Meeting Report on “The International Congress on Autoimmune Pre-disease (2024)” by Justus Ohmes, Afsaneh Mehrpouyan, Julia Wimmer-Groß, Abdul Razzaque Ahmed, Kyle T. Amber, Swayanka Biswas, Angela Christiano, Shirin Emtenani, Stephanie Goletz, Jennifer Elisabeth Hundt, Laura Kirchhoff, Khalaf Kridin, Julie Lasselin, Matthias Laudes, Wing Yu Lee, Ralf J. Ludwig, Sripriya Murthy, Sadegh Mousavi, Tamas Nemeth, Mareike Neumann, Isa Popken, Rochi Saurabh, Alessia Maria Sbaraglia, Jovan Schanzenbacher, Carolin Schmidt, Leon F. Schmidt-Jimènez, Christian Willi Scheiner, Mareile Schlotfeldt, Nora Schoell, Farbod Bahreini, Sarah Stenger

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The Adaptation, Implementation, and Performance Evaluation of Intake24, a Digital 24-h Dietary Recall Tool for South Asian Populations: The South Asia Biobank by Divya Bhagtani, Birdem Amoutzopoulos, Toni Steer, David Collins, Suzanna Abraham, Bridget A Holmes, Baldeesh K Rai, Rajendra Pradeepa, Sara Mahmood, Abu Ahmed Shamim, Poorvee Mathur, Lathika Athauda, Laksara De Silva, Khadija I Khawaja, Vinitaa Jha, Anuradhani Kasturiratne, Prasad Katulanda, Malay K Mridha, Ranjit M Anjana, John C Chambers, Polly Page, Nita G Forouhi

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Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive B... by Ming Zhai, Peipei Luan, Yefei Shi, Bo Li, Jianhua Kang, Fan Hu, Mingjie Li, Lei Du, Donglei Zhou, Weixia Jian, Wenhui Peng

“…Gene Expression Omnibus (GEO) datasets (GSE27951, GSE55200, and GSE26637) of insulin-resistant individuals or type 2 diabetes patients and normal controls were downloaded to get differently expressed genes (DEGs), and GO and KEGG pathway analyses were performed. …”
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Enhancing the Health-Promoting Effects of Tomato Fruit for Biofortified Food by Assunta Raiola, Maria Manuela Rigano, Roberta Calafiore, Luigi Frusciante, Amalia Barone

“…In this review, we will summarize the recent progress on tomatoes nutritional importance and mechanisms of action of different phytochemicals against inflammation processes and prevention of chronic noncommunicable diseases (e.g., obesity, diabetes, coronary heart disease, and hypertension). …”
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Therapeutic Implications of Targeting Energy Metabolism in Breast Cancer by Meena K. Sakharkar, Babita Shashni, Karun Sharma, Sarinder K. Dhillon, Prabhakar R. Ranjekar, Kishore R. Sakharkar

“…PPARγ agonists have been reported as a new and potentially efficacious treatment of inflammation, diabetes, obesity, cancer, AD, and schizophrenia. Since cancer cells show dysregulation of glycolysis they are potentially manageable through changes in metabolic environment. …”
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Crosstalk between the Gut and Brain in Ischemic Stroke: Mechanistic Insights and Therapeutic Options by Wenjing Huang, Luwen Zhu, Wenjing Song, Mei Zhang, Lili Teng, Minmin Wu

“…This review summarizes the role of MGBA signaling in the development of stroke risk factors such as aging, hypertension, obesity, diabetes, and atherosclerosis, as well as changes in the microbiota in experimental or clinical populations. …”
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Insulin Resistance and Endothelial Dysfunction Constitute a Common Therapeutic Target in Cardiometabolic Disorders by A. Janus, E. Szahidewicz-Krupska, G. Mazur, A. Doroszko

“…This paper summarises the common therapeutic targets for insulin resistance, endothelial dysfunction, and vascular inflammatory reaction at molecular level and analyses the potential pleiotropic effects of drugs used currently in management of cardiovascular disease, metabolic syndrome, and diabetes.…”
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Procedural Treatments for Knee Osteoarthritis: A Review of Current Injectable Therapies by Lisa M. Billesberger, Kyle M. Fisher, Yawar J. Qadri, Richard L. Boortz-Marx

“…In addition to pain and disability, osteoarthritis is associated with depression, comorbid conditions such as diabetes, and increased caregiver burden. It is predicted to cost the Canadian healthcare system $7.6 billion dollars by 2031. …”
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A Role for Folate in Microbiome-Linked Control of Autoimmunity by Christine Mölzer, Heather M. Wilson, Lucia Kuffova, John V. Forrester

“…The microbiome exerts considerable control over immune homeostasis and influences susceptibility to autoimmune and autoinflammatory disease (AD/AID) such as inflammatory bowel disease (IBD), multiple sclerosis (MS), type 1 diabetes (T1D), psoriasis, and uveitis. In part, this is due to direct effects of the microbiome on gastrointestinal (GI) physiology and nutrient transport, but also to indirect effects on immunoregulatory controls, including induction and stabilization of T regulatory cells (Treg). …”
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Empty Calories in Processed Foods: A Comprehensive Review of Dietary Implications by Yusuf Sarkingobir, Yusuf Yahaya Miya

