Mutation yellow in agouti loci prevents age-related increase of skeletal muscle genes regulating free fatty acids oxidation by Y. V. Piskunova, A. Y. Kazantceva, A. V. Baklanov, N. M. Bazhan

“…The lethal yellow mutation in agouti loci (Ay mutation) reduces the activity of melanocortin (MC) receptors and causes hyperphagia, obesity and type two diabetes mellitus in aging mice (Ay mice). It is unknown if changes in distinct elements of the metabolic system such as white adipose tissue (WAT) and brown adipose tissue (BAT), and skeletal muscle will manifest before the development of obesity. …”
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A review on mechanisms of action of bioactive peptides against glucose intolerance and insulin resistance by Forough Jahandideh, Jianping Wu

“…Insulin resistance plays a key role in the pathophysiology of type 2 diabetes and metabolic syndrome. Reviews on the mechanisms of action of bioactive peptides on glucose homeostasis and insulin resistance are scarce. …”
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Caracterización clínica y tratamiento de pacientes con fibrilación auricular by Frank Miguel Hernández Velazquez, Shannon Elizabeth Carcasés Lamorú, Ramona Lamorú Turro, Alexander Rodríguez Camacho

“… Introducción: La fibrilación auricular o atrial fue considerada durante mucho tiempo como una alternativa al ritmo sinusal y es en la actualidad un serio problema de salud en muchos países del mundo, a la cual se le asocian muchos factores de riesgo como la insuficiencia cardiaca, la hipertensión arterial y la diabetes mellitus. Es la arritmia más prevalente en la práctica clínica. …”
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New-onset gastrointestinal disorders in COVID-19 patients 3.5 years post-infection in the inner-city population in the Bronx by Sagar Changela, Samad Ashraf, Justin Y. Lu, Kevin E. Duong, Sonya Henry, Stephen H. Wang, Tim Q. Duong

“…COVID-19 patients had an elevated risk of developing new GID (adjusted HR = 1.18 (95% CI 1.12–1.25) compared to propensity-matched controls, after adjusting for confounders that included smoking, obesity, diabetes, hypertension. These findings underscore the need for additional research and follow-up of at-risk individuals for developing GID post infection.…”
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Predictors of Insulin Resistance in Children versus Adolescents with Obesity by Yvette E. Lentferink, Marieke A. J. Elst, Catherijne A. J. Knibbe, Marja M. J. van der Vorst

“…Obesity is a risk factor to develop metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM). Insulin resistance (IR) plays a major part in both. …”
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Research Advances in the Role of Cereal Dietary Fiber in Modulating Glucose and lipid Metabolism via the Gut Microbiota-Bile Acid by DONG Hong-wang, QI Wen-tao, PENG Wen-ting, SONG Ge, FANG Wei

“…Disorders in glucose and lipid metabolism are closely linked to chronic metabolic diseases, including obesity, non-alcoholic fatty liver, hyperlipidemia and diabetes. Cereal dietary fiber, as a prebiotic, can lower blood sugar and lipid levels while promoting metabolic balance. …”
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Positive self-perceived health of octogenarians participating in community groups by Rodrigo Krug, Ione Schneider, Susana Confortin, Danielle Antes, Maruí Giehl, Marize Lopes, André Xavier, Eleonora d'Orsi, Giovana Mazo

“…The factors associated with positive self-perceived health were as follows: to receive a monthly income higher than six minimum wages (PR=1.39; 95%CI=0.91-2.11), to smoke currently (PR=1.75; 95%CI=1.25-2.46), to be physically active during leisure time (PR=1.33; 95%CI=1.06-1.67), to have arthritis or rheumatism (PR=0.55; 95%CI=0.37-0.80), diabetes (PR=0.54; 95%CI=0.37-0.79) and cardiovascular disease (OR=0.71; 95%CI=0.53-0.95), apart from using medications (PR=0.74; 95%CI=0.60-0.91). …”
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Bacteriemias en la unidad de cuidados intensivos by Alexis Hernández Torres, Alberto García Gómez, Juan Carlos Pradere Pensado, Yoandra Adela Rives, Eglis Fernández Castillo

“…El foco de infección más frecuente fue el sistema respiratorio y los factores de riesgo presentes fueron: nutrición parenteral, diabetes mellitus, neoplasia y edad superior a los 60 años. …”
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Height Constitutes an Important Predictor of Mortality in End-Stage Renal Disease by Tsuneo Takenaka, Takahiko Sato, Hitoshi Hoshi, Nobutaka Kato, Keita Sueyoshi, Masahiro Tsuda, Yusuke Watanabe, Hiroshi Takane, Yoichi Ohno, Hiromichi Suzuki

“…Fifty two hypertensive patients with type 2 diabetic nephropathy receiving hemodialysis and 52 patients with nondiabetic nephropathy were enrolled. …”
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Influence of Artificial Sweetener on Human Blood Glucose Concentration by Ilse Skokan, P. Christian Endler, Beatrix Wulkersdorfer, Dieter Magometschnigg, Heinz Spranger

“…Known for their low energetic value they serve especially diabetic and adipose patients as sugar substitutes. …”
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To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations by Holli-Joi Sullivan, Xiaoyan Wang, Shaina Nogle, Siyan Liao, Chun Wu

