour M. Abdalla, Mostafa A. F. Abbas, Lamiaa Z. Abuzaid

“…Significant predictors of hypertension included male gender, urbanization, low education, low physical activity, obesity, diabetes, and hypercholesterolemia. In conclusion prevalence is high, but awareness, treatment, and control levels are low indicating a need to develop a national program for prevention, early detection, and control of hypertension.…”
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Perfil clínico-epidemiológico de la COVID-19 en el municipio Cumanayagua. Cienfuegos, 2020 by Narciso Águila Rodríguez, Lourdes Elena Duany Badell, Midalys del Carmen LLanes Cartaya, Lázaro Roberto Herrera Fragoso, Eneida Bravo Polanco, Tamara Montenegro Castellón

“…La hipertensión arterial, la diabetes mellitus y la obesidad fueron las comorbilidades más frecuentes. …”
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Construction and validation of a nomogram predictive model for assessing the risk of surgical site infections following posterior lumbar fusion surgery by Jin-Zhou Luo, Jie-Zhao Lin, Qi-Fan Chen, Chang-Jian Yang, Chu-Song Zhou

“…Significant risk factors for SSIs included smoking history, diabetes, surgery duration ≥ 3 h, intraoperative blood loss ≥ 300 ml, ASA classification ≥ 3, postoperative closed drainage duration ≥ 5 days, incision length ≥ 10 cm, BMI ≥ 30 kg/m2, and the presence of internal fixation. …”
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FEATURES OF PREGNANCY, OBSTETRIC AND PERINATAL OUTCOMES DURING THE MANIFESTATION OF COVID-19 OF VARYING SEVERITY IN THE 1ST TRIMESTER OF GESTATION by Людмила Станиславовна Ищенко, Екатерина Евгеньевна Воропаева, Элла Алексеевна Казачкова, Евгений Леонидович Казачков, Татьяна Николаевна Шамаева, Елена Романовна Вейсенборн, Юлия Сергеевна Ищенко

“…In moderate cases of COVID-19, both during the period of manifestation and in convalescents, the incidence of diabetes mellitus that first developed during pregnancy increases statistically significantly. …”
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Utilizing physical educators to monitor muscular strength and neuromuscular control among children with varied recess time by G. Kate Webb, Yan Zhang, Deborah J. Rhea

“…Developing appropriate MusS during childhood decreases the chances of physical injuries and many chronic diseases such as type II diabetes and cancer, which leads to healthier, active future adults. …”
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Cardiovascular Risk Assessment: A Comparison of the Framingham, PROCAM, and DAD Equations in HIV-Infected Persons by Max Weyler Nery, Celina Maria Turchi Martelli, Erika Aparecida Silveira, Clarissa Alencar de Sousa, Marianne de Oliveira Falco, Aline de Cássia Oliveira de Castro, Jorge Tannus Esper, Luis Carlos Silva e Souza, Marília Dalva Turchi

“…The participants' mean age was 36.8 years (SD = 10.3), 76.9% were men, and 66.3% were on antiretroviral therapy. 47.8% of the participants had abdominal obesity, 23.1% were current smokers, 20.0% had hypertension, and 2.0% had diabetes. At least one lipid abnormality was detected in 72.8%, and a low HDL-C level was the most common. …”
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Real-world effectiveness and safety of sodium-glucose co-transporter 2 inhibitors in chronic kidney disease by Supattra Hunsuwan, Sarinya Boongird, Atiporn Ingsathit, Wanchana Ponthongmak, Nattawut Unwanatham, Gareth J McKay, John Attia, Ammarin Thakkinstian

“…These findings suggest SGLT2i therapy might reduce adverse kidney outcomes in CKD patients, regardless of diabetic status, with a favorable safety profile.…”
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Socioeconomic and behavioural factors that contribute to the co-occurrence of risk factors for noncommunicable diseases by Naftal Sakaria, Nelago Indongo

“…The results showed that overall, co-occurrence of risks was more prevalent among respondents with HBP than those with diabetes or HRD. Notably, age and education level positively contribute to co-occurrence of risk factors of NCDs. …”
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Educating patients about health helps slow the progression of chronic kidney disease in the eastern region of India by Supriya Dasgupta, Reeti Debnath

“…Additionally, a higher prevalence of co-existing conditions such as diabetes mellitus and hypertension was noted among CKD patients, along with documented instances of polycystic kidney disease, obstructive uropathy, and renal cell carcinoma. …”
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Breast reconstruction with deep inferior epigastric artery perforator flap (DIEP-flap). History of development by I. S. Duadze, A. D. Zikiryakhodzhaev, A. S. Sukhotko, M. V. Starkova, F. N. Usov, D. V. Bagdasarova, D. Sh. Dzhabrailova, Sh. G. Khakimova

“…Also, special attention is paid to the choice of breast reconstruction method depending on age, constitutional characteristics and the presence of risk factors such as smoking, diabetes mellitus and excess BMI. Analyzing the advantages of breast reconstruction with autograft flaps, the author concludes that there is a higher quality of life and improved outcomes in these patients than in patients who underwent implant-based reconstruction. …”
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Optimized scaffold-free human 3D adipose tissue organoid culture for obesity and disease modeling by Rafael Dariolli, Raphael Nir, Tova Mushlam, Glauco R. Souza, Stephen R. Farmer, Miguel L Batista, Jr.

“…Obesity and type 2 diabetes (T2D) are strongly linked to abnormal adipocyte metabolism and adipose tissue (AT) dysfunction. …”
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Translation and cross-cultural adaptation of the Get Active Questionnaire for Pregnancy (GAQ-P) to Spanish population by Eva Ferrer, Maia Brik, Margie Davenport, Ruben Barakat, Montse Palacio

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