“…The presence of contents of empty calories elicit many effects such as obesity, diabetes, heart disease, fatigue, mental disorders, insatiety, etc. …”
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Results of thrombolytic treatment with recombinant streptokinase in elderly and non elderly patients. by René Tomás Manso Fernández, Francisco Valladares Carvajal, Claudio González Rodríguez., Marcos D. Iraola Ferrer

“…<strong>Results</strong>: The presence of the infarct was more frequent in males (68,31%) mainly associated to the smoking habit, Hypertension, and cholesterolemia in patients less than 74 years of age and in those patients aged 75 or more, the infarct was associated to Hypertension and Diabetes. The most affected side of the heart was the anterior part(44,6%), and the thrombolitic treatment was developd in an average of 211, 76 minutes. …”
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Evaluation of anthropometric indices as predictors of metabolic syndrome: 3-year cohort in Ecuadorian military personnel by German Geovanny Muñoz Gualán, Alberth Patricio Muñoz Gualán

“…Results: The study shows an overweight military population, with a prevalence of metabolic syndrome: according to Asociación Latinoamericana de Diabetes criteria of 1 %, 1.66 % and 0.76 %, in the years 2019, 2020 and 2021 respectively; in contrast, according to Adult Treatment Panel III criteria, with a prevalence of 6.67 %, 6.31 % and 5.70 % in the years 2019, 2020 and 2021 respectively. …”
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Pharmacognostic evaluation of Lasimorpha senegalensis schott leaves (Araceae) by Ginikachukwu MaryRose Okoh, Obinna Sabastin Onugwu, Obodike Christopher Ezugwu

“… The leaves of Lasimorpha senegalensis Schott (Araceae) have long been utilized in conventional medicine to treat conditions like diabetes, inflammation, malaria, oxidative stress, and fever. …”
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Junctional Bradikardia pada Pasien Hiperkalemia by Cokorda Istri Padmi Suwari, Bayu Puradipa, Ni Luh Eka Sriayu Wulandari

“…It has been reported that a 76 years old woman with type 2 diabetes mellitus, hyperkalemia and suspected coronary artery disease complaining about palpitation. …”
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Risk Factors for Obesity un Adolescents from the Tulcán Popular Housing Neighborhood by Mayra Jeaneth Jiménez Jiménez

“…<strong>Foundation:</strong> obesity is caused by multiple factors that can significantly affect people's lives, causing serious health problems and diseases such as hypertension, diabetes and dyslipidemia, among others. <br /><strong>Objective:</strong> to describe the risk factors causing obesity in adolescents from the popular housing neighborhood of Tulcán, Ecuador. …”
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Masked Hypotension due to Elevated Venous Pressure in a Patient with Complex Adult Congenital Heart Disease by Wytch Rigger, Sean P. Javaheri, Gyanendra K. Sharma, Norris Stanley Nahman, Mark Sheynshteyn, Neal L. Weintraub

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Do Individuals with Misophonia Experience Challenges with Their Auditory Binaural Interaction and Integration Skills? by Hrishitha Valia Madappally, Kavassery Venkateswaran Nisha, Prashanth Prabhu

“…Individuals with a history of otological complaints, noise exposure, ototoxic medications, tinnitus, hyperacusis, diabetes, or hypertension were excluded from the study. …”
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The Effect Of Andaliman Fruit (Zanthoxylum Acanthopodium) Extract On Oxidative Stress In The Pancreas Of Rats (Ratus Norvegicus) Induced By D-Galactose by Felix Hartanto, Chrismis Novalinda Ginting, Linda Chiuman

“…Damage to the pancreas causes degenerative diseases, one of which is Diabetes Mellitus, which often occurs in old age. The efforts to reduce the occurrence of ROS due to aging is to consume antioxidants. …”
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Drug Advances in NAFLD: Individual and Combination Treatment Strategies of Natural Products and Small-Synthetic-Molecule Drugs by Xing Wan, Jingyuan Ma, He Bai, Xuyang Hu, Yanna Ma, Mingjian Zhao, Jifeng Liu, Zhijun Duan

“…Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver disease and is closely associated with metabolic diseases such as obesity, type 2 diabetes mellitus (T2DM), and metabolic syndrome. However, effective treatment strategies for NAFLD are still lacking. …”
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Herpes Simplex Virus Type II Infection of Ileum Mesothelium: A Case Report and Review of the Literature by SAC Medlicott, VG Falck, KB Laupland, M Akbari, PL Beck

“…However, anecdotal examples of visceral HSV disease and viremia have complicated type I diabetes. A case of a 53-year-old type I diabetic patient with bowel obstruction one week subsequent to bronchitis is reported. …”
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