“…Chiglitazar is a promising new-generation insulin sensitizer with low reverse effects for the treatment of type II diabetes mellitus (T2DM) and has shown activity as a nonselective pan-agonist to the human peroxisome proliferator-activated receptors (PPARs) (i.e., full activation of PPARγ and a partial activation of PPARα and PPARβ/δ). …”
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Impact of Corticosteroid Dosing and Glucose Levels on Readmission Rates in Chronic Obstructive Pulmonary Disease Exacerbation Patients: A Study from Tertiary Care Center by Amirullah, Pavan N Kumar, Deepak

“…Subgroup analysis revealed no significant trends in readmission rates among patients with prior diabetes diagnoses. Conclusion: The study indicates that adherence to recommended corticosteroid dosing and average glucose levels during hospitalization do not significantly affect readmission rates for COPD exacerbations. …”
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Plants from Arid Zones of Mexico: Bioactive Compounds and Potential Use for Food Production by Isabel Márquez-Rangel, Mario Cruz, Alberto A. Neira-Vielma, Sonia N. Ramírez-Barrón, Pedro Aguilar-Zarate, Ruth Belmares

“…This has led to an opportunity to study arid zone plants as food sources that have potential biological activities and improve consumer health. (2) Methods: In this work, we review recent research focused on the traditional use and importance of arid zone plants, their nutritional contribution, and their beneficial effects on health when they are consumed; these effects are primarily because of their antioxidant activity, which inhibits free radicals and contributes to improved nutrition and benefits consumer health. (3) Results: Several plant-based functional food studies have shown that the consumption of bioactive compounds is a complement to drugs for preventing some chronic degenerative diseases, such as gastrointestinal diseases, diabetes, and obesity. (4) Conclusions: Given all of the previously mentioned factors, plants from arid zones are potential sources for obtaining bioactive compounds with low water requirements.…”
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Smoking as a causative factor in chronic kidney disease: a two-sample Mendelian randomization study by Yue Yang, Zheng Zhang, Hai-tao Lu, Qian-qian Xu, Li Zhuo, Wen-ge Li

“…Additionally, the effect of smoking on CKD was mediated by factors such as body mass index, cardiovascular disease, hypertension, and type 2 diabetes. These findings identify smoking as a contributing factor to CKD and suggest that reducing smoking prevalence could significantly lower the incidence of CKD in the population.…”
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Sulforaphane acutely activates multiple starvation response pathways by Kendra S. Plafker, Constantin Georgescu, Nathan Pezant, Atul Pranay, Scott M. Plafker

“…SFN ameliorates various disease models in rodents (e.g., cancer, diabetes, seizures) that are likewise mitigated by dietary restrictions leading us to test the hypothesis that this compound elicits cellular responses consistent with being a fasting/caloric restriction mimetic. …”
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Feasibility of engaging parents attending an adult weight management programme with child weight management support: a mixed methods study by Russell Jago, Julian PH Shield, Aidan Searle, Ruth Mears, Deborah Sharp

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Detection and Quantification of the Relationship between the Ratio of Triglycerides over High-Density Lipoprotein Cholesterol and the Level of Serum Uric Acid: One Cross-Sectional... by Yuexi Li, Yuhan Luo, Qiaoli Wang, Xiaoqin Liu

“…Hyperuricemia acts as an independently known risk factor for diabetes, cardiovascular disease, and gout. It was previously reported that the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) is not only an important marker of cardiovascular disease, stroke, atherosclerosis, and insulin resistance but is also associated with an elevated level of serum uric acid. …”
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Acute Kidney Injury in a Case Series of Patients with Confirmed COVID-19 (Coronavirus Disease 2019): Role of Angiotensin-Converting Enzyme 2 and Renin-Angiotensin System Blockade by Avantika Chenna, Venu Madhav Konala, Subhasish Bose, Sasmit Roy, Bhaskar Reddy Madhira, Vijay Gayam, Srikanth Naramala, Sreedhar Adapa

“…The renin-angiotensin system plays a very critical role in hypertension, diabetes, and kidney and heart diseases. The blockade of the renin-angiotensin system results in the prevention of progression of renal and cardiac damage. …”
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Specialized Medical Weight Management Intervention for High-Risk Obesity by Gitanjali Srivastava, Chelsea Paris, Jessica Johnson, Emma Barnes, Brittany L. Cunningham, C. J. Stimson, Kevin D. Niswender, Sabrina J. Poon

“…The prevalence of any obesity-related medical condition was 54.1%; at least a quarter of the patients had either prediabetes or Type 2 diabetes mellitus, approximately a third had hypertension, and over 8% had hyperlipidemia. …”
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Free Radical Scavenging, Anti-Infectious, and Toxicity Activities from Stenochlaena palustris (Burm.f.) Bedd. Extracts by Rudi Hendra, Rohimatul Khodijah, Muhammad Almurdani, Yuli Haryani, Ari Satia Nugraha, Neni Frimayanti, Hilwan Yuda Teruna, Rizky Abdulah

“…It has been used to treat wound healing, infection, and diabetes. This study looked into the free radical scavenging activity, antiplasmodial activity, toxicity, and antibacterial activity against pathogenic bacteria. …”